JP5788496B2 - 複素環化合物およびその用途 - Google Patents

複素環化合物およびその用途 Download PDF

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Publication number
JP5788496B2
JP5788496B2 JP2013506362A JP2013506362A JP5788496B2 JP 5788496 B2 JP5788496 B2 JP 5788496B2 JP 2013506362 A JP2013506362 A JP 2013506362A JP 2013506362 A JP2013506362 A JP 2013506362A JP 5788496 B2 JP5788496 B2 JP 5788496B2
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group
optionally substituted
ring
compound
alkyl
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Japanese (ja)
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JP2013535408A5 (https=
JP2013535408A (ja
Inventor
正城 郡
郡　　正城
稔博 今枝
稔博 今枝
信二 中村
信二 中村
昌志 豊福
昌志 豊福
栄治 本多
栄治 本多
恭臣 浅野
恭臣 浅野
治 宇治川
治 宇治川
倫代 望月
倫代 望月
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Takeda Pharmaceutical Co Ltd
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Takeda Pharmaceutical Co Ltd
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Priority to JP2013506362A priority Critical patent/JP5788496B2/ja
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Publication of JP2013535408A5 publication Critical patent/JP2013535408A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
JP2013506362A 2010-08-10 2011-08-09 複素環化合物およびその用途 Active JP5788496B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2013506362A JP5788496B2 (ja) 2010-08-10 2011-08-09 複素環化合物およびその用途

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2010179577 2010-08-10
JP2010179577 2010-08-10
PCT/JP2011/068497 WO2012020848A1 (en) 2010-08-10 2011-08-09 Heterocyclic compound and use thereof
JP2013506362A JP5788496B2 (ja) 2010-08-10 2011-08-09 複素環化合物およびその用途

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015149216A Division JP6113789B2 (ja) 2010-08-10 2015-07-29 複素環化合物およびその用途

Publications (3)

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JP2013535408A JP2013535408A (ja) 2013-09-12
JP2013535408A5 JP2013535408A5 (https=) 2014-09-18
JP5788496B2 true JP5788496B2 (ja) 2015-09-30

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JP2013506362A Active JP5788496B2 (ja) 2010-08-10 2011-08-09 複素環化合物およびその用途
JP2015149216A Active JP6113789B2 (ja) 2010-08-10 2015-07-29 複素環化合物およびその用途

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US (11) US9150591B2 (https=)
EP (1) EP2603513B1 (https=)
JP (2) JP5788496B2 (https=)
KR (1) KR101852215B1 (https=)
CN (2) CN104926837A (https=)
AR (1) AR082618A1 (https=)
AU (1) AU2011290126B2 (https=)
BR (1) BR112013002250B1 (https=)
CA (1) CA2807460C (https=)
CL (1) CL2013000380A1 (https=)
CO (1) CO6680700A2 (https=)
CR (1) CR20130066A (https=)
CY (1) CY1123507T1 (https=)
DK (1) DK2603513T3 (https=)
DO (1) DOP2013000030A (https=)
EA (1) EA022078B1 (https=)
EC (1) ECSP13012478A (https=)
ES (1) ES2793723T3 (https=)
GE (1) GEP20156216B (https=)
HR (1) HRP20200844T1 (https=)
HU (1) HUE049460T2 (https=)
IL (1) IL224452A (https=)
LT (1) LT2603513T (https=)
MA (1) MA34509B1 (https=)
MX (1) MX349470B (https=)
MY (1) MY165908A (https=)
NZ (1) NZ607593A (https=)
PE (1) PE20131116A1 (https=)
PH (1) PH12013500247A1 (https=)
PL (1) PL2603513T3 (https=)
PT (1) PT2603513T (https=)
RS (1) RS60311B1 (https=)
SG (1) SG187656A1 (https=)
SI (1) SI2603513T1 (https=)
TW (1) TWI504604B (https=)
UA (1) UA111594C2 (https=)
UY (1) UY33551A (https=)
WO (1) WO2012020848A1 (https=)
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JPWO2013118845A1 (ja) * 2012-02-08 2015-05-11 武田薬品工業株式会社 複素環化合物およびその用途
JP2016006080A (ja) * 2010-08-10 2016-01-14 武田薬品工業株式会社 複素環化合物およびその用途

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EP3230264B1 (en) 2014-12-08 2019-09-11 FMC Corporation 3-oxo-3-(arylamino)propanoates, a process for their preparation, and their use in preparing pyrrolidinones
EP3280709B1 (en) 2015-04-10 2021-05-26 FMC Corporation Substituted cyclic amides as herbicides
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KR102579520B1 (ko) * 2015-08-06 2023-09-15 에프. 호프만-라 로슈 아게 Galnac 산 유도체의 제조 방법
US20170181292A1 (en) * 2015-12-16 2017-06-22 Rohm And Haas Electronic Materials Llc Method for forming organic coating on nickel surface
CN105669731B (zh) * 2016-01-10 2017-06-30 沧州普瑞东方科技有限公司 一种4‑(4‑烷基环己氧基)苯硼酸的合成方法
CA3047724A1 (en) 2016-12-21 2018-06-28 Fmc Corporation Nitrone herbicides
CN107892697B (zh) 2016-12-26 2020-11-03 郑州泰基鸿诺医药股份有限公司 一种[1,3]噻嗪-2-胺类化合物及应用，药物组合物
WO2018175231A1 (en) 2017-03-21 2018-09-27 Fmc Corporation Herbicidal mixture, composition and method
CA3057297A1 (en) 2017-03-21 2018-09-27 Fmc Corporation Pyrrolidinones and a process to prepare them
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ES2971497T3 (es) 2017-10-06 2024-06-05 Takeda Pharmaceuticals Co Compuestos heterocíclicos
CR20220160A (es) 2019-09-16 2022-06-16 Takeda Pharmaceuticals Co Derivados de piridazin-3(2h)-ona fusionados con azol
TW202207944A (zh) * 2020-05-15 2022-03-01 日商武田藥品工業股份有限公司 抑鬱症之治療
CN113943294A (zh) * 2020-07-15 2022-01-18 成都海博为药业有限公司 一种作为btk抑制剂的化合物及其制备方法与用途
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JP2016006080A (ja) * 2010-08-10 2016-01-14 武田薬品工業株式会社 複素環化合物およびその用途
JPWO2013118845A1 (ja) * 2012-02-08 2015-05-11 武田薬品工業株式会社 複素環化合物およびその用途

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MY165908A (en) 2018-05-18
HUE049460T2 (hu) 2020-09-28
LT2603513T (lt) 2020-05-25
AU2011290126A1 (en) 2013-03-07
CO6680700A2 (es) 2013-05-31
BR112013002250B1 (pt) 2020-10-27
EA022078B1 (ru) 2015-10-30
CN104926837A (zh) 2015-09-23
US20180162875A1 (en) 2018-06-14
US20130190291A1 (en) 2013-07-25
US20150073137A1 (en) 2015-03-12
DK2603513T3 (da) 2020-06-15
CN103180326A (zh) 2013-06-26
CL2013000380A1 (es) 2013-05-31
JP2013535408A (ja) 2013-09-12
US8916551B2 (en) 2014-12-23
CR20130066A (es) 2013-05-03
US20190263832A1 (en) 2019-08-29
NZ607593A (en) 2015-01-30
EA201390222A1 (ru) 2013-08-30
WO2012020848A8 (en) 2012-09-27
EP2603513A1 (en) 2013-06-19
TWI504604B (zh) 2015-10-21
US8575154B2 (en) 2013-11-05
MX2013001614A (es) 2013-07-05
CA2807460A1 (en) 2012-02-16
UY33551A (es) 2012-03-30
AR082618A1 (es) 2012-12-19
DOP2013000030A (es) 2013-03-15
MA34509B1 (fr) 2013-09-02
US20150353578A1 (en) 2015-12-10
JP6113789B2 (ja) 2017-04-12
US9150591B2 (en) 2015-10-06
US9884875B2 (en) 2018-02-06
US9499568B2 (en) 2016-11-22
US20240360156A1 (en) 2024-10-31
BR112013002250A2 (pt) 2016-05-24
TW201217386A (en) 2012-05-01
AU2011290126B2 (en) 2016-01-07
SI2603513T1 (sl) 2020-07-31
UA111594C2 (uk) 2016-05-25
SG187656A1 (en) 2013-03-28
CN103180326B (zh) 2015-06-10
GEP20156216B (en) 2015-01-12
PE20131116A1 (es) 2013-10-24
JP2016006080A (ja) 2016-01-14
US20120077799A1 (en) 2012-03-29
US20200317692A1 (en) 2020-10-08
MX349470B (es) 2017-07-31
CY1123507T1 (el) 2022-03-24
WO2012020848A1 (en) 2012-02-16
ZA201301120B (en) 2014-04-30
US10654874B2 (en) 2020-05-19
US11279713B2 (en) 2022-03-22
CA2807460C (en) 2018-09-18
ES2793723T3 (es) 2020-11-16
US20130184266A1 (en) 2013-07-18
US20140080817A1 (en) 2014-03-20
PT2603513T (pt) 2020-06-08
US8778934B2 (en) 2014-07-15
PH12013500247A1 (en) 2013-03-11
ECSP13012478A (es) 2013-04-30
IL224452A (en) 2017-11-30
PL2603513T3 (pl) 2020-07-27
EP2603513B1 (en) 2020-03-11
US20170022222A1 (en) 2017-01-26
RS60311B1 (sr) 2020-07-31
HRP20200844T1 (hr) 2020-08-21
KR101852215B1 (ko) 2018-04-25
KR20130138738A (ko) 2013-12-19

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