BA97150B1 - Postupak za dobivanje derivata cis-4-fenil-1,2,3,4-tetrahidro-1--naftalinamina - Google Patents

Postupak za dobivanje derivata cis-4-fenil-1,2,3,4-tetrahidro-1--naftalinamina

Info

Publication number
BA97150B1
BA97150B1 BA970150A BA970150A BA97150B1 BA 97150 B1 BA97150 B1 BA 97150B1 BA 970150 A BA970150 A BA 970150A BA 970150 A BA970150 A BA 970150A BA 97150 B1 BA97150 B1 BA 97150B1
Authority
BA
Bosnia and Herzegovina
Prior art keywords
tetrahydro
cis
phenyl
naphthalinamine
derivative
Prior art date
Application number
BA970150A
Other languages
Bosnian (bs)
English (en)
Inventor
Willard Mcknowan Welch
Charles Armon Harbert
Billie Kenneth Koe
Allen Richard Kraska
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22221931&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BA97150(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Priority to BA970150A priority Critical patent/BA97150B1/bs
Application granted granted Critical
Publication of BA97150B1 publication Critical patent/BA97150B1/bs

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/04Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
    • C07C209/14Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of hydroxy groups or of etherified or esterified hydroxy groups
    • C07C209/16Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of hydroxy groups or of etherified or esterified hydroxy groups with formation of amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/21Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing rings other than six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/30Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/28Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of CHx-moieties
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C07C57/60Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BA970150A 1979-11-01 1997-03-28 Postupak za dobivanje derivata cis-4-fenil-1,2,3,4-tetrahidro-1--naftalinamina BA97150B1 (bs)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BA970150A BA97150B1 (bs) 1979-11-01 1997-03-28 Postupak za dobivanje derivata cis-4-fenil-1,2,3,4-tetrahidro-1--naftalinamina

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US06/090,240 US4536518A (en) 1979-11-01 1979-11-01 Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
YU2798/80A YU41951B (en) 1979-11-01 1980-10-31 Process for obtaining cis-4-phenyl01,2,3,4-tetrahydro-1-naphthaleneamine
YU672/83A YU42846B (en) 1979-11-01 1983-03-21 Process for obtaining derivatives of cis-4-phenyl-1,2,3,4 tetrahydro-1-naphtalynamines
BA970150A BA97150B1 (bs) 1979-11-01 1997-03-28 Postupak za dobivanje derivata cis-4-fenil-1,2,3,4-tetrahidro-1--naftalinamina
BA970149A BA97149B1 (bs) 1979-11-01 1997-03-28 Postupak za dobivanje cis-4-fenil-1,2,3,4-tetrahidro-1-naftalinamina

Publications (1)

Publication Number Publication Date
BA97150B1 true BA97150B1 (bs) 1998-12-28

Family

ID=22221931

Family Applications (2)

Application Number Title Priority Date Filing Date
BA970150A BA97150B1 (bs) 1979-11-01 1997-03-28 Postupak za dobivanje derivata cis-4-fenil-1,2,3,4-tetrahidro-1--naftalinamina
BA970149A BA97149B1 (bs) 1979-11-01 1997-03-28 Postupak za dobivanje cis-4-fenil-1,2,3,4-tetrahidro-1-naftalinamina

Family Applications After (1)

Application Number Title Priority Date Filing Date
BA970149A BA97149B1 (bs) 1979-11-01 1997-03-28 Postupak za dobivanje cis-4-fenil-1,2,3,4-tetrahidro-1-naftalinamina

Country Status (38)

