SG11201606080SA - Dihydropyrrolopyridine inhibitors of ror-gamma - Google Patents

Dihydropyrrolopyridine inhibitors of ror-gamma

Info

Publication number
SG11201606080SA
SG11201606080SA SG11201606080SA SG11201606080SA SG11201606080SA SG 11201606080S A SG11201606080S A SG 11201606080SA SG 11201606080S A SG11201606080S A SG 11201606080SA SG 11201606080S A SG11201606080S A SG 11201606080SA SG 11201606080S A SG11201606080S A SG 11201606080SA
Authority
SG
Singapore
Prior art keywords
ror
gamma
dihydropyrrolopyridine
inhibitors
dihydropyrrolopyridine inhibitors
Prior art date
Application number
SG11201606080SA
Inventor
David A Claremon
Lawrence Wayne Dillard
Chengguo Dong
Yi Fan
Lanqi Jia
Zhijie Liu
Stephen D Lotesta
Andrew Marcus
Suresh B Singh
Colin M Tice
Jing Yuan
Wei Zhao
Yajun Zheng
Linghang Zhuang
Original Assignee
Vitae Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201461935162P priority Critical
Priority to US201461970637P priority
Application filed by Vitae Pharmaceuticals Inc filed Critical Vitae Pharmaceuticals Inc
Priority to PCT/US2015/013699 priority patent/WO2015116904A1/en
Publication of SG11201606080SA publication Critical patent/SG11201606080SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S514/00Drug, bio-affecting and body treating compositions
    • Y10S514/826Asthma
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S514/00Drug, bio-affecting and body treating compositions
    • Y10S514/857Dermatitis
SG11201606080SA 2014-02-03 2015-01-30 Dihydropyrrolopyridine inhibitors of ror-gamma SG11201606080SA (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US201461935162P true 2014-02-03 2014-02-03
US201461970637P true 2014-03-26 2014-03-26
PCT/US2015/013699 WO2015116904A1 (en) 2014-02-03 2015-01-30 Dihydropyrrolopyridine inhibitors of ror-gamma

Publications (1)

Publication Number Publication Date
SG11201606080SA true SG11201606080SA (en) 2016-08-30

Family

ID=52544571

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201606080SA SG11201606080SA (en) 2014-02-03 2015-01-30 Dihydropyrrolopyridine inhibitors of ror-gamma

Country Status (23)

Country Link
US (4) US9266886B2 (en)
EP (2) EP3102576B8 (en)
JP (1) JP6466461B2 (en)
KR (1) KR20160115942A (en)
CN (1) CN105940002B (en)
AU (1) AU2015210833B2 (en)
CA (1) CA2938311A1 (en)
CL (1) CL2016001947A1 (en)
DK (1) DK3102576T3 (en)
EA (1) EA031804B1 (en)
ES (1) ES2735099T3 (en)
IL (1) IL246902D0 (en)
LT (1) LT3102576T (en)
MX (1) MX2016010034A (en)
PE (1) PE20161372A1 (en)
PH (1) PH12016501457A1 (en)
PL (1) PL3102576T3 (en)
PT (1) PT3102576T (en)
RS (1) RS59007B1 (en)
SG (1) SG11201606080SA (en)
SI (1) SI3102576T1 (en)
TW (1) TWI658041B (en)
WO (1) WO2015116904A1 (en)

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WO2018214862A1 (en) * 2017-05-23 2018-11-29 江苏恒瑞医药股份有限公司 Spiroformamide derivative, preparation method therefor, and application thereof for use in pharmaceuticals
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