BE905796A - Adn de superoxyde dismutase de manganese humaine, son expression dans les bacteries et procede de recuperation de superoxyde dismutase de manganese humaine. - Google Patents

Adn de superoxyde dismutase de manganese humaine, son expression dans les bacteries et procede de recuperation de superoxyde dismutase de manganese humaine.

Info

Publication number
BE905796A
BE905796A BE0/217445A BE217445A BE905796A BE 905796 A BE905796 A BE 905796A BE 0/217445 A BE0/217445 A BE 0/217445A BE 217445 A BE217445 A BE 217445A BE 905796 A BE905796 A BE 905796A
Authority
BE
Belgium
Prior art keywords
superoxide dismutase
manganese superoxide
human manganese
bacteria
expression
Prior art date
Application number
BE0/217445A
Other languages
English (en)
French (fr)
Original Assignee
Bio Technology General Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Technology General Corp filed Critical Bio Technology General Corp
Publication of BE905796A publication Critical patent/BE905796A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0089Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44Oxidoreductases (1)
    • A61K38/446Superoxide dismutase (1.15)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BE0/217445A 1985-11-22 1986-11-20 Adn de superoxyde dismutase de manganese humaine, son expression dans les bacteries et procede de recuperation de superoxyde dismutase de manganese humaine. BE905796A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80109085A 1985-11-22 1985-11-22
US90705186A 1986-09-12 1986-09-12

Publications (1)

Publication Number Publication Date
BE905796A true BE905796A (fr) 1987-03-16

Family

ID=27122291

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/217445A BE905796A (fr) 1985-11-22 1986-11-20 Adn de superoxyde dismutase de manganese humaine, son expression dans les bacteries et procede de recuperation de superoxyde dismutase de manganese humaine.

Country Status (21)

Country Link
JP (2) JP2609449B2 (fi)
AT (1) AT400443B (fi)
AU (1) AU607897B2 (fi)
BE (1) BE905796A (fi)
CA (1) CA1341362C (fi)
CH (1) CH676990A5 (fi)
DE (1) DE3639725C2 (fi)
DK (1) DK534686A (fi)
ES (1) ES2003518A6 (fi)
FI (1) FI90353C (fi)
FR (1) FR2590591B1 (fi)
GB (1) GB2183658B (fi)
GR (1) GR862713B (fi)
HK (1) HK75195A (fi)
IE (1) IE59498B1 (fi)
IL (2) IL106449A (fi)
IT (1) IT1205418B (fi)
LU (1) LU86676A1 (fi)
NL (1) NL8602960A (fi)
PT (1) PT83792B (fi)
SE (1) SE8604884L (fi)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0284105B1 (en) * 1987-03-27 1995-11-15 Bio-Technology General Corporation Human manganese superoxide dismutase and methods of treatment
EP0282899B1 (de) * 1987-03-14 1996-01-10 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Humane Mangan-Superoxiddismutase (hMn-SOD)
US5540911A (en) * 1985-11-22 1996-07-30 Bio-Technology General Corp. Methods of use of human manganese superoxide dismutase

