AR082618A1 - Derivados de tiadiazina, composiciones farmaceuticas y usos - Google Patents
Derivados de tiadiazina, composiciones farmaceuticas y usosInfo
- Publication number
- AR082618A1 AR082618A1 ARP110102905A ARP110102905A AR082618A1 AR 082618 A1 AR082618 A1 AR 082618A1 AR P110102905 A ARP110102905 A AR P110102905A AR P110102905 A ARP110102905 A AR P110102905A AR 082618 A1 AR082618 A1 AR 082618A1
- Authority
- AR
- Argentina
- Prior art keywords
- optionally substituted
- pyrazolo
- dioxide
- ring
- thiadiazin
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 4
- -1 7,7-diphenyl-6,7-dihydro-5H-pyrrolo [2,1-c] [1, 2,4] thiadiazol-3-ylidene Chemical group 0.000 abstract 3
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 abstract 2
- 125000000738 acetamido group Chemical group [H]C([H])([H])C(=O)N([H])[*] 0.000 abstract 2
- 125000002029 aromatic hydrocarbon group Chemical group 0.000 abstract 2
- MTZQAGJQAFMTAQ-UHFFFAOYSA-N ethyl benzoate Chemical compound CCOC(=O)C1=CC=CC=C1 MTZQAGJQAFMTAQ-UHFFFAOYSA-N 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000006850 spacer group Chemical group 0.000 abstract 2
- 102000003678 AMPA Receptors Human genes 0.000 abstract 1
- 108090000078 AMPA Receptors Proteins 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 abstract 1
- BMPZOXZLUWXVRP-UHFFFAOYSA-N N12NC(C)=C(C=3C=CC=CC=3)C2=NSC=C1C1=CC=CC=C1 Chemical compound N12NC(C)=C(C=3C=CC=CC=3)C2=NSC=C1C1=CC=CC=C1 BMPZOXZLUWXVRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 229940098779 methanesulfonic acid Drugs 0.000 abstract 1
- AFVFQIVMOAPDHO-UHFFFAOYSA-N methanesulfonic acid Substances CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 229940126585 therapeutic drug Drugs 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010179577 | 2010-08-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR082618A1 true AR082618A1 (es) | 2012-12-19 |
Family
ID=44534564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP110102905A AR082618A1 (es) | 2010-08-10 | 2011-08-09 | Derivados de tiadiazina, composiciones farmaceuticas y usos |
Country Status (39)
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT2603513T (lt) * | 2010-08-10 | 2020-05-25 | Takeda Pharmaceutical Company Limited | Heterociklinis junginys ir jo panaudojimas kaip ampa receptoriaus teigiamo alosterinio moduliatoriaus |
| EP2694472B1 (en) * | 2011-04-05 | 2020-03-11 | Takeda Pharmaceutical Company Limited | Sulfonamide derivative and use thereof |
| JP6134654B2 (ja) * | 2012-02-08 | 2017-05-24 | 武田薬品工業株式会社 | 複素環化合物およびその用途 |
| EP3008167A4 (en) * | 2013-06-13 | 2017-06-07 | VeroScience LLC | Compositions and methods for treating metabolic disorders |
| SG11201509186TA (en) | 2013-06-27 | 2016-01-28 | Pfizer | Heteroaromatic compounds and their use as dopamine d1 ligands |
| US11589583B2 (en) | 2013-12-03 | 2023-02-28 | Fmc Corporation | Pyrrolidinones herbicides |
| CA2931961C (en) | 2013-12-03 | 2023-10-31 | Andrew Duncan Satterfield | Pyrrolidinones as herbicides |
| SG11201610720VA (en) | 2014-07-02 | 2017-01-27 | Du Pont | Piperidinone herbicides |
| CN107001260B (zh) | 2014-12-08 | 2020-11-10 | Fmc公司 | 3-氧基-3-(芳氨基)丙酸酯、其制备方法、以及其在制备吡咯烷酮中的用途 |
| EP3280709B1 (en) | 2015-04-10 | 2021-05-26 | FMC Corporation | Substituted cyclic amides as herbicides |
| BR112017020094B1 (pt) | 2015-04-27 | 2022-01-11 | Fmc Corporation | Composto, composições herbicidas, mistura de herbicida e método para controlar o crescimento de vegetação indesejada |
| RS61688B1 (sr) | 2015-04-29 | 2021-05-31 | Janssen Pharmaceutica Nv | Azabenzimidazoli i njihiova upotreba kao modulatori ampa receptora |
| WO2016176457A1 (en) * | 2015-04-29 | 2016-11-03 | Janssen Pharmaceutica Nv | Imidazopyrazines and pyrazolopyrimidines and their use as ampa receptor modulators |
| JP7000160B2 (ja) | 2015-05-12 | 2022-01-19 | エフ エム シー コーポレーション | 除草剤としてのアリール置換二環式化合物 |
| JP6869192B2 (ja) | 2015-05-29 | 2021-05-12 | エフ エム シー コーポレーションFmc Corporation | 除草剤としての置換環状アミド |
| CN107709310B (zh) | 2015-06-02 | 2021-09-24 | Fmc公司 | 取代的环酰胺及其作为除草剂的用途 |
| JP6937290B2 (ja) | 2015-07-31 | 2021-09-22 | エフ エム シー コーポレーションFmc Corporation | 除草剤として有用な環状n−カルボキサミド化合物 |
| CA2982825C (en) * | 2015-08-06 | 2023-10-17 | F. Hoffmann-La Roche Ag | Processes for the preparation of galnac acid derivatives |
| US20170181292A1 (en) * | 2015-12-16 | 2017-06-22 | Rohm And Haas Electronic Materials Llc | Method for forming organic coating on nickel surface |
| CN105669731B (zh) * | 2016-01-10 | 2017-06-30 | 沧州普瑞东方科技有限公司 | 一种4‑(4‑烷基环己氧基)苯硼酸的合成方法 |
| RU2019122791A (ru) | 2016-12-21 | 2021-01-25 | Фмк Корпорейшн | Гербициды на основе нитрона |
| CN107892697B (zh) | 2016-12-26 | 2020-11-03 | 郑州泰基鸿诺医药股份有限公司 | 一种[1,3]噻嗪-2-胺类化合物及应用,药物组合物 |
| MX2019010969A (es) | 2017-03-21 | 2019-12-02 | Fmc Corp | Pirrolidinonas y proceso para prepararlas. |
| CN110740646B (zh) | 2017-03-21 | 2022-05-10 | Fmc公司 | 除草剂混合物、组合物和方法 |
| AR111967A1 (es) | 2017-05-30 | 2019-09-04 | Fmc Corp | Amidas herbicidas |
| AR111839A1 (es) | 2017-05-30 | 2019-08-21 | Fmc Corp | Lactamas 3-sustituidas herbicidas |
| ES2970624T3 (es) | 2017-10-06 | 2024-05-29 | Takeda Pharmaceuticals Co | Compuesto heterocíclico |
| EP3693360B1 (en) * | 2017-10-06 | 2023-12-13 | Takeda Pharmaceutical Company Limited | Heterocyclic compounds |
| AU2020348675B2 (en) | 2019-09-16 | 2025-11-20 | Takeda Pharmaceutical Company Limited | Azole-fused pyridazin-3(2H)-one derivatives |
| US20230338391A1 (en) * | 2020-05-15 | 2023-10-26 | Takeda Pharmaceutical Company Limited | Treatment for depression |
| CN113943294A (zh) * | 2020-07-15 | 2022-01-18 | 成都海博为药业有限公司 | 一种作为btk抑制剂的化合物及其制备方法与用途 |
| WO2025224508A1 (en) | 2024-04-22 | 2025-10-30 | Takeda Pharmaceutical Company Limited | Pharmaceutical composition for treating depressive disorders |
| WO2026050231A1 (en) | 2024-08-27 | 2026-03-05 | Neurocrine Biosciences, Inc. | Method of treating a bipolar disorder |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0437742Y2 (https=) | 1986-10-22 | 1992-09-04 | ||
| JPH0285851A (ja) * | 1988-09-22 | 1990-03-27 | Konica Corp | 新規な写真用カプラー |
| JPH037742A (ja) | 1989-06-05 | 1991-01-14 | Toyo Tire & Rubber Co Ltd | ラバーチエーン用ゴム組成物 |
| JP2874960B2 (ja) * | 1990-06-03 | 1999-03-24 | コニカ株式会社 | 新規な染料を含有するハロゲン化銀写真感光材料 |
| JPH04119890A (ja) * | 1990-09-11 | 1992-04-21 | Konica Corp | ピラゾロチアジアジン系色素 |
