AU6330999A - Rhodanine derivatives for the treatment and prevention of metabolic bone disorders - Google Patents

Rhodanine derivatives for the treatment and prevention of metabolic bone disorders

Info

Publication number
AU6330999A
AU6330999A AU63309/99A AU6330999A AU6330999A AU 6330999 A AU6330999 A AU 6330999A AU 63309/99 A AU63309/99 A AU 63309/99A AU 6330999 A AU6330999 A AU 6330999A AU 6330999 A AU6330999 A AU 6330999A
Authority
AU
Australia
Prior art keywords
prevention
treatment
bone disorders
metabolic bone
rhodanine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU63309/99A
Inventor
Angelika Esswein
Eike Hoffmann
Konrad Honold
Klaus Kaluza
Wolfgang Schaefer
Christos Tsaklakidis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Publication of AU6330999A publication Critical patent/AU6330999A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU63309/99A 1998-09-30 1999-09-30 Rhodanine derivatives for the treatment and prevention of metabolic bone disorders Abandoned AU6330999A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98118538 1998-09-30
EP98118538 1998-09-30
PCT/EP1999/007250 WO2000018748A1 (en) 1998-09-30 1999-09-30 Rhodanine derivatives for the treatment and prevention of metabolic bone disorders

Publications (1)

Publication Number Publication Date
AU6330999A true AU6330999A (en) 2000-04-17

Family

ID=8232726

Family Applications (1)

Application Number Title Priority Date Filing Date
AU63309/99A Abandoned AU6330999A (en) 1998-09-30 1999-09-30 Rhodanine derivatives for the treatment and prevention of metabolic bone disorders

Country Status (2)

Country Link
AU (1) AU6330999A (en)
WO (1) WO2000018748A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI279401B (en) 1999-08-31 2007-04-21 Incyte San Diego Inc Heterocyclic derivatives for the treatment of diabetes and other diseases
WO2002072009A2 (en) 2001-03-07 2002-09-19 Maxia Pharmaceuticals, Inc. Heterocyclic derivatives for the treatment of cancer and other proliferative diseases
JP2004523571A (en) 2001-03-08 2004-08-05 マキシア・ファーマシューティカルズ・インコーポレイテッド RXR activating molecule
WO2003043998A1 (en) 2001-11-15 2003-05-30 Incyte San Diego Incorporated N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders, cancer, and other diseases
US7196108B2 (en) 2002-03-08 2007-03-27 Incyte San Diego Inc. Bicyclic heterocycles for the treatment of diabetes and other diseases
US7102000B2 (en) 2002-03-08 2006-09-05 Incyte San Diego Inc. Heterocyclic amide derivatives for the treatment of diabetes and other diseases
EP1507772A1 (en) * 2002-05-17 2005-02-23 QLT, Inc. Methods of using thiazolidinedithione derivatives
BR0312752A (en) * 2002-07-10 2005-04-26 Applied Research Systems Azolidinone-vinyl fused benzene derivatives
US20060276520A1 (en) * 2002-11-13 2006-12-07 Rigel Pharmaceuticals, Inc. Rhodanine derivatives and pharmaceutical compositions containing them
AU2003298693B2 (en) 2002-11-22 2010-09-30 Smithkline Beecham Corporation Novel chemical compounds
FI20041129A0 (en) * 2004-08-30 2004-08-30 Ctt Cancer Targeting Tech Oy Thioxothiazolidinone compounds for use as drugs
DE102005022182A1 (en) * 2005-05-09 2006-11-16 Combinature Biopharm Ag Modulators of the PDZ domain
PE20070083A1 (en) 2005-06-08 2007-01-27 Smithkline Beecham Corp (5Z) -5- (6-QUINOXALINYL METHYLIDENE) -2 - [(2,6-DICHLOROPHENYL) AMINO] -1,3-THIAZOL-4 (5H) -ONE
CN107382996B (en) * 2017-06-30 2020-11-06 中国农业大学 Specific inhibition plant plasma membrane H+-ATPase compound and preparation method and application thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2196797A1 (en) * 1972-08-25 1974-03-22 Aries Robert Parasiticidal 5-styryl rhodanines - prepd. by condensation of a subst ben-aldehyde and a 5-methyl rhodanine
PT83152B (en) * 1985-08-09 1989-03-30 Lilly Co Eli PROCESS FOR THE PREPARATION OF DI-T-BUTYLPHENOIC COMPOUNDS
KR870006897A (en) * 1986-01-07 1987-08-13 모리오까 시게오 Heterocyclic Compounds, Methods of Making the Same, and Pharmaceutical Compositions Containing the Same
US4897406A (en) * 1987-11-13 1990-01-30 Nisshin Flour Milling Co., Ltd. Rhodanine derivatives and pharmaceutical compositions
IE62214B1 (en) * 1988-05-25 1995-01-11 Warner Lambert Co Arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflammatory agents
ATE139531T1 (en) * 1989-04-07 1996-07-15 Lilly Co Eli ARYL-SUBSTITUTED RHODANEINE DERIVATIVES
US5116855A (en) * 1989-05-19 1992-05-26 Nisshin Flour Milling Co., Ltd. Rhodanine derivatives and pharmaceutical compositions
IL96654A (en) * 1989-12-21 1995-06-29 Lilly Co Eli Hydroxybenzyl substituted sulfur containing heterocyclic derivatives their preparation and pharmaceutical compositions containing them
JPH05306224A (en) * 1992-04-24 1993-11-19 Wakamoto Pharmaceut Co Ltd Dopamine beta-hydroxylase inhibitor
CZ181493A3 (en) * 1992-09-10 1994-03-16 Lilly Co Eli The use of rhodanine derivative for the preparation of a pharmaceutical composition reducing level of sugar in blood and for treating alzheimer's disease
JP2845743B2 (en) * 1992-12-28 1999-01-13 三菱化学株式会社 New naphthalene derivatives
US6251928B1 (en) * 1994-03-16 2001-06-26 Eli Lilly And Company Treatment of alzheimer's disease employing inhibitors of cathepsin D
US5476865A (en) * 1994-07-06 1995-12-19 Eli Lilly And Company Methods of inhibiting bone loss
IL117208A0 (en) * 1995-02-23 1996-06-18 Nissan Chemical Ind Ltd Indole type thiazolidines
EP0783888A1 (en) * 1995-12-26 1997-07-16 Sankyo Company Limited Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis
GB9614402D0 (en) * 1996-07-09 1996-09-04 Smithkline Beecham Spa Novel compounds

Also Published As

Publication number Publication date
WO2000018748A1 (en) 2000-04-06

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase