AU2011290126B2 - Heterocyclic compound and use thereof - Google Patents

Heterocyclic compound and use thereof Download PDF

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Publication number
AU2011290126B2
AU2011290126B2 AU2011290126A AU2011290126A AU2011290126B2 AU 2011290126 B2 AU2011290126 B2 AU 2011290126B2 AU 2011290126 A AU2011290126 A AU 2011290126A AU 2011290126 A AU2011290126 A AU 2011290126A AU 2011290126 B2 AU2011290126 B2 AU 2011290126B2
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AU
Australia
Prior art keywords
optionally substituted
halogen atom
alkyl
group
substituted
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AU2011290126A
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AU2011290126A1 (en
Inventor
Yasutomi Asano
Eiji Honda
Toshihiro Imaeda
Masakuni Kori
Michiyo Mochizuki
Shinji Nakamura
Masashi Toyofuku
Osamu Ujikawa
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Takeda Pharmaceutical Co Ltd
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Takeda Pharmaceutical Co Ltd
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Publication of AU2011290126A1 publication Critical patent/AU2011290126A1/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AU2011290126A 2010-08-10 2011-08-09 Heterocyclic compound and use thereof Active AU2011290126B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2010179577 2010-08-10
JP2010-179577 2010-08-10
PCT/JP2011/068497 WO2012020848A1 (en) 2010-08-10 2011-08-09 Heterocyclic compound and use thereof

Publications (2)

Publication Number Publication Date
AU2011290126A1 AU2011290126A1 (en) 2013-03-07
AU2011290126B2 true AU2011290126B2 (en) 2016-01-07

Family

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Application Number Title Priority Date Filing Date
AU2011290126A Active AU2011290126B2 (en) 2010-08-10 2011-08-09 Heterocyclic compound and use thereof

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US (11) US8575154B2 (enrdf_load_stackoverflow)
EP (1) EP2603513B1 (enrdf_load_stackoverflow)
JP (2) JP5788496B2 (enrdf_load_stackoverflow)
KR (1) KR101852215B1 (enrdf_load_stackoverflow)
CN (2) CN103180326B (enrdf_load_stackoverflow)
AR (1) AR082618A1 (enrdf_load_stackoverflow)
AU (1) AU2011290126B2 (enrdf_load_stackoverflow)
BR (1) BR112013002250B1 (enrdf_load_stackoverflow)
CA (1) CA2807460C (enrdf_load_stackoverflow)
CL (1) CL2013000380A1 (enrdf_load_stackoverflow)
CO (1) CO6680700A2 (enrdf_load_stackoverflow)
CR (1) CR20130066A (enrdf_load_stackoverflow)
CY (1) CY1123507T1 (enrdf_load_stackoverflow)
DK (1) DK2603513T3 (enrdf_load_stackoverflow)
DO (1) DOP2013000030A (enrdf_load_stackoverflow)
EA (1) EA022078B1 (enrdf_load_stackoverflow)
EC (1) ECSP13012478A (enrdf_load_stackoverflow)
ES (1) ES2793723T3 (enrdf_load_stackoverflow)
GE (1) GEP20156216B (enrdf_load_stackoverflow)
HR (1) HRP20200844T1 (enrdf_load_stackoverflow)
HU (1) HUE049460T2 (enrdf_load_stackoverflow)
IL (1) IL224452A (enrdf_load_stackoverflow)
LT (1) LT2603513T (enrdf_load_stackoverflow)
MA (1) MA34509B1 (enrdf_load_stackoverflow)
MX (1) MX349470B (enrdf_load_stackoverflow)
MY (1) MY165908A (enrdf_load_stackoverflow)
NZ (1) NZ607593A (enrdf_load_stackoverflow)
PE (1) PE20131116A1 (enrdf_load_stackoverflow)
PH (1) PH12013500247A1 (enrdf_load_stackoverflow)
PL (1) PL2603513T3 (enrdf_load_stackoverflow)
PT (1) PT2603513T (enrdf_load_stackoverflow)
RS (1) RS60311B1 (enrdf_load_stackoverflow)
SG (1) SG187656A1 (enrdf_load_stackoverflow)
SI (1) SI2603513T1 (enrdf_load_stackoverflow)
TW (1) TWI504604B (enrdf_load_stackoverflow)
UA (1) UA111594C2 (enrdf_load_stackoverflow)
UY (1) UY33551A (enrdf_load_stackoverflow)
WO (1) WO2012020848A1 (enrdf_load_stackoverflow)
ZA (1) ZA201301120B (enrdf_load_stackoverflow)

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EA028637B1 (ru) 2013-06-27 2017-12-29 Пфайзер Инк. Гетероароматические соединения и их применение в качестве лигандов к дофаминовым d1-рецепторам
US11589583B2 (en) 2013-12-03 2023-02-28 Fmc Corporation Pyrrolidinones herbicides
CA2931961C (en) 2013-12-03 2023-10-31 Andrew Duncan Satterfield Pyrrolidinones as herbicides
CA2953548C (en) 2014-07-02 2023-05-09 E I Du Pont De Nemours And Company Piperidinone herbicides
MX382656B (es) 2014-12-08 2025-03-13 Fmc Corp Star 3-oxo-3-(arilamino) propanoatos, proceso para su preparación y su uso en la preparación de pirrolidinonas.
JP6956637B2 (ja) 2015-04-10 2021-11-02 エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ 除草剤としての置換環状アミド
JP6835740B2 (ja) 2015-04-27 2021-02-24 エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ 除草剤としてのブチロラクトン
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CN107567452B (zh) * 2015-04-29 2020-07-07 詹森药业有限公司 咪唑并哌嗪和吡唑并嘧啶以及它们作为ampa受体调节剂的用途
CN107592862B (zh) 2015-05-12 2021-06-15 Fmc公司 作为除草剂的芳基取代的双环化合物
US10906873B2 (en) 2015-05-29 2021-02-02 Fmc Corporation Substituted cyclic amides as herbicides
CN107709310B (zh) 2015-06-02 2021-09-24 Fmc公司 取代的环酰胺及其作为除草剂的用途
WO2017023515A1 (en) 2015-07-31 2017-02-09 E. I. Du Pont De Nemours And Company Cyclic n-carboxamide compounds useful as herbicides
CA2982825C (en) * 2015-08-06 2023-10-17 F. Hoffmann-La Roche Ag Processes for the preparation of galnac acid derivatives
US20170181292A1 (en) * 2015-12-16 2017-06-22 Rohm And Haas Electronic Materials Llc Method for forming organic coating on nickel surface
CN105669731B (zh) * 2016-01-10 2017-06-30 沧州普瑞东方科技有限公司 一种4‑(4‑烷基环己氧基)苯硼酸的合成方法
CA3047724A1 (en) 2016-12-21 2018-06-28 Fmc Corporation Nitrone herbicides
CN107892697B (zh) 2016-12-26 2020-11-03 郑州泰基鸿诺医药股份有限公司 一种[1,3]噻嗪-2-胺类化合物及应用，药物组合物
US11919859B2 (en) 2017-03-21 2024-03-05 Fmc Corporation Herbicidal mixture, composition and method
US10875838B2 (en) 2017-03-21 2020-12-29 Fmc Corporation Pyrrolidinones and a process to prepare them
AR111839A1 (es) 2017-05-30 2019-08-21 Fmc Corp Lactamas 3-sustituidas herbicidas
AR111967A1 (es) 2017-05-30 2019-09-04 Fmc Corp Amidas herbicidas
WO2019070043A1 (ja) 2017-10-06 2019-04-11 武田薬品工業株式会社 複素環化合物
ES2971497T3 (es) 2017-10-06 2024-06-05 Takeda Pharmaceuticals Co Compuestos heterocíclicos
AR119971A1 (es) 2019-09-16 2022-01-26 Takeda Pharmaceuticals Co Derivados de piridazin-3(2h)-ona fusionados con azol
WO2021229294A1 (en) 2020-05-15 2021-11-18 Takeda Pharmaceutical Company Limited Treatment for depression
CN113943294A (zh) * 2020-07-15 2022-01-18 成都海博为药业有限公司 一种作为btk抑制剂的化合物及其制备方法与用途

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JP2016006080A (ja) 2016-01-14
US20240360156A1 (en) 2024-10-31
DK2603513T3 (da) 2020-06-15
CN103180326A (zh) 2013-06-26
US20150073137A1 (en) 2015-03-12
TWI504604B (zh) 2015-10-21
CN103180326B (zh) 2015-06-10
US11279713B2 (en) 2022-03-22
SI2603513T1 (sl) 2020-07-31
UA111594C2 (uk) 2016-05-25
DOP2013000030A (es) 2013-03-15
US20120077799A1 (en) 2012-03-29
EA201390222A1 (ru) 2013-08-30
CY1123507T1 (el) 2022-03-24
WO2012020848A1 (en) 2012-02-16
ZA201301120B (en) 2014-04-30
WO2012020848A8 (en) 2012-09-27
MY165908A (en) 2018-05-18
EP2603513A1 (en) 2013-06-19
PH12013500247A1 (en) 2013-03-11
CA2807460C (en) 2018-09-18
JP6113789B2 (ja) 2017-04-12
US20140080817A1 (en) 2014-03-20
RS60311B1 (sr) 2020-07-31
UY33551A (es) 2012-03-30
TW201217386A (en) 2012-05-01
EA022078B1 (ru) 2015-10-30
US8575154B2 (en) 2013-11-05
US20200317692A1 (en) 2020-10-08
JP5788496B2 (ja) 2015-09-30
GEP20156216B (en) 2015-01-12
CN104926837A (zh) 2015-09-23
AR082618A1 (es) 2012-12-19
SG187656A1 (en) 2013-03-28
CR20130066A (es) 2013-05-03
US8778934B2 (en) 2014-07-15
US10654874B2 (en) 2020-05-19
US20190263832A1 (en) 2019-08-29
MX2013001614A (es) 2013-07-05
JP2013535408A (ja) 2013-09-12
US9499568B2 (en) 2016-11-22
CL2013000380A1 (es) 2013-05-31
US9150591B2 (en) 2015-10-06
ECSP13012478A (es) 2013-04-30
HRP20200844T1 (hr) 2020-08-21
US20130184266A1 (en) 2013-07-18
PE20131116A1 (es) 2013-10-24
CO6680700A2 (es) 2013-05-31
NZ607593A (en) 2015-01-30
US20180162875A1 (en) 2018-06-14
ES2793723T3 (es) 2020-11-16
US9884875B2 (en) 2018-02-06
BR112013002250B1 (pt) 2020-10-27
AU2011290126A1 (en) 2013-03-07
US20130190291A1 (en) 2013-07-25
US20170022222A1 (en) 2017-01-26
IL224452A (en) 2017-11-30
MX349470B (es) 2017-07-31
US20150353578A1 (en) 2015-12-10
PL2603513T3 (pl) 2020-07-27
MA34509B1 (fr) 2013-09-02
LT2603513T (lt) 2020-05-25
US8916551B2 (en) 2014-12-23
KR101852215B1 (ko) 2018-04-25
BR112013002250A2 (pt) 2016-05-24
PT2603513T (pt) 2020-06-08
HUE049460T2 (hu) 2020-09-28
EP2603513B1 (en) 2020-03-11
CA2807460A1 (en) 2012-02-16
KR20130138738A (ko) 2013-12-19

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