BR0113606A - Composto, composição farmacêutica, e, uso de um composto ou de um sal farmaceuticamente aceitável ou éster hidrolisável in vivo deste - Google Patents

Composto, composição farmacêutica, e, uso de um composto ou de um sal farmaceuticamente aceitável ou éster hidrolisável in vivo deste

Info

Publication number
BR0113606A
BR0113606A BR0113606-2A BR0113606A BR0113606A BR 0113606 A BR0113606 A BR 0113606A BR 0113606 A BR0113606 A BR 0113606A BR 0113606 A BR0113606 A BR 0113606A
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutically acceptable
pharmaceutical composition
acceptable salt
vivo hydrolysable
Prior art date
Application number
BR0113606-2A
Other languages
English (en)
Inventor
Julie B Bartlett
Sue Freeman
Peter Kenny
Andrew Morley
Paul Whittamore
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BR0113606A publication Critical patent/BR0113606A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

"COMPOSTO, COMPOSIçãO FARMACêUTICA, E, USO DE UM COMPOSTO OU DE UM SAL FARMACEUTICAMENTE ACEITáVEL OU ESTER HIDROLISáVEL IN VIVO DESTE". Derivados de amida heterocíclica, de fórmula (I) em que -X-Y-Z é selecionado de -S-CR^ 4^=CR^ 5^-S-, -O-CR^ 4^=CR^ 5^-, -CR^ 4^=CR^ 5^-O-, -N=CR~ 4~-S-, -S-CR^ 4^=N, -NR^ 6^-CR^ 4^=CR^ 5^ e -CR^ 4^=CR^ 5^-NR^ 6^-; ou um sal farmaceuticamente aceitável ou um éster hidrolisável in vivo destes; (com ressalvas); possuem atividade inibidora da fosforilase do glicogênio e conseq³entemente possuem valor no tratamento de estados doentios associados com a atividade aumentada da fosforilase do glicogênio. São descritos processos para a fabricação de ditos derivados de amida heterocíclica e composições farmacêuticas contendo-os.
BR0113606-2A 2000-09-06 2001-08-31 Composto, composição farmacêutica, e, uso de um composto ou de um sal farmaceuticamente aceitável ou éster hidrolisável in vivo deste BR0113606A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0021831.3A GB0021831D0 (en) 2000-09-06 2000-09-06 Chemical compounds
PCT/SE2001/001880 WO2002020530A1 (en) 2000-09-06 2001-08-31 Bicyclic pyrrolyl amides as glucogen phosphorylase inhibitors

Publications (1)

Publication Number Publication Date
BR0113606A true BR0113606A (pt) 2003-06-24

Family

ID=9898927

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0113606-2A BR0113606A (pt) 2000-09-06 2001-08-31 Composto, composição farmacêutica, e, uso de um composto ou de um sal farmaceuticamente aceitável ou éster hidrolisável in vivo deste

Country Status (31)

Country Link
US (1) US20030232875A1 (pt)
EP (1) EP1317459B1 (pt)
JP (1) JP2004508376A (pt)
KR (1) KR100802369B1 (pt)
CN (2) CN1264846C (pt)
AT (1) ATE263772T1 (pt)
AU (2) AU8283301A (pt)
BG (1) BG107624A (pt)
BR (1) BR0113606A (pt)
CA (1) CA2417594A1 (pt)
CZ (1) CZ2003616A3 (pt)
DE (1) DE60102710T2 (pt)
DK (1) DK1317459T3 (pt)
EE (1) EE200300083A (pt)
ES (1) ES2217183T3 (pt)
GB (1) GB0021831D0 (pt)
HK (1) HK1055299A1 (pt)
HU (1) HUP0400784A3 (pt)
IL (1) IL154291A0 (pt)
IS (1) IS2110B (pt)
MX (1) MXPA03001512A (pt)
NO (1) NO20031024L (pt)
NZ (1) NZ524011A (pt)
PL (1) PL361024A1 (pt)
PT (1) PT1317459E (pt)
RU (1) RU2003104013A (pt)
SK (1) SK2592003A3 (pt)
TR (1) TR200401659T4 (pt)
UA (1) UA73781C2 (pt)
WO (1) WO2002020530A1 (pt)
ZA (1) ZA200301013B (pt)

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Also Published As

Publication number Publication date
KR20030025305A (ko) 2003-03-28
SK2592003A3 (en) 2003-08-05
HK1055299A1 (en) 2004-01-02
HUP0400784A2 (hu) 2004-07-28
CA2417594A1 (en) 2002-03-14
CZ2003616A3 (cs) 2003-05-14
RU2003104013A (ru) 2004-08-20
MXPA03001512A (es) 2003-06-09
CN1264846C (zh) 2006-07-19
UA73781C2 (en) 2005-09-15
AU2001282833B2 (en) 2006-07-06
PL361024A1 (en) 2004-09-20
JP2004508376A (ja) 2004-03-18
EE200300083A (et) 2004-12-15
GB0021831D0 (en) 2000-10-18
EP1317459A1 (en) 2003-06-11
NO20031024D0 (no) 2003-03-05
NO20031024L (no) 2003-03-05
IS6727A (is) 2003-02-24
CN1896078A (zh) 2007-01-17
AU8283301A (en) 2002-03-22
HUP0400784A3 (en) 2007-09-28
NZ524011A (en) 2004-08-27
DE60102710D1 (de) 2004-05-13
ES2217183T3 (es) 2004-11-01
TR200401659T4 (tr) 2004-09-21
BG107624A (bg) 2004-01-30
US20030232875A1 (en) 2003-12-18
IL154291A0 (en) 2003-09-17
DE60102710T2 (de) 2005-04-14
IS2110B (is) 2006-05-15
ZA200301013B (en) 2004-05-05
CN1473163A (zh) 2004-02-04
WO2002020530A1 (en) 2002-03-14
KR100802369B1 (ko) 2008-02-14
EP1317459B1 (en) 2004-04-07
ATE263772T1 (de) 2004-04-15
DK1317459T3 (da) 2004-07-12
PT1317459E (pt) 2004-08-31

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012.