ATE266735T1 - Verfahren zur herstellung eines produktes, welches gegen bluthochdruck gerichtete tripeptide enthält - Google Patents

Verfahren zur herstellung eines produktes, welches gegen bluthochdruck gerichtete tripeptide enthält

Info

Publication number
ATE266735T1
ATE266735T1 AT00972941T AT00972941T ATE266735T1 AT E266735 T1 ATE266735 T1 AT E266735T1 AT 00972941 T AT00972941 T AT 00972941T AT 00972941 T AT00972941 T AT 00972941T AT E266735 T1 ATE266735 T1 AT E266735T1
Authority
AT
Austria
Prior art keywords
product
hypertension
directed
producing
tripeptides
Prior art date
Application number
AT00972941T
Other languages
English (en)
Inventor
Olli Tossavainen
Tarja Suomalainen
Janne Sahlstein
Annika Maeyrae-Maekinen
Original Assignee
Valio Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valio Ltd filed Critical Valio Ltd
Application granted granted Critical
Publication of ATE266735T1 publication Critical patent/ATE266735T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/12Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/123Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
    • A23C9/1234Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt characterised by using a Lactobacillus sp. other than Lactobacillus Bulgaricus, including Bificlobacterium sp.
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/14Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/142Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
    • A23C9/1427Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by dialysis, reverse osmosis or hyperfiltration, e.g. for concentrating or desalting
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00Working-up of proteins for foodstuffs
    • A23J3/30Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/341Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
    • A23J3/343Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
    • A23J3/344Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins of casein
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52Adding ingredients
    • A23L2/66Proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/18Peptides; Protein hydrolysates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/11Lactobacillus
    • A23V2400/147Helveticus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225Lactobacillus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Water Supply & Treatment (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AT00972941T 1999-11-01 2000-10-30 Verfahren zur herstellung eines produktes, welches gegen bluthochdruck gerichtete tripeptide enthält ATE266735T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI992360A FI113741B (fi) 1999-11-01 1999-11-01 Menetelmä verenpainetta alentavia peptidejä sisältävän tuotteen valmistamiseksi
PCT/FI2000/000942 WO2001032905A1 (en) 1999-11-01 2000-10-30 Process for producing a product containing antihypertensive tripeptides

Publications (1)

Publication Number Publication Date
ATE266735T1 true ATE266735T1 (de) 2004-05-15

Family

ID=8555541

Family Applications (2)

Application Number Title Priority Date Filing Date
AT00972940T ATE285470T1 (de) 1999-11-01 2000-10-30 Lactobacillus helveticus, welches blutdrucksenkende di- und tripeptide herstellt
AT00972941T ATE266735T1 (de) 1999-11-01 2000-10-30 Verfahren zur herstellung eines produktes, welches gegen bluthochdruck gerichtete tripeptide enthält

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT00972940T ATE285470T1 (de) 1999-11-01 2000-10-30 Lactobacillus helveticus, welches blutdrucksenkende di- und tripeptide herstellt

Country Status (23)

Country Link
US (2) US6890529B1 (de)
EP (2) EP1226267B1 (de)
JP (2) JP3695648B2 (de)
KR (2) KR100718709B1 (de)
CN (2) CN1164761C (de)
AT (2) ATE285470T1 (de)
AU (2) AU769432B2 (de)
CA (2) CA2387738C (de)
CZ (2) CZ294146B6 (de)
DE (2) DE60016959T2 (de)
DK (2) DK1226230T3 (de)
EE (2) EE200200231A (de)
ES (2) ES2234686T3 (de)
FI (1) FI113741B (de)
HR (2) HRP20020377B1 (de)
HU (2) HU226200B1 (de)
NO (2) NO20022062L (de)
NZ (2) NZ518493A (de)
PL (2) PL204119B1 (de)
PT (2) PT1226267E (de)
RU (2) RU2270855C2 (de)
WO (2) WO2001032836A1 (de)
ZA (2) ZA200203179B (de)

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FI112031B (fi) 2002-02-25 2003-10-31 Valio Oy Biologisesti aktiivisen tuotteen uusi käyttö
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WO2004060073A1 (en) * 2003-01-06 2004-07-22 Unilever N.V. Fermented milk product comprising tripeptide vpp and/or ipp
TWI411441B (zh) * 2003-03-18 2013-10-11 Suntory Holdings Ltd 血管收縮素轉化酶抑制性肽類
US7718171B2 (en) 2003-04-07 2010-05-18 Chr. Hansen A/S Reducing heart rate in mammals using milk derived fermentation products produced using Lactobacillus helveticus
AU2004237455B2 (en) 2003-05-05 2007-08-02 Dsm Ip Assets B.V. Hydrolysed casein product comprising tripeptides IPP and/ or VPP
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PT1820849E (pt) * 2006-02-20 2009-04-24 Gervais Danone Sa Novas estirpes de lactobacillus helveticus
DK1820850T3 (da) * 2006-02-20 2009-06-29 Gervais Danone Sa Nye stammer af Lactobacillus Helveticus
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KR101492650B1 (ko) * 2006-09-04 2015-02-12 유키지루시 메그밀크 가부시키가이샤 혈중 아디포넥틴 농도 증가 촉진 및/또는 감소 억제제 및 내장 지방 축적 억제제
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ES2842587T3 (es) 2016-12-02 2021-07-14 Fairlife Llc Leche en polvo sin lactosa y sin pardeamiento y métodos de preparación de la misma
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RU2728171C2 (ru) * 2018-11-08 2020-07-28 Общество с ограниченной ответственностью "Инновационные биотехнологии" (ООО "Инбиотех") Штамм бактерий Lactobacillus helveticus T-5068, используемый в качестве закваски прямого внесения для приготовления кисломолочных продуктов
CN109517763B (zh) * 2018-12-27 2022-03-22 内蒙古农业大学 瑞士乳杆菌h11及其应用
TWI713972B (zh) * 2019-01-14 2020-12-21 大江生醫股份有限公司 改善呼吸道健康之益生菌株及其組合物與用途
AU2021247419A1 (en) * 2020-04-02 2022-11-03 Fatah Bashir AHTESH Milk fermentation process
CN112029784A (zh) * 2020-09-16 2020-12-04 内蒙古农业大学 一个与蛋白水解能力相关的基因及基于该基因的高蛋白水解能力瑞士乳杆菌的筛选方法
KR102684805B1 (ko) 2023-12-20 2024-07-12 푸른하늘환경주식회사 우수 유출수의 정화 처리 장치
KR102687298B1 (ko) 2023-12-20 2024-07-22 푸른하늘환경주식회사 비점오염물질 저감 및 우수 정화 장치
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DE60010742T2 (de) 2005-05-12
HRP20020377B1 (en) 2005-06-30
PL355670A1 (pl) 2004-05-04
KR20020060220A (ko) 2002-07-16
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ZA200203179B (en) 2003-07-22
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