AU2019251356B2 - Oncolytic adenovirus compositions with enhanced replication properties - Google Patents

Oncolytic adenovirus compositions with enhanced replication properties Download PDF

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AU2019251356B2
AU2019251356B2 AU2019251356A AU2019251356A AU2019251356B2 AU 2019251356 B2 AU2019251356 B2 AU 2019251356B2 AU 2019251356 A AU2019251356 A AU 2019251356A AU 2019251356 A AU2019251356 A AU 2019251356A AU 2019251356 B2 AU2019251356 B2 AU 2019251356B2
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seq
recombinant adenovirus
adsyn
genome
adenovirus genome
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AU2019251356A1 (en
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Michael LYMAN
Shigeki MIYAKE-STONER
Clodagh O'shea
William Partlo
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Salk Institute for Biological Studies
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    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
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    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10371—Demonstrated in vivo effect
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AU2019251356A 2018-04-09 2019-04-09 Oncolytic adenovirus compositions with enhanced replication properties Active AU2019251356B2 (en)

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US201862655009P 2018-04-09 2018-04-09
US62/655,009 2018-04-09
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EP (1) EP3775175A4 (enExample)
JP (2) JP7430395B2 (enExample)
KR (1) KR20200140848A (enExample)
CN (1) CN112292449A (enExample)
AU (2) AU2019251356B2 (enExample)
BR (1) BR112020019942A2 (enExample)
CA (1) CA3096099A1 (enExample)
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Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
SG11201507393TA (en) 2013-03-14 2015-10-29 Salk Inst For Biological Studi Oncolytic adenovirus compositions
ES2899913T3 (es) 2014-09-24 2022-03-15 Salk Inst For Biological Studi Virus tumorales oncolíticos y métodos de uso
WO2017147265A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
EP3390645B1 (en) 2016-02-23 2022-09-14 Salk Institute for Biological Studies Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
AU2017375633C1 (en) 2016-12-12 2023-04-27 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
BR112020019942A2 (pt) * 2018-04-09 2021-01-26 Salk Institute For Biological Studies composições de adenovírus oncolítico com propriedades de replicação aprimoradas
EP4133090A1 (en) 2020-04-07 2023-02-15 Lung Biotechnology PBC Adenoviral expression vector and methods and cell lines for production
WO2022010946A1 (en) * 2020-07-06 2022-01-13 Salk Institute For Biological Studies Oncolytic adenovirus with replication selectivity based on status of p53 transcriptional activity
CN114213505B (zh) * 2021-12-10 2022-09-20 和元生物技术（上海）股份有限公司 一种适用于特异感染u87-mg细胞的腺相关病毒突变体

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