BG107624A - Бициклени пиролил амиди като гликоген фосфорилазни инхибитори - Google Patents

Бициклени пиролил амиди като гликоген фосфорилазни инхибитори Download PDF

Info

Publication number
BG107624A
BG107624A BG107624A BG10762403A BG107624A BG 107624 A BG107624 A BG 107624A BG 107624 A BG107624 A BG 107624A BG 10762403 A BG10762403 A BG 10762403A BG 107624 A BG107624 A BG 107624A
Authority
BG
Bulgaria
Prior art keywords
carbamoyl
pyrrole
thieno
dichloro
alkyl
Prior art date
Application number
BG107624A
Other languages
Bulgarian (bg)
English (en)
Inventor
Julie B. Bartlet
Sue Freeman
Peter Kenny
Andrew Morley
Raul Whittamore
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BG107624A publication Critical patent/BG107624A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BG107624A 2000-09-06 2003-03-10 Бициклени пиролил амиди като гликоген фосфорилазни инхибитори BG107624A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0021831.3A GB0021831D0 (en) 2000-09-06 2000-09-06 Chemical compounds
PCT/SE2001/001880 WO2002020530A1 (en) 2000-09-06 2001-08-31 Bicyclic pyrrolyl amides as glucogen phosphorylase inhibitors

Publications (1)

Publication Number Publication Date
BG107624A true BG107624A (bg) 2004-01-30

Family

ID=9898927

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107624A BG107624A (bg) 2000-09-06 2003-03-10 Бициклени пиролил амиди като гликоген фосфорилазни инхибитори

Country Status (31)

