AP418A - A process for preparing useful intermediates in the synthesis of substituted imidazole compounds. - Google Patents

A process for preparing useful intermediates in the synthesis of substituted imidazole compounds. Download PDF

Info

Publication number
AP418A
AP418A APAP/P/1993/000565A AP9300565A AP418A AP 418 A AP418 A AP 418A AP 9300565 A AP9300565 A AP 9300565A AP 418 A AP418 A AP 418A
Authority
AP
ARIPO
Prior art keywords
compound
phenyl
cgalkyl
substituted
unsubstituted
Prior art date
Application number
APAP/P/1993/000565A
Other languages
English (en)
Other versions
AP9300565A0 (en
Inventor
Mohamed Kheir Mokhallalati
Lendon Norwood Pridgen
Susan Shilcrat
Joseph Weinstock
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of AP9300565A0 publication Critical patent/AP9300565A0/xx
Application granted granted Critical
Publication of AP418A publication Critical patent/AP418A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
APAP/P/1993/000565A 1992-09-23 1993-09-17 A process for preparing useful intermediates in the synthesis of substituted imidazole compounds. AP418A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929220068A GB9220068D0 (en) 1992-09-23 1992-09-23 Process

Publications (2)

Publication Number Publication Date
AP9300565A0 AP9300565A0 (en) 1993-10-31
AP418A true AP418A (en) 1995-10-24

Family

ID=10722348

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1993/000565A AP418A (en) 1992-09-23 1993-09-17 A process for preparing useful intermediates in the synthesis of substituted imidazole compounds.

Country Status (37)

Country Link
EP (1) EP0662961B1 (ko)
JP (1) JPH08501307A (ko)
KR (1) KR100297505B1 (ko)
CN (1) CN1035613C (ko)
AP (1) AP418A (ko)
AT (1) ATE186531T1 (ko)
AU (1) AU676848B2 (ko)
BG (1) BG62328B1 (ko)
BR (1) BR9307201A (ko)
CA (1) CA2145181C (ko)
CZ (1) CZ282281B6 (ko)
DE (1) DE69327007T2 (ko)
DK (1) DK0662961T3 (ko)
ES (1) ES2137999T3 (ko)
FI (1) FI113170B (ko)
GB (1) GB9220068D0 (ko)
GR (1) GR3032015T3 (ko)
HK (1) HK1012357A1 (ko)
HU (1) HU224071B1 (ko)
IL (1) IL107047A (ko)
MA (1) MA22980A1 (ko)
MX (1) MX9305844A (ko)
MY (1) MY110202A (ko)
NO (1) NO304688B1 (ko)
NZ (1) NZ256223A (ko)
OA (1) OA10138A (ko)
PH (1) PH31154A (ko)
PL (1) PL173450B1 (ko)
RO (1) RO113146B1 (ko)
RU (1) RU2128174C1 (ko)
SA (1) SA93140423B1 (ko)
SI (1) SI9300494A (ko)
SK (1) SK281227B6 (ko)
TW (1) TW409124B (ko)
UA (1) UA41903C2 (ko)
WO (1) WO1994006776A1 (ko)
ZA (1) ZA936962B (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9220068D0 (en) * 1992-09-23 1992-11-04 Smithkline Beecham Corp Process
US5565577A (en) * 1992-09-23 1996-10-15 Smithkline Beecham Corporation Process for preparing 1-alkyaryl-2-alkyl-5-formylimidazole
JP5245408B2 (ja) 2005-08-23 2013-07-24 宇部興産株式会社 １−置換−５−アシルイミダゾール化合物の製法
KR101472686B1 (ko) * 2013-07-09 2014-12-16 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 제조방법
CN103435617B (zh) * 2013-08-22 2016-04-27 南京华安药业有限公司 一种6,7-二氢-5H-吡咯并[1,2-a]咪唑-2-甲醛的合成方法
CN115894192A (zh) * 2022-12-05 2023-04-04 苏州诚和医药化学有限公司 一种2-溴丙二醛的合成方法、应用及2-溴丙二醛

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4482723A (en) * 1983-04-11 1984-11-13 Pfizer Inc. Process for preparation of 4-acetyl-2-substituted-imidazoles
WO1994006776A1 (en) * 1992-09-23 1994-03-31 Smithkline Beecham Corporation Process of synthesizing useful intermediates of substituted imidazole compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5671073A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd Imidazole derivative
US4602093A (en) * 1984-02-08 1986-07-22 Merck & Co., Inc. Novel substituted imidazoles, their preparation and use
DE3811621A1 (de) * 1988-04-07 1989-10-26 Merck Patent Gmbh Verfahren zur herstellung von 1h-imidazol-5-carbon-saeureestern oder -nitrilen und von pyrrol-3,4-carbonsaeureestern oder -nitrilen sowie verwendung der hergestellten verbindungen zur synthese von pilocarpin
US5234917A (en) * 1989-12-29 1993-08-10 Finkelstein Joseph A Substituted 5-(alkyl)carboxamide imidazoles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4482723A (en) * 1983-04-11 1984-11-13 Pfizer Inc. Process for preparation of 4-acetyl-2-substituted-imidazoles
WO1994006776A1 (en) * 1992-09-23 1994-03-31 Smithkline Beecham Corporation Process of synthesizing useful intermediates of substituted imidazole compounds

Also Published As

Publication number Publication date
MY110202A (en) 1998-02-28
SK37395A3 (en) 1995-08-09
AU676848B2 (en) 1997-03-27
CN1035613C (zh) 1997-08-13
SI9300494A (en) 1994-03-31
HU224071B1 (hu) 2005-05-30
CZ282281B6 (cs) 1997-06-11
RU95108600A (ru) 1997-01-10
IL107047A (en) 1998-04-05
DE69327007D1 (de) 1999-12-16
RU2128174C1 (ru) 1999-03-27
EP0662961A4 (en) 1996-07-31
PL173450B1 (pl) 1998-03-31
HUT71335A (en) 1995-11-28
EP0662961B1 (en) 1999-11-10
BG62328B1 (bg) 1999-08-31
NO951094L (no) 1995-03-22
SK281227B6 (sk) 2001-01-18
DE69327007T2 (de) 2000-04-20
PH31154A (en) 1998-03-20
GR3032015T3 (en) 2000-03-31
HU9500837D0 (en) 1995-05-29
CN1092411A (zh) 1994-09-21
AP9300565A0 (en) 1993-10-31
JPH08501307A (ja) 1996-02-13
NO304688B1 (no) 1999-02-01
FI951350A (fi) 1995-03-22
ATE186531T1 (de) 1999-11-15
MA22980A1 (fr) 1994-04-01
PL308173A1 (en) 1995-07-24
DK0662961T3 (da) 2000-04-17
UA41903C2 (uk) 2001-10-15
TW409124B (en) 2000-10-21
NO951094D0 (no) 1995-03-22
MX9305844A (es) 1994-03-31
OA10138A (en) 1996-12-18
FI951350A0 (fi) 1995-03-22
RO113146B1 (ro) 1998-04-30
KR100297505B1 (ko) 2001-10-24
IL107047A0 (en) 1993-12-28
GB9220068D0 (en) 1992-11-04
HK1012357A1 (en) 1999-07-30
CZ70895A3 (en) 1995-11-15
FI113170B (fi) 2004-03-15
EP0662961A1 (en) 1995-07-19
ES2137999T3 (es) 2000-01-01
ZA936962B (en) 1994-08-01
KR950703536A (ko) 1995-09-20
SA93140423B1 (ar) 2005-10-01
CA2145181C (en) 2004-11-16
NZ256223A (en) 1996-06-25
CA2145181A1 (en) 1994-03-31
BR9307201A (pt) 1999-03-30
BG99520A (bg) 1996-01-31
WO1994006776A1 (en) 1994-03-31
AU4849693A (en) 1994-04-12

Similar Documents

Publication Publication Date Title
US8350046B2 (en) Method for manufacturing aryl carboxamides
US7795471B2 (en) Process for trans-4-amino-1-cyclohexanecarboxylic acid derivatives
JP6688278B2 (ja) ４−アルコキシ−３−ヒドロキシピコリン酸の製造方法
JP2530848B2 (ja) Ｏ−置換ヒドロキシルアミンの製造法
RU2176241C2 (ru) Способ получения производных 3-амино-2-меркаптобензойной кислоты (варианты), производные бензотиазола и способ их получения
AP418A (en) A process for preparing useful intermediates in the synthesis of substituted imidazole compounds.
US6372933B1 (en) Process for preparing certain phenyl urea compounds
US5565577A (en) Process for preparing 1-alkyaryl-2-alkyl-5-formylimidazole
AU737994B2 (en) Process for preparing o-(3-amino-2-hydroxy-propyl)-hydroxymic acid halides
RU2154060C2 (ru) Способ получения 5-замещенного 2-хлорпиридина
PL190946B1 (pl) Związki 2-tiotiazolidyn-5-onu, sposoby ich wytwarzania oraz sposoby wytwarzania związków 2-imidazolidyn-5-onu
KR20040039430A (ko) (2-니트로페닐)아세토니트릴 유도체의 제조방법 및 그합성중간체
USRE40795E1 (en) Process for producing 5-substituted oxazole compounds and 5-substituted imidazole compounds
WO1997014688A1 (en) A PROCESS FOR THE PREPARATION OF α-CHLOROMETHYLPHENYLACETIC ACID DERIVATIVES
SU169457A1 (ru) Способ получения 2-алкил-6-замещенных-з-
RU2270195C1 (ru) Способ получения 5-амино-3-[n-ацил-n-алкиламино]-1-фенил-1,2,4-триазолов и 5-амино-3-[n-сульфонил-n-алкиламино]-1-фенил-1,2,4-триазолов
JPH1135563A (ja) アゾール−１−イルアルキルニトリル類の製造法
JPS63165354A (ja) 不斉シアンヒドリンの製造法
JP2007509092A (ja) α−（３−アリールチオ）−アセトフェノン類の製造方法
MXPA99009046A (en) Process for preparing o-(3-amino-2-hydroxy-propyl)-hydroxymic acid halides
JPH07278104A (ja) ５−アセトキシメチルピロール−２−カルボン酸誘導体の製造方法