ATE375338T1 - Verfahren zur aufreinigung von lanzoprazol - Google Patents
Verfahren zur aufreinigung von lanzoprazolInfo
- Publication number
- ATE375338T1 ATE375338T1 AT03793375T AT03793375T ATE375338T1 AT E375338 T1 ATE375338 T1 AT E375338T1 AT 03793375 T AT03793375 T AT 03793375T AT 03793375 T AT03793375 T AT 03793375T AT E375338 T1 ATE375338 T1 AT E375338T1
- Authority
- AT
- Austria
- Prior art keywords
- lanzoprazole
- purification
- lansoprazole
- provides
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40484502P | 2002-08-21 | 2002-08-21 | |
US41805602P | 2002-10-11 | 2002-10-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE375338T1 true ATE375338T1 (de) | 2007-10-15 |
Family
ID=31949873
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03793375T ATE375338T1 (de) | 2002-08-21 | 2003-08-21 | Verfahren zur aufreinigung von lanzoprazol |
Country Status (10)
Country | Link |
---|---|
US (4) | US6909004B2 (de) |
EP (1) | EP1501824B1 (de) |
JP (2) | JP2006500380A (de) |
AT (1) | ATE375338T1 (de) |
AU (1) | AU2003258335A1 (de) |
DE (1) | DE60316791T2 (de) |
ES (1) | ES2294358T3 (de) |
IL (1) | IL166985A (de) |
PT (1) | PT1501824E (de) |
WO (1) | WO2004018454A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003294405A1 (en) | 2002-11-18 | 2004-06-15 | Teva Pharmaceutical Industries Ltd. | Stable lansoprazole containing more than 500 ppm, up to about 3,000 ppm water and more than 200 ppm, up to about 5,000 ppm alcohol |
WO2004072061A1 (en) * | 2003-02-05 | 2004-08-26 | Teva Pharmaceutical Industries Ltd. | Method of stabilizing lansoprazole |
WO2006133426A2 (en) * | 2005-06-08 | 2006-12-14 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the jak pathway |
KR100758600B1 (ko) * | 2006-01-05 | 2007-09-13 | 주식회사 대웅제약 | 란소프라졸 결정형 a의 제조방법 |
US8129536B2 (en) | 2006-09-22 | 2012-03-06 | Orchid Chemicals & Pharmaceuticals Limited | Method for the purification of lansoprazole |
WO2008087665A2 (en) * | 2007-01-18 | 2008-07-24 | Matrix Laboratories Ltd | Process for preparation of lansoprazole |
WO2010117756A2 (en) * | 2009-03-31 | 2010-10-14 | Dr. Reddy's Laboratories Ltd | Substituted benzimidazole pharmaceutical formulations |
WO2010146428A1 (en) * | 2009-06-15 | 2010-12-23 | Orchid Chemicals And Pharmaceuticals Ltd. | An improved process for the preparation of rabeprazole |
AU2011234003B2 (en) * | 2010-03-31 | 2013-09-19 | Sun Pharmaceutical Industries Limited | Process for the preparation of dexlansoprazole |
CN103012369B (zh) * | 2011-05-23 | 2014-04-23 | 中山大学 | 兰索拉唑n晶型及其制备方法和应用 |
CN102180866B (zh) * | 2011-05-23 | 2013-03-13 | 中山大学 | 兰索拉唑晶型及其制备方法和应用 |
AU2012274967A1 (en) * | 2011-06-21 | 2014-01-23 | Sun Pharmaceutical Industries Limited | Process for the preparation of dexlansoprazole |
CN109265442A (zh) * | 2018-10-12 | 2019-01-25 | 河南精康制药有限公司 | 一种原料药兰索拉唑的精制方法 |
CN112834627B (zh) * | 2019-11-22 | 2022-05-20 | 扬子江药业集团有限公司 | 高效液相色谱法分离测定注射用兰索拉唑有关物质的方法 |
WO2024075017A1 (en) | 2022-10-04 | 2024-04-11 | Zabirnyk Arsenii | Inhibition of aortic valve calcification |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6150978A (ja) | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
CA1327010C (en) | 1986-02-13 | 1994-02-15 | Tadashi Makino | Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production |
US5433959A (en) | 1986-02-13 | 1995-07-18 | Takeda Chemical Industries, Ltd. | Stabilized pharmaceutical composition |
US5026560A (en) | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