Country Link
US (1) US20030232875A1 (de)
EP (1) EP1317459B1 (de)
JP (1) JP2004508376A (de)
KR (1) KR100802369B1 (de)
CN (2) CN1264846C (de)
AT (1) ATE263772T1 (de)
AU (2) AU2001282833B2 (de)
BG (1) BG107624A (de)
BR (1) BR0113606A (de)
CA (1) CA2417594A1 (de)
CZ (1) CZ2003616A3 (de)
DE (1) DE60102710T2 (de)
DK (1) DK1317459T3 (de)
EE (1) EE200300083A (de)
ES (1) ES2217183T3 (de)
GB (1) GB0021831D0 (de)
HK (1) HK1055299A1 (de)
HU (1) HUP0400784A3 (de)
IL (1) IL154291A0 (de)
IS (1) IS2110B (de)
MX (1) MXPA03001512A (de)
NO (1) NO20031024D0 (de)
NZ (1) NZ524011A (de)
PL (1) PL361024A1 (de)
PT (1) PT1317459E (de)
RU (1) RU2003104013A (de)
SK (1) SK2592003A3 (de)
TR (1) TR200401659T4 (de)
UA (1) UA73781C2 (de)
WO (1) WO2002020530A1 (de)
ZA (1) ZA200301013B (de)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5271699A1 (es) 2000-01-24 2003-04-30 Pfizer Prod Inc Procedimiento para el tratamiento de cardiomiopatia utilizando inhibidores de la glucogeno fosforilasa
PE20020856A1 (es) 2001-02-13 2002-11-11 Aventis Pharma Gmbh 1,2,3,4-tetrahidronaftil aminas aciladas
TWI243164B (en) 2001-02-13 2005-11-11 Aventis Pharma Gmbh Acylated indanyl amines and their use as pharmaceuticals
GB0205175D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205162D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205166D0 (en) * 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205170D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205165D0 (en) * 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205176D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
IL164249A0 (en) * 2002-04-11 2005-12-18 Aventis Pharma Gmbh Acyl-3-carboxphenylurea derivatives, processes forpreparing them and their use
DE10215908B4 (de) * 2002-04-11 2005-08-18 Aventis Pharma Deutschland Gmbh Acyl-3-carboxyphenyl-harnstoffderivate und deren Verwendung als Arzneimittel
US7057046B2 (en) * 2002-05-20 2006-06-06 Bristol-Myers Squibb Company Lactam glycogen phosphorylase inhibitors and method of use
DE10225635C1 (de) * 2002-06-07 2003-12-24 Aventis Pharma Gmbh N-Benzoylureido-Zimtsäurederivate, Verfahren zu deren Herstellung und deren Verwendung
DE50311954D1 (de) * 2002-06-17 2009-11-12 Saltigo Gmbh Verfahren zur Herstellung von mono-N-sulfonylierten Diaminen
MXPA05000055A (es) * 2002-07-11 2005-04-08 Aventis Pharma Gmbh Acilureas sustituidas con urea y uretano, metodos para su produccion y su uso.
EP1388535A1 (de) * 2002-08-07 2004-02-11 Aventis Pharma Deutschland GmbH Acylierte Arylcycloalkylamine und ihre Anwendung als Arzneimittelwirkstoff
US7186735B2 (en) 2002-08-07 2007-03-06 Sanofi-Aventis Deutschland Gmbh Acylated arylcycloalkylamines and their use as pharmaceuticals
GB0222909D0 (en) 2002-10-03 2002-11-13 Astrazeneca Ab Novel process and intermediates
GB0222912D0 (en) * 2002-10-03 2002-11-13 Astrazeneca Ab Novel process and intermediates
BR0316099A (pt) * 2002-11-07 2005-09-27 Pfizer Prod Inc Agentes antidiabéticos
WO2004092158A1 (en) 2003-04-17 2004-10-28 Pfizer Products Inc. Carboxamide derivatives as anti-diabetic agents
US7405210B2 (en) 2003-05-21 2008-07-29 Osi Pharmaceuticals, Inc. Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase
NZ543482A (en) * 2003-05-21 2009-02-28 Prosidion Ltd Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phoshorylase
WO2004113345A1 (ja) * 2003-06-20 2004-12-29 Japan Tobacco Inc. 縮合ピロール化合物及びその医薬用途
GB0318464D0 (en) * 2003-08-07 2003-09-10 Astrazeneca Ab Chemical compounds
GB0318463D0 (en) * 2003-08-07 2003-09-10 Astrazeneca Ab Chemical compounds
GB0319759D0 (en) * 2003-08-22 2003-09-24 Astrazeneca Ab Chemical compounds
GB0319690D0 (en) * 2003-08-22 2003-09-24 Astrazeneca Ab Chemical compounds
WO2005020985A1 (en) * 2003-08-29 2005-03-10 Astrazeneca Ab Indolamide derivatives which possess glycogen phosphorylase inhibitory activity
WO2005020986A1 (en) * 2003-08-29 2005-03-10 Astrazeneca Ab Heterocyclic amide derivatives which posses glycogen phosphorylase inhibitory activity
GB0320422D0 (en) * 2003-08-30 2003-10-01 Astrazeneca Ab Chemical compounds
CN1922149A (zh) 2003-12-29 2007-02-28 塞普拉科公司 吡咯和吡唑daao抑制剂
US7453002B2 (en) 2004-06-15 2008-11-18 Bristol-Myers Squibb Company Five-membered heterocycles useful as serine protease inhibitors
WO2006055462A1 (en) * 2004-11-15 2006-05-26 Bristol-Myers Squibb Company 2-amino-4-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
WO2006055435A1 (en) 2004-11-15 2006-05-26 Bristol-Myers Squibb Company 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors
US7365061B2 (en) 2004-11-15 2008-04-29 Bristol-Myers Squibb Company 2-Amino-3-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
US7214704B2 (en) 2004-11-15 2007-05-08 Bristol-Myers Squibb Company 2-Amino-1-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
WO2006059165A1 (en) * 2004-12-02 2006-06-08 Prosidion Limited Pyrrolopyridine-2-carboxylic acid amide derivative useful as inhibitor of glycogen phosphorylase
WO2006059163A1 (en) * 2004-12-02 2006-06-08 Prosidion Limited Treatment of diabetes with glycogen phosphorylase inhibitors
ATE506951T1 (de) * 2005-01-19 2011-05-15 Merck Sharp & Dohme Als inhibitoren von beta-secretase aktive tertiäre carbinamine mit substituierten heterocyclen zur behandlung der alzheimer- krankheit
US20100137397A1 (en) * 2005-02-05 2010-06-03 Astrazeneca Ab Chemical Compounds
EP1848693A1 (de) * 2005-02-05 2007-10-31 AstraZeneca AB Indanamidderivate mit glykogenphosphorylase hemmender wirkung
NZ569630A (en) 2006-01-06 2011-09-30 Sepracor Inc Cycloalkylamines as monoamine reuptake inhibitors
CA2636275C (en) 2006-01-06 2013-02-12 Sepracor Inc. Tetralone-based monoamine reuptake inhibitors
DK2013835T3 (en) 2006-03-31 2015-12-14 Sunovion Pharmaceuticals Inc Preparation of chiral amides and AMINES
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
US7884124B2 (en) 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
EP2298772A1 (de) * 2006-10-18 2011-03-23 Takeda Pharmaceutical Company Limited Kondensierte heterozyklische Verbindungen
US7902252B2 (en) 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
KR101581289B1 (ko) 2007-05-31 2015-12-31 세프라코 아이엔시. 모노아민 재흡수 억제제로서 페닐 치환된 시클로알킬아민
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US20100152200A1 (en) * 2008-11-17 2010-06-17 The Regents Of The University Of Michigan Alphavirus inhibitors and uses thereof
WO2012027331A1 (en) 2010-08-27 2012-03-01 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
PL3004138T3 (pl) 2013-06-05 2024-07-29 Bausch Health Ireland Limited Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie
MX2017002610A (es) 2014-08-29 2017-10-11 Tes Pharma S R L INHIBIDORES DE ACIDO A-AMINO-ß-CARBOXIMUCONICO SEMIALDEHIDO DESCARBOXILASA.
TWI763630B (zh) * 2015-07-02 2022-05-11 瑞士商赫孚孟拉羅股份公司 雙環內醯胺及其使用方法
JP6974331B2 (ja) * 2016-02-05 2021-12-01 デナリ セラピューティクス インコーポレイテッドDenali Therapeutics Inc. 化合物、組成物及び方法
BR112019007543A2 (pt) 2016-10-14 2019-07-02 Tes Pharma S R L inibidores de ácido alfa-amino-beta-carboximuconico semialdeido decarboxilase
EP3526219B1 (de) 2016-10-17 2021-12-15 F. Hoffmann-La Roche AG Bicyclische pyridonlactame und verfahren zur verwendung davon
US11072607B2 (en) 2016-12-16 2021-07-27 Genentech, Inc. Inhibitors of RIP1 kinase and methods of use thereof
CN112074519B (zh) 2018-04-20 2024-08-02 豪夫迈·罗氏有限公司 作为rip1激酶抑制剂用于治疗例如肠易激综合征(ibs)的化合物
WO2020104456A1 (en) 2018-11-20 2020-05-28 Tes Pharma S.R.L INHIBITORS OF α-AMINO-β-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE
CA3163206A1 (en) * 2019-11-27 2021-06-03 Riken G9a inhibitor