Country Link
US (1) US4536518A (fr)
EP (1) EP0030081B1 (fr)
JP (1) JPS605584B2 (fr)
KR (2) KR840002001B1 (fr)
AT (1) ATE2668T1 (fr)
AU (1) AU517357B2 (fr)
BA (2) BA97150B1 (fr)
BG (1) BG60333B2 (fr)
CA (1) CA1130815A (fr)
CS (4) CS238609B2 (fr)
DD (2) DD155615A5 (fr)
DE (2) DE3062225D1 (fr)
DK (1) DK153390C (fr)
EG (1) EG15527A (fr)
ES (2) ES8201949A1 (fr)
FI (1) FI68806C (fr)
GR (1) GR70781B (fr)
HK (1) HK82284A (fr)
HR (2) HRP930199B1 (fr)
HU (1) HU182224B (fr)
IE (1) IE50395B1 (fr)
IL (1) IL61374A (fr)
IN (2) IN159643B (fr)
LU (1) LU88330I2 (fr)
LV (2) LV5456A3 (fr)
MX (1) MX5980E (fr)
MY (1) MY8500326A (fr)
NL (1) NL940018I1 (fr)
NO (2) NO148996C (fr)
NZ (1) NZ195407A (fr)
PH (1) PH17319A (fr)
PT (1) PT72004B (fr)
SG (1) SG56584G (fr)
SI (2) SI8012798A8 (fr)
SU (2) SU1014467A3 (fr)
UA (2) UA6311A1 (fr)
YU (2) YU41951B (fr)
ZA (1) ZA806726B (fr)

