TR200401659T4 - Glikojen fosforilaz inhibitörleri olarak bisiklik pirolil amidler - Google Patents
Glikojen fosforilaz inhibitörleri olarak bisiklik pirolil amidlerInfo
- Publication number
- TR200401659T4 TR200401659T4 TR2004/01659T TR200401659T TR200401659T4 TR 200401659 T4 TR200401659 T4 TR 200401659T4 TR 2004/01659 T TR2004/01659 T TR 2004/01659T TR 200401659 T TR200401659 T TR 200401659T TR 200401659 T4 TR200401659 T4 TR 200401659T4
- Authority
- TR
- Turkey
- Prior art keywords
- glycogen phosphorylase
- phosphorylase inhibitors
- amides
- bicyclic
- amide derivatives
- Prior art date
Links
- -1 Bicyclic pyrrolyl amides Chemical class 0.000 title abstract 3
- 102000007390 Glycogen Phosphorylase Human genes 0.000 title abstract 3
- 108010046163 Glycogen Phosphorylase Proteins 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
(I) formülüne sahip heterosiklik amid türevleri ya da bunlarin farmasötik açidan kabul edilebilir bir tuzu ya da in vivo hidroli edilebilir bir esteri, ki bunlarda-X-Y-Z- degeri-S-CR<4>=CR<5>-,CRCR<4>-S-, -0-CR<4>=CR<5>-, -CR<4>=CR<5>-0-,-N=CR<4>-S-, -S-CR<4>=-, -NR<6>-CR<4>=CR<5>-ve-CR<4>=CR<5>-NR<6>-;arasindan seçilir (kosullara tabi olarak); glikojen fosforilaz engelleyici aktiviteye sahiptir ve dolayisiyla glikojen fosforilaz aktivitesinin artisiyla ilgili hastaliklarin tedavisinde degerlidir. sözü edilen heterosiklik amid türevlerinin ve bunlari içeren farmasötik bilesimlerin üretimine yönelik süreçler tanimlanmistir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0021831.3A GB0021831D0 (en) | 2000-09-06 | 2000-09-06 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200401659T4 true TR200401659T4 (tr) | 2004-09-21 |
Family
ID=9898927
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2004/01659T TR200401659T4 (tr) | 2000-09-06 | 2001-08-31 | Glikojen fosforilaz inhibitörleri olarak bisiklik pirolil amidler |
Country Status (31)
Country | Link |
---|---|
US (1) | US20030232875A1 (tr) |
EP (1) | EP1317459B1 (tr) |
JP (1) | JP2004508376A (tr) |
KR (1) | KR100802369B1 (tr) |
CN (2) | CN1264846C (tr) |
AT (1) | ATE263772T1 (tr) |
AU (2) | AU8283301A (tr) |
BG (1) | BG107624A (tr) |
BR (1) | BR0113606A (tr) |
CA (1) | CA2417594A1 (tr) |
CZ (1) | CZ2003616A3 (tr) |
DE (1) | DE60102710T2 (tr) |
DK (1) | DK1317459T3 (tr) |
EE (1) | EE200300083A (tr) |
ES (1) | ES2217183T3 (tr) |
GB (1) | GB0021831D0 (tr) |
HK (1) | HK1055299A1 (tr) |
HU (1) | HUP0400784A3 (tr) |
IL (1) | IL154291A0 (tr) |
IS (1) | IS2110B (tr) |
MX (1) | MXPA03001512A (tr) |
NO (1) | NO20031024L (tr) |
NZ (1) | NZ524011A (tr) |
PL (1) | PL361024A1 (tr) |
PT (1) | PT1317459E (tr) |
RU (1) | RU2003104013A (tr) |
SK (1) | SK2592003A3 (tr) |
TR (1) | TR200401659T4 (tr) |
UA (1) | UA73781C2 (tr) |
WO (1) | WO2002020530A1 (tr) |
ZA (1) | ZA200301013B (tr) |
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GB0205170D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
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GB0319759D0 (en) * | 2003-08-22 | 2003-09-24 | Astrazeneca Ab | Chemical compounds |
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-
2000
- 2000-09-06 GB GBGB0021831.3A patent/GB0021831D0/en not_active Ceased
-
2001
- 2001-08-31 HU HU0400784A patent/HUP0400784A3/hu unknown
- 2001-08-31 NZ NZ524011A patent/NZ524011A/en unknown
- 2001-08-31 DK DK01961577T patent/DK1317459T3/da active
- 2001-08-31 BR BR0113606-2A patent/BR0113606A/pt not_active IP Right Cessation
- 2001-08-31 PT PT01961577T patent/PT1317459E/pt unknown
- 2001-08-31 EP EP01961577A patent/EP1317459B1/en not_active Expired - Lifetime
- 2001-08-31 ES ES01961577T patent/ES2217183T3/es not_active Expired - Lifetime
- 2001-08-31 KR KR1020037003265A patent/KR100802369B1/ko not_active IP Right Cessation
- 2001-08-31 TR TR2004/01659T patent/TR200401659T4/tr unknown
- 2001-08-31 AU AU8283301A patent/AU8283301A/xx active Pending
- 2001-08-31 UA UA2003021026A patent/UA73781C2/uk unknown
- 2001-08-31 CZ CZ2003616A patent/CZ2003616A3/cs unknown
- 2001-08-31 AT AT01961577T patent/ATE263772T1/de not_active IP Right Cessation
- 2001-08-31 CN CNB018183220A patent/CN1264846C/zh not_active Expired - Fee Related
- 2001-08-31 MX MXPA03001512A patent/MXPA03001512A/es active IP Right Grant
- 2001-08-31 PL PL01361024A patent/PL361024A1/xx unknown
- 2001-08-31 CN CNA2006100818966A patent/CN1896078A/zh active Pending
- 2001-08-31 US US10/344,506 patent/US20030232875A1/en not_active Abandoned
- 2001-08-31 WO PCT/SE2001/001880 patent/WO2002020530A1/en active IP Right Grant
- 2001-08-31 CA CA002417594A patent/CA2417594A1/en not_active Abandoned
- 2001-08-31 AU AU2001282833A patent/AU2001282833B2/en not_active Ceased
- 2001-08-31 IL IL15429101A patent/IL154291A0/xx unknown
- 2001-08-31 RU RU2003104013/04A patent/RU2003104013A/ru not_active Application Discontinuation
- 2001-08-31 SK SK259-2003A patent/SK2592003A3/sk unknown
- 2001-08-31 JP JP2002525151A patent/JP2004508376A/ja not_active Withdrawn
- 2001-08-31 DE DE60102710T patent/DE60102710T2/de not_active Expired - Fee Related
- 2001-08-31 EE EEP200300083A patent/EE200300083A/xx unknown
-
2003
- 2003-02-05 ZA ZA200301013A patent/ZA200301013B/en unknown
- 2003-02-24 IS IS6727A patent/IS2110B/is unknown
- 2003-03-05 NO NO20031024A patent/NO20031024L/no not_active Application Discontinuation
- 2003-03-10 BG BG107624A patent/BG107624A/bg unknown
- 2003-10-16 HK HK03107519A patent/HK1055299A1/xx not_active IP Right Cessation
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