AU2014212004B2 - Compositions for treating or preventing or reducing the severity of clostridium difficile related diseases - Google Patents

Compositions for treating or preventing or reducing the severity of clostridium difficile related diseases Download PDF

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Publication number
AU2014212004B2
AU2014212004B2 AU2014212004A AU2014212004A AU2014212004B2 AU 2014212004 B2 AU2014212004 B2 AU 2014212004B2 AU 2014212004 A AU2014212004 A AU 2014212004A AU 2014212004 A AU2014212004 A AU 2014212004A AU 2014212004 B2 AU2014212004 B2 AU 2014212004B2
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Australia
Prior art keywords
dna
page
sequence listing
spore
bacterial
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AU2014212004A1 (en
Inventor
John G. Aunins
David A. Berry
David Cook
Brian Goodman
Matthew R. HENN
Gregory Mckenzie
Mary-Jane Lombardo Mckenzie
Geoffrey Von Maltzahn
Marin VULIC
Jonathan WINKLER
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Societe des Produits Nestle SA
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Societe des Produits Nestle SA
Nestle SA
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Publication of AU2014212004B2 publication Critical patent/AU2014212004B2/en
Priority to AU2018282348A priority Critical patent/AU2018282348A1/en
Priority to AU2020260564A priority patent/AU2020260564A1/en
Priority to AU2024202421A priority patent/AU2024202421A1/en
Assigned to Société des Produits Nestlé S.A. reassignment Société des Produits Nestlé S.A. Request for Assignment Assignors: SERES THERAPEUTICS, INC.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2014212004A 2013-02-04 2014-02-04 Compositions for treating or preventing or reducing the severity of clostridium difficile related diseases Active AU2014212004B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2018282348A AU2018282348A1 (en) 2013-02-04 2018-12-19 Compositions and methods
AU2020260564A AU2020260564A1 (en) 2013-02-04 2020-10-30 Compositions and methods
AU2024202421A AU2024202421A1 (en) 2013-02-04 2024-04-12 Compositions and methods

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201361760584P 2013-02-04 2013-02-04
US201361760606P 2013-02-04 2013-02-04
US201361760585P 2013-02-04 2013-02-04
US201361760574P 2013-02-04 2013-02-04
US61/760,606 2013-02-04
US61/760,584 2013-02-04
US61/760,574 2013-02-04
US61/760,585 2013-02-04
US201461926918P 2014-01-13 2014-01-13
US61/926,918 2014-01-13
PCT/US2014/014745 WO2014121302A2 (en) 2013-02-04 2014-02-04 Compositions and methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2018282348A Division AU2018282348A1 (en) 2013-02-04 2018-12-19 Compositions and methods

Publications (2)

Publication Number Publication Date
AU2014212004A1 AU2014212004A1 (en) 2015-09-24
AU2014212004B2 true AU2014212004B2 (en) 2018-09-20

Family

ID=51263061

Family Applications (7)

Application Number Title Priority Date Filing Date
AU2014212004A Active AU2014212004B2 (en) 2013-02-04 2014-02-04 Compositions for treating or preventing or reducing the severity of clostridium difficile related diseases
AU2014212003A Active AU2014212003C1 (en) 2013-02-04 2014-02-04 Compositions and methods for inhibition of pathogenic bacterial growth
AU2018282348A Abandoned AU2018282348A1 (en) 2013-02-04 2018-12-19 Compositions and methods
AU2020202312A Active AU2020202312B2 (en) 2013-02-04 2020-04-01 Compositions and methods for inhibition of pathogenic bacterial growth
AU2020260564A Abandoned AU2020260564A1 (en) 2013-02-04 2020-10-30 Compositions and methods
AU2023201132A Abandoned AU2023201132A1 (en) 2013-02-04 2023-02-24 Compositions and methods for inhibition of pathogenic bacterial growth
AU2024202421A Pending AU2024202421A1 (en) 2013-02-04 2024-04-12 Compositions and methods

Family Applications After (6)

Application Number Title Priority Date Filing Date
AU2014212003A Active AU2014212003C1 (en) 2013-02-04 2014-02-04 Compositions and methods for inhibition of pathogenic bacterial growth
AU2018282348A Abandoned AU2018282348A1 (en) 2013-02-04 2018-12-19 Compositions and methods
AU2020202312A Active AU2020202312B2 (en) 2013-02-04 2020-04-01 Compositions and methods for inhibition of pathogenic bacterial growth
AU2020260564A Abandoned AU2020260564A1 (en) 2013-02-04 2020-10-30 Compositions and methods
AU2023201132A Abandoned AU2023201132A1 (en) 2013-02-04 2023-02-24 Compositions and methods for inhibition of pathogenic bacterial growth
AU2024202421A Pending AU2024202421A1 (en) 2013-02-04 2024-04-12 Compositions and methods

Country Status (13)

Country Link
US (14) US10064900B2 (https=)
EP (5) EP2951285A4 (https=)
JP (6) JP2016509003A (https=)
KR (3) KR102553134B1 (https=)
CN (2) CN110917220A (https=)
AU (7) AU2014212004B2 (https=)
BR (2) BR122021010444B1 (https=)
CA (3) CA2899925A1 (https=)
HK (3) HK1218837A1 (https=)
MX (2) MX369877B (https=)
NZ (1) NZ711771A (https=)
RU (1) RU2664479C2 (https=)
WO (3) WO2014121298A2 (https=)

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US9011834B1 (en) 2015-04-21
US20190099455A1 (en) 2019-04-04
US20190192581A1 (en) 2019-06-27
CA2899926C (en) 2025-11-18
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US9585921B2 (en) 2017-03-07
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US20140328803A1 (en) 2014-11-06
US10967011B2 (en) 2021-04-06
US11185562B2 (en) 2021-11-30
EP3587558A3 (en) 2020-03-04
JP6908332B2 (ja) 2021-07-28
HK1218837A1 (zh) 2017-03-17
RU2015137399A (ru) 2017-03-10
EP3587558A2 (en) 2020-01-01
JP2021181440A (ja) 2021-11-25
AU2020260564A1 (en) 2020-11-26
US20160243172A1 (en) 2016-08-25
KR102553134B1 (ko) 2023-07-07
KR20210024683A (ko) 2021-03-05
KR20230110367A (ko) 2023-07-21
AU2018282348A1 (en) 2019-01-17
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US20240050490A1 (en) 2024-02-15
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JP2016509003A (ja) 2016-03-24
JP2019116488A (ja) 2019-07-18
BR112015018625A2 (pt) 2017-09-19
MX2015009991A (es) 2016-02-05
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HK1219022A1 (zh) 2017-03-24
RU2664479C2 (ru) 2018-08-17
US9446080B2 (en) 2016-09-20
AU2020202312A1 (en) 2020-04-23
KR20150115888A (ko) 2015-10-14
EP3584308A3 (en) 2020-03-04
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AU2014212004A1 (en) 2015-09-24
MX369877B (es) 2019-11-25
CA2899925A1 (en) 2014-08-07
CA3280244A1 (en) 2026-03-02
BR122021010444B1 (pt) 2022-07-12
HK1218559A1 (zh) 2017-02-24
WO2014121302A3 (en) 2014-10-09
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