| JP3430375B2 (ja) * | 1993-11-12 | 2003-07-28 | コニカ株式会社 | 感熱転写材料及び該材料に好適な色素 |
| DE19704923A1 (de) | 1997-02-10 | 1998-08-13 | Hoechst Schering Agrevo Gmbh | Klebstoffhaltige Schädlingsbekämpfungsmittel |
| EP1229786A1 (en) | 1999-11-04 | 2002-08-14 | Colorado State University | Method and device for attracting insects |
| FR2801587B1 (fr) | 1999-11-30 | 2002-01-11 | Adir | Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| JP2005508352A (ja) * | 2001-10-10 | 2005-03-31 | ニューロサーチ、アクティーゼルスカブ | 新規ベンゾチアジン誘導体、その製造方法及びその使用方法 |
| FR2833955B1 (fr) * | 2001-12-21 | 2004-01-30 | Servier Lab | Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2854634B1 (fr) | 2003-05-05 | 2005-07-08 | Servier Lab | Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2865474B1 (fr) | 2004-01-26 | 2008-06-13 | Servier Lab | Nouveaux derives de benzothiazines fluorees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2879201B1 (fr) | 2004-12-10 | 2007-02-16 | Servier Lab | Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CA2655376A1 (en) | 2006-06-23 | 2007-12-27 | Nufarm Australia Limited | Phenoxy alkanoate herbicidal composition and method of preparation and use |
| US8097652B2 (en) | 2006-12-11 | 2012-01-17 | Eli Lilly And Company | AMPA receptor potentiators |
| US20080167374A1 (en) | 2007-01-09 | 2008-07-10 | Loveland Products, Inc. | Pesticide composition and method of use |
| US8487099B2 (en) * | 2007-11-05 | 2013-07-16 | Merck Sharp & Dohme Corp. | Gamma secretase modulators |
| CA2709784A1 (en) * | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| WO2009119088A1 (ja) | 2008-03-25 | 2009-10-01 | 武田薬品工業株式会社 | 複素環化合物 |
| JP2009248543A (ja) * | 2008-04-11 | 2009-10-29 | Fujifilm Corp | 光情報記録媒体および情報記録方法 |
| TW201012803A (en) | 2008-06-06 | 2010-04-01 | Organon Nv | Heterocyclic derivatives |
| EP2356115A1 (en) * | 2008-11-06 | 2011-08-17 | Schering Corporation | Gamma secretase modulators |
| TW201030002A (en) | 2009-01-16 | 2010-08-16 | Bristol Myers Squibb Co | Bicyclic compounds for the reduction of beta-amyloid production |
| JP2012051806A (ja) | 2009-02-26 | 2012-03-15 | Eisai R & D Management Co Ltd | イミダゾリルピラジン誘導体 |
| FR2943342B1 (fr) | 2009-03-20 | 2011-03-04 | Servier Lab | Nouveaux derives de benzothiadiazepines,leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| WO2010140339A1 (ja) | 2009-06-01 | 2010-12-09 | 武田薬品工業株式会社 | 複素環化合物 |
| EP2455380A4 (en) | 2009-07-13 | 2012-11-28 | Takeda Pharmaceutical | HETEROCYCLIC COMPOUND AND USE THEREOF |
| WO2011036885A1 (ja) | 2009-09-25 | 2011-03-31 | 武田薬品工業株式会社 | 複素環化合物 |
| WO2011036889A1 (ja) | 2009-09-25 | 2011-03-31 | 武田薬品工業株式会社 | 複素環化合物 |
| LT2603513T (lt) * | 2010-08-10 | 2020-05-25 | Takeda Pharmaceutical Company Limited | Heterociklinis junginys ir jo panaudojimas kaip ampa receptoriaus teigiamo alosterinio moduliatoriaus |
-
2011
- 2011-08-09 LT LTEP11749944.2T patent/LT2603513T/lt unknown
- 2011-08-09 SG SG2013007463A patent/SG187656A1/en unknown
- 2011-08-09 MX MX2013001614A patent/MX349470B/es active IP Right Grant
- 2011-08-09 MA MA35708A patent/MA34509B1/fr unknown
- 2011-08-09 BR BR112013002250-7A patent/BR112013002250B1/pt active IP Right Grant
- 2011-08-09 CN CN201180048970.3A patent/CN103180326B/zh active Active
- 2011-08-09 RS RS20200574A patent/RS60311B1/sr unknown
- 2011-08-09 PL PL11749944T patent/PL2603513T3/pl unknown
- 2011-08-09 TW TW100128311A patent/TWI504604B/zh active
- 2011-08-09 NZ NZ607593A patent/NZ607593A/en unknown
- 2011-08-09 CN CN201510259936.0A patent/CN104926837A/zh active Pending
- 2011-08-09 CA CA2807460A patent/CA2807460C/en active Active
- 2011-08-09 HU HUE11749944A patent/HUE049460T2/hu unknown
- 2011-08-09 DK DK11749944.2T patent/DK2603513T3/da active
- 2011-08-09 PT PT117499442T patent/PT2603513T/pt unknown
- 2011-08-09 EA EA201390222A patent/EA022078B1/ru not_active IP Right Cessation
- 2011-08-09 GE GEAP201113021A patent/GEP20156216B/en unknown
- 2011-08-09 HR HRP20200844TT patent/HRP20200844T1/hr unknown
- 2011-08-09 MY MYPI2013000428A patent/MY165908A/en unknown
- 2011-08-09 PH PH1/2013/500247A patent/PH12013500247A1/en unknown
- 2011-08-09 KR KR1020137006113A patent/KR101852215B1/ko active Active
- 2011-08-09 EP EP11749944.2A patent/EP2603513B1/en active Active
- 2011-08-09 US US13/206,113 patent/US8575154B2/en active Active
- 2011-08-09 WO PCT/JP2011/068497 patent/WO2012020848A1/en not_active Ceased
- 2011-08-09 ES ES11749944T patent/ES2793723T3/es active Active
- 2011-08-09 SI SI201131887T patent/SI2603513T1/sl unknown
- 2011-08-09 UY UY0001033551A patent/UY33551A/es not_active Application Discontinuation
- 2011-08-09 PE PE2013000244A patent/PE20131116A1/es active IP Right Grant
- 2011-08-09 JP JP2013506362A patent/JP5788496B2/ja active Active
- 2011-08-09 AU AU2011290126A patent/AU2011290126B2/en active Active
- 2011-08-09 AR ARP110102905A patent/AR082618A1/es active IP Right Grant
- 2011-08-09 US US13/816,137 patent/US9150591B2/en active Active
- 2011-09-08 UA UAA201302884A patent/UA111594C2/uk unknown
-
2013
- 2013-01-28 IL IL224452A patent/IL224452A/en active IP Right Grant
- 2013-02-05 DO DO2013000030A patent/DOP2013000030A/es unknown
- 2013-02-07 CL CL2013000380A patent/CL2013000380A1/es unknown
- 2013-02-12 ZA ZA2013/01120A patent/ZA201301120B/en unknown
- 2013-02-18 CR CR20130066A patent/CR20130066A/es unknown
- 2013-02-22 US US13/774,707 patent/US8916551B2/en active Active
- 2013-02-22 US US13/774,635 patent/US8778934B2/en active Active
- 2013-03-06 EC ECSP13012478 patent/ECSP13012478A/es unknown
- 2013-03-07 CO CO13046020A patent/CO6680700A2/es active IP Right Grant
-
2014
- 2014-11-13 US US14/540,699 patent/US20150073137A1/en not_active Abandoned
-
2015
- 2015-07-21 US US14/804,935 patent/US9499568B2/en active Active
- 2015-07-29 JP JP2015149216A patent/JP6113789B2/ja active Active
-
2016
- 2016-10-10 US US15/289,650 patent/US9884875B2/en active Active
-
2017
- 2017-12-18 US US15/845,621 patent/US20180162875A1/en not_active Abandoned
-
2019
- 2019-01-24 US US16/256,773 patent/US10654874B2/en active Active
-
2020
- 2020-03-23 US US16/827,316 patent/US11279713B2/en active Active
- 2020-05-25 CY CY20201100475T patent/CY1123507T1/el unknown
-
2024
