DE60316791D1 - Verfahren zur aufreinigung von lanzoprazol - Google Patents

Verfahren zur aufreinigung von lanzoprazol

Info

Publication number
DE60316791D1
DE60316791D1 DE60316791T DE60316791T DE60316791D1 DE 60316791 D1 DE60316791 D1 DE 60316791D1 DE 60316791 T DE60316791 T DE 60316791T DE 60316791 T DE60316791 T DE 60316791T DE 60316791 D1 DE60316791 D1 DE 60316791D1
Authority
DE
Germany
Prior art keywords
lanzoprazole
purifying
lansoprazole
provides
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60316791T
Other languages
English (en)
Other versions
DE60316791T2 (de
Inventor
Claude Singer
Anita Liberman
Irena Veinberg
Nina Finklestein
Tamar Nidam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Industries Ltd
Original Assignee
Teva Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd filed Critical Teva Pharmaceutical Industries Ltd
Application granted granted Critical
Publication of DE60316791D1 publication Critical patent/DE60316791D1/de
Publication of DE60316791T2 publication Critical patent/DE60316791T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
DE60316791T 2002-08-21 2003-08-21 Verfahren zur aufreinigung von lanzoprazol Expired - Lifetime DE60316791T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US40484502P 2002-08-21 2002-08-21
US404845P 2002-08-21
US41805602P 2002-10-11 2002-10-11
US418056P 2002-10-11
PCT/US2003/026544 WO2004018454A1 (en) 2002-08-21 2003-08-21 A method for the purification of lansoprazole

Publications (2)

Publication Number Publication Date
DE60316791D1 true DE60316791D1 (de) 2007-11-22
DE60316791T2 DE60316791T2 (de) 2008-07-24

Family

ID=31949873

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60316791T Expired - Lifetime DE60316791T2 (de) 2002-08-21 2003-08-21 Verfahren zur aufreinigung von lanzoprazol

Country Status (10)

Country Link
US (4) US6909004B2 (de)
EP (1) EP1501824B1 (de)
JP (2) JP2006500380A (de)
AT (1) ATE375338T1 (de)
AU (1) AU2003258335A1 (de)
DE (1) DE60316791T2 (de)
ES (1) ES2294358T3 (de)
IL (1) IL166985A (de)
PT (1) PT1501824E (de)
WO (1) WO2004018454A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2237354T3 (es) 2002-11-18 2007-11-01 Teva Pharmaceutical Industries Ltd. Lansoprazol estable que contiene mas de 500 ppm, hasta aproximadamente 3.000 ppm de agua y mas de 200 ppm, hasta aproximadamente 5.000 ppm de alcohol.
CA2515130A1 (en) * 2003-02-05 2004-08-26 Teva Pharmaceutical Industries Ltd. Method of stabilizing lansoprazole
US7491732B2 (en) * 2005-06-08 2009-02-17 Rigel Pharmaceuticals, Inc. Compositions and methods for inhibition of the JAK pathway
KR100758600B1 (ko) 2006-01-05 2007-09-13 주식회사 대웅제약 란소프라졸 결정형 ａ의 제조방법
WO2008035189A1 (en) * 2006-09-22 2008-03-27 Orchid Chemicals & Pharmaceuticals Limited A method for the purification of lansoprazole
WO2008087665A2 (en) * 2007-01-18 2008-07-24 Matrix Laboratories Ltd Process for preparation of lansoprazole
WO2010117756A2 (en) * 2009-03-31 2010-10-14 Dr. Reddy's Laboratories Ltd Substituted benzimidazole pharmaceutical formulations
WO2010146428A1 (en) * 2009-06-15 2010-12-23 Orchid Chemicals And Pharmaceuticals Ltd. An improved process for the preparation of rabeprazole
WO2011121548A1 (en) * 2010-03-31 2011-10-06 Ranbaxy Laboratories Limited Process for the preparation of dexlansoprazole
CN103012369B (zh) * 2011-05-23 2014-04-23 中山大学 兰索拉唑n晶型及其制备方法和应用
CN102180866B (zh) * 2011-05-23 2013-03-13 中山大学 兰索拉唑晶型及其制备方法和应用
US20140357870A1 (en) * 2011-06-21 2014-12-04 Ranbaxy Laboratories Limited Process for the preparation of dexlansoprazole
CN109265442A (zh) * 2018-10-12 2019-01-25 河南精康制药有限公司 一种原料药兰索拉唑的精制方法
CN112834627B (zh) * 2019-11-22 2022-05-20 扬子江药业集团有限公司 高效液相色谱法分离测定注射用兰索拉唑有关物质的方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
CA1327010C (en) 1986-02-13 1994-02-15 Tadashi Makino Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production
US5433959A (en) 1986-02-13 1995-07-18 Takeda Chemical Industries, Ltd. Stabilized pharmaceutical composition
US5026560A (en) 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
DK171989B1 (da) * 1987-08-04 1997-09-08 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler
ES2036948B1 (es) 1991-11-21 1994-09-01 Genesis Para La Investigacion Procedimiento de obtencion de compuestos derivados de piridina.
ES2063705B1 (es) 1993-06-14 1995-07-16 S A L V A T Lab Sa Intermedio para la sintesis de lansoprazol y su procedimiento de obtencion.
TW385306B (en) * 1996-11-14 2000-03-21 Takeda Chemical Industries Ltd Method for producing crystals of benzimidazole derivatives
CN1169807C (zh) 1997-07-11 2004-10-06 卫材株式会社 制备吡啶衍生物的方法
GB9805558D0 (en) 1998-03-17 1998-05-13 Knoll Ag Chemical process`
SI20019A (sl) * 1998-07-13 2000-02-29 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola
US6166213A (en) * 1998-08-11 2000-12-26 Merck & Co., Inc. Omeprazole process and compositions thereof
JP3926936B2 (ja) 1998-11-16 2007-06-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホキシド誘導体・アセトン錯体およびその製造法
KR100362947B1 (ko) 1999-09-21 2002-11-30 주식회사 대웅 설폭시드 화합물의 제조방법
ES2163372B1 (es) 2000-03-13 2003-05-01 Esteve Quimica Sa Procedimiento de oxidacion de un grupo tioeter a sulfoxido.
US20040138466A1 (en) * 2001-02-02 2004-07-15 Ilya Avrutov Processes for the production of substituted 2-(2-pyridylmethyl) sulfinyl-1H-benzimidazoles
WO2002062786A1 (en) * 2001-02-02 2002-08-15 Teva Pharmaceutical Industries Ltd. Processes for the production of substituted 2-(2-pyridylmethyl) sulfinyl-1h-benzimidazoles

Also Published As

Publication number Publication date
US6909004B2 (en) 2005-06-21
US20050165061A1 (en) 2005-07-28
EP1501824B1 (de) 2007-10-10
JP2010083897A (ja) 2010-04-15
US7022859B2 (en) 2006-04-04
US7622588B2 (en) 2009-11-24
ES2294358T3 (es) 2008-04-01
US20050165059A1 (en) 2005-07-28
ATE375338T1 (de) 2007-10-15
AU2003258335A1 (en) 2004-03-11
US20050165060A1 (en) 2005-07-28
US7060837B2 (en) 2006-06-13
US20040192923A1 (en) 2004-09-30
DE60316791T2 (de) 2008-07-24
IL166985A (en) 2010-04-15
PT1501824E (pt) 2007-11-28
JP2006500380A (ja) 2006-01-05
WO2004018454A1 (en) 2004-03-04
WO2004018454A8 (en) 2005-03-31
EP1501824A1 (de) 2005-02-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition