ATE246692T1 - Verfahren zur reinigung von phosphatidylserin - Google Patents
Verfahren zur reinigung von phosphatidylserinInfo
- Publication number
- ATE246692T1 ATE246692T1 AT01124577T AT01124577T ATE246692T1 AT E246692 T1 ATE246692 T1 AT E246692T1 AT 01124577 T AT01124577 T AT 01124577T AT 01124577 T AT01124577 T AT 01124577T AT E246692 T1 ATE246692 T1 AT E246692T1
- Authority
- AT
- Austria
- Prior art keywords
- phosphatidylserine
- purifying
- purifying phosphatidylserine
- phosphatidylation
- phospholipase
- Prior art date
Links
- TZCPCKNHXULUIY-RGULYWFUSA-N 1,2-distearoyl-sn-glycero-3-phosphoserine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC TZCPCKNHXULUIY-RGULYWFUSA-N 0.000 title abstract 2
- ZWZWYGMENQVNFU-UHFFFAOYSA-N Glycerophosphorylserin Natural products OC(=O)C(N)COP(O)(=O)OCC(O)CO ZWZWYGMENQVNFU-UHFFFAOYSA-N 0.000 title abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- 150000002433 hydrophilic molecules Chemical class 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
- C07F9/103—Extraction or purification by physical or chemical treatment of natural phosphatides; Preparation of compositions containing phosphatides of unknown structure
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2000MI002631A IT1319679B1 (it) | 2000-12-05 | 2000-12-05 | Processo di purificazione di fosfatidilserina. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE246692T1 true ATE246692T1 (de) | 2003-08-15 |
Family
ID=11446181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01124577T ATE246692T1 (de) | 2000-12-05 | 2001-10-15 | Verfahren zur reinigung von phosphatidylserin |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6645742B2 (de) |
| EP (1) | EP1213294B2 (de) |
| JP (1) | JP4156228B2 (de) |
| AT (1) | ATE246692T1 (de) |
| DE (1) | DE60100565T3 (de) |
| DK (1) | DK1213294T3 (de) |
| ES (1) | ES2203572T5 (de) |
| IT (1) | IT1319679B1 (de) |
| PT (1) | PT1213294E (de) |
| SI (1) | SI1213294T1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1319679B1 (it) | 2000-12-05 | 2003-10-23 | Chemi Spa | Processo di purificazione di fosfatidilserina. |
| US6878532B1 (en) | 2003-04-28 | 2005-04-12 | Sioux Biochemical, Inc. | Method of producing phosphatidylserine |
| IL158139A0 (en) | 2003-09-25 | 2004-09-27 | Enzymotec Ltd | Stabilized formulations of phosphatidyl serine |
| US7935365B2 (en) * | 2003-10-22 | 2011-05-03 | Enzymotec, Ltd. | Glycerophospholipids for the improvement of cognitive functions |
| US20050130937A1 (en) | 2003-10-22 | 2005-06-16 | Enzymotec Ltd. | Lipids containing omega-3 and omega-6 fatty acids |
| US8052992B2 (en) | 2003-10-22 | 2011-11-08 | Enzymotec Ltd. | Glycerophospholipids containing omega-3 and omega-6 fatty acids and their use in the treatment and improvement of cognitive functions |
| EP1739183A4 (de) * | 2004-03-18 | 2010-10-13 | Nagase Chemtex Corp | Verfahren zur enzymentfernung sowie verfahren zum basenaustausch oder zur hydrolyse von phospholipid unter verwendung davon |
