ATE283865T1 - Peptidanaloga mit inhibitorischer wirkung auf hepatitis c - Google Patents

Peptidanaloga mit inhibitorischer wirkung auf hepatitis c

Info

Publication number
ATE283865T1
ATE283865T1 AT98939997T AT98939997T ATE283865T1 AT E283865 T1 ATE283865 T1 AT E283865T1 AT 98939997 T AT98939997 T AT 98939997T AT 98939997 T AT98939997 T AT 98939997T AT E283865 T1 ATE283865 T1 AT E283865T1
Authority
AT
Austria
Prior art keywords
alkyl
hepatitis
inhibitory effect
carboxy
formula
Prior art date
Application number
AT98939997T
Other languages
German (de)
English (en)
Inventor
Montse Llinas-Brunet
Murray Douglas Bailey
Teddy Halmos
Marc-Andre Poupart
Youla Tsantrizos
Original Assignee
Boehringer Ingelheim Ca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Ca Ltd filed Critical Boehringer Ingelheim Ca Ltd
Application granted granted Critical
Publication of ATE283865T1 publication Critical patent/ATE283865T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT98939997T 1997-08-11 1998-08-10 Peptidanaloga mit inhibitorischer wirkung auf hepatitis c ATE283865T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5524797P 1997-08-11 1997-08-11
PCT/CA1998/000764 WO1999007734A2 (en) 1997-08-11 1998-08-10 Hepatitis c inhibitor peptide analogues

Publications (1)

Publication Number Publication Date
ATE283865T1 true ATE283865T1 (de) 2004-12-15

Family

ID=21996648

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98939997T ATE283865T1 (de) 1997-08-11 1998-08-10 Peptidanaloga mit inhibitorischer wirkung auf hepatitis c

Country Status (13)

Country Link
US (1) US6143715A (https=)
EP (1) EP1012180B1 (https=)
JP (1) JP4452401B2 (https=)
AT (1) ATE283865T1 (https=)
AU (1) AU757072B2 (https=)
CA (1) CA2294562C (https=)
DE (1) DE69827956T2 (https=)
ES (1) ES2234144T3 (https=)
HU (1) HUP0100100A3 (https=)
IL (1) IL134233A0 (https=)
NZ (1) NZ503263A (https=)
PT (1) PT1012180E (https=)
WO (1) WO1999007734A2 (https=)

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JP2001512744A (ja) 2001-08-28
DE69827956D1 (de) 2005-01-05
WO1999007734A2 (en) 1999-02-18
AU8846698A (en) 1999-03-01
IL134233A0 (en) 2001-04-30
CA2294562C (en) 2005-07-26
EP1012180A2 (en) 2000-06-28
EP1012180B1 (en) 2004-12-01
US6143715A (en) 2000-11-07
DE69827956T2 (de) 2005-04-14
CA2294562A1 (en) 1999-02-18
AU757072B2 (en) 2003-01-30
PT1012180E (pt) 2005-04-29
JP4452401B2 (ja) 2010-04-21
NZ503263A (en) 2002-10-25
HUP0100100A3 (en) 2001-12-28
HUP0100100A2 (hu) 2001-11-28
WO1999007734A3 (en) 1999-05-20
ES2234144T3 (es) 2005-06-16

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