Families Citing this family (171)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
US4839104A (en) * 1987-06-11 1989-06-13 Pfizer, Inc. Process for preparing sertraline intermediates
US4777288A (en) * 1987-06-11 1988-10-11 Pfizer Inc. Process for preparing a 4,4-diphenylbutanoic acid derivative
FR2623802B1 (fr) * 1987-11-26 1990-05-04 Lucien Laboratoires Derives d'amino-4 trifluoromethyl-1 tetralines. leur preparation et leur application en therapeutique
US4855500A (en) * 1988-05-04 1989-08-08 Pfizer Inc. Process for preparing a ketimine
FR2632633B1 (fr) * 1988-06-08 1991-04-05 Delalande Sa Procede de preparation de 4-aryl-1-tetralones
US4981870A (en) * 1989-03-07 1991-01-01 Pfizer Inc. Use of 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine derivatives in the treatment of psychosis, inflammation and as immunosuppressants
US4940731A (en) * 1989-08-30 1990-07-10 Pfizer Inc. Method of treating premature ejaculation using sertraline
DE69004529T2 (de) * 1989-08-30 1994-02-24 Pfizer Verwendung von Sertralin zur Behandlung von Abhängigkeiten von chemischen Stoffen.
US5130338A (en) * 1989-08-30 1992-07-14 Pfizer Inc. Method of treating chemical dependencies using sertraline
US4962128A (en) * 1989-11-02 1990-10-09 Pfizer Inc. Method of treating anxiety-related disorders using sertraline
FR2665443B1 (fr) * 1990-08-03 1992-11-06 Lucien Laboratoires Derives d'amino-4-methyl-1-tetralines, leur preparation et leur application en therapeutique.
US5082970A (en) * 1991-03-06 1992-01-21 Pfizer Inc. Process for recycling amine isomer
GB9114947D0 (en) * 1991-07-11 1991-08-28 Pfizer Ltd Process for preparing sertraline
GB9114948D0 (en) * 1991-07-11 1991-08-28 Pfizer Ltd Process for preparing sertraline intermediates
US5196607A (en) * 1992-02-14 1993-03-23 Pfizer Inc. Process for preparing ketone enantiomer
US5248699A (en) * 1992-08-13 1993-09-28 Pfizer Inc. Sertraline polymorph
US5288916A (en) 1993-03-25 1994-02-22 Bend Research, Inc. Enantiomeric resolution of 4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone
DE69406553T2 (de) * 1993-11-30 1998-02-26 Pfizer Inc., New York, N.Y. Verfahren zur herstellung von chiralen tetralonen
US5597826A (en) 1994-09-14 1997-01-28 Pfizer Inc. Compositions containing sertraline and a 5-HT1D receptor agonist or antagonist
US6410794B1 (en) 1994-12-16 2002-06-25 Uop Llc Process for preparation of pharmaceutically desired chiral tetralone from tetralones
US6455736B1 (en) 1994-12-16 2002-09-24 Uop Llc Process for preparation of pharmaceutically desired sertraline and sertraline analogs
AU5966196A (en) * 1995-06-08 1997-01-09 Eli Lilly And Company Methods of treating cold and allergic rhinitis
US6548084B2 (en) * 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
ATE192042T1 (de) * 1995-08-16 2000-05-15 Lilly Co Eli Potenzierung von serotonin-wirkstoffresponz
US5734083A (en) * 1996-05-17 1998-03-31 Torcan Chemical Ltd. Sertraline polymorph
HU222341B1 (hu) * 1996-12-18 2003-06-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás sertralin előállítására és az eljárásban alkalmazott intermedier
TW526195B (en) * 1997-06-10 2003-04-01 Novartis Ag Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use
US20040208926A1 (en) * 1997-07-01 2004-10-21 Pfizer Inc Solubilized sertraline compositions
US20030133974A1 (en) * 1997-07-01 2003-07-17 Curatolo William John Encapsulated solution dosage forms of sertraline
JP2000514101A (ja) 1997-07-01 2000-10-24 ファイザー・インク セルトラリン塩及びセルトラリンの持続性剤形
EP0928784B1 (fr) * 1997-12-11 2002-06-12 TORCAN CHEMICAL Ltd Sertraline polymorphe ayant une hydrosolubilité améliorée
