AU2012267578B2 - Cleavable lipids - Google Patents
Cleavable lipids Download PDFInfo
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- AU2012267578B2 AU2012267578B2 AU2012267578A AU2012267578A AU2012267578B2 AU 2012267578 B2 AU2012267578 B2 AU 2012267578B2 AU 2012267578 A AU2012267578 A AU 2012267578A AU 2012267578 A AU2012267578 A AU 2012267578A AU 2012267578 B2 AU2012267578 B2 AU 2012267578B2
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- AU
- Australia
- Prior art keywords
- nanoparticle
- lipid
- pharmaceutical composition
- mrna
- polynucleotides
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
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- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
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- C12Y—ENZYMES
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- C12Y201/03—Carboxy- and carbamoyltransferases (2.1.3)
- C12Y201/03003—Ornithine carbamoyltransferase (2.1.3.3)
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- C12Y302/01022—Alpha-galactosidase (3.2.1.22)
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- C12Y302/01035—Hyaluronoglucosaminidase (3.2.1.35), i.e. hyaluronidase
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- C12Y302/01046—Galactosylceramidase (3.2.1.46)
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161494882P | 2011-06-08 | 2011-06-08 | |
US201161494745P | 2011-06-08 | 2011-06-08 | |
US61/494,882 | 2011-06-08 | ||
US61/494,745 | 2011-06-08 | ||
PCT/US2012/041663 WO2012170889A1 (en) | 2011-06-08 | 2012-06-08 | Cleavable lipids |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2012267578A1 AU2012267578A1 (en) | 2013-12-19 |
AU2012267578B2 true AU2012267578B2 (en) | 2017-04-20 |
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ID=46317534
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2012267578A Active AU2012267578B2 (en) | 2011-06-08 | 2012-06-08 | Cleavable lipids |
Country Status (9)
Country | Link |
---|---|
US (6) | US9717690B2 (ja) |
EP (7) | EP2718269B1 (ja) |
JP (5) | JP6022557B2 (ja) |
CN (2) | CN107095849A (ja) |
AU (1) | AU2012267578B2 (ja) |
CA (2) | CA3198966A1 (ja) |
DK (2) | DK2718269T3 (ja) |
ES (2) | ES2795110T3 (ja) |
WO (1) | WO2012170889A1 (ja) |
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Publication number | Priority date | Publication date | Assignee | Title |
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