ATE511508T1 - Verfahren zur kristallisation von (r)- oder (s)- lansoprazol - Google Patents
Verfahren zur kristallisation von (r)- oder (s)- lansoprazolInfo
- Publication number
- ATE511508T1 ATE511508T1 AT01998545T AT01998545T ATE511508T1 AT E511508 T1 ATE511508 T1 AT E511508T1 AT 01998545 T AT01998545 T AT 01998545T AT 01998545 T AT01998545 T AT 01998545T AT E511508 T1 ATE511508 T1 AT E511508T1
- Authority
- AT
- Austria
- Prior art keywords
- lansoprazole
- crystallization
- crystal
- production method
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000367757 | 2000-12-01 | ||
PCT/JP2001/010462 WO2002044167A1 (en) | 2000-12-01 | 2001-11-30 | Process for the crystallization of (r)- or (s)-lansoprazole |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE511508T1 true ATE511508T1 (de) | 2011-06-15 |
Family
ID=18838123
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01998545T ATE511508T1 (de) | 2000-12-01 | 2001-11-30 | Verfahren zur kristallisation von (r)- oder (s)- lansoprazol |
Country Status (17)
Country | Link |
---|---|
US (2) | US7285668B2 (de) |
EP (2) | EP2345650A1 (de) |
KR (3) | KR100887912B1 (de) |
CN (1) | CN1254473C (de) |
AT (1) | ATE511508T1 (de) |
AU (1) | AU2002218506A1 (de) |
CA (1) | CA2436825C (de) |
CY (1) | CY1112347T1 (de) |
DK (1) | DK1337525T3 (de) |
ES (1) | ES2367419T3 (de) |
HK (1) | HK1054380B (de) |
HU (1) | HU229356B1 (de) |
NO (1) | NO326019B1 (de) |
PL (3) | PL399787A1 (de) |
PT (1) | PT1337525E (de) |
TW (1) | TWI290922B (de) |
WO (1) | WO2002044167A1 (de) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020027315A1 (en) * | 2000-03-10 | 2002-03-07 | Parker Gerard E. | Low-firing temperature method for producing Al2O3 bodies having enhanced chemical resistance |
ES2511774T3 (es) | 2000-05-15 | 2014-10-23 | Takeda Pharmaceutical Company Limited | Formas cristalinas de (R)-lansoprazol |
JP2005533755A (ja) * | 2002-03-27 | 2005-11-10 | テバ ファーマシューティカル インダストリーズ リミティド | ランソプラゾール多形及びその調製方法 |
CA2771725C (en) * | 2002-10-16 | 2015-08-18 | Takeda Pharmaceutical Company Limited | Solid preparation comprising a non-toxic base and a proton pump inhibitor |
CA2514575A1 (en) * | 2003-01-31 | 2004-08-12 | Teijin Pharma Limited | Crystal of (23s)-1.alpha.-hydroxy-27-nor-25-methylenevitamin d3-26,23-lactone and process for producing the same |
US20050220870A1 (en) * | 2003-02-20 | 2005-10-06 | Bonnie Hepburn | Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid |
US20050031700A1 (en) * | 2003-07-18 | 2005-02-10 | Sanatarus, Inc. | Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders |
US8993599B2 (en) * | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
AR045062A1 (es) * | 2003-07-18 | 2005-10-12 | Santarus Inc | Formulaciones farmaceuticas para inhibir la secrecion de acido y metodos para preparar y utilizarlas |
US20070292498A1 (en) * | 2003-11-05 | 2007-12-20 | Warren Hall | Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers |
CA2554271A1 (en) * | 2004-02-10 | 2005-08-25 | Santarus, Inc. | Combination of proton pump inhibitor, buffering agent, and nonsteroidal anti-inflammatory agent |
MXPA06011820A (es) * | 2004-04-16 | 2006-12-15 | Santarus Inc | Combinacion de inhibidor de bomba de proton, agente regulador del ph y agente procinetico. |
US8815916B2 (en) * | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8906940B2 (en) * | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
