RU95108600A - Способ получения промежуточных соединений замещенных производных имидазола - Google Patents

Способ получения промежуточных соединений замещенных производных имидазола

Info

Publication number
RU95108600A
RU95108600A RU95108600/04A RU95108600A RU95108600A RU 95108600 A RU95108600 A RU 95108600A RU 95108600/04 A RU95108600/04 A RU 95108600/04A RU 95108600 A RU95108600 A RU 95108600A RU 95108600 A RU95108600 A RU 95108600A
Authority
RU
Russia
Prior art keywords
production
imidazole
substituted derivatives
intermediate compounds
alkylaryl
Prior art date
Application number
RU95108600/04A
Other languages
English (en)
Other versions
RU2128174C1 (ru
Inventor
Кейр Мокаллалати Мохамед
Sy]
Норвуд Приджен Лендон
Шилкрэт Сюзн
Us]
Вейнсток Джозеф
Original Assignee
Смитклайн Бичам Корпорейшн (US)
Смитклайн Бичам Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Смитклайн Бичам Корпорейшн (US), Смитклайн Бичам Корпорейшн filed Critical Смитклайн Бичам Корпорейшн (US)
Publication of RU95108600A publication Critical patent/RU95108600A/ru
Application granted granted Critical
Publication of RU2128174C1 publication Critical patent/RU2128174C1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Изобретение относится к способу получения 1-алкиларил-2-алкил-5-формилимидазолов.

Claims (1)

  1. Изобретение относится к способу получения 1-алкиларил-2-алкил-5-формилимидазолов.
RU95108600A 1992-09-23 1993-09-07 Способ получения замещенных производных имидазола или их фармацевтически приемлемых солей RU2128174C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9220068.2 1992-09-23
GB929220068A GB9220068D0 (en) 1992-09-23 1992-09-23 Process

Publications (2)

Publication Number Publication Date
RU95108600A true RU95108600A (ru) 1997-01-10
RU2128174C1 RU2128174C1 (ru) 1999-03-27

Family

ID=10722348

Family Applications (1)

Application Number Title Priority Date Filing Date
RU95108600A RU2128174C1 (ru) 1992-09-23 1993-09-07 Способ получения замещенных производных имидазола или их фармацевтически приемлемых солей

Country Status (37)

Country Link
EP (1) EP0662961B1 (ru)
JP (1) JPH08501307A (ru)
KR (1) KR100297505B1 (ru)
CN (1) CN1035613C (ru)
AP (1) AP418A (ru)
AT (1) ATE186531T1 (ru)
AU (1) AU676848B2 (ru)
BG (1) BG62328B1 (ru)
BR (1) BR9307201A (ru)
CA (1) CA2145181C (ru)
CZ (1) CZ282281B6 (ru)
DE (1) DE69327007T2 (ru)
DK (1) DK0662961T3 (ru)
ES (1) ES2137999T3 (ru)
FI (1) FI113170B (ru)
GB (1) GB9220068D0 (ru)
GR (1) GR3032015T3 (ru)
HK (1) HK1012357A1 (ru)
HU (1) HU224071B1 (ru)
IL (1) IL107047A (ru)
MA (1) MA22980A1 (ru)
MX (1) MX9305844A (ru)
MY (1) MY110202A (ru)
NO (1) NO304688B1 (ru)
NZ (1) NZ256223A (ru)
OA (1) OA10138A (ru)
PH (1) PH31154A (ru)
PL (1) PL173450B1 (ru)
RO (1) RO113146B1 (ru)
RU (1) RU2128174C1 (ru)
SA (1) SA93140423B1 (ru)
SI (1) SI9300494A (ru)
SK (1) SK281227B6 (ru)
TW (1) TW409124B (ru)
UA (1) UA41903C2 (ru)
WO (1) WO1994006776A1 (ru)
ZA (1) ZA936962B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9220068D0 (en) * 1992-09-23 1992-11-04 Smithkline Beecham Corp Process
US5565577A (en) * 1992-09-23 1996-10-15 Smithkline Beecham Corporation Process for preparing 1-alkyaryl-2-alkyl-5-formylimidazole
EP1927590B1 (en) 2005-08-23 2011-07-20 Ube Industries, Ltd. Method for producing 1-substituted-5-acylimidazole compound
KR101472686B1 (ko) * 2013-07-09 2014-12-16 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 제조방법
CN103435617B (zh) * 2013-08-22 2016-04-27 南京华安药业有限公司 一种6,7-二氢-5H-吡咯并[1,2-a]咪唑-2-甲醛的合成方法
CN115894192A (zh) * 2022-12-05 2023-04-04 苏州诚和医药化学有限公司 一种2-溴丙二醛的合成方法、应用及2-溴丙二醛

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5671073A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd Imidazole derivative
US4482723A (en) * 1983-04-11 1984-11-13 Pfizer Inc. Process for preparation of 4-acetyl-2-substituted-imidazoles
US4602093A (en) * 1984-02-08 1986-07-22 Merck & Co., Inc. Novel substituted imidazoles, their preparation and use
DE3811621A1 (de) * 1988-04-07 1989-10-26 Merck Patent Gmbh Verfahren zur herstellung von 1h-imidazol-5-carbon-saeureestern oder -nitrilen und von pyrrol-3,4-carbonsaeureestern oder -nitrilen sowie verwendung der hergestellten verbindungen zur synthese von pilocarpin
US5234917A (en) * 1989-12-29 1993-08-10 Finkelstein Joseph A Substituted 5-(alkyl)carboxamide imidazoles
GB9220068D0 (en) * 1992-09-23 1992-11-04 Smithkline Beecham Corp Process

Also Published As

Publication number Publication date
AU4849693A (en) 1994-04-12
CA2145181C (en) 2004-11-16
AU676848B2 (en) 1997-03-27
KR100297505B1 (ko) 2001-10-24
BG62328B1 (bg) 1999-08-31
NO304688B1 (no) 1999-02-01
NO951094D0 (no) 1995-03-22
GR3032015T3 (en) 2000-03-31
HU9500837D0 (en) 1995-05-29
ES2137999T3 (es) 2000-01-01
CA2145181A1 (en) 1994-03-31
PL308173A1 (en) 1995-07-24
CN1092411A (zh) 1994-09-21
EP0662961A1 (en) 1995-07-19
MY110202A (en) 1998-02-28
WO1994006776A1 (en) 1994-03-31
MX9305844A (es) 1994-03-31
DK0662961T3 (da) 2000-04-17
NZ256223A (en) 1996-06-25
CZ282281B6 (cs) 1997-06-11
UA41903C2 (ru) 2001-10-15
EP0662961B1 (en) 1999-11-10
OA10138A (en) 1996-12-18
GB9220068D0 (en) 1992-11-04
PH31154A (en) 1998-03-20
TW409124B (en) 2000-10-21
RU2128174C1 (ru) 1999-03-27
DE69327007D1 (de) 1999-12-16
IL107047A0 (en) 1993-12-28
FI113170B (fi) 2004-03-15
CN1035613C (zh) 1997-08-13
IL107047A (en) 1998-04-05
AP9300565A0 (en) 1993-10-31
KR950703536A (ko) 1995-09-20
SA93140423B1 (ar) 2005-10-01
SI9300494A (en) 1994-03-31
CZ70895A3 (en) 1995-11-15
ATE186531T1 (de) 1999-11-15
ZA936962B (en) 1994-08-01
DE69327007T2 (de) 2000-04-20
JPH08501307A (ja) 1996-02-13
HK1012357A1 (en) 1999-07-30
SK37395A3 (en) 1995-08-09
BG99520A (bg) 1996-01-31
PL173450B1 (pl) 1998-03-31
EP0662961A4 (en) 1996-07-31
AP418A (en) 1995-10-24
BR9307201A (pt) 1999-03-30
RO113146B1 (ro) 1998-04-30
FI951350A0 (fi) 1995-03-22
SK281227B6 (sk) 2001-01-18
HU224071B1 (hu) 2005-05-30
MA22980A1 (fr) 1994-04-01
FI951350A (fi) 1995-03-22
HUT71335A (en) 1995-11-28
NO951094L (no) 1995-03-22

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Legal Events

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20100908