| US7465717B2 (en) * | 2004-09-27 | 2008-12-16 | Soymor | Process for releasing and extracting phosphatides from a phosphatide-containing matrix |
| ITPD20050164A1 (it) | 2005-05-30 | 2006-11-30 | Fidia Farmaceutici | Processo per la preparazione e l'isolamento di fosfatidi |
| JP4887674B2 (ja) * | 2005-07-07 | 2012-02-29 | ナガセケムテックス株式会社 | リン脂質組成物の製造方法 |
| JP4931527B2 (ja) * | 2006-09-20 | 2012-05-16 | 富士フイルム株式会社 | フッ素化ホスファチジルセリン化合物 |
| JP5894377B2 (ja) * | 2011-06-03 | 2016-03-30 | 株式会社カネカ | リン脂質の製造方法 |
| CN103074390A (zh) * | 2011-11-02 | 2013-05-01 | 江南大学 | 一种酶法制备不含溶血磷脂和磷脂酸的磷脂酰丙醇的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1504125A (en) | 1974-03-22 | 1978-03-15 | Unilever Ltd | Process for purifying phosphatides |
| US5084215A (en) * | 1984-02-13 | 1992-01-28 | The Liposome Company, Inc. | Process for purification of phospholipids |
| JPS6336790A (ja) | 1986-08-01 | 1988-02-17 | Nippon Oil & Fats Co Ltd | リン脂質の塩基交換反応法 |
| JP2987682B2 (ja) | 1995-06-19 | 1999-12-06 | 花王株式会社 | 酸性リン脂質の濃縮法 |
| US5700668A (en) * | 1995-12-08 | 1997-12-23 | Italfarmaco Sud S.P.A. | Process for the industrial preparation of phosphatidylserine |
| DE19917249C2 (de) * | 1999-02-26 | 2001-09-27 | Meyer Lucas Gmbh & Co | Verfahren zur Herstellung von Phosphatidylserin-Produkten |
| IT1311929B1 (it) * | 1999-04-28 | 2002-03-20 | Chemi Spa | Procedimento per la preparazione di fosfatidilserine. |
| IT1319679B1 (it) | 2000-12-05 | 2003-10-23 | Chemi Spa | Processo di purificazione di fosfatidilserina. |
-
2000
- 2000-12-05 IT IT2000MI002631A patent/IT1319679B1/it active
-
2001
- 2001-10-15 ES ES01124577T patent/ES2203572T5/es not_active Expired - Lifetime
- 2001-10-15 DK DK01124577T patent/DK1213294T3/da active
- 2001-10-15 SI SI200130023T patent/SI1213294T1/xx unknown
- 2001-10-15 AT AT01124577T patent/ATE246692T1/de not_active IP Right Cessation
- 2001-10-15 PT PT01124577T patent/PT1213294E/pt unknown
- 2001-10-15 EP EP01124577A patent/EP1213294B2/de not_active Expired - Lifetime
- 2001-10-15 DE DE60100565T patent/DE60100565T3/de not_active Expired - Lifetime
- 2001-10-18 US US09/982,468 patent/US6645742B2/en not_active Ceased
- 2001-11-08 JP JP2001342776A patent/JP4156228B2/ja not_active Expired - Lifetime
-
2011
- 2011-06-24 US US13/167,785 patent/USRE43764E1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE60100565T3 (de) | 2009-04-23 |
| JP2002193982A (ja) | 2002-07-10 |
| EP1213294B1 (de) | 2003-08-06 |
| PT1213294E (pt) | 2003-12-31 |
| ES2203572T3 (es) | 2004-04-16 |
| IT1319679B1 (it) | 2003-10-23 |
| EP1213294A1 (de) | 2002-06-12 |
| USRE43764E1 (en) | 2012-10-23 |
| DE60100565T2 (de) | 2004-03-25 |
| DE60100565D1 (de) | 2003-09-11 |
| SI1213294T1 (en) | 2003-12-31 |
| DK1213294T3 (da) | 2003-11-17 |
| JP4156228B2 (ja) | 2008-09-24 |
| ES2203572T5 (es) | 2009-03-01 |
| US6645742B2 (en) | 2003-11-11 |
| EP1213294B2 (de) | 2008-10-22 |
| US20020103393A1 (en) | 2002-08-01 |
| ITMI20002631A1 (it) | 2002-06-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1213294 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |