DE60033553D1 - Verfahren zur herstellung von tripeptiden - Google Patents

Verfahren zur herstellung von tripeptiden

Info

Publication number
DE60033553D1
DE60033553D1 DE60033553T DE60033553T DE60033553D1 DE 60033553 D1 DE60033553 D1 DE 60033553D1 DE 60033553 T DE60033553 T DE 60033553T DE 60033553 T DE60033553 T DE 60033553T DE 60033553 D1 DE60033553 D1 DE 60033553D1
Authority
DE
Germany
Prior art keywords
pro
sequence
ile
tripeptides
val
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60033553T
Other languages
English (en)
Other versions
DE60033553T2 (de
Inventor
Naoyuki Yamamoto
Keita Ueno
Masahiro Ejiri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Soft Drinks Co Ltd
Original Assignee
Calpis Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calpis Co Ltd filed Critical Calpis Co Ltd
Publication of DE60033553D1 publication Critical patent/DE60033553D1/de
Application granted granted Critical
Publication of DE60033553T2 publication Critical patent/DE60033553T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60033553T 1999-11-11 2000-11-10 Verfahren zur herstellung von tripeptiden Expired - Lifetime DE60033553T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP32108499 1999-11-11
JP32108499A JP4633876B2 (ja) 1999-11-11 1999-11-11 トリペプチドの製造方法
PCT/JP2000/007930 WO2001034828A1 (fr) 1999-11-11 2000-11-10 Procede d'obtention de tripeptides

Publications (2)

Publication Number Publication Date
DE60033553D1 true DE60033553D1 (de) 2007-04-05
DE60033553T2 DE60033553T2 (de) 2007-10-25

Family

ID=18128645

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60033553T Expired - Lifetime DE60033553T2 (de) 1999-11-11 2000-11-10 Verfahren zur herstellung von tripeptiden

Country Status (13)

Country Link
US (1) US6994987B1 (de)
EP (1) EP1231279B1 (de)
JP (1) JP4633876B2 (de)
CN (1) CN100523212C (de)
AT (1) ATE354668T1 (de)
AU (1) AU773587B2 (de)
CY (1) CY1106620T1 (de)
DE (1) DE60033553T2 (de)
DK (1) DK1231279T3 (de)
ES (1) ES2281361T3 (de)
NZ (1) NZ518957A (de)
PT (1) PT1231279E (de)
WO (1) WO2001034828A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10105041A1 (de) 2001-02-05 2002-08-14 Tell Pharm Ag Hergiswil Tripeptide und Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten
DE10105040A1 (de) * 2001-02-05 2002-08-14 Tell Pharm Ag Hergiswil Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems
DE10105038B4 (de) 2001-02-05 2005-07-07 Neurotell Ag Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems
ZA200507880B (en) * 2003-05-05 2006-12-27 Unilever Plc Hydrolysed casein product comprising tripeptides IPP and/or VPP
ES2277468B1 (es) * 2003-05-21 2008-07-01 Grupo Leche Pascual Peptidos bioactivos y derivados, procedimiento de produccion, cepas de enterococcus faecalis productoras de dichos peptidos bioactivos y sus aplicaciones.
UA87278C2 (ru) * 2003-08-01 2009-07-10 Калпис Ко., Лтд. Пептиды, которые биологически не разлагаются; ингибитор ангиотензинпревращающего фермента, лекарственное средство и функциональный пищевой продукт
RU2006125434A (ru) * 2003-12-15 2008-01-27 Юнилевер Н.В. (Nl) Пептиды, обладающие асе-ингибирующим действием
JP2008505653A (ja) * 2004-07-12 2008-02-28 ディーエスエム アイピー アセッツ ビー．ブイ． 血圧降下タンパク質加水分解物
CN101084004A (zh) * 2004-12-22 2007-12-05 帝斯曼知识产权资产管理有限公司 单个酶促步骤中的血压降低寡肽
AU2006212485B2 (en) * 2005-02-09 2010-03-11 Unilever Plc Food products comprising hydrolysed milk solids with improved taste
ES2599859T3 (es) * 2005-02-24 2017-02-03 Dsm Ip Assets B.V. Proceso enzimático para producir I-P-P a partir de caseína kappa
EP1726659B1 (de) * 2005-05-24 2009-12-30 Chr. Hansen A/S Isolierte Dipeptide mit ACE-Inhibitionseffekt
WO2007013426A1 (ja) 2005-07-26 2007-02-01 Calpis Co., Ltd. 発酵乳の製造方法及び発酵乳飲食品
EP2175273B1 (de) * 2005-11-09 2013-09-04 Ajinomoto Co., Inc. Kokumi-Verleihungsmittel
EP1992354B1 (de) * 2006-02-09 2014-04-09 Calpis Co., Ltd. Mittel zur prävention von rheumatoider arthritis zur oralen einnahme
KR101048663B1 (ko) * 2006-02-14 2011-07-12 칼피스가부시키가이샤 동맥경화 예방제, 혈관 내막의 비후 억제제 및 혈관 내피 기능 개선제
JP2011504363A (ja) * 2007-11-23 2011-02-10 ディーエスエム アイピー アセッツ ビー．ブイ． 改良された生理活性ペプチドの生成
CN102316886B (zh) * 2008-12-15 2014-06-18 可尔必思株式会社 抗皮肤老化肽
FI20095146A (fi) 2009-02-18 2010-08-19 Valio Oy Menetelmä elintarvikevalmisteen maun parantamiseksi
BR112012015984A2 (pt) * 2009-12-28 2018-05-29 Calpis Co., Ltd. composição para melhorar a função cerebral, e, polipeptídeo
JP2011136932A (ja) 2009-12-28 2011-07-14 Calpis Co Ltd 脳機能改善用組成物および脳機能を改善する方法
CN103108646B (zh) * 2010-09-16 2014-06-11 可尔必思株式会社 脑功能改善用组合物及改善脑功能的方法
JP5718741B2 (ja) 2011-06-24 2015-05-13 カルピス株式会社 脳機能改善用ペプチドの酵素的製造方法
US9523109B2 (en) * 2011-06-24 2016-12-20 Calpis Co., Ltd. Method for enzymatically preparing peptides for use in improvement of brain function
US20130156884A1 (en) * 2011-12-19 2013-06-20 Triarco Industries Protease enzymes for increased protein digestion rate and absorption and methods of using the same
WO2013133031A1 (ja) 2012-03-09 2013-09-12 森永乳業株式会社 ジペプチジルペプチダーゼ－iｖ阻害剤
CN103215332A (zh) * 2013-04-16 2013-07-24 陕西科技大学 一种分步酶解羊乳酪蛋白制备ace抑制肽的方法
CN107814844A (zh) * 2017-12-12 2018-03-20 浙江辉肽生命健康科技有限公司 一种生物活性多肽vvppfl及其制备方法和应用
CN111919963B (zh) * 2020-07-10 2021-06-01 青岛农业大学 一种从小麦面筋蛋白中酶法制备富含ipp和vpp水解物的方法
US20240158440A1 (en) * 2021-03-24 2024-05-16 Morinaga Milk Industry Co., Ltd. Peptide and composition containing peptide as active ingredient

Family Cites Families (36)

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US3846560A (en) 1971-07-22 1974-11-05 Quaker Oats Co Process of making a base for protein beverages
US3876806A (en) 1971-10-14 1975-04-08 Quaker Oats Co Process for the preparation of acid soluble polypeptides and carbonated beverages containing same
US4107334A (en) 1976-10-13 1978-08-15 Pfizer Inc. Modified protein
CH636248A5 (fr) 1979-03-09 1983-05-31 Nestle Sa Procede de preparation d'un hydrolysat de proteines purifie.
JPS6023086B2 (ja) * 1982-09-04 1985-06-05 工業技術院長 アンジオテンシン転換酵素阻害剤
JPS60262561A (ja) 1984-06-08 1985-12-25 House Food Ind Co Ltd 大豆蛋白質水溶液の処理方法
US4585757A (en) 1984-07-27 1986-04-29 Texas Tech University Health Sciences Center Hypotensive active peptides
US4687840A (en) 1986-02-11 1987-08-18 Texas Tech University Health Sciences Center Hypotensive active peptides
DD300815A5 (de) 1989-07-07 1992-08-06 Nestle Sa Proteinhydrolyse
NL9000422A (nl) 1990-02-21 1991-09-16 Nl Zuivelonderzoek Inst Werkwijze voor de bereiding van een gefermenteerd melkprodukt.
EP0445606B1 (de) 1990-02-27 1997-01-22 The Agency of Industrial Science and Technology Oligopeptide, sie enthaltende pharmazeutische und Futterzusammensetzung und Benützung von Oligopeptiden
DE69127020T2 (de) 1990-05-18 1998-01-29 Morinaga Milk Industry Co Ltd Milchproteinhydrolysate und Zusammensetzungen zur Verwendung als Haar- und Hautbehandlungsmittel
JP2571734B2 (ja) 1991-08-23 1997-01-16 株式会社ヤクルト本社 乳酸菌飲料
US5486461A (en) 1991-11-08 1996-01-23 Novo Nordisk A/S Casein hydrolyzate and method for production of such casein hydrolyzate
JPH05244947A (ja) * 1992-03-04 1993-09-24 Mercian Corp 新規ポストプロリンエンドペプチダーゼおよびその製造方法
JP3488722B2 (ja) * 1992-03-04 2004-01-19 カルピス株式会社 カルシウム吸収促進活性剤及びその製造法
FI94088C (fi) 1992-03-13 1995-07-25 Valio Oy Menetelmä fenyylialaniinin poistamiseksi proteiinipitoisista koostumuksista
US5418218A (en) 1992-07-10 1995-05-23 The University Of Maryland At Baltimore Histidyl-proline diketopiperazine (cyclo his-pro) a cns-active pharmacologic agent
JP3483604B2 (ja) * 1992-12-03 2004-01-06 昭和産業株式会社 アミノ酸の製造方法
JPH07115969A (ja) * 1993-10-25 1995-05-09 Asahi Chem Ind Co Ltd 加水分解蛋白質の製造方法
US5656268A (en) 1995-04-21 1997-08-12 Sorodsky; Michael Biological product
US5618689A (en) 1995-05-25 1997-04-08 Nestec S.A. Enhanced procedures for preparing food hydrolysates
ATE218036T1 (de) 1996-12-23 2002-06-15 Dsm Nv Verfahren zur herstellung eines proteinhydrolysates
JP4204653B2 (ja) 1997-06-20 2009-01-07 リンテック株式会社 シート剥離装置および方法
JPH1116461A (ja) 1997-06-26 1999-01-22 Matsushita Electric Works Ltd 感熱スイッチ
JP4727770B2 (ja) * 1997-09-26 2011-07-20 カルピス株式会社 尿中カテコールアミン低下、尿中ノルアドレナリン低下、尿中ドーパミン低下及びＦｉｓｃｈｅｒ比低下の少なくとも１つの軽減剤
JP3028411B2 (ja) * 1997-09-26 2000-04-04 カルピス株式会社 トリペプチド高生産性ラクトバチルス・ヘルベチカス乳酸菌
JP2873327B2 (ja) * 1998-01-23 1999-03-24 工業技術院長 アンジオテンシン変換酵素阻害剤
US6221423B1 (en) 1998-04-13 2001-04-24 Protein Technologies Int'l Inc. Short-chained peptide material
AU2001245537A1 (en) 2000-03-10 2001-09-24 Monsanto Company Anti-hypertensive peptides
WO2001068114A1 (en) 2000-03-10 2001-09-20 Monsanto Company Novel peptides with anti-hypertensive activity
NZ518375A (en) 2000-03-13 2003-07-25 Morinaga Milk Industry Co Ltd Protein hydrolyzates, process for producing the same and drinks and foods containing the protein hydrolyzates
US20030040475A1 (en) 2001-01-16 2003-02-27 Yasuhiro Toba Agents for improving lipid metabolism and reducing high blood pressure
US6815426B2 (en) 2001-02-16 2004-11-09 E. I. Du Pont De Nemours And Company Angiogenesis-inhibitory tripeptides, compositions and their methods of use
WO2002071854A1 (en) 2001-03-09 2002-09-19 Unilever N.V. Fermented milk product
US6589574B2 (en) 2001-03-19 2003-07-08 Council Of Scientific & Industrial Research Process for preparation of protein-hydrolysate from milk protein

Also Published As

Publication number Publication date
PT1231279E (pt) 2007-05-31
CY1106620T1 (el) 2012-01-25
AU1306001A (en) 2001-06-06
ATE354668T1 (de) 2007-03-15
CN100523212C (zh) 2009-08-05
JP4633876B2 (ja) 2011-02-16
CN1423704A (zh) 2003-06-11
WO2001034828A1 (fr) 2001-05-17
EP1231279A4 (de) 2004-07-21
EP1231279B1 (de) 2007-02-21
DK1231279T3 (da) 2007-04-10
DE60033553T2 (de) 2007-10-25
JP2001136995A (ja) 2001-05-22
AU773587B2 (en) 2004-05-27
US6994987B1 (en) 2006-02-07
NZ518957A (en) 2003-08-29
ES2281361T3 (es) 2007-10-01
EP1231279A1 (de) 2002-08-14

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