ZA9711437B - Prevention of loss and restoration of bone mass by certain prostaglandin agonists - Google Patents

Prevention of loss and restoration of bone mass by certain prostaglandin agonists

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Publication number
ZA9711437B
ZA9711437B ZA9711437A ZA9711437A ZA9711437B ZA 9711437 B ZA9711437 B ZA 9711437B ZA 9711437 A ZA9711437 A ZA 9711437A ZA 9711437 A ZA9711437 A ZA 9711437A ZA 9711437 B ZA9711437 B ZA 9711437B
Authority
ZA
South Africa
Prior art keywords
restoration
prevention
loss
bone mass
prostaglandin agonists
Prior art date
Application number
ZA9711437A
Other languages
English (en)
Inventor
Kimberly O'keefe Cameron
Hua Zhu Ke
Bruce Allen Lefker
Robert Louis Rosati
David Duane Thompson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA9711437B publication Critical patent/ZA9711437B/xx

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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
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SA05260205B1 (ar) 2008-05-27
NZ335736A (en) 2001-01-26
NO313668B1 (no) 2002-11-11
BG103593A (en) 2000-03-31
EP0946501B1 (fr) 2006-05-31
TR199901366T2 (xx) 1999-09-21
MA24425A1 (fr) 1998-07-01
HRP970696A2 (en) 1998-10-31
UA59384C2 (uk) 2003-09-15
HUP0000739A3 (en) 2001-02-28
CZ300107B6 (cs) 2009-02-11
IS5055A (is) 1999-05-21
IL130306A0 (en) 2000-06-01
IS2389B (is) 2008-08-15
EA003529B1 (ru) 2003-06-26
SA97180721A (ar) 2005-12-03
US20040176461A1 (en) 2004-09-09
AU721260B2 (en) 2000-06-29
EP0946501A1 (fr) 1999-10-06
AU4720097A (en) 1998-07-17
AP9701166A0 (en) 1998-01-31
ATE327976T1 (de) 2006-06-15
DK0946501T3 (da) 2006-10-02
HUP0000739A2 (hu) 2000-09-28
WO1998028264A1 (fr) 1998-07-02
AP1041A (en) 2002-02-01
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SA97180721B1 (ar) 2006-04-22
JP2000514827A (ja) 2000-11-07
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US6649657B2 (en) 2003-11-18
HN1997000161A (es) 1998-10-22
EA005161B1 (ru) 2004-12-30
DE69736007D1 (de) 2006-07-06
BR9714155A (pt) 2000-05-02
CA2275479A1 (fr) 1998-07-02
SI0946501T1 (sl) 2006-10-31
US20020016368A1 (en) 2002-02-07
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OA11065A (en) 2002-11-15
EA199900474A1 (ru) 2000-02-28
SK78299A3 (en) 2000-10-09
PE47499A1 (es) 1999-05-13
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PL192670B1 (pl) 2006-11-30
US6998423B2 (en) 2006-02-14
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GT199700141A (es) 1999-06-22
YU32799A (sh) 2002-06-19
US20030105092A1 (en) 2003-06-05
JP2005068154A (ja) 2005-03-17
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JP4067105B2 (ja) 2008-03-26

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