MY164523A
(en)
*
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
EP1736478B1
(en)
*
|
2000-05-26 |
2015-07-22 |
IDENIX Pharmaceuticals, Inc. |
Methods and compositions for treating flaviviruses and pestiviruses
|
JP2005504087A
(ja)
*
|
2001-09-28 |
2005-02-10 |
イデニクス(ケイマン)リミテツド |
4’が修飾されたヌクレオシドを使用するc型肝炎ウイルス治療のための方法および組成物
|
US8101209B2
(en)
*
|
2001-10-09 |
2012-01-24 |
Flamel Technologies |
Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
|
FR2830447B1
(fr)
*
|
2001-10-09 |
2004-04-16 |
Flamel Tech Sa |
Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques
|
ATE407674T1
(de)
*
|
2002-04-09 |
2008-09-15 |
Flamel Tech Sa |
Orale pharmazeutische formulierung in form einer wässrigen suspension von mikrokapseln zur modifizierten freisetzung von amoxicillin
|
CN100553625C
(zh)
|
2002-04-09 |
2009-10-28 |
弗拉梅技术公司 |
活性成分微囊的口服混悬液
|
US7608600B2
(en)
*
|
2002-06-28 |
2009-10-27 |
Idenix Pharmaceuticals, Inc. |
Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
|
CN101172993A
(zh)
*
|
2002-06-28 |
2008-05-07 |
埃迪尼克斯(开曼)有限公司 |
用于治疗黄病毒感染的2′-c-甲基-3′-o-l-缬氨酸酯核糖呋喃基胞苷
|
MXPA04012802A
(es)
*
|
2002-06-28 |
2005-04-19 |
Idenix Cayman Ltd |
Ester 2'-c-metil-3'-o-l-valina de ribofuranosil-citidina para el tratamiento de infecciones por flaviviridae.
|
MXPA05005192A
(es)
*
|
2002-11-15 |
2005-09-08 |
Idenix Cayman Ltd |
Nucleosidos ramificados en la posicion 2' y mutacion de flaviviridae.
|
CA2509687C
(en)
*
|
2002-12-12 |
2012-08-14 |
Idenix (Cayman) Limited |
Process for the production of 2'-branched nucleosides
|
CA2511616A1
(en)
*
|
2002-12-23 |
2004-07-15 |
Idenix (Cayman) Limited |
Process for the production of 3'-nucleoside prodrugs
|
DE602004003389T2
(de)
*
|
2003-06-19 |
2007-09-13 |
F. Hoffmann-La Roche Ag |
Verfahren zur herstellung von 4'-azidonukleosidderivaten
|
WO2006000922A2
(en)
*
|
2004-06-23 |
2006-01-05 |
Idenix (Cayman) Limited |
5-aza-7-deazapurine derivatives for treating infections with flaviviridae
|
EP1794172B1
(en)
*
|
2004-08-23 |
2009-07-15 |
F.Hoffmann-La Roche Ag |
Antiviral 4'-azido-nucleosides
|
JP4516863B2
(ja)
*
|
2005-03-11 |
2010-08-04 |
株式会社ケンウッド |
音声合成装置、音声合成方法及びプログラム
|
US20070166378A1
(en)
*
|
2005-06-09 |
2007-07-19 |
Flamel Technologies, Inc. |
Oral ribavirin pharmaceutical compositions
|
JP2009504704A
(ja)
*
|
2005-08-15 |
2009-02-05 |
エフ.ホフマン−ラ ロシュ アーゲー |
抗ウイルス4′−置換プロヌクレオチドホスホルアミダート
|
BRPI0616385A2
(pt)
*
|
2005-09-22 |
2011-06-21 |
Hoffmann La Roche |
o-acilação seletiva de nucleosìdeos
|
RU2422454C2
(ru)
*
|
2005-12-09 |
2011-06-27 |
Ф. Хоффманн-Ля Рош Аг |
Антивирусные нуклеозиды
|
ES2350497T3
(es)
*
|
2005-12-14 |
2011-01-24 |
F. Hoffmann-La Roche Ag |
Formulación de profármacos para el vhc.
|
ATE482690T1
(de)
*
|
2005-12-14 |
2010-10-15 |
Hoffmann La Roche |
Hcv-prodrug-formulierung
|
ES2422290T3
(es)
*
|
2005-12-23 |
2013-09-10 |
Idenix Pharmaceuticals Inc |
Procedimiento para preparar un producto intermedio sintético para la preparación de nucleósidos ramificados
|
WO2007113159A1
(en)
|
2006-04-04 |
2007-10-11 |
F. Hoffmann-La Roche Ag |
3',5'-di-o-acylated nucleosides for hcv treatment
|
BRPI0719174A2
(pt)
*
|
2006-10-10 |
2017-06-13 |
Hoffmann La Roche |
preparação de pirimidinas ribofuranosil nucleosídeos
|
AU2007306405A1
(en)
|
2006-10-10 |
2008-04-17 |
Medivir Ab |
HCV nucleoside inhibitor
|
US8501933B2
(en)
|
2006-11-09 |
2013-08-06 |
Roche Palo Alto Llc |
Thiazole and oxazole-substituted arylamides as P2X3 and P2X2/3 antagonists
|
CN101528717B
(zh)
|
2006-11-09 |
2013-04-24 |
弗·哈夫曼-拉罗切有限公司 |
噻唑和*唑-取代的芳基酰胺类化合物
|
ATE478084T1
(de)
*
|
2006-12-11 |
2010-09-15 |
Hoffmann La Roche |
Verfahren zur herstellung von 4'- azidocytidinderivaten
|
US20080261913A1
(en)
|
2006-12-28 |
2008-10-23 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of liver disorders
|
BRPI0808089A2
(pt)
|
2007-02-28 |
2014-07-15 |
Conatus Pharmaceuticals Inc |
Método para tratar uma doença do fígado, para diminuir um nível elevado de uma enzima do fígado, para inibir uma cascata de sinalização de tnf-alfa e uma cascata de sinalização de alfa-faz, para reduzir um dano ao fígado, para suprimir a apoptose excessiva em uma célula de fígado, e para inibir a replicação do vírus da hepatite c.
|
WO2008106167A1
(en)
*
|
2007-02-28 |
2008-09-04 |
Conatus Pharmaceuticals, Inc. |
Combination therapy comprising matrix metalloproteinase inhibitors and caspase inhibitors for the treatment of liver diseases
|
EP2142178B1
(en)
*
|
2007-03-29 |
2012-01-11 |
F. Hoffmann-La Roche AG |
Pharmaceutical composition and process
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
CL2008003511A1
(es)
*
|
2007-11-29 |
2010-02-19 |
Metabasis Therapeutics Inc |
Compuestos derivados nucleotidicos, inhibidores de polimerasa ns5b del virus de la hepatitis c; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la hepatitis c.
|
AU2008337660B2
(en)
*
|
2007-12-17 |
2014-02-06 |
F. Hoffmann-La Roche Ag |
Triazole-substituted arylamide derivatives and their use as P2X3 and /or P2X2/3 purinergic receptor antagonists
|
JP5301561B2
(ja)
*
|
2007-12-17 |
2013-09-25 |
エフ.ホフマン−ラ ロシュ アーゲー |
新規なピラゾール置換アリールアミド
|
WO2009077365A1
(en)
|
2007-12-17 |
2009-06-25 |
F. Hoffmann-La Roche Ag |
Novel imidazole-substituted arylamides
|
EP2570407B1
(en)
*
|
2007-12-17 |
2014-08-13 |
F. Hoffmann-La Roche AG |
Tetrazole-substituted arylamide derivatives and their use as p2x3 and/or p2x2/3 purinergic receptor antagonists
|
US8173621B2
(en)
*
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
JP2011526893A
(ja)
*
|
2008-07-02 |
2011-10-20 |
イデニク プハルマセウティカルス,インコーポレイテッド |
ウイルス感染の治療のための化合物、及び医薬組成物
|
EP2315802A4
(en)
*
|
2008-07-31 |
2012-04-18 |
3M Innovative Properties Co |
AZIUM COMPOSITIONS AND METHOD FOR THEIR PREPARATION AND USE
|
CA2745284A1
(en)
*
|
2008-12-18 |
2010-06-24 |
F. Hoffmann-La Roche Ag |
Biomarkers for hcv treatment response
|
TW201031675A
(en)
*
|
2008-12-23 |
2010-09-01 |
Pharmasset Inc |
Synthesis of purine nucleosides
|
EP2389164B1
(en)
*
|
2009-01-21 |
2014-08-13 |
F. Hoffmann-La Roche AG |
Pharmaceutical compositions comprising a hcv polymerase inhibitor prodrug
|
WO2010101967A2
(en)
|
2009-03-04 |
2010-09-10 |
Idenix Pharmaceuticals, Inc. |
Phosphothiophene and phosphothiazole hcv polymerase inhibitors
|
JP2012519661A
(ja)
|
2009-03-06 |
2012-08-30 |
エフ.ホフマン−ラ ロシュ アーゲー |
抗ウイルス性複素環化合物
|
US8618076B2
(en)
|
2009-05-20 |
2013-12-31 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
TWI576352B
(zh)
|
2009-05-20 |
2017-04-01 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
SG177301A1
(en)
*
|
2009-06-22 |
2012-02-28 |
Hoffmann La Roche |
Novel indole, indazole and benzimidazole arylamides as p2x3 and/or p2x2/3 antagonists
|
ES2593405T3
(es)
*
|
2009-06-22 |
2016-12-09 |
F. Hoffmann-La Roche Ag |
Nuevas arilamidas sustituidas por benzoxazolona
|
CN102574778B
(zh)
*
|
2009-06-22 |
2015-01-07 |
弗·哈夫曼-拉罗切有限公司 |
新的联苯基和苯基-吡啶酰胺类化合物
|
BRPI1011744A2
(pt)
|
2009-06-24 |
2016-03-22 |
Hoffmann La Roche |
composto antiviral heterocíclico.
|
JP2013501068A
(ja)
|
2009-08-05 |
2013-01-10 |
アイディニックス ファーマシューティカルズ インコーポレイテッド |
大環状セリンプロテアーゼ阻害剤
|
CN102498100A
(zh)
|
2009-09-21 |
2012-06-13 |
弗·哈夫曼-拉罗切有限公司 |
抗病毒杂环化合物
|
WO2011063076A1
(en)
|
2009-11-19 |
2011-05-26 |
Itherx Pharmaceuticals, Inc. |
Methods of treating hepatitis c virus with oxoacetamide compounds
|
CA2778206A1
(en)
|
2009-11-21 |
2011-05-26 |
F. Hoffmann-La Roche Ag |
Heterocyclic antiviral compounds
|
NZ600608A
(en)
|
2009-12-18 |
2015-01-30 |
Idenix Pharmaceuticals Inc |
5,5-fused arylene or heteroarylene hepatitis c virus inhibitors
|
PL2528930T3
(pl)
*
|
2010-01-28 |
2014-03-31 |
Riboscience Llc |
4`-azydonukleozydy jako związki przeciw hcv
|
HUE026235T2
(en)
|
2010-03-31 |
2016-06-28 |
Gilead Pharmasset Llc |
Crystalline (S) -isopropyl 2 - (((S) - (((2R, 3R, 4R, 5R) -5- (2,4-dioxo-3,4-dihydropyrimidin-1 (2H) -IL) - 4-Fluoro-3-hydroxy-4-methyltetrahydrofuran-2-IL) methoxy) (phenoxy) phosphoryl) amino) propanoate
|
US8563530B2
(en)
|
2010-03-31 |
2013-10-22 |
Gilead Pharmassel LLC |
Purine nucleoside phosphoramidate
|
CN102917585A
(zh)
|
2010-04-01 |
2013-02-06 |
埃迪尼克斯医药公司 |
用于治疗病毒感染的化合物和药物组合物
|
US8877731B2
(en)
|
2010-09-22 |
2014-11-04 |
Alios Biopharma, Inc. |
Azido nucleosides and nucleotide analogs
|
TW201242974A
(en)
|
2010-11-30 |
2012-11-01 |
Gilead Pharmasset Llc |
Compounds
|
WO2012080050A1
(en)
|
2010-12-14 |
2012-06-21 |
F. Hoffmann-La Roche Ag |
Solid forms of a phenoxybenzenesulfonyl compound
|
AR085352A1
(es)
|
2011-02-10 |
2013-09-25 |
Idenix Pharmaceuticals Inc |
Inhibidores macrociclicos de serina proteasa, sus composiciones farmaceuticas y su uso para tratar infecciones por hcv
|
US20120252721A1
(en)
|
2011-03-31 |
2012-10-04 |
Idenix Pharmaceuticals, Inc. |
Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
|
WO2012154321A1
(en)
|
2011-03-31 |
2012-11-15 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
US9403863B2
(en)
|
2011-09-12 |
2016-08-02 |
Idenix Pharmaceuticals Llc |
Substituted carbonyloxymethylphosphoramidate compounds and pharmaceutical compositions for the treatment of viral infections
|
EP2755985B1
(en)
|
2011-09-12 |
2017-11-01 |
Idenix Pharmaceuticals LLC |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
PL2709613T5
(pl)
|
2011-09-16 |
2020-12-14 |
Gilead Pharmasset Llc |
Metody leczenia hcv
|
US8507460B2
(en)
|
2011-10-14 |
2013-08-13 |
Idenix Pharmaceuticals, Inc. |
Substituted 3′,5′-cyclic phosphates of purine nucleotide compounds and pharmaceutical compositions for the treatment of viral infections
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
CN104185420B
(zh)
|
2011-11-30 |
2017-06-09 |
埃默里大学 |
用于治疗或预防逆转录病毒和其它病毒感染的抗病毒jak抑制剂
|
WO2013133927A1
(en)
|
2012-02-13 |