JP5563735B2 (ja) | 2004-06-16 | 2014-07-30 | タケダ ファーマシューティカルズ ユー.エス.エー. インコーポレイティド | Ppi多回剤形 |
EP1681056A1 (de) | 2005-01-14 | 2006-07-19 | Krka Tovarna Zdravil, D.D., Novo Mesto | Verfahren zur Herstellung von Lansoprazol |
BRPI0617987A2 (pt) * | 2005-10-06 | 2011-08-16 | Auspex Pharmaceuticals Inc | composição, composição farmacêutica, forma de dosagem efervescente, composição farmacêutica oral de comprimidos unitários múltiplos, forma de dosagem farmacêutica de liberação prolongada, forma de dosagem farmacêutica revestida entérica, forma de dosagem farmacêutica estável para administração oral a sujeitos mamìferos, método para tratamento de doenças relacionadas a ácido gástrico pela inibição de secreção de ácido gástrico, método para tratamento de uma infecção bacteriana provocada ou mediada por helicobacter pylori, processo para preparar um composto da fórmula 3, processo para preparar um composto da fórmula 5, uso de um composto da fórmula 1 para a preparação de um medicamento para tratamento de doenças relacionadas a ácido gástrico, pela inibição de secreção de ácido gástrico, uso de um composto da fórmula 1 para a preparação de um medicamento para tratamento de uma infecção bacteriana provocada ou mediada por helicobacter pylori uso de um composto da fórmula 1 para a preparação de um medicamento para tratamento de doenças relecionadas a ácido gástrico pela inibição de secreção de ácido gástrico |
CN101389316A (zh) | 2005-12-28 | 2009-03-18 | 武田药品工业株式会社 | 控制释放固体制剂 |
KR100758600B1 (ko) * | 2006-01-05 | 2007-09-13 | 주식회사 대웅제약 | 란소프라졸 결정형 a의 제조방법 |
US20090092658A1 (en) * | 2007-10-05 | 2009-04-09 | Santarus, Inc. | Novel formulations of proton pump inhibitors and methods of using these formulations |
WO2008081891A1 (ja) | 2006-12-28 | 2008-07-10 | Takeda Pharmaceutical Company Limited | 口腔内崩壊性固形製剤 |
WO2008087665A2 (en) * | 2007-01-18 | 2008-07-24 | Matrix Laboratories Ltd | Process for preparation of lansoprazole |
KR101303813B1 (ko) | 2007-04-16 | 2013-09-04 | 에스케이케미칼주식회사 | 라세믹 오메프라졸로부터 에스오메프라졸의 개선된제조방법 |
BRPI0818286A2 (pt) * | 2007-10-12 | 2020-08-11 | Takeda Pharmaceuticals North America, Inc. | métodos de tratamento de distúrbios gastrointestinais independente da ingestão de alimento. |
EP2222663A1 (de) * | 2007-12-18 | 2010-09-01 | Watson Pharma Private Limited | Verfahren zur herstellung von stabilem amorphem r-lansoprazol |
JP2011513202A (ja) * | 2008-03-10 | 2011-04-28 | 武田薬品工業株式会社 | ベンズイミダゾール化合物の結晶 |
NZ589150A (en) | 2008-05-14 | 2012-03-30 | Watson Pharma Private Ltd | Stable r (+) -lansoprazole amine salt and a process for preparing the same |
WO2010039885A2 (en) * | 2008-09-30 | 2010-04-08 | Teva Pharmaceutical Industries Ltd. | Crystalline forms of dexlansoprazole |
KR101321055B1 (ko) * | 2008-11-14 | 2013-10-23 | 한미사이언스 주식회사 | 덱스란소프라졸의 신규 결정형 및 이를 포함하는 약학 조성물 |
IT1391776B1 (it) * | 2008-11-18 | 2012-01-27 | Dipharma Francis Srl | Procedimento per la preparazione di dexlansoprazolo |
WO2010095144A2 (en) * | 2009-02-04 | 2010-08-26 | Msn Laboratories Limited | Process for the preparation of proton pump inhibitors |
IT1392813B1 (it) * | 2009-02-06 | 2012-03-23 | Dipharma Francis Srl | Forme cristalline di dexlansoprazolo |
US20110009637A1 (en) * | 2009-02-10 | 2011-01-13 | Dario Braga | Crystals of Dexlansoprazole |
