SG11202012447YA - Rapamycin analogs and uses thereof - Google Patents
Rapamycin analogs and uses thereofInfo
- Publication number
- SG11202012447YA SG11202012447YA SG11202012447YA SG11202012447YA SG11202012447YA SG 11202012447Y A SG11202012447Y A SG 11202012447YA SG 11202012447Y A SG11202012447Y A SG 11202012447YA SG 11202012447Y A SG11202012447Y A SG 11202012447YA SG 11202012447Y A SG11202012447Y A SG 11202012447YA
- Authority
- SG
- Singapore
- Prior art keywords
- rapamycin analogs
- rapamycin
- analogs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862685666P | 2018-06-15 | 2018-06-15 | |
| PCT/US2019/037507 WO2019241789A1 (en) | 2018-06-15 | 2019-06-17 | Rapamycin analogs and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202012447YA true SG11202012447YA (en) | 2021-01-28 |
Family
ID=68842366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202012447YA SG11202012447YA (en) | 2018-06-15 | 2019-06-17 | Rapamycin analogs and uses thereof |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US10980784B2 (en) |
| EP (2) | EP4302827A3 (en) |
| JP (2) | JP7382353B2 (en) |
| KR (1) | KR20210021534A (en) |
| CN (2) | CN112423843B (en) |
| AU (1) | AU2019286524A1 (en) |
| BR (1) | BR112020025283A2 (en) |
| CA (1) | CA3103282A1 (en) |
| CO (1) | CO2020015747A2 (en) |
| EA (1) | EA202092692A1 (en) |
| IL (1) | IL279329A (en) |
| MX (1) | MX2020013630A (en) |
| SG (1) | SG11202012447YA (en) |
| WO (1) | WO2019241789A1 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019241789A1 (en) | 2018-06-15 | 2019-12-19 | Navitor Pharmaceuticals, Inc. | Rapamycin analogs and uses thereof |
| WO2020154447A1 (en) | 2019-01-22 | 2020-07-30 | Aeovian Pharmaceuticals, Inc. | Mtorc modulators and uses thereof |
| TW202134234A (en) * | 2019-12-05 | 2021-09-16 | 美商奈維特製藥公司 | Rapamycin analogs and uses thereof |
| JP2023530778A (en) | 2020-03-27 | 2023-07-19 | エオビアン ファーマシューティカルズ， インコーポレイテッド | MTORC1 modulators and uses thereof |
| CN116322677A (en) * | 2020-07-21 | 2023-06-23 | 艾奥维安制药公司 | MTORC1 modulators and uses thereof |
| EP4281463A1 (en) * | 2021-01-22 | 2023-11-29 | JANSSEN Pharmaceutica NV | Rapamycin analogs and uses thereof |
| CN115097046B (en) * | 2022-07-07 | 2023-09-26 | 国药集团川抗制药有限公司 | Method for separating rapamycin and impurities thereof |
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| JP2023530778A (en) | 2020-03-27 | 2023-07-19 | エオビアン ファーマシューティカルズ， インコーポレイテッド | MTORC1 modulators and uses thereof |
| CN116322677A (en) | 2020-07-21 | 2023-06-23 | 艾奥维安制药公司 | MTORC1 modulators and uses thereof |
-
2019
- 2019-06-17 WO PCT/US2019/037507 patent/WO2019241789A1/en active Application Filing
- 2019-06-17 EA EA202092692A patent/EA202092692A1/en unknown
- 2019-06-17 JP JP2020569883A patent/JP7382353B2/en active Active
- 2019-06-17 MX MX2020013630A patent/MX2020013630A/en unknown
- 2019-06-17 US US16/443,298 patent/US10980784B2/en active Active
- 2019-06-17 CN CN201980047384.3A patent/CN112423843B/en active Active
- 2019-06-17 BR BR112020025283-2A patent/BR112020025283A2/en unknown
- 2019-06-17 AU AU2019286524A patent/AU2019286524A1/en active Pending
- 2019-06-17 SG SG11202012447YA patent/SG11202012447YA/en unknown
- 2019-06-17 EP EP23209520.8A patent/EP4302827A3/en active Pending
- 2019-06-17 KR KR1020217001301A patent/KR20210021534A/en unknown
- 2019-06-17 EP EP19819402.9A patent/EP3813946B1/en active Active
- 2019-06-17 CA CA3103282A patent/CA3103282A1/en active Pending
- 2019-06-17 CN CN202311390677.6A patent/CN117843659A/en active Pending
-
2020
- 2020-11-25 US US17/104,771 patent/US11944605B2/en active Active
- 2020-12-09 IL IL279329A patent/IL279329A/en unknown
- 2020-12-15 CO CONC2020/0015747A patent/CO2020015747A2/en unknown
-
2023
- 2023-11-06 JP JP2023189414A patent/JP2024012524A/en active Pending
- 2023-12-04 US US18/528,215 patent/US20240173305A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20240173305A1 (en) | 2024-05-30 |
| US20210220339A1 (en) | 2021-07-22 |
| JP7382353B2 (en) | 2023-11-16 |
| AU2019286524A1 (en) | 2021-01-07 |
| KR20210021534A (en) | 2021-02-26 |
| EP3813946A1 (en) | 2021-05-05 |
| CN117843659A (en) | 2024-04-09 |
| CO2020015747A2 (en) | 2020-12-21 |
| EP3813946A4 (en) | 2022-06-01 |
| MX2020013630A (en) | 2021-04-28 |
| EA202092692A1 (en) | 2021-04-21 |
| US11944605B2 (en) | 2024-04-02 |
| US10980784B2 (en) | 2021-04-20 |
| IL279329A (en) | 2021-01-31 |
| CN112423843A (en) | 2021-02-26 |
| WO2019241789A1 (en) | 2019-12-19 |
| CN112423843B (en) | 2023-11-28 |
| CA3103282A1 (en) | 2019-12-19 |
| US20190388401A1 (en) | 2019-12-26 |
| JP2021528396A (en) | 2021-10-21 |
| EP3813946B1 (en) | 2024-05-22 |
| EP4302827A2 (en) | 2024-01-10 |
| EP4302827A3 (en) | 2024-03-13 |
| JP2024012524A (en) | 2024-01-30 |
| BR112020025283A2 (en) | 2021-03-09 |
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