2013-09-12 |
Idenix Pharmaceuticals, Inc. |
Pharmaceutical compositions of 2'-c-methyl-guanosine, 5'-[2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)thio]ethyl n-(phenylmethyl)phosphoramidate]
|
US9109001B2
(en)
|
2012-05-22 |
2015-08-18 |
Idenix Pharmaceuticals, Inc. |
3′,5′-cyclic phosphoramidate prodrugs for HCV infection
|
US9296778B2
(en)
|
2012-05-22 |
2016-03-29 |
Idenix Pharmaceuticals, Inc. |
3′,5′-cyclic phosphate prodrugs for HCV infection
|
JP6165848B2
(ja)
|
2012-05-22 |
2017-07-19 |
イデニク ファーマシューティカルズ エルエルシー |
肝疾患のためのd−アミノ酸化合物
|
CA2871547C
(en)
|
2012-05-25 |
2021-05-25 |
Janssen R&D Ireland |
Uracyl spirooxetane nucleosides
|
WO2014052638A1
(en)
|
2012-09-27 |
2014-04-03 |
Idenix Pharmaceuticals, Inc. |
Esters and malonates of sate prodrugs
|
AU2013329521B2
(en)
|
2012-10-08 |
2018-04-19 |
Centre National De La Recherche Scientifique |
2'-chloro nucleoside analogs for HCV infection
|
WO2014063019A1
(en)
|
2012-10-19 |
2014-04-24 |
Idenix Pharmaceuticals, Inc. |
Dinucleotide compounds for hcv infection
|
EP2909222B1
(en)
|
2012-10-22 |
2021-05-26 |
Idenix Pharmaceuticals LLC |
2',4'-bridged nucleosides for hcv infection
|
EP2920195A1
(en)
|
2012-11-14 |
2015-09-23 |
IDENIX Pharmaceuticals, Inc. |
D-alanine ester of rp-nucleoside analog
|
WO2014078436A1
(en)
|
2012-11-14 |
2014-05-22 |
Idenix Pharmaceuticals, Inc. |
D-alanine ester of sp-nucleoside analog
|
WO2014099941A1
(en)
|
2012-12-19 |
2014-06-26 |
Idenix Pharmaceuticals, Inc. |
4'-fluoro nucleosides for the treatment of hcv
|
SG10201706949VA
(en)
|
2013-01-31 |
2017-09-28 |
Gilead Pharmasset Llc |
Combination formulation of two antiviral compounds
|
WO2014137926A1
(en)
|
2013-03-04 |
2014-09-12 |
Idenix Pharmaceuticals, Inc. |
3'-deoxy nucleosides for the treatment of hcv
|
US9339541B2
(en)
|
2013-03-04 |
2016-05-17 |
Merck Sharp & Dohme Corp. |
Thiophosphate nucleosides for the treatment of HCV
|
US20140271547A1
(en)
|
2013-03-13 |
2014-09-18 |
Idenix Pharmaceuticals, Inc. |
Amino acid phosphoramidate pronucleotides of 2'-cyano, azido and amino nucleosides for the treatment of hcv
|
US9187515B2
(en)
|
2013-04-01 |
2015-11-17 |
Idenix Pharmaceuticals Llc |
2′,4′-fluoro nucleosides for the treatment of HCV
|
WO2014197578A1
(en)
|
2013-06-05 |
2014-12-11 |
Idenix Pharmaceuticals, Inc. |
1',4'-thio nucleosides for the treatment of hcv
|
CA2913206C
(en)
|
2013-06-26 |
2022-08-02 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
EP3027636B1
(en)
|
2013-08-01 |
2022-01-05 |
Idenix Pharmaceuticals LLC |
D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
|
MX2016002185A
(es)
|
2013-08-27 |
2016-06-06 |
Gilead Pharmasset Llc |
Formulacion combinada de dos compuestos antivirales.
|
US20160229866A1
(en)
|
2013-09-20 |
2016-08-11 |
Idenix Pharmaceuticals Inc. |
Hepatitis c virus inhibitors
|
WO2015061683A1
(en)
|
2013-10-25 |
2015-04-30 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate and d-alanine thiophosphoramidate pronucleotides of nucleoside compounds useful for the treatment of hcv
|
WO2015066370A1
(en)
|
2013-11-01 |
2015-05-07 |
Idenix Pharmaceuticals, Inc. |
D-alanine phosphoramidate pronucleotides of 2'-methyl 2'-fluoro guanosine nucleoside compounds for the treatment of hcv
|
US20170198005A1
(en)
|
2013-11-27 |
2017-07-13 |
Idenix Pharmaceuticals Llc |
2'-dichloro and 2'-fluoro-2'-chloro nucleoside analogues for hcv infection
|
US10683321B2
(en)
|
2013-12-18 |
2020-06-16 |
Idenix Pharmaceuticals Llc |
4′-or nucleosides for the treatment of HCV
|
CN114404427A
(zh)
|
2014-02-13 |
2022-04-29 |
配体药物公司 |
前药化合物及其用途
|
WO2015134560A1
(en)
|
2014-03-05 |
2015-09-11 |
Idenix Pharmaceuticals, Inc. |
Solid forms of a flaviviridae virus inhibitor compound and salts thereof
|
US20170135990A1
(en)
|
2014-03-05 |
2017-05-18 |
Idenix Pharmaceuticals Llc |
Pharmaceutical compositions comprising a 5,5-fused heteroarylene flaviviridae inhibitor and their use for treating or preventing flaviviridae infection
|
WO2015161137A1
(en)
|
2014-04-16 |
2015-10-22 |
Idenix Pharmaceuticals, Inc. |
3'-substituted methyl or alkynyl nucleosides for the treatment of hcv
|
US9994600B2
(en)
|
2014-07-02 |
2018-06-12 |
Ligand Pharmaceuticals, Inc. |
Prodrug compounds and uses therof
|
SG11201702430WA
(en)
|
2014-09-26 |
2017-04-27 |
Riboscience Llc |
4'-vinyl substituted nucleoside derivatives as inhibitors of respiratory syncytial virus rna replication
|
KR20230130175A
(ko)
|
2014-12-26 |
2023-09-11 |
에모리 유니버시티 |
N4-하이드록시시티딘, 이와 관련된 유도체 및 이의 항 바이러스적 용도
|
US10675296B2
(en)
|
2017-07-11 |
2020-06-09 |
Gilead Sciences, Inc. |
Compositions comprising an RNA polymerase inhibitor and cyclodextrin for treating viral infections
|
AU2018378832B9
(en)
|
2017-12-07 |
2021-05-27 |
Emory University |
N4-hydroxycytidine and derivatives and anti-viral uses related thereto
|
EP3737676B1
(en)
|
2018-01-09 |
2024-03-06 |
Ligand Pharmaceuticals, Inc. |
Acetal compounds and therapeutic uses thereof
|
US11660307B2
(en)
|
2020-01-27 |
2023-05-30 |
Gilead Sciences, Inc. |
Methods for treating SARS CoV-2 infections
|
WO2021207049A1
(en)
|
2020-04-06 |
2021-10-14 |
Gilead Sciences, Inc. |
Inhalation formulations of 1'-cyano substituted carbanucleoside analogs
|
EP4157272A1
(en)
|
2020-05-29 |
2023-04-05 |
Gilead Sciences, Inc. |
Remdesivir treatment methods
|
MX2022016405A
(es)
|
2020-06-24 |
2023-01-30 |
Gilead Sciences Inc |
Análogos de nucleósido de 1¿-ciano y usos de estos.
|
WO2022008025A1
(en)
*
|
2020-07-05 |
2022-01-13 |
Since & Technology Development Fund Authority |
2-hydroxyiminopyrimidine nucleosides and derivitives and antiviral uses thereto
|
JP2023540225A
(ja)
|
2020-08-27 |
2023-09-22 |
ギリアード サイエンシーズ, インコーポレイテッド |
ウイルス感染症の治療のための化合物及び方法
|
TW202400185A
(zh)
|
2022-03-02 |
2024-01-01 |
美商基利科學股份有限公司 |
用於治療病毒感染的化合物及方法
|