AU2008254915B2 - Quinoline derivatives as PI3 kinase inhibitors - Google Patents
Quinoline derivatives as PI3 kinase inhibitors Download PDFInfo
- Publication number
- AU2008254915B2 AU2008254915B2 AU2008254915A AU2008254915A AU2008254915B2 AU 2008254915 B2 AU2008254915 B2 AU 2008254915B2 AU 2008254915 A AU2008254915 A AU 2008254915A AU 2008254915 A AU2008254915 A AU 2008254915A AU 2008254915 B2 AU2008254915 B2 AU 2008254915B2
- Authority
- AU
- Australia
- Prior art keywords
- pyridinyl
- quinolinyl
- ide
- substituted
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2012202710A AU2012202710A1 (en) | 2007-05-18 | 2012-05-09 | Quinoline derivatives as P13 kinase inhibitors |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93876107P | 2007-05-18 | 2007-05-18 | |
| US60/938,761 | 2007-05-18 | ||
| PCT/US2008/063819 WO2008144463A1 (en) | 2007-05-18 | 2008-05-16 | Quinoline derivatives as pi3 kinase inhibitors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012202710A Division AU2012202710A1 (en) | 2007-05-18 | 2012-05-09 | Quinoline derivatives as P13 kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2008254915A1 AU2008254915A1 (en) | 2008-11-27 |
| AU2008254915B2 true AU2008254915B2 (en) | 2012-02-09 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2008254915A Ceased AU2008254915B2 (en) | 2007-05-18 | 2008-05-16 | Quinoline derivatives as PI3 kinase inhibitors |
Country Status (31)
| Country | Link |
|---|---|
| US (6) | US8404837B2 (OSRAM) |
| EP (3) | EP2596793B1 (OSRAM) |
| JP (3) | JP4814396B2 (OSRAM) |
| KR (1) | KR101458660B1 (OSRAM) |
| CN (1) | CN101754759B (OSRAM) |
| AR (1) | AR066614A1 (OSRAM) |
| AU (1) | AU2008254915B2 (OSRAM) |
| BR (1) | BRPI0811761A2 (OSRAM) |
| CA (1) | CA2686016C (OSRAM) |
| CL (1) | CL2008001457A1 (OSRAM) |
| CO (1) | CO6241101A2 (OSRAM) |
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