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3706810A (en) * 1970-09-15 1972-12-19 American Cyanamid Co N-morpholinoalkyl-thieno(3,2-b)pyrrole-5-carboxamides
US4692522A (en) * 1985-04-01 1987-09-08 Merck & Co., Inc. Benzofused lactams useful as cholecystokinin antagonists
US4668769A (en) * 1985-08-02 1987-05-26 Hoover Dennis J Oxa- and azahomocyclostatine polypeptides
US4599198A (en) * 1985-08-02 1986-07-08 Pfizer Inc. Intermediates in polypeptide synthesis
US4720503A (en) * 1985-08-02 1988-01-19 Merck & Co., Inc. N-substituted fused-heterocyclic carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors
FR2601368B1 (fr) * 1986-07-08 1989-04-07 Synthelabo Derives de nitrofuranne, leur preparation et leur application en therapeutique.
DE3629545A1 (de) * 1986-08-30 1988-03-10 Bayer Ag Dihydropyridinverbindungen, verfahren zu ihrer herstellung und ihre verwendung
US4751231A (en) * 1987-09-16 1988-06-14 Merck & Co., Inc. Substituted thieno[2,3-b]pyrrole-5-sulfonamides as antiglaucoma agents
ES2081747B1 (es) * 1993-09-07 1997-01-16 Esteve Labor Dr Amidas derivadas de tienopirroles, su preparacion y su aplicacion como medicamentos.
US5863903A (en) * 1994-03-09 1999-01-26 Novo Nordisk A/S Use of hydroxy alkyl piperidine and pyrrolidine compounds to treat diabetes
FR2723739B1 (fr) * 1994-08-19 1997-02-14 Sanofi Sa Derives de glycinamide, procedes pour leur preparation et medicaments les contenant.
WO1996039384A1 (en) * 1995-06-06 1996-12-12 Pfizer, Inc. Substituted n-(indole-2-carbonyl)-glycinamides and derivatives as glycogen phosphorylase inhibitors
US5952322A (en) * 1996-12-05 1999-09-14 Pfizer Inc. Method of reducing tissue damage associated with non-cardiac ischemia using glycogen phosphorylase inhibitors
US5998463A (en) * 1998-02-27 1999-12-07 Pfizer Inc Glycogen phosphorylase inhibitors
JP2002506073A (ja) * 1998-03-12 2002-02-26 ノボ ノルディスク アクティーゼルスカブ プロテイン・チロシン・ホスファターゼ（ＰＴＰａｓｅｓ）のモジュレーター
PT1088824E (pt) * 1999-09-30 2004-04-30 Pfizer Prod Inc Pirrolil-amidas biciclicas como inibidores de glicogenio-fosforilase
CO5271699A1 (es) * 2000-01-24 2003-04-30 Pfizer Prod Inc Procedimiento para el tratamiento de cardiomiopatia utilizando inhibidores de la glucogeno fosforilasa
US6555569B2 (en) * 2000-03-07 2003-04-29 Pfizer Inc. Use of heteroaryl substituted N-(indole-2-carbonyl-) amides for treatment of infection
US7057046B2 (en) * 2002-05-20 2006-06-06 Bristol-Myers Squibb Company Lactam glycogen phosphorylase inhibitors and method of use