IN191358B (fr) 1998-01-16 2003-11-29 Pfizer Prod Inc
WO1999046233A1 (fr) * 1998-03-09 1999-09-16 Sumika Fine Chemicals Co., Ltd. Derives de l'alcool benzylique
AR018164A1 (es) * 1998-03-18 2001-10-31 Ciba Sc Holding Ag Proceso para la preparacion de cis-ciclohexilidenaminas
FR2777000B1 (fr) * 1998-04-01 2002-09-27 Catalys Procede de preparation de la sertraline racemique
PT957099E (pt) 1998-04-15 2003-02-28 Pfizer Prod Inc Carboxamidas heterociclicas
US6054614A (en) * 1998-04-23 2000-04-25 Ciba Specialty Chemicals Corporation Process for the preparation of tetralone imines for the preparation of active pharmaceutical compounds
HU226423B1 (en) * 1998-05-05 2008-12-29 Egis Gyogyszergyar Nyrt Process for producing a 1(2h)-naphtalene-1-ylidene derivative
HU226424B1 (en) * 1998-05-05 2008-12-29 Egis Gyogyszergyar Nyrt Process for producing enantiomer mixture for preparation of sertraline
IN182588B (fr) * 1998-05-12 1999-05-08 Sun Pharmaceutical Ind Ltd
DE19830201A1 (de) * 1998-07-07 2000-01-13 Boehringer Ingelheim Pharma Mittel mit antidepressiver Wirkung
US6727283B2 (en) 1998-10-13 2004-04-27 Pfizer Inc. Sertraline oral concentrate
JP3792514B2 (ja) * 1998-10-13 2006-07-05 ファイザー・プロダクツ・インク セルトラリン経口濃縮物
IL132500A0 (en) 1998-10-29 2001-03-19 Pfizer Prod Inc Stereoselective microbial reduction of a racemic tetralone
AU1031500A (en) * 1998-11-03 2000-05-22 Dandy A/S Sucrose fatty acid esters for use as increased release of active ingredients
US6518284B2 (en) * 1998-11-18 2003-02-11 Faes, Fabrica Espanola De Productos Quimicos Y Farmaceuticos S.A. 4-substituted piperidines
US6500987B1 (en) * 1998-11-27 2002-12-31 Teva Pharmaceutical Industries Ltd. Sertraline hydrochloride polymorphs
EP1632472A1 (fr) * 1998-11-27 2006-03-08 Teva Pharmaceutical Industries Ltd Polymorphes de chlorhydrate de Sertraline
IL143311A0 (en) * 1998-11-27 2002-04-21 Teva Pharma Sertraline hydrochloride polymorphs
WO2000051972A1 (fr) * 1999-03-01 2000-09-08 Pfizer Limited Composes 1,2,3,4-tetrahydro-1-naphthalenamines utiles en therapie
US6245782B1 (en) 1999-05-17 2001-06-12 Heartdrug Research L.L.C. Methods of inhibiting platelet activation with selective serotonin reuptake inhibitors
US6593496B1 (en) 1999-06-09 2003-07-15 Pfizer Inc Process for preparing sertraline from chiral tetralone
EP1200387B1 (fr) * 1999-07-29 2004-04-21 Ciba SC Holding AG Procede d'hydrogenation catalytique cis-selective de cyclohexylidenamines
US6495721B1 (en) 1999-08-09 2002-12-17 Teva Pharmaceutical Industries Ltd. Sertraline hydrochloride Form II and methods for the preparation thereof
IN185109B (fr) * 1999-09-01 2000-11-18 Torrent Pharmaceuticals Ltd
DK174219B1 (da) * 1999-10-27 2002-09-30 Gea Farmaceutisk Fabrik As Forbedret syntese af racemisk sertralin
TWI260315B (en) * 1999-10-29 2006-08-21 Ciba Sc Holding Ag Polymorphic forms of sertraline hydrochloride
US20050119351A1 (en) * 1999-10-29 2005-06-02 Van Der Schaaf Paul A. Polymorphic forms of sertraline hydrochloride
US7442838B2 (en) * 1999-10-29 2008-10-28 Ciba Specialty Chemicals Corp. Polymorphic forms of sertraline hydrochloride
ES2241680T3 (es) * 1999-11-16 2005-11-01 Ciba Specialty Chemicals Holding Inc. Procedimiento para la preparacion de cetiminas.
MXPA02004854A (es) 1999-11-16 2002-08-30 Ciba Sc Holding Ag Proceso para la preparacion de cetiminas.
US6380200B1 (en) 1999-12-07 2002-04-30 Pfizer, Inc. Combination of aldose reductase inhibitors and selective serotonin reuptake inhibitors for the treatment of diabetic complications
