AR066614A1 - Compuesto de quinolina, su uso para preparar un medicamento y composicion farmaceutica que lo comprende - Google Patents

Compuesto de quinolina, su uso para preparar un medicamento y composicion farmaceutica que lo comprende

Info

Publication number
AR066614A1
AR066614A1 ARP080102096A ARP080102096A AR066614A1 AR 066614 A1 AR066614 A1 AR 066614A1 AR P080102096 A ARP080102096 A AR P080102096A AR P080102096 A ARP080102096 A AR P080102096A AR 066614 A1 AR066614 A1 AR 066614A1
Authority
AR
Argentina
Prior art keywords
substituted
heterocycloalkyl
heteroaryl
aryl
compound
Prior art date
Application number
ARP080102096A
Other languages
English (en)
Spanish (es)
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of AR066614A1 publication Critical patent/AR066614A1/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
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    • C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
    • C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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    • C—CHEMISTRY; METALLURGY
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D498/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • General Health & Medical Sciences (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
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  • Epidemiology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Urology & Nephrology (AREA)
  • Hematology (AREA)
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  • Transplantation (AREA)
  • Psychology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pain & Pain Management (AREA)
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ARP080102096A 2007-05-18 2008-05-16 Compuesto de quinolina, su uso para preparar un medicamento y composicion farmaceutica que lo comprende AR066614A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93876107P 2007-05-18 2007-05-18

Publications (1)

Publication Number Publication Date
AR066614A1 true AR066614A1 (es) 2009-09-02

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ARP080102096A AR066614A1 (es) 2007-05-18 2008-05-16 Compuesto de quinolina, su uso para preparar un medicamento y composicion farmaceutica que lo comprende

Country Status (31)

Country Link
US (6) US20100168100A1 (enExample)
EP (3) EP2596793B1 (enExample)
JP (3) JP4814396B2 (enExample)
KR (1) KR101458660B1 (enExample)
CN (1) CN101754759B (enExample)
AR (1) AR066614A1 (enExample)
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CA2686016A1 (en) 2008-11-27
JO2891B1 (en) 2015-09-15
EP2162131A1 (en) 2010-03-17
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KR101458660B1 (ko) 2014-11-06
JP4814396B2 (ja) 2011-11-16
WO2008144464A1 (en) 2008-11-27
US8404837B2 (en) 2013-03-26
ES2547256T3 (es) 2015-10-02
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AU2008254915B2 (en) 2012-02-09
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US8785433B2 (en) 2014-07-22
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US20140296224A1 (en) 2014-10-02
KR20100017852A (ko) 2010-02-16
US20080300239A1 (en) 2008-12-04
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DK2162131T3 (da) 2013-05-27
TW200911784A (en) 2009-03-16
PT2162131E (pt) 2013-04-23
AU2008254915A1 (en) 2008-11-27
ZA200907777B (en) 2010-07-28
US20120165321A1 (en) 2012-06-28
SI2162131T1 (sl) 2013-07-31
MX342959B (es) 2016-10-18
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