Also Published As

Publication number Publication date
CN1264846C (zh) 2006-07-19
BR0113606A (pt) 2003-06-24
HUP0400784A3 (en) 2007-09-28
UA73781C2 (en) 2005-09-15
JP2004508376A (ja) 2004-03-18
PT1317459E (pt) 2004-08-31
WO2002020530A1 (en) 2002-03-14
ZA200301013B (en) 2004-05-05
RU2003104013A (ru) 2004-08-20
EE200300083A (et) 2004-12-15
CN1896078A (zh) 2007-01-17
KR100802369B1 (ko) 2008-02-14
NZ524011A (en) 2004-08-27
CZ2003616A3 (cs) 2003-05-14
ES2217183T3 (es) 2004-11-01
HUP0400784A2 (hu) 2004-07-28
US20030232875A1 (en) 2003-12-18
AU8283301A (en) 2002-03-22
CA2417594A1 (en) 2002-03-14
KR20030025305A (ko) 2003-03-28
AU2001282833B2 (en) 2006-07-06
EP1317459A1 (de) 2003-06-11
PL361024A1 (en) 2004-09-20
ATE263772T1 (de) 2004-04-15
IS2110B (is) 2006-05-15
IL154291A0 (en) 2003-09-17
CN1473163A (zh) 2004-02-04
EP1317459B1 (de) 2004-04-07
GB0021831D0 (en) 2000-10-18
DE60102710T2 (de) 2005-04-14
HK1055299A1 (en) 2004-01-02
NO20031024L (no) 2003-03-05
IS6727A (is) 2003-02-24
MXPA03001512A (es) 2003-06-09
DK1317459T3 (da) 2004-07-12
TR200401659T4 (tr) 2004-09-21
SK2592003A3 (en) 2003-08-05
DE60102710D1 (de) 2004-05-13
NO20031024D0 (no) 2003-03-05

Similar Documents

Publication Publication Date Title
BG107624A (bg) Бициклени пиролил амиди като гликоген фосфорилазни инхибитори
AU2001282833A1 (en) Bicyclic pyrrolyl amides as glucogen phosphorylase inhibitors
US9447100B2 (en) Substituted pyrazolo[1,5-A] pyrimidines as calcium receptor modulating agents
KR101312993B1 (ko) 히스톤 데아세틸라아제의 억제제
MXPA04008614A (es) Derivados de amida heterociclica como inhibidores de la glucogeno-fosforilasa.
EA028991B1 (ru) Гетероциклические амиды в качестве ингибиторов киназы
ES2276092T3 (es) Derivados de amidas heterociclicas que poseen actividad inhibidora de glucogeno-fosforilasa.
ES2309537T3 (es) Derivados de amida heterociclica que poseen actividad inhibidora de la glucogeno fosforilasa.
JP2020519596A (ja) Ｉｒａｋ−４阻害剤として有用なチエノピリジンおよびベンゾチオフェン
ES2315676T3 (es) Derivados de indolamida que poseen actividad inhibidora de la glucogeno fosforilasa.
JP5377313B2 (ja) セリンヒドロラーゼ阻害剤
PT1797099E (pt) Compostos de piperidinilamino-tieno[2,3-d]pirimidina
KR20030045187A (ko) 도파민 ｄ₃수용체 조절제 (정신병 치료제)로서 유용한테트라히드로벤즈아제핀 유도체
MX2007009784A (es) Compuestos moduladores de receptores de androgenos y metodos.
RU2238274C2 (ru) Тиенопиримидины, способ их получения, фармацевтический препарат и способ его получения
MXPA04008612A (es) Derivados de indolamida que tienen actividad inhibitoria de glucogeno-fosforilasa.
ES2380236T3 (es) Compuesto de amida heterocíclica y uso del mismo
CN101006055B (zh) 作为酪蛋白激酶Iε抑制剂的3-取代的-5-和6-氨基烷基吲哚-2-羧酸酰胺以及相关类似物