EA199900474A1 - Предупреждение потери и восстановление костной массы некоторыми агонистами простагландина - Google Patents

Предупреждение потери и восстановление костной массы некоторыми агонистами простагландина

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Publication number
EA199900474A1
EA199900474A1 EA199900474A EA199900474A EA199900474A1 EA 199900474 A1 EA199900474 A1 EA 199900474A1 EA 199900474 A EA199900474 A EA 199900474A EA 199900474 A EA199900474 A EA 199900474A EA 199900474 A1 EA199900474 A1 EA 199900474A1
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EA
Eurasian Patent Office
Prior art keywords
agentists
prostaglandina
restoration
prevention
loss
Prior art date
Application number
EA199900474A
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English (en)
Other versions
EA003529B1 (ru
Inventor
Кимберли О'Киф Кэмерон
Хуа Зу Ки
Брюс Аллен Лефкер
Роберт Луис Росэйти
Дейвид Дуэйн Томпсон
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Пфайзер Инк.
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Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Publication of EA199900474A1 publication Critical patent/EA199900474A1/ru
Publication of EA003529B1 publication Critical patent/EA003529B1/ru

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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
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Abstract

Агонисты простагландина формулы (I), в которой, например, А представляет собой сульфонильную или ацильную группу, В представляет собой N или CH, M включает в себя кольцо, а K и Q являются связывающими группами, способы применения таких агонистов простагландина, фармацевтические композиции, содержащие такие агонисты простагландина и наборы лекарственных средств, которые можно применять для лечения костных расстройств, включая остеопороз.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199900474A 1996-12-20 1997-11-10 Предупреждение потери и восстановление костной массы некоторыми агонистами простагландина EA003529B1 (ru)

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TWI242560B (en) 2005-11-01
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HN1997000161A (es) 1998-10-22
US6998423B2 (en) 2006-02-14
US20020016368A1 (en) 2002-02-07
AP9701166A0 (en) 1998-01-31
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UY24816A1 (es) 2000-09-29
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PL192670B1 (pl) 2006-11-30
HUP0000739A2 (hu) 2000-09-28
IL130306A (en) 2008-12-29
CZ223399A3 (cs) 2000-08-16
EA005161B1 (ru) 2004-12-30
NO992996L (no) 1999-08-18
OA11065A (en) 2002-11-15
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KR100311566B1 (ko) 2001-11-03
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YU32799A (sh) 2002-06-19
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NO992996D0 (no) 1999-06-18
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