PT1248605E (pt) * 1999-12-21 2007-03-30 Teva Pharma Novos polimorfos de cloridrato de sertralina, processos para a sua preparação, composições que os contêm e métodos para a sua utilização
JP2003518487A (ja) 1999-12-23 2003-06-10 ファイザー・プロダクツ・インク ヒドロゲル駆動型積層薬物製剤
IN187170B (fr) 2000-01-04 2002-02-23 Sun Pharmaceutical Ind Ltd
HUP0300160A3 (en) * 2000-03-14 2005-07-28 Teva Pharma Process for preparing (+)-cis-sertraline
EP1284729A4 (fr) * 2000-04-13 2007-12-19 Mayo Foundation Agents de reduction de a(beta)42
IN192343B (fr) * 2000-05-26 2004-04-10 Ranbaxy Lab Ltd
US6630504B2 (en) 2000-08-31 2003-10-07 Pfizer Inc. Phenoxyphenylheterocyclyl derivatives as SSRIs
EP1184372B1 (fr) * 2000-08-31 2006-04-26 Pfizer Limited Dérivés hétérocycliques de phénoxyphényl, inhibiteurs de réabsorption de sérotonine
US6482440B2 (en) 2000-09-21 2002-11-19 Phase 2 Discovery, Inc. Long acting antidepressant microparticles
US6645946B1 (en) 2001-03-27 2003-11-11 Pro-Pharmaceuticals, Inc. Delivery of a therapeutic agent in a formulation for reduced toxicity
CA2448279A1 (fr) * 2001-05-31 2002-12-05 Orion Corporation Fermion Procede de fabrication de chlorhydrate de sertraline polymorphe de forme ii
US6723878B2 (en) 2001-06-15 2004-04-20 Orion Corporation Fermion Method for preparing sertraline
CA2448499A1 (fr) * 2001-06-15 2002-12-27 Orion Corporation Fermion Nouveau procede pour la preparation de (is-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-naphtalenamine
EP1434763B1 (fr) * 2001-10-12 2018-01-17 Azevan Pharmaceuticals, Inc. Antagonistes v1a de vasopressine beta-lactamyl
AU2003217676B2 (en) 2002-02-22 2009-06-11 Takeda Pharmaceutical Company Limited Active agent delivery systems and methods for protecting and administering active agents
AU2003251290A1 (en) * 2002-04-29 2003-11-17 Teva Pharmaceutical Industries Ltd. Process for preparation of polymorphic form ii of sertraline hydrochloride, pharmaceutical formulations and methods of administration thereof
WO2004011413A1 (fr) * 2002-07-29 2004-02-05 Cipla Limited Sertraline
PL376832A1 (pl) * 2002-11-07 2006-01-09 Torrent Pharmaceuticals Ltd. Sposób wytwarzania polimorficznej postaci chlorowodorku sertraliny
US20040131672A1 (en) * 2003-01-07 2004-07-08 Nilobon Podhipleux Direct compression pharmaceutical composition containing a pharmaceutically active ingredient with poor flowing properties
EP1603548A4 (fr) * 2003-02-05 2007-10-10 Myriad Genetics Inc Composition et methode de traitement de troubles neurodegeneratifs
WO2004087732A2 (fr) * 2003-03-11 2004-10-14 Sun Pharmaceutical Industries Limited Procede de preparation de (1s, 4s)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-naphtylamine
ES2242555T1 (es) * 2003-04-14 2005-11-16 Teva Pharmaceutical Industries Limited Hidrogenacion de intermediarios de imina de sertralina con catalizadores.
EP1626950A4 (fr) * 2003-05-23 2007-05-23 Transform Pharmaceuticals Inc Compositions de sertraline
US20050070577A1 (en) * 2003-07-03 2005-03-31 Pfizer Inc. Compositions containing a serotonin selective reuptake inhibitor and a 5-HT2A receptor antagonist
EP1651195A4 (fr) * 2003-07-11 2007-10-03 Myriad Genetics Inc Procedes pharmaceutiques, posologies et formes posologiques pour le traitement de la maladie d'alzheimer
WO2005012224A1 (fr) * 2003-07-15 2005-02-10 Recordati Industria Chimica E Farmaceutica S.P.A. Chlorhydrate de sertraline de forme ii et procedes de preparation associes
US7189876B2 (en) * 2003-07-15 2007-03-13 Recordati Industria Chimica E Farmaceutica S.P.A. Methods for preparing sertraline hydrochloride polymorphs