- 2024-03-01 US US18/592,897 patent/US20240360156A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR082618A1 (es) | Derivados de tiadiazina, composiciones farmaceuticas y usos | |
| AR084011A1 (es) | Compuestos nitrogenados heterociclicos utiles para el tratamiento de infecciones por el virus sincitial respiratorio (rsv), proceso para prepararlos y composiciones farmaceuticas que los contienen | |
| UY35377A (es) | Compuestos de 1,3-oxazin-2-amina fusionados con ciclopropilo perfluorado como inhibidores de beta-secretasa y métodos de uso | |
| AR085960A1 (es) | 1,3-oxazinas como inhibidores de la bace1 y/o de la bace2 | |
| AR070395A1 (es) | Derivados de 4,5-dihidro-oxazol-2-il- amina | |
| CO6612267A2 (es) | Nuevos derivados de 1,1 dióxido- 5 fenil- 2,3,4-5tetrahidro- 1,4-benzotiazepina y composiciones farmaceúticas que los comprenden | |
| PE20130382A1 (es) | Derivados de n-(imidazopirimidin-7-il)-heteroarilamida y su uso como inhibidores de pde10a | |
| AR084849A1 (es) | Derivados de oxazina y su uso en el tratamiento de trastornos neurologicos | |
| CO6400220A2 (es) | Derivados de sulfonamida | |
| PA8815001A1 (es) | Piridinil amidas para el tratamiento de trastornos del snc y metabolicos | |
| AR054560A1 (es) | Espiropiperidina como inhibidores de beta-secretasa para el tratamiento de la enfermedad de alzheimer | |
| AR078833A1 (es) | Derivados de heteroarilos que contienen nitrogeno como inhibidores dela cinasa jak3 | |
| AR070274A1 (es) | Derivados arilamida diazepinopirimidona sustituidos utiles en el tratamiento y/o prevencion de enfermedades neurodegenerativas y otras, provocadas por la actividad anormal de quinasas gsk3beta, medicamentos que los contienen y proceso de preparacion e intermediarios. | |
| AR054035A1 (es) | Derivados benzodioxano y benzodioxolano y uso de los mismos | |
| AR075583A1 (es) | Derivados de isoxazol/o-piridina con eslabon etilo o etenilo | |
| ES2570756T3 (es) | Derivados pirimidinilpirrolopiridinona sustituidos, proceso para su preparación y su uso como inhibidores de cinasa | |
| AR079510A1 (es) | Derivados de quinolinamida moduladores alostericos positivos de receptores muscarinicos m1, composiciones farmaceuticas que los contienen y uso de los mismos en el tratamiento del alzheimer, esquizofrenia y otras patologias del sistema nervioso central. | |
| BR112015015275A2 (pt) | composto heterocíclico substituído por halogênio | |
| UY33969A (es) | Inhibidores tricíclicos fusionados dobles de las cdk 4/6 y de la flt3 | |
| CU24327B1 (es) | Derivados de 1,4-benzotiazepina, útiles para tratar trastornos y enfermedades asociadas con los receptores de rianodina, y las composiciones farmacéuticas que les comprenden | |
| AR072962A1 (es) | Derivados de pirimidin-4-ona sustituidos | |
| AR087915A1 (es) | N-(3-(2-amino-6,6-difluor-4,4a,5,6,7,7a-hexahidro-ciclopenta-[e][1,3]oxazin-4-il)-fenil)-amidas como inhibidores de la bace1 | |
| CU23761B7 (es) | Nuevos derivados de diosmetina, su procedimiento de preparación y las composiciones farmacéuticas que los contienen | |
| AR066421A1 (es) | Compuestos derivados de piridona | |
| AR069607A1 (es) | Inhibidores de la estearoil-coa desaturasa |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |