ZA201405870B - Polymorphic forms of (s)-2-(1-(9h-purin-6-ylamino)-5-fluoro-3-phenylquinazolin-4(3h)-one - Google Patents

Polymorphic forms of (s)-2-(1-(9h-purin-6-ylamino)-5-fluoro-3-phenylquinazolin-4(3h)-one

Info

Publication number
ZA201405870B
ZA201405870B ZA2014/05870A ZA201405870A ZA201405870B ZA 201405870 B ZA201405870 B ZA 201405870B ZA 2014/05870 A ZA2014/05870 A ZA 2014/05870A ZA 201405870 A ZA201405870 A ZA 201405870A ZA 201405870 B ZA201405870 B ZA 201405870B
Authority
ZA
South Africa
Prior art keywords
phenylquinazolin
purin
ylamino
fluoro
polymorphic forms
Prior art date
Application number
ZA2014/05870A
Other languages
English (en)
Inventor
Jerry B Evarts
Fang Wang
Duong Tran
Keiko Sujino
Bing Shi
Michael Gerber
Ernest Carra
Original Assignee
Gilead Calistoga Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49117265&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA201405870(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gilead Calistoga Llc filed Critical Gilead Calistoga Llc
Publication of ZA201405870B publication Critical patent/ZA201405870B/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
ZA2014/05870A 2012-03-05 2014-08-11 Polymorphic forms of (s)-2-(1-(9h-purin-6-ylamino)-5-fluoro-3-phenylquinazolin-4(3h)-one ZA201405870B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261606870P 2012-03-05 2012-03-05
PCT/US2013/029157 WO2013134288A1 (en) 2012-03-05 2013-03-05 Polymorphic forms of (s)-2-(1-(9h-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3h)-one

Publications (1)

Publication Number Publication Date
ZA201405870B true ZA201405870B (en) 2015-11-25

Family

ID=49117265

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2014/05870A ZA201405870B (en) 2012-03-05 2014-08-11 Polymorphic forms of (s)-2-(1-(9h-purin-6-ylamino)-5-fluoro-3-phenylquinazolin-4(3h)-one

Country Status (31)

Country Link
US (3) US8865730B2 (enExample)
EP (1) EP2834241B1 (enExample)
JP (2) JP2015509537A (enExample)
KR (1) KR20140133590A (enExample)
CN (2) CN106146506A (enExample)
AP (1) AP2014007875A0 (enExample)
AR (1) AR090253A1 (enExample)
AU (1) AU2013203620B2 (enExample)
BR (1) BR112014021935A2 (enExample)
CA (1) CA2864305C (enExample)
CL (1) CL2014002358A1 (enExample)
CO (1) CO7071131A2 (enExample)
CR (1) CR20140460A (enExample)
EA (3) EA025407B1 (enExample)
EC (1) ECSP14020478A (enExample)
ES (1) ES2848273T3 (enExample)
IN (1) IN2014DN07105A (enExample)
MA (1) MA37379A1 (enExample)
MD (1) MD20140100A2 (enExample)
MX (1) MX2014010656A (enExample)
NZ (1) NZ629684A (enExample)
PE (1) PE20141792A1 (enExample)
PH (1) PH12014501920A1 (enExample)
PL (1) PL2834241T3 (enExample)
PT (1) PT2834241T (enExample)
SG (1) SG11201405446PA (enExample)
SI (1) SI2834241T1 (enExample)
TW (1) TW201350486A (enExample)
UY (1) UY34656A (enExample)
WO (1) WO2013134288A1 (enExample)
ZA (1) ZA201405870B (enExample)

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CZ2015575A3 (cs) * 2015-08-26 2017-03-08 Zentiva, K.S. Soli 5-fluoro-3-fenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]quinazolin-4-onu a jejich příprava
CN106565716B (zh) * 2015-10-10 2021-06-15 上海创诺制药有限公司 一种Idelalisib晶型A及其制备方法
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CN107573345B (zh) * 2017-09-12 2020-01-10 浙江乐普药业股份有限公司 一种艾代拉利司及其中间体的制备方法
CN109575027A (zh) * 2017-09-29 2019-04-05 宁波爱诺医药科技有限公司 一种抗肿瘤药物艾德力布的一水合物及其制备方法
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