HU227495B1 (en) * 2003-07-21 2011-07-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Process for producing of imine intermediate
WO2005023752A2 (fr) * 2003-09-05 2005-03-17 Teva Pharmaceutical Industries Ltd. Procede de recyclage pour l'elaboration de sertraline
WO2005025563A1 (fr) * 2003-09-12 2005-03-24 Warner-Lambert Company Llc Combinaison comportant un ligand alpha-2-delta et un inhibiteur selectif du recaptage de la serotonine et/ou un inhibiteur selectif du recaptage de la noradrenaline et permettant le traitement de la depression et des troubles anxieux
CA2537402C (fr) 2003-09-12 2009-05-05 Pfizer Inc. Associations comprenant des ligands alpha-2-delta et des inhibiteurs du recaptage de la serotonine et de la noradrenaline
CN103788089A (zh) * 2003-09-17 2014-05-14 詹森药业有限公司 作为血清素受体调节剂的稠合杂环化合物
RU2376279C2 (ru) * 2003-11-04 2009-12-20 Сипла Лимитед Способ получения полиморфов ингибитора повторного захвата серотонина (варианты)
US20050250803A1 (en) * 2003-11-26 2005-11-10 Pfizer Inc Combination of dopamine agonists and monoamine reuptake inhibitors
CA2547283C (fr) * 2003-11-26 2010-11-09 Pfizer Products Inc. Derives d'aminopyrazole en tant qu'inhibiteurs de la gsk-3
WO2005060968A1 (fr) 2003-12-11 2005-07-07 Sepracor Inc. Combinaison d'un sedatif et d'un modulateur des neurotransmetteurs, et methodes permettant d'ameliorer la qualite du sommeil et de traiter la depression
WO2006001877A2 (fr) * 2004-04-13 2006-01-05 Myriad Genetics, Inc. Composition pharmaceutique et methode de traitement de troubles neurodegeneratifs
EP1737473A4 (fr) * 2004-04-19 2009-08-26 Noven Therapeutics Llc Combinaisons de lithium et utilisations associees
WO2005117911A2 (fr) * 2004-05-06 2005-12-15 Cydex, Inc. Preparations au gout masque contenant de la sertraline et de la sulfoalkylether cyclodextrine
AR049401A1 (es) 2004-06-18 2006-07-26 Novartis Ag Aza-biciclononanos
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
WO2006020852A2 (fr) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Composition pharmaceutique et technique de traitement de troubles neurodegeneratifs
WO2006020850A2 (fr) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Composition pharmaceutique et technique de traitement de troubles neurodegeneratifs
BRPI0514303A (pt) * 2004-08-11 2008-06-10 Myriad Genetics Inc composição farmacêutica e método para tratar distúrbios neurodegenerativos
US7345201B2 (en) * 2005-02-23 2008-03-18 Teva Pharmaceutical Industries, Ltd. Processes for preparing sertraline
AU2006227199A1 (en) 2005-03-22 2006-09-28 Azevan Pharmaceuticals, Inc. Beta-lactamylalkanoic acids for treating premenstrual disorders
JP2006265169A (ja) * 2005-03-24 2006-10-05 Tokuyama Corp アルキリデンコハク酸化合物の製造方法
GB0507090D0 (en) * 2005-04-07 2005-05-11 Sandoz Ag Process for preparing polymorphic form ll of sertraline hydrochloride
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
GT200600165A (es) * 2005-04-22 2007-03-14 Derivados dihidrobenzofuranos y usos de los mismos
PE20061297A1 (es) * 2005-04-22 2006-12-24 Wyeth Corp Compuestos derivados de cromano y cromeno moduladores del receptor de serotonina 5-ht2c
MX2007012883A (es) 2005-04-22 2007-12-10 Wyeth Corp Derivados de dihidrobenzofurano y usos de los mismos.
US20060252825A1 (en) * 2005-04-22 2006-11-09 Wyeth Crystal forms of {[(2r)-7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-benzofuran-2-yl]methyl}amine hydrochloride
BRPI0610036A2 (pt) 2005-04-22 2010-05-18 Wyeth Corp derivados de benzofuranil alcanamina e usos destes como agonìstico de 5-ht2c
