DE602005008099D1 - Pyrrolopyridin-2-karbonsäureamid-derivat zur verwendung als inhibitor gegen glykogenphosphorylase - Google Patents

Pyrrolopyridin-2-karbonsäureamid-derivat zur verwendung als inhibitor gegen glykogenphosphorylase

Info

Publication number
DE602005008099D1
DE602005008099D1 DE602005008099T DE602005008099T DE602005008099D1 DE 602005008099 D1 DE602005008099 D1 DE 602005008099D1 DE 602005008099 T DE602005008099 T DE 602005008099T DE 602005008099 T DE602005008099 T DE 602005008099T DE 602005008099 D1 DE602005008099 D1 DE 602005008099D1
Authority
DE
Germany
Prior art keywords
pyrrolopyridine
inhibitor
phosphorylase
glycope
acid derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005008099T
Other languages
English (en)
Inventor
Jozsef Repasi
Andras Szabo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prosidion Ltd
Original Assignee
Prosidion Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prosidion Ltd filed Critical Prosidion Ltd
Publication of DE602005008099D1 publication Critical patent/DE602005008099D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
DE602005008099T 2004-12-02 2005-12-02 Pyrrolopyridin-2-karbonsäureamid-derivat zur verwendung als inhibitor gegen glykogenphosphorylase Active DE602005008099D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63246304P 2004-12-02 2004-12-02
PCT/GB2005/050234 WO2006059165A1 (en) 2004-12-02 2005-12-02 Pyrrolopyridine-2-carboxylic acid amide derivative useful as inhibitor of glycogen phosphorylase

Publications (1)

Publication Number Publication Date
DE602005008099D1 true DE602005008099D1 (de) 2008-08-21

Family

ID=35735250

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005008099T Active DE602005008099D1 (de) 2004-12-02 2005-12-02 Pyrrolopyridin-2-karbonsäureamid-derivat zur verwendung als inhibitor gegen glykogenphosphorylase

Country Status (11)

Country Link
US (1) US8664397B2 (de)
EP (1) EP1819704B1 (de)
JP (1) JP2008521874A (de)
AT (1) ATE400574T1 (de)
DE (1) DE602005008099D1 (de)
DK (1) DK1819704T3 (de)
ES (1) ES2309822T3 (de)
HK (1) HK1107984A1 (de)
PL (1) PL1819704T3 (de)
PT (1) PT1819704E (de)
WO (1) WO2006059165A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
EP2089017A2 (de) 2006-11-02 2009-08-19 Aestus Therapeutics, Inc. Glycolyse-/glycogenolyse-hemmer für schmerzbehandlung
CN103626837B (zh) * 2013-09-30 2016-11-23 承德医学院 含生物可裂解二肽的糖原磷酸化酶抑制剂胆酸类衍生物、其制备方法及医药用途
CN103626826B (zh) * 2013-09-30 2015-10-21 承德医学院 含偶氮键的糖原磷酸化酶抑制剂胆酸类衍生物、其制备方法及医药用途
CN103626825B (zh) * 2013-09-30 2015-10-07 承德医学院 靶向肝脏的糖原磷酸化酶抑制剂胆酸类衍生物、其制备方法及医药用途
CN103819486B (zh) * 2014-01-27 2016-08-17 承德医学院 标记血清糖原磷酸化酶浓度水平的光亲和标记探针分子、其制备方法及医药用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0021831D0 (en) * 2000-09-06 2000-10-18 Astrazeneca Ab Chemical compounds
US7405210B2 (en) * 2003-05-21 2008-07-29 Osi Pharmaceuticals, Inc. Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase
CA2525502C (en) 2003-05-21 2012-12-18 Prosidion Limited Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase

Also Published As

Publication number Publication date
EP1819704A1 (de) 2007-08-22
DK1819704T3 (da) 2008-10-20
US8664397B2 (en) 2014-03-04
PT1819704E (pt) 2008-10-06
WO2006059165A1 (en) 2006-06-08
EP1819704B1 (de) 2008-07-09
PL1819704T3 (pl) 2008-12-31
US20080293761A1 (en) 2008-11-27
HK1107984A1 (en) 2008-04-25
JP2008521874A (ja) 2008-06-26
ATE400574T1 (de) 2008-07-15
ES2309822T3 (es) 2008-12-16

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