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62215532A (ja) * 1986-03-18 1987-09-22 Ube Ind Ltd 抗炎症剤
JPH0643341B2 (ja) * 1986-03-27 1994-06-08 宇部興産株式会社 臓器機能改善剤
JPH0643340B2 (ja) * 1986-09-03 1994-06-08 宇部興産株式会社 虚血性心疾患治療薬
JPS6377822A (ja) * 1986-09-18 1988-04-08 Ube Ind Ltd 臓器機能改善剤
US6326003B1 (en) 1986-10-14 2001-12-04 Chiron Corporation Manganese superoxide dismutase cloning and expression in microorganisms
US5260204A (en) * 1987-03-14 1993-11-09 Boehringer Ingelheim International Gmbh Human manganese superoxide dismutase (hMn-SOD)
JPH01233228A (ja) * 1988-03-11 1989-09-19 Toyo Jozo Co Ltd 悪性腫瘍細胞転移防止剤
US5772996A (en) * 1990-08-03 1998-06-30 Public Health Laboratory Service Board Pharmaceutical compositions containing superoxide dismutase from Bacillus Stearothermophilus and Bacillus Caldotenax
DE4038563A1 (de) * 1990-12-04 1992-06-11 Gruenenthal Gmbh Verwendung von superoxiddismutasen zur prophylaxe und/oder behandlung von organversagen bei risikopatienten mit polytrauma
ATE209928T1 (de) * 1992-09-09 2001-12-15 Bio Technology General Corp Verwendung von mangan-superoxiddismutase (mn-sod) zur herstellung von arzneimitteln zur behandlung von erkrankungen in niedriger dosierung
DE4239877C1 (de) * 1992-11-27 1994-03-17 Boehringer Ingelheim Int Stabilisierte Superoxid-Dismutase (SOD)-Zusammensetzung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56102787A (en) * 1980-01-18 1981-08-17 Mamoru Sugiura Preparation of human placenta superoxide dismutase
BG49718A3 (en) * 1983-07-15 1992-01-15 Bio Technology General Corp Method for preparing of polypeptid with superoxiddismutasne activitty
EP0138111B1 (en) * 1983-10-03 1991-11-21 Chiron Corporation Superoxide dismutase cloning and expression in microorganisms

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5540911A (en) * 1985-11-22 1996-07-30 Bio-Technology General Corp. Methods of use of human manganese superoxide dismutase
US6361772B1 (en) 1985-11-22 2002-03-26 Bio-Technology General Corp. Human manganese superoxide dismutase DNA, its expression and method of recovering human manganese superoxide dismutase
US6610520B1 (en) 1985-11-22 2003-08-26 Bio-Technology General Corp. Gene encoding human manganese superoxide dismutase and recombinant polypeptide encoded thereby
EP0282899B1 (de) * 1987-03-14 1996-01-10 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Humane Mangan-Superoxiddismutase (hMn-SOD)
EP0284105B1 (en) * 1987-03-27 1995-11-15 Bio-Technology General Corporation Human manganese superoxide dismutase and methods of treatment

Also Published As

Publication number Publication date
IL106449A0 (en) 1993-11-15
JP2609449B2 (ja) 1997-05-14
CA1341362C (en) 2002-05-28
ATA308986A (de) 1995-05-15
PT83792B (pt) 1989-01-17
IE59498B1 (en) 1994-03-09
IT1205418B (it) 1989-03-15
FI864756A0 (fi) 1986-11-21
SE8604884L (sv) 1987-05-23
IL80702A0 (en) 1987-02-27
HK75195A (en) 1995-05-26
JPH08289792A (ja) 1996-11-05
SE8604884D0 (sv) 1986-11-14
GR862713B (en) 1987-03-24
FI90353B (fi) 1993-10-15
FR2590591A1 (fr) 1987-05-29
LU86676A1 (fr) 1987-05-04
DK534686D0 (da) 1986-11-07
FI90353C (fi) 1994-01-25
JP2967557B2 (ja) 1999-10-25
GB8627294D0 (en) 1986-12-17
AT400443B (de) 1995-12-27
IL106449A (en) 1997-02-18
FR2590591B1 (fr) 1989-12-01
IT8667865A0 (it) 1986-11-21
GB2183658B (en) 1990-04-25
AU6497586A (en) 1987-05-28
ES2003518A6 (es) 1988-11-01
NL8602960A (nl) 1987-06-16
FI864756A (fi) 1987-05-23
AU607897B2 (en) 1991-03-21
DE3639725A1 (de) 1987-07-23
PT83792A (en) 1986-12-01
DK534686A (da) 1987-05-23
GB2183658A (en) 1987-06-10
IE862851L (en) 1987-05-22
CH676990A5 (fi) 1991-03-28
JPS62289187A (ja) 1987-12-16
DE3639725C2 (de) 1998-02-19

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: *BIO-TECHNOLOGY GENERAL CORP.

Effective date: 20021130