US20070260090A1 (en) * 2005-06-03 2007-11-08 Hetero Drugs Limited Highly Steroselective Synthesis of Sertraline
WO2007008317A2 (fr) * 2005-06-09 2007-01-18 Teva Pharmaceutical Industries Ltd. Procede de preparation de la forme i de chlorhydrate de sertraline
EP1896002A4 (fr) * 2005-06-27 2009-11-25 Biovail Lab Int Srl Formulations a liberation modifiee d'un sel de bupropion
AU2006269231A1 (en) 2005-07-08 2007-01-18 Braincells, Inc. Methods for identifying agents and conditions that modulate neurogenesis
US20070015832A1 (en) * 2005-07-14 2007-01-18 Myriad Genetics, Incorporated Methods of treating overactive bladder and urinary incontinence
JP5328349B2 (ja) * 2005-07-19 2013-10-30 アゼヴァン ファーマスーティカルズ,インコーポレイテッド ベータ−ラクタミルフェニルアラニン、システイン、およびセリン・バソプレッシン拮抗剤
US7598255B2 (en) * 2005-08-04 2009-10-06 Janssen Pharmaceutica Nv Pyrimidine compounds as serotonin receptor modulators
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
GB0525673D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
GB0525672D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
CN101426372A (zh) * 2006-01-06 2009-05-06 塞普拉柯公司 基于四氢萘酮的单胺再摄取抑制剂
WO2007087387A1 (fr) * 2006-01-23 2007-08-02 Teva Pharmaceutical Industries Ltd. Procede de recyclage pour preparer la sertraline
FR2912057B1 (fr) * 2007-02-07 2009-04-17 Sanofi Aventis Sa Composition pharmaceutique contenant en association le saredutant et un inhibiteur selectif de la recapture de la serotonine ou un inhibiteur de la recapture de la serotonine/norepinephrine
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
AU2007231011A1 (en) * 2006-03-24 2007-10-04 Wyeth New therapeutic combinations for the treatment of depression
WO2007119247A2 (fr) * 2006-04-17 2007-10-25 Unichem Laboratories Limited Procédé de production amélioré destiné à la préparation de la forme polymorphe ii de l'hydrochlorure de cis-(1s)-n-methyl-4-(3,4-dichlorophényle)-1,2,3,4-tétrahydro-1-napthlèneamine (hydrochlorure de sertraline)
TR200808115T1 (tr) * 2006-04-28 2009-03-23 Sandoz Ag 4(S,R)-(3,4-diklorofenil)-3,4-dihidro-l(2H)-naftalin-l-ilid n]metilamin'ın Hazırlanması için Proses.@
EP2026813A2 (fr) 2006-05-09 2009-02-25 Braincells, Inc. Neurogenèse induite par le récepteur 5ht
EP2021000A2 (fr) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenèse par modulation de l'angiotensine
US7858611B2 (en) * 2006-05-09 2010-12-28 Braincells Inc. Neurogenesis by modulating angiotensin
US7518019B2 (en) * 2006-06-01 2009-04-14 Hetero Drugs Limited Processes for preparing sertraline hydrochloride crystalline forms
WO2007146796A2 (fr) * 2006-06-13 2007-12-21 Ramot At Tel-Aviv University Ltd. Composés antiprolifératifs, compositions contenant ceux-ci et procédés d'utilisation de ceux-ci
US7893053B2 (en) * 2006-06-16 2011-02-22 Theracos, Inc. Treating psychological conditions using muscarinic receptor M1 antagonists
EP2046119A2 (fr) * 2006-07-07 2009-04-15 Myriad Genetics, Inc. Traitement de troubles psychiatriques
TW200817003A (en) * 2006-07-31 2008-04-16 Sanofi Aventis Pharmaceutical composition comprising, in combination, saredutant and a selective serotonin peuptake inhibitor or a serotonin/norepinephrine reuptake inhibitor
US20060257475A1 (en) * 2006-08-17 2006-11-16 Boehringer Ingelheim International Gmbh Stable Sertraline Hydrochloride Formulation and Method
JP2010502722A (ja) 2006-09-08 2010-01-28 ブレインセルス,インコーポレイティド 4−アシルアミノピリジン誘導体を含む組み合わせ
US20100016274A1 (en) * 2006-09-14 2010-01-21 Koppel Gary A Beta-lactam cannabinoid receptor modulators