DK171989B1 (da) | 1987-08-04 | 1997-09-08 | Takeda Chemical Industries Ltd | Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler |
ES2036948B1 (es) | 1991-11-21 | 1994-09-01 | Genesis Para La Investigacion | Procedimiento de obtencion de compuestos derivados de piridina. |
ES2063705B1 (es) | 1993-06-14 | 1995-07-16 | S A L V A T Lab Sa | Intermedio para la sintesis de lansoprazol y su procedimiento de obtencion. |
TW385306B (en) | 1996-11-14 | 2000-03-21 | Takeda Chemical Industries Ltd | Method for producing crystals of benzimidazole derivatives |
EP0997461B1 (de) | 1997-07-11 | 2003-05-21 | Eisai Co., Ltd. | Verfahren zur herstellung von pyridinderivaten |
GB9805558D0 (en) | 1998-03-17 | 1998-05-13 | Knoll Ag | Chemical process` |
SI20019A (sl) | 1998-07-13 | 2000-02-29 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola |
US6166213A (en) * | 1998-08-11 | 2000-12-26 | Merck & Co., Inc. | Omeprazole process and compositions thereof |
JP3926936B2 (ja) | 1998-11-16 | 2007-06-06 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | スルホキシド誘導体・アセトン錯体およびその製造法 |
KR100362947B1 (ko) | 1999-09-21 | 2002-11-30 | 주식회사 대웅 | 설폭시드 화합물의 제조방법 |
ES2163372B1 (es) | 2000-03-13 | 2003-05-01 | Esteve Quimica Sa | Procedimiento de oxidacion de un grupo tioeter a sulfoxido. |
YU61103A (sh) * | 2001-02-02 | 2006-05-25 | Teva Pharmaceutical Industries Ltd. | Postupci za produkciju supstituisanih 2-(2-piridilmetil) sulfinil-1h-benzimidazola |
US20040138466A1 (en) * | 2001-02-02 | 2004-07-15 | Ilya Avrutov | Processes for the production of substituted 2-(2-pyridylmethyl) sulfinyl-1H-benzimidazoles |
-
2003
- 2003-08-21 DE DE60316791T patent/DE60316791T2/de not_active Expired - Lifetime
- 2003-08-21 EP EP03793375A patent/EP1501824B1/de not_active Expired - Lifetime
- 2003-08-21 JP JP2004531171A patent/JP2006500380A/ja not_active Withdrawn
- 2003-08-21 PT PT03793375T patent/PT1501824E/pt unknown
- 2003-08-21 WO PCT/US2003/026544 patent/WO2004018454A1/en active IP Right Grant
- 2003-08-21 AU AU2003258335A patent/AU2003258335A1/en not_active Abandoned
- 2003-08-21 ES ES03793375T patent/ES2294358T3/es not_active Expired - Lifetime
- 2003-08-21 AT AT03793375T patent/ATE375338T1/de not_active IP Right Cessation
- 2003-08-21 US US10/646,059 patent/US6909004B2/en not_active Expired - Fee Related
-
2005
- 2005-02-20 IL IL166985A patent/IL166985A/en not_active IP Right Cessation
- 2005-03-18 US US11/083,485 patent/US7622588B2/en not_active Expired - Fee Related
- 2005-03-18 US US11/083,652 patent/US7060837B2/en not_active Expired - Fee Related
- 2005-03-18 US US11/084,269 patent/US7022859B2/en not_active Expired - Fee Related
-
2009
- 2009-12-28 JP JP2009297316A patent/JP2010083897A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US7022859B2 (en) | 2006-04-04 |
US20040192923A1 (en) | 2004-09-30 |
US20050165061A1 (en) | 2005-07-28 |
US20050165059A1 (en) | 2005-07-28 |
US7060837B2 (en) | 2006-06-13 |
DE60316791T2 (de) | 2008-07-24 |
US20050165060A1 (en) | 2005-07-28 |
WO2004018454A1 (en) | 2004-03-04 |
JP2006500380A (ja) | 2006-01-05 |
ES2294358T3 (es) | 2008-04-01 |
DE60316791D1 (de) | 2007-11-22 |
EP1501824B1 (de) | 2007-10-10 |
AU2003258335A1 (en) | 2004-03-11 |
JP2010083897A (ja) | 2010-04-15 |
IL166985A (en) | 2010-04-15 |
US7622588B2 (en) | 2009-11-24 |
US6909004B2 (en) | 2005-06-21 |
PT1501824E (pt) | 2007-11-28 |
WO2004018454A8 (en) | 2005-03-31 |
EP1501824A1 (de) | 2005-02-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |