ZA200408506B - 5HT2c receptor modulators - Google Patents

5HT2c receptor modulators Download PDF

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Publication number
ZA200408506B
ZA200408506B ZA200408506A ZA200408506A ZA200408506B ZA 200408506 B ZA200408506 B ZA 200408506B ZA 200408506 A ZA200408506 A ZA 200408506A ZA 200408506 A ZA200408506 A ZA 200408506A ZA 200408506 B ZA200408506 B ZA 200408506B
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ZA
South Africa
Prior art keywords
benzazepine
tetrahydro
methyl
methoxy
bromo
Prior art date
Application number
ZA200408506A
Other languages
English (en)
Inventor
Brian Smith
Jeffrey Smith
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29255581&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200408506(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Publication of ZA200408506B publication Critical patent/ZA200408506B/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
ZA200408506A 2002-04-12 2004-10-20 5HT2c receptor modulators ZA200408506B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US37205802P 2002-04-12 2002-04-12
US40549502P 2002-08-23 2002-08-23
US43460702P 2002-12-18 2002-12-18
US10/410,991 US6953787B2 (en) 2002-04-12 2003-04-10 5HT2C receptor modulators

Publications (1)

Publication Number Publication Date
ZA200408506B true ZA200408506B (en) 2006-06-28

Family

ID=29255581

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200408506A ZA200408506B (en) 2002-04-12 2004-10-20 5HT2c receptor modulators

Country Status (29)

Country Link
US (11) US6953787B2 (de)
EP (4) EP1411881B9 (de)
JP (5) JP4155926B2 (de)
KR (3) KR100908166B1 (de)
CN (5) CN101486679A (de)
AT (1) ATE294781T1 (de)
AU (1) AU2003221866B2 (de)
BR (2) BR122017023795B8 (de)
CA (1) CA2481723C (de)
CR (2) CR7503A (de)
DE (1) DE60300610T2 (de)
DK (1) DK1411881T3 (de)
ES (2) ES2242165T3 (de)
GE (1) GEP20074197B (de)
HK (1) HK1064095A1 (de)
IL (1) IL164162A0 (de)
IS (1) IS2134B (de)
MX (1) MXPA04009965A (de)
MY (1) MY141476A (de)
NO (1) NO323528B1 (de)
NZ (1) NZ535381A (de)
PL (4) PL231405B1 (de)
PT (1) PT1411881E (de