ZA825512B - New amino compounds derived from pyridazine,active on the central nervous system - Google Patents

New amino compounds derived from pyridazine,active on the central nervous system

Info

Publication number
ZA825512B
ZA825512B ZA825512A ZA825512A ZA825512B ZA 825512 B ZA825512 B ZA 825512B ZA 825512 A ZA825512 A ZA 825512A ZA 825512 A ZA825512 A ZA 825512A ZA 825512 B ZA825512 B ZA 825512B
Authority
ZA
South Africa
Prior art keywords
pyridazine
active
nervous system
central nervous
compounds derived
Prior art date
Application number
ZA825512A
Other languages
English (en)
Inventor
Jean-Paul Kan
Kathleen Biziere
Camille Georges Wermuth
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ZA825512B publication Critical patent/ZA825512B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA825512A 1981-08-07 1982-07-30 New amino compounds derived from pyridazine,active on the central nervous system ZA825512B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8115380A FR2510998B1 (fr) 1981-08-07 1981-08-07 Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent

Publications (1)

Publication Number Publication Date
ZA825512B true ZA825512B (en) 1983-06-29

Family

ID=9261294

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA825512A ZA825512B (en) 1981-08-07 1982-07-30 New amino compounds derived from pyridazine,active on the central nervous system
ZA825513A ZA825513B (en) 1981-08-07 1982-07-30 New derivatives of pyridazine active on the central nervous system

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA825513A ZA825513B (en) 1981-08-07 1982-07-30 New derivatives of pyridazine active on the central nervous system

Country Status (30)

Country Link
US (1) US4508720A (pm)
EP (2) EP0072726B1 (pm)
JP (2) JPS5877867A (pm)
KR (2) KR890001569B1 (pm)
AR (2) AR231637A1 (pm)
AT (2) ATE18216T1 (pm)
AU (2) AU548930B2 (pm)
CA (2) CA1174240A (pm)
CS (2) CS229941B2 (pm)
DD (2) DD202549A5 (pm)
DE (2) DE3262671D1 (pm)
DK (2) DK148537C (pm)
EG (2) EG15747A (pm)
ES (2) ES514795A0 (pm)
FI (2) FI72969C (pm)
FR (1) FR2510998B1 (pm)
GR (2) GR76430B (pm)
HU (2) HU190028B (pm)
IE (2) IE53387B1 (pm)
IL (2) IL66408A (pm)
MA (2) MA19562A1 (pm)
NO (2) NO157861C (pm)
NZ (2) NZ201520A (pm)
OA (2) OA07176A (pm)
PH (1) PH18545A (pm)
PL (2) PL137199B1 (pm)
PT (2) PT75350B (pm)
SU (2) SU1140685A3 (pm)
YU (2) YU172082A (pm)
ZA (2) ZA825512B (pm)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
CA1218655A (en) * 1983-01-28 1987-03-03 Kathleen Biziere Process for the preparation of pyridazine derivatives having a psychotropic action
US4628088A (en) * 1984-07-17 1986-12-09 Eli Lilly And Company Preparation of substituted pyridazines
DE3664772D1 (en) * 1985-01-14 1989-09-07 Boehringer Ingelheim Kg 12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use
FR2642648B1 (fr) * 1989-02-07 1991-06-21 Sanofi Sa Utilisation de derives d'alkyl-5 pyridazine comme medicaments actifs sur le systeme cholinergique
US5631255A (en) * 1989-02-07 1997-05-20 Sanofi Pyridazine derivatives
FR2642754B1 (fr) * 1989-02-07 1991-05-24 Sanofi Sa Nouveaux derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant
FR2654727B1 (fr) * 1989-11-17 1992-03-27 Sanofi Sa Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
US5461053A (en) * 1989-02-07 1995-10-24 Sanofi Pyridazine derivatives
FR2665442B1 (fr) * 1990-07-31 1992-12-04 Sanofi Sa Derives d'alkyl-6 pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
PT93060B (pt) 1989-02-07 1995-12-29 Sanofi Sa Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem
FR2663326B2 (fr) * 1989-11-17 1992-10-16 Sanofi Sa Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2676444B1 (fr) * 1991-05-16 1995-03-10 Sanofi Elf Nouveaux derives d'amino-3 pyridazines actifs sur le systeme nerveux central, procede de preparation et compositions pharmaceutiques en contenant.
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
US20030176437A1 (en) * 2001-08-31 2003-09-18 D.M. Watterson Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
AU2003246979B8 (en) * 2002-08-13 2009-08-06 Merck Sharp & Dohme Limited Phenylpyridazine derivatives as ligands for GABA receptors
WO2006050359A2 (en) * 2004-11-02 2006-05-11 Northwestern University Pyridazine compounds and methods
AU2005302225B2 (en) 2004-11-02 2012-05-24 Centre National De La Recherche Scientifique Pyridazine compounds, compositions and methods
MX2008013843A (es) * 2006-04-28 2008-11-10 Univ Northwestern Formulaciones que contienen compuestos de piridazina para tratar enfermedades neuroinflamatorias.
WO2007127474A2 (en) * 2006-04-28 2007-11-08 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
EP2015751A2 (en) * 2006-04-28 2009-01-21 Northwestern University Salts of pyridazine compounds
RU2555969C1 (ru) * 2014-07-09 2015-07-10 Юлия Алексеевна Щепочкина Керамическая масса для изготовления облицовочной плитки

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives

Also Published As

Publication number Publication date
PT75351B (fr) 1984-08-01
NZ201520A (en) 1985-04-30
US4508720A (en) 1985-04-02
AU548931B2 (en) 1986-01-09
PT75350B (fr) 1984-08-01
EP0074863A1 (fr) 1983-03-23
DK148795B (da) 1985-09-30
IL66408A0 (en) 1982-11-30
FI822747A0 (fi) 1982-08-06
IE821778L (en) 1983-02-07
OA07175A (fr) 1984-04-30
DK354482A (da) 1983-02-08
YU172082A (en) 1985-03-20
JPH0459312B2 (pm) 1992-09-21
FR2510998A1 (fr) 1983-02-11
HU189166B (en) 1986-06-30
NO822509L (no) 1983-02-08
AR231441A1 (es) 1984-11-30
ES8305737A1 (es) 1983-04-16
FI72968C (fi) 1987-08-10
EP0074863B1 (fr) 1986-02-26
OA07176A (fr) 1984-04-30
JPS5877868A (ja) 1983-05-11
NO157861B (no) 1988-02-22
NO157102C (no) 1988-01-20
YU171882A (en) 1985-03-20
PL237809A1 (en) 1983-02-28
PT75351A (fr) 1982-08-01
CS229941B2 (en) 1984-07-16
ATE12227T1 (de) 1985-04-15
PL237808A1 (en) 1983-02-28
AU8655482A (en) 1983-02-10
DD202715A5 (de) 1983-09-28
PL130647B1 (en) 1984-08-31
FI72969C (fi) 1987-08-10
FI822747L (fi) 1983-02-08
DD202549A5 (de) 1983-09-21
FR2510998B1 (fr) 1986-01-10
KR880001624B1 (ko) 1988-09-02
ES8305738A1 (es) 1983-04-16
ZA825513B (en) 1983-06-29
DK354382A (da) 1983-02-08
EP0072726A1 (fr) 1983-02-23
EG15747A (en) 1986-06-30
CA1179346A (en) 1984-12-11
ATE18216T1 (de) 1986-03-15
FI822748A0 (fi) 1982-08-06
DE3269383D1 (en) 1986-04-03
EG15788A (en) 1986-09-30
KR840001145A (ko) 1984-03-28
DK148537B (da) 1985-07-29
KR890001569B1 (ko) 1989-05-08
PH18545A (en) 1985-08-09
DK148537C (da) 1986-01-13
HU190028B (en) 1986-08-28
MA19562A1 (fr) 1983-04-01
SU1140685A3 (ru) 1985-02-15
NZ201518A (en) 1985-04-30
MA19560A1 (fr) 1983-04-01
NO157102B (no) 1987-10-12
ES514794A0 (es) 1983-04-16
IE53387B1 (en) 1988-10-26
ES514795A0 (es) 1983-04-16
CS229940B2 (en) 1984-07-16
NO822510L (no) 1983-02-08
DK148795C (da) 1986-03-10
IL66408A (en) 1985-12-31
FI72969B (fi) 1987-04-30
GR76430B (pm) 1984-08-10
PT75350A (fr) 1982-08-01
IE53388B1 (en) 1988-10-26
IE821779L (en) 1983-02-07
CA1174240A (en) 1984-09-11
DE3262671D1 (en) 1985-04-25
AU8655382A (en) 1983-02-10
KR840001159A (ko) 1984-03-28
AU548930B2 (en) 1986-01-09
GR76429B (pm) 1984-08-10
SU1138024A3 (ru) 1985-01-30
IL66409A (en) 1985-09-29
EP0072726B1 (fr) 1985-03-20
AR231637A1 (es) 1985-01-31
JPS5877867A (ja) 1983-05-11
IL66409A0 (en) 1982-11-30
PL137199B1 (en) 1986-05-31
NO157861C (no) 1988-06-01
FI72968B (fi) 1987-04-30
FI822748L (fi) 1983-02-08

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