ATE496038T1 - Verfahren zur herstellung von quetiapin - Google Patents
Verfahren zur herstellung von quetiapinInfo
- Publication number
- ATE496038T1 ATE496038T1 AT04767075T AT04767075T ATE496038T1 AT E496038 T1 ATE496038 T1 AT E496038T1 AT 04767075 T AT04767075 T AT 04767075T AT 04767075 T AT04767075 T AT 04767075T AT E496038 T1 ATE496038 T1 AT E496038T1
- Authority
- AT
- Austria
- Prior art keywords
- quetiapine
- producing
- producing quetiapine
- deprotection
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D281/16—[b, f]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50498203P | 2003-09-23 | 2003-09-23 | |
| PCT/FI2004/000561 WO2005028459A1 (en) | 2003-09-23 | 2004-09-23 | Preparation method for quetiapine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE496038T1 true ATE496038T1 (de) | 2011-02-15 |
Family
ID=34375549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04767075T ATE496038T1 (de) | 2003-09-23 | 2004-09-23 | Verfahren zur herstellung von quetiapin |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7858777B2 (de) |
| EP (1) | EP1664009B1 (de) |
| JP (1) | JP2007505865A (de) |
| AT (1) | ATE496038T1 (de) |
| CA (1) | CA2538866A1 (de) |
| DE (1) | DE602004031129D1 (de) |
| WO (1) | WO2005028459A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL164155A0 (en) * | 2002-03-20 | 2005-12-18 | Teva Pharma | Crystalline forms of quetiapine hemifumarate |
| JP2007505864A (ja) * | 2003-09-23 | 2007-03-15 | フェルミオン オサケ ユキチュア | クエチアピンの製造 |
| WO2006113425A1 (en) | 2005-04-14 | 2006-10-26 | Teva Pharmaceutical Industries Ltd. | Process for preparing quetiapine fumarate |
| EP2144892A2 (de) * | 2007-03-29 | 2010-01-20 | Teva Pharmaceutical Industries Ltd. | Verbessertes verfahren zur herstellung von quetiapinfumaraten |
| WO2009004480A2 (en) | 2007-05-07 | 2009-01-08 | Actavis Group Ptc Ehf | Quetiapine salts and their polymorphs |
| US8420807B2 (en) | 2008-01-31 | 2013-04-16 | Fermion Oy | Process for the preparation of quetiapine |
| EP2403841A1 (de) | 2009-03-04 | 2012-01-11 | Ranbaxy Laboratories Limited | Verfahren zur herstellung von quetiapinfumarat |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA979441A (en) * | 1967-02-27 | 1975-12-09 | American Cyanamid Company | 11-(piperazinyl) dibenz (b,f) (1,4) oxazepines and analogous thiazepines |
| US3539573A (en) | 1967-03-22 | 1970-11-10 | Jean Schmutz | 11-basic substituted dibenzodiazepines and dibenzothiazepines |
| US3458516A (en) * | 1968-02-16 | 1969-07-29 | American Cyanamid Co | 11-(piperazinyl)dibenz(b,f)(1,4)oxazepines and analogous thiazepines |
| GB8607684D0 (en) * | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
| GB8705574D0 (en) * | 1987-03-10 | 1987-04-15 | Ici Plc | Preparation of thiazepine compound |
| HU227039B1 (en) * | 2000-01-25 | 2010-05-28 | Egis Gyogyszergyar Nyilvanosan | New process for the production of quetiapine and intermediates therefor |
| JP2007505864A (ja) | 2003-09-23 | 2007-03-15 | フェルミオン オサケ ユキチュア | クエチアピンの製造 |
-
2004
- 2004-09-23 CA CA002538866A patent/CA2538866A1/en not_active Abandoned
- 2004-09-23 DE DE602004031129T patent/DE602004031129D1/de active Active
- 2004-09-23 AT AT04767075T patent/ATE496038T1/de not_active IP Right Cessation
- 2004-09-23 WO PCT/FI2004/000561 patent/WO2005028459A1/en active Application Filing
- 2004-09-23 US US10/572,370 patent/US7858777B2/en not_active Expired - Fee Related
- 2004-09-23 EP EP04767075A patent/EP1664009B1/de active Active
- 2004-09-23 JP JP2006526654A patent/JP2007505865A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US7858777B2 (en) | 2010-12-28 |
| EP1664009A1 (de) | 2006-06-07 |
| US20070111986A1 (en) | 2007-05-17 |
| EP1664009B1 (de) | 2011-01-19 |
| JP2007505865A (ja) | 2007-03-15 |
| DE602004031129D1 (de) | 2011-03-03 |
| CA2538866A1 (en) | 2005-03-31 |
| WO2005028459A1 (en) | 2005-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |