AU2011290126B2 - Heterocyclic compound and use thereof - Google Patents

Heterocyclic compound and use thereof Download PDF

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Publication number
AU2011290126B2
AU2011290126B2 AU2011290126A AU2011290126A AU2011290126B2 AU 2011290126 B2 AU2011290126 B2 AU 2011290126B2 AU 2011290126 A AU2011290126 A AU 2011290126A AU 2011290126 A AU2011290126 A AU 2011290126A AU 2011290126 B2 AU2011290126 B2 AU 2011290126B2
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AU
Australia
Prior art keywords
optionally substituted
halogen atom
alkyl
group
substituted
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AU2011290126A
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AU2011290126A1 (en
Inventor
Yasutomi Asano
Eiji Honda
Toshihiro Imaeda
Masakuni Kori
Michiyo Mochizuki
Shinji Nakamura
Masashi Toyofuku
Osamu Ujikawa
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Takeda Pharmaceutical Co Ltd
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Takeda Pharmaceutical Co Ltd
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Publication of AU2011290126A1 publication Critical patent/AU2011290126A1/en
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AU2011290126A 2010-08-10 2011-08-09 Heterocyclic compound and use thereof Active AU2011290126B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2010-179577 2010-08-10
JP2010179577 2010-08-10
PCT/JP2011/068497 WO2012020848A1 (en) 2010-08-10 2011-08-09 Heterocyclic compound and use thereof

Publications (2)

Publication Number Publication Date
AU2011290126A1 AU2011290126A1 (en) 2013-03-07
AU2011290126B2 true AU2011290126B2 (en) 2016-01-07

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2011290126A Active AU2011290126B2 (en) 2010-08-10 2011-08-09 Heterocyclic compound and use thereof

Country Status (39)

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US (11) US9150591B2 (https=)
EP (1) EP2603513B1 (https=)
JP (2) JP5788496B2 (https=)
KR (1) KR101852215B1 (https=)
CN (2) CN104926837A (https=)
AR (1) AR082618A1 (https=)
AU (1) AU2011290126B2 (https=)
BR (1) BR112013002250B1 (https=)
CA (1) CA2807460C (https=)
CL (1) CL2013000380A1 (https=)
CO (1) CO6680700A2 (https=)
CR (1) CR20130066A (https=)
CY (1) CY1123507T1 (https=)
DK (1) DK2603513T3 (https=)
DO (1) DOP2013000030A (https=)
EA (1) EA022078B1 (https=)
EC (1) ECSP13012478A (https=)
ES (1) ES2793723T3 (https=)
GE (1) GEP20156216B (https=)
HR (1) HRP20200844T1 (https=)
HU (1) HUE049460T2 (https=)
IL (1) IL224452A (https=)
LT (1) LT2603513T (https=)
MA (1) MA34509B1 (https=)
MX (1) MX349470B (https=)
MY (1) MY165908A (https=)
NZ (1) NZ607593A (https=)
PE (1) PE20131116A1 (https=)
PH (1) PH12013500247A1 (https=)
PL (1) PL2603513T3 (https=)
PT (1) PT2603513T (https=)
RS (1) RS60311B1 (https=)
SG (1) SG187656A1 (https=)
SI (1) SI2603513T1 (https=)
TW (1) TWI504604B (https=)
UA (1) UA111594C2 (https=)
UY (1) UY33551A (https=)
WO (1) WO2012020848A1 (https=)
ZA (1) ZA201301120B (https=)