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
FR2909376A1 (fr) * 2006-11-30 2008-06-06 Cerep Sa Procedes de preparation de la desmethulsertraline ou d'un de ses sels pharmaceutiquement acceptables
US20080167363A1 (en) * 2006-12-28 2008-07-10 Braincells, Inc Modulation of Neurogenesis By Melatoninergic Agents
US20080171750A1 (en) * 2007-01-11 2008-07-17 Braincells, Inc. Modulation Of Neurogenesis With Use of Modafinil
CA2594198A1 (fr) * 2007-07-20 2009-01-20 Apotex Pharmachem Inc. Procede inedit de preparation d'hydrochlorure de sertraline de forme ii
US20090062399A1 (en) * 2007-08-29 2009-03-05 Protia, Llc Deuterium-enriched sertraline
EP2288345B1 (fr) 2008-04-18 2015-06-10 University College Dublin National University Of Ireland, Dublin Produits psycho-pharmaceutiques
EP2291181B9 (fr) 2008-04-18 2013-09-11 University College Dublin National University Of Ireland, Dublin Utilisation de la captodiamine pour le traitement des symptômes de la dépression
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
US9260413B2 (en) * 2010-03-04 2016-02-16 Merck Sharp & Dohme Corp. Inhibitors of catechol O-methyl transferase and their use in the treatment of psychotic disorders
EP2380595A1 (fr) 2010-04-19 2011-10-26 Nlife Therapeutics S.L. Compositions et procédés pour la fourniture sélective de molécules d'oligonucléotides à des types de neurones spécifiques
US8440655B2 (en) 2010-06-21 2013-05-14 Theracos, Inc. Combination therapy for the treatment of diabetes
RU2623209C9 (ru) 2010-07-01 2018-01-22 Азеван Фармасьютикалз, Инк. Способы лечения посттравматического стрессового расстройства
JP2014508187A (ja) 2011-03-17 2014-04-03 ルピン・リミテッド 選択的セロトニン再取り込み阻害薬の放出制御医薬組成物
KR101340270B1 (ko) * 2011-11-10 2013-12-10 보령제약 주식회사 (+)-시스-서트랄린의 선택적인 제조방법
KR20150070102A (ko) * 2012-10-18 2015-06-24 에프. 호프만-라 로슈 아게 mGluR5 수용체 활성의 조절제로서 에틴일 유도체
RU2742773C2 (ru) 2014-03-28 2021-02-10 Азеван Фармасьютикалз, Инк. Композиции и способы лечения нейродегенеративных заболеваний
US10266481B2 (en) 2014-06-20 2019-04-23 Council Of Scientific & Industrial Research Organocatalytic asymmetric synthesis of antidepressants
EP3180337B1 (fr) * 2014-08-11 2018-10-10 Hydra Biosciences, Inc. Dérivés de pyrido[3,4-d]pyrimidine-2,4(1h,3h)-dione
JP6667092B2 (ja) * 2014-08-11 2020-03-18 ハイドラ・バイオサイエンシーズ・リミテッド・ライアビリティ・カンパニーHydra Biosciences, LLC ピロロ[3,2−d]ピリミジン−2,4(3H,5H)−ジオン誘導体
EP3180340B1 (fr) * 2014-08-11 2018-10-10 Hydra Biosciences, Inc. Dérivés de pyrido[2,3-d]pyrimidine-2,4(1h,3h)-dione
EP3180345B1 (fr) * 2014-08-11 2018-10-10 Hydra Biosciences, Inc. Dérivés thieno- et furo[2,3-d]pyrimidine-2,4[1h,3h]-dione en tant que modulateurs trpc5 pour le traitement de maladies neuropsychiatriques
JP7405341B2 (ja) 2015-09-21 2023-12-26 エス.シー. ジョンソン アンド サン、インコーポレイテッド 混合及び散布のシステム
AU2018333051B2 (en) 2017-09-15 2024-03-21 Azevan Pharmaceuticals, Inc. Compositions and methods for treating brain injury
WO2020043716A1 (fr) 2018-08-27 2020-03-05 Katholieke Universiteit Leuven Ciblage pharmacologique de la synthèse de novo de sérine/glycine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2887509A (en) * 1956-11-05 1959-05-19 Lilly Co Eli Hydroxybenzoyl benzoate salt of beta-(o-chlorophenyl)-beta-hydroxyethyl isopropylamine
US3704323A (en) * 1969-12-23 1972-11-28 Squibb & Sons Inc Indane derivatives
US4029731A (en) * 1974-11-06 1977-06-14 Pfizer Inc. Aminophenyltetralin compounds
US4045488A (en) * 1974-11-06 1977-08-30 Pfizer Inc. Aminophenyltetralin compounds

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