WO2011004387A2 (en) * | 2009-06-18 | 2011-01-13 | Matrix Laboratories Ltd | Process for the preparation of dexlansoprazole polymorphic forms |
IT1395118B1 (it) * | 2009-07-29 | 2012-09-05 | Dipharma Francis Srl | Procedimento per la preparazione di dexlansoprazolo cristallino |
AU2011210328A1 (en) | 2010-01-29 | 2012-08-16 | Ranbaxy Laboratories Limited | Process for the preparation of crystalline forms of dexlansoprazole |
AU2011234001B2 (en) | 2010-03-31 | 2014-08-28 | Sun Pharmaceutical Industries Limited | Salts of dexlansoprazole and their preparation |
US8853411B2 (en) | 2010-03-31 | 2014-10-07 | Ranbaxy Laboratories Limited | Process for the preparation of dexlansoprazole |
WO2012001705A2 (en) | 2010-06-29 | 2012-01-05 | Cadila Healthcare Limited | Pharmaceutical compositions of (r)-lansoprazole |
CA2819460C (en) | 2010-12-03 | 2017-08-01 | Takeda Pharmaceutical Company Limited | Orally disintegrating tablet |
SG10201602311XA (en) | 2010-12-27 | 2016-04-28 | Takeda Pharmaceutical | Orally disintegrating tablet |
WO2012104805A1 (en) | 2011-02-01 | 2012-08-09 | Ranbaxy Laboratories Limited | Process for the preparation of dexlansoprazole |
US20140357870A1 (en) | 2011-06-21 | 2014-12-04 | Ranbaxy Laboratories Limited | Process for the preparation of dexlansoprazole |
CN102234265B (zh) * | 2011-08-08 | 2013-11-20 | 天津市汉康医药生物技术有限公司 | 兰索拉唑化合物 |
ES2561098T3 (es) | 2011-11-30 | 2016-02-24 | Takeda Pharmaceutical Company Limited | Comprimido recubierto en seco |
US9626793B2 (en) | 2011-12-29 | 2017-04-18 | Intel Corporation | Variable depth compression |
WO2013140120A1 (en) | 2012-03-22 | 2013-09-26 | Cipla Limited | Glycerol solvate forms of (r) - 2 - [ [ [3 -methyl -4 (2,2, 2 - trifluoroethoxy) pyridin- 2 - yl] methyl] sulphinyl] - 1h - ben zimidazole |
WO2013179194A1 (en) | 2012-05-31 | 2013-12-05 | Ranbaxy Laboratories Limited | Process for the preparation of crystalline dexlansoprazole |
MY184077A (en) | 2013-05-21 | 2021-03-17 | Takeda Pharmaceuticals Co | Orally disintegrable tablet |
CN103254174B (zh) * | 2013-06-05 | 2014-06-11 | 湖北济生医药有限公司 | 一种兰索拉唑化合物及其药物组合物 |
JP6557946B2 (ja) | 2013-06-20 | 2019-08-14 | 日本ポリプロ株式会社 | プロピレン系ブロック共重合体 |
CN104958276A (zh) * | 2015-07-30 | 2015-10-07 | 青岛蓝盛洋医药生物科技有限责任公司 | 一种治疗胃溃疡的药物兰索拉唑组合物胶囊 |
CN104997739A (zh) * | 2015-08-31 | 2015-10-28 | 青岛蓝盛洋医药生物科技有限责任公司 | 一种治疗消化系统疾病的药物兰索拉唑组合物冻干粉针剂 |
CN105399728B (zh) * | 2015-12-20 | 2017-11-28 | 寿光富康制药有限公司 | 一种适用于工业化生产的右兰索拉唑的处理方法 |
CN106279107A (zh) * | 2016-08-10 | 2017-01-04 | 成都尚药科技有限公司 | 一种右旋兰索拉唑晶型的制备方法 |
CN106749182A (zh) * | 2016-11-08 | 2017-05-31 | 山东裕欣药业有限公司 | 一种右旋兰索拉唑晶型化合物及其制备方法 |
IT201700050223A1 (it) | 2017-05-09 | 2018-11-09 | Dipharma Francis Srl | Procedimento per la preparazione di dexlansoprazolo cristallino |
WO2024075017A1 (en) | 2022-10-04 | 2024-04-11 | Zabirnyk Arsenii | Inhibition of aortic valve calcification |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6150978A (ja) | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
DK171989B1 (da) * | 1987-08-04 | 1997-09-08 | Takeda Chemical Industries Ltd | Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler |
SE504459C2 (sv) | 1994-07-15 | 1997-02-17 | Astra Ab | Förfarande för framställning av substituerade sulfoxider |
HRP960232A2 (en) | 1995-07-03 | 1998-02-28 | Astra Ab | A process for the optical purification of compounds |