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US11589583B2 (en) 2013-12-03 2023-02-28 Fmc Corporation Pyrrolidinones herbicides
MX2016007259A (es) 2013-12-03 2016-08-04 Du Pont Pirrolidinonas como herbicidas.
US9944602B2 (en) 2014-07-02 2018-04-17 E. I. Du Pont De Nemours And Company Piperidinone herbicides
EP3230264B1 (en) 2014-12-08 2019-09-11 FMC Corporation 3-oxo-3-(arylamino)propanoates, a process for their preparation, and their use in preparing pyrrolidinones
EP3280709B1 (en) 2015-04-10 2021-05-26 FMC Corporation Substituted cyclic amides as herbicides
CN107531658B (zh) 2015-04-27 2021-07-27 Fmc公司 作为除草剂的丁内酯
MX373652B (es) * 2015-04-29 2020-04-02 Janssen Pharmaceutica Nv Imidazopirazinas y pirazolopirimidinas y su uso como moduladores del receptor de ampa.
ES2865330T3 (es) 2015-04-29 2021-10-15 Janssen Pharmaceutica Nv Azabenzimidazoles y su uso como moduladores del receptor AMPA
PL3294743T3 (pl) 2015-05-12 2020-03-31 Fmc Corporation Podstawione arylem związki bicykliczne jako środki chwastobójcze
WO2016196019A1 (en) 2015-05-29 2016-12-08 E I Du Pont De Nemours And Company Substituted cyclic amides as herbicides
CN107709310B (zh) 2015-06-02 2021-09-24 Fmc公司 取代的环酰胺及其作为除草剂的用途
CN108137512B (zh) 2015-07-31 2022-05-31 Fmc公司 用作除草剂的环状n-酰胺化合物
KR102579520B1 (ko) * 2015-08-06 2023-09-15 에프. 호프만-라 로슈 아게 Galnac 산 유도체의 제조 방법
US20170181292A1 (en) * 2015-12-16 2017-06-22 Rohm And Haas Electronic Materials Llc Method for forming organic coating on nickel surface
CN105669731B (zh) * 2016-01-10 2017-06-30 沧州普瑞东方科技有限公司 一种4‑(4‑烷基环己氧基)苯硼酸的合成方法
CA3047724A1 (en) 2016-12-21 2018-06-28 Fmc Corporation Nitrone herbicides
CN107892697B (zh) 2016-12-26 2020-11-03 郑州泰基鸿诺医药股份有限公司 一种[1,3]噻嗪-2-胺类化合物及应用，药物组合物
WO2018175231A1 (en) 2017-03-21 2018-09-27 Fmc Corporation Herbicidal mixture, composition and method
CA3057297A1 (en) 2017-03-21 2018-09-27 Fmc Corporation Pyrrolidinones and a process to prepare them
AR111967A1 (es) 2017-05-30 2019-09-04 Fmc Corp Amidas herbicidas
AR111839A1 (es) 2017-05-30 2019-08-21 Fmc Corp Lactamas 3-sustituidas herbicidas
US11407748B2 (en) 2017-10-06 2022-08-09 Takeda Pharmaceutical Company Limited Substituted pyrido[1,2-a]pyrimidines and pyrazino[1,2-a]pyrimidines for enhancing AMPA receptor function
ES2971497T3 (es) 2017-10-06 2024-06-05 Takeda Pharmaceuticals Co Compuestos heterocíclicos
CR20220160A (es) 2019-09-16 2022-06-16 Takeda Pharmaceuticals Co Derivados de piridazin-3(2h)-ona fusionados con azol
TW202207944A (zh) * 2020-05-15 2022-03-01 日商武田藥品工業股份有限公司 抑鬱症之治療
CN113943294A (zh) * 2020-07-15 2022-01-18 成都海博为药业有限公司 一种作为btk抑制剂的化合物及其制备方法与用途
WO2025224508A1 (en) 2024-04-22 2025-10-30 Takeda Pharmaceutical Company Limited Pharmaceutical composition for treating depressive disorders
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Also Published As

Publication number Publication date
MY165908A (en) 2018-05-18
HUE049460T2 (hu) 2020-09-28
LT2603513T (lt) 2020-05-25
AU2011290126A1 (en) 2013-03-07
CO6680700A2 (es) 2013-05-31
BR112013002250B1 (pt) 2020-10-27
EA022078B1 (ru) 2015-10-30
CN104926837A (zh) 2015-09-23
US20180162875A1 (en) 2018-06-14
US20130190291A1 (en) 2013-07-25
US20150073137A1 (en) 2015-03-12
DK2603513T3 (da) 2020-06-15
CN103180326A (zh) 2013-06-26
CL2013000380A1 (es) 2013-05-31
JP2013535408A (ja) 2013-09-12
US8916551B2 (en) 2014-12-23
CR20130066A (es) 2013-05-03
US20190263832A1 (en) 2019-08-29
NZ607593A (en) 2015-01-30
EA201390222A1 (ru) 2013-08-30
WO2012020848A8 (en) 2012-09-27
EP2603513A1 (en) 2013-06-19
TWI504604B (zh) 2015-10-21
US8575154B2 (en) 2013-11-05
MX2013001614A (es) 2013-07-05
CA2807460A1 (en) 2012-02-16
UY33551A (es) 2012-03-30
AR082618A1 (es) 2012-12-19
DOP2013000030A (es) 2013-03-15
MA34509B1 (fr) 2013-09-02
US20150353578A1 (en) 2015-12-10
JP6113789B2 (ja) 2017-04-12
US9150591B2 (en) 2015-10-06
US9884875B2 (en) 2018-02-06
US9499568B2 (en) 2016-11-22
US20240360156A1 (en) 2024-10-31
BR112013002250A2 (pt) 2016-05-24
TW201217386A (en) 2012-05-01
SI2603513T1 (sl) 2020-07-31
UA111594C2 (uk) 2016-05-25
SG187656A1 (en) 2013-03-28
CN103180326B (zh) 2015-06-10
GEP20156216B (en) 2015-01-12
PE20131116A1 (es) 2013-10-24
JP2016006080A (ja) 2016-01-14
US20120077799A1 (en) 2012-03-29
US20200317692A1 (en) 2020-10-08
MX349470B (es) 2017-07-31
CY1123507T1 (el) 2022-03-24
WO2012020848A1 (en) 2012-02-16
ZA201301120B (en) 2014-04-30
US10654874B2 (en) 2020-05-19
US11279713B2 (en) 2022-03-22
CA2807460C (en) 2018-09-18
ES2793723T3 (es) 2020-11-16
US20130184266A1 (en) 2013-07-18
US20140080817A1 (en) 2014-03-20
PT2603513T (pt) 2020-06-08
US8778934B2 (en) 2014-07-15
PH12013500247A1 (en) 2013-03-11
ECSP13012478A (es) 2013-04-30
IL224452A (en) 2017-11-30
PL2603513T3 (pl) 2020-07-27
EP2603513B1 (en) 2020-03-11
US20170022222A1 (en) 2017-01-26
RS60311B1 (sr) 2020-07-31
HRP20200844T1 (hr) 2020-08-21
KR101852215B1 (ko) 2018-04-25
KR20130138738A (ko) 2013-12-19
JP5788496B2 (ja) 2015-09-30

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