AP1967A - Thiazolidinone compounds as inhibitors of Hyak3 - Google Patents

Thiazolidinone compounds as inhibitors of Hyak3

Info

Publication number
AP1967A
AP1967A AP2005003304A AP2005003304A AP1967A AP 1967 A AP1967 A AP 1967A AP 2005003304 A AP2005003304 A AP 2005003304A AP 2005003304 A AP2005003304 A AP 2005003304A AP 1967 A AP1967 A AP 1967A
Authority
AP
ARIPO
Prior art keywords
hyak3
inhibitors
thiazolidinone compounds
thiazolidinone
compounds
Prior art date
Application number
AP2005003304A
Other languages
English (en)
Other versions
AP2005003304A0 (en
Inventor
Masaichi Hasegawa
Jun Tang
Hideyuki Sato
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of AP2005003304A0 publication Critical patent/AP2005003304A0/xx
Application granted granted Critical
Publication of AP1967A publication Critical patent/AP1967A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing alicyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AP2005003304A 2002-11-22 2003-11-18 Thiazolidinone compounds as inhibitors of Hyak3 AP1967A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42838402P 2002-11-22 2002-11-22
PCT/US2003/037658 WO2004047760A2 (en) 2002-11-22 2003-11-18 Novel chemical compounds

Publications (2)

Publication Number Publication Date
AP2005003304A0 AP2005003304A0 (en) 2005-06-30
AP1967A true AP1967A (en) 2009-03-10

Family

ID=32393394

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2005003304A AP1967A (en) 2002-11-22 2003-11-18 Thiazolidinone compounds as inhibitors of Hyak3

Country Status (30)

Country Link
US (1) US7767701B2 (de)
EP (1) EP1567112B1 (de)
JP (1) JP2006509765A (de)
KR (1) KR20050085115A (de)
CN (1) CN100579978C (de)
AP (1) AP1967A (de)
AR (1) AR045407A1 (de)
AT (1) ATE411302T1 (de)
AU (1) AU2003298693B2 (de)
BR (1) BR0316502A (de)
CA (1) CA2507256A1 (de)
CY (1) CY1108655T1 (de)
DE (1) DE60324178D1 (de)
DK (1) DK1567112T3 (de)
EA (1) EA008865B1 (de)
EC (1) ECSP055808A (de)
ES (1) ES2315566T3 (de)
IS (1) IS2659B (de)
MA (1) MA27701A1 (de)
MX (1) MXPA05005406A (de)
MY (1) MY140132A (de)
NO (1) NO20052928L (de)
NZ (1) NZ539873A (de)
OA (1) OA12963A (de)
PL (1) PL377564A1 (de)
PT (1) PT1567112E (de)
SI (1) SI1567112T1 (de)
TW (1) TWI309648B (de)
UA (1) UA80572C2 (de)
WO (1) WO2004047760A2 (de)

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USRE43833E1 (en) 2003-11-21 2012-11-27 Actelion Pharmaceuticals Ltd. Thiazolidin-4-one derivatives
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EP1718642A4 (de) * 2004-02-25 2010-11-24 Glaxosmithkline Llc Neue chemische verbindungen
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US7241893B2 (en) * 2004-09-17 2007-07-10 Hoffman-La Roche Inc. Thiazolinone 2-substituted quinolines
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BRPI0518164A (pt) 2004-10-14 2008-11-04 Hoffmann La Roche quinazolinilmetilenotiazolinonas como inibidores de cdk1
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EP1954136A4 (de) * 2005-11-08 2011-01-05 Glaxosmithkline Llc Neue chemische verbindungen
EP1993538A4 (de) * 2006-03-02 2010-05-19 Glaxosmithkline Llc Thiazolone als pi3-kinasehemmer
US20090023742A1 (en) * 2006-03-02 2009-01-22 Dashyant Dhanak Thiazolones for use as pi3 kinase inhibitors
KR100752757B1 (ko) * 2006-04-05 2007-08-29 한국과학기술연구원 2-페닐이미노-1,3-티아졸린을 포함하는 미백 조성물
EP2016062A2 (de) * 2006-04-25 2009-01-21 The Cleveland Clinic Foundation Rnase-l-aktivierende antivirale mittel
US8912340B2 (en) 2006-11-23 2014-12-16 Actelion Pharmaceuticals Ltd. Process for the preparation of 2-imino-thiazolidin-4-one derivatives
JP4669564B2 (ja) * 2006-11-23 2011-04-13 アクテリオン ファーマシューティカルズ リミテッド ２−イミノ−チアゾリジン−４−オン誘導体の製造のための新規な方法
US20100286041A1 (en) * 2007-03-22 2010-11-11 Smithkline Beecham Corporation (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4(5h)-one
CN101274918A (zh) * 2007-03-30 2008-10-01 中国科学院上海药物研究所 一类取代五元杂环化合物,其制备方法和医学用途
KR20120024619A (ko) 2009-04-20 2012-03-14 에스비아이 바이오테크 가부시키가이샤 티아졸리디논 유도체
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Patent Citations (1)

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FR1604530A (de) * 1967-06-06 1971-11-29

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 68, no. 19, 1968, Columbus, Ohio, US; abstract no.: 87228f *

Also Published As

Publication number Publication date
MA27701A1 (fr) 2006-01-02
SI1567112T1 (sl) 2009-02-28
AU2003298693B2 (en) 2010-09-30
TW200418819A (en) 2004-10-01
KR20050085115A (ko) 2005-08-29
MY140132A (en) 2009-11-30
NZ539873A (en) 2008-09-26
MXPA05005406A (es) 2005-08-03
TWI309648B (en) 2009-05-11
EA008865B1 (ru) 2007-08-31
EP1567112B1 (de) 2008-10-15
PL377564A1 (pl) 2006-02-06
CN1742010A (zh) 2006-03-01
US20060293338A1 (en) 2006-12-28
CN100579978C (zh) 2010-01-13
CY1108655T1 (el) 2014-04-09
ECSP055808A (es) 2005-09-20
ES2315566T3 (es) 2009-04-01
WO2004047760A2 (en) 2004-06-10
EA200500856A1 (ru) 2005-10-27
EP1567112A2 (de) 2005-08-31
WO2004047760A3 (en) 2004-10-21
AP2005003304A0 (en) 2005-06-30
CA2507256A1 (en) 2004-06-10
OA12963A (en) 2006-10-13
IS2659B (is) 2010-08-15
HK1083443A1 (en) 2006-07-07
IS7879A (is) 2005-06-02
AU2003298693A1 (en) 2004-06-18
EP1567112A4 (de) 2006-11-15
DK1567112T3 (da) 2009-02-09
AR045407A1 (es) 2005-10-26
NO20052928L (no) 2005-08-17
NO20052928D0 (no) 2005-06-15
UA80572C2 (en) 2007-10-10
JP2006509765A (ja) 2006-03-23
BR0316502A (pt) 2005-10-04
DE60324178D1 (de) 2008-11-27
US7767701B2 (en) 2010-08-03
ATE411302T1 (de) 2008-10-15
PT1567112E (pt) 2009-01-08

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