JPH1085502A (ja) * | 1996-09-19 | 1998-04-07 | Konica Corp | 晶析方法 |
TW385306B (en) | 1996-11-14 | 2000-03-21 | Takeda Chemical Industries Ltd | Method for producing crystals of benzimidazole derivatives |
JP3828648B2 (ja) | 1996-11-14 | 2006-10-04 | 武田薬品工業株式会社 | 2−(2−ピリジルメチルスルフィニル)ベンズイミダゾール系化合物の結晶およびその製造法 |
TR199901101T2 (xx) * | 1996-11-22 | 1999-07-21 | The Procter & Gamble Company | Gastroenstentinal hastal�klar�n tedavisine y�nelik bizmut ve nsaid i�eren bile�imler. |
WO1999038512A1 (en) * | 1998-01-30 | 1999-08-05 | Sepracor Inc. | S-lansoprazole compositions and methods |
TWI289557B (en) * | 1999-06-17 | 2007-11-11 | Takeda Chemical Industries Ltd | A crystal of a hydrate of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole |
JP4536905B2 (ja) * | 1999-06-17 | 2010-09-01 | 武田薬品工業株式会社 | ベンズイミダゾール化合物の結晶 |
JP3283252B2 (ja) * | 1999-06-17 | 2002-05-20 | 武田薬品工業株式会社 | ベンズイミダゾール化合物の結晶 |
AU5705700A (en) * | 1999-06-30 | 2001-01-22 | Takeda Chemical Industries Ltd. | Crystals of benzimidazole compounds |
JP2001039975A (ja) * | 1999-07-26 | 2001-02-13 | Eisai Co Ltd | スルホキシド誘導体の結晶およびその製造法 |
WO2001014366A1 (fr) | 1999-08-25 | 2001-03-01 | Takeda Chemical Industries, Ltd. | Procede de preparation de derives optiquement actifs de sulfoxyde |
EP1277752B1 (de) | 2000-04-28 | 2006-11-22 | Takeda Pharmaceutical Company Limited | Verfahren zur herstellung von optisch-aktiven sulfoxid-derivaten |
ES2511774T3 (es) | 2000-05-15 | 2014-10-23 | Takeda Pharmaceutical Company Limited | Formas cristalinas de (R)-lansoprazol |
CN1117747C (zh) * | 2000-06-19 | 2003-08-13 | 中国科学院成都有机化学研究所 | 光学纯兰索拉唑的制备方法 |
-
2001
- 2001-11-30 TW TW090129629A patent/TWI290922B/zh not_active IP Right Cessation
- 2001-11-30 EP EP10177469A patent/EP2345650A1/de not_active Ceased
- 2001-11-30 DK DK01998545.6T patent/DK1337525T3/da active
- 2001-11-30 PL PL399787A patent/PL399787A1/pl unknown
- 2001-11-30 AU AU2002218506A patent/AU2002218506A1/en not_active Abandoned
- 2001-11-30 KR KR1020037007334A patent/KR100887912B1/ko active IP Right Grant
- 2001-11-30 EP EP01998545A patent/EP1337525B8/de not_active Expired - Lifetime
- 2001-11-30 KR KR1020087028441A patent/KR100939948B1/ko active IP Right Grant
- 2001-11-30 HU HU0400781A patent/HU229356B1/hu unknown
- 2001-11-30 CA CA2436825A patent/CA2436825C/en not_active Expired - Lifetime
- 2001-11-30 KR KR1020097023619A patent/KR20100002278A/ko not_active Application Discontinuation
- 2001-11-30 CN CNB018198163A patent/CN1254473C/zh not_active Expired - Lifetime
- 2001-11-30 PL PL409463A patent/PL409463A1/pl unknown
- 2001-11-30 PT PT01998545T patent/PT1337525E/pt unknown
- 2001-11-30 PL PL362801A patent/PL214684B1/pl unknown
- 2001-11-30 AT AT01998545T patent/ATE511508T1/de active
- 2001-11-30 ES ES01998545T patent/ES2367419T3/es not_active Expired - Lifetime
- 2001-11-30 US US10/432,798 patent/US7285668B2/en not_active Expired - Lifetime
- 2001-11-30 WO PCT/JP2001/010462 patent/WO2002044167A1/en not_active Application Discontinuation
-
2003
- 2003-05-28 NO NO20032437A patent/NO326019B1/no not_active IP Right Cessation
- 2003-09-13 HK HK03106568.6A patent/HK1054380B/zh not_active IP Right Cessation
-
2007
- 2007-09-07 US US11/899,918 patent/US20080306118A1/en not_active Abandoned
-
2011
- 2011-08-24 CY CY20111100809T patent/CY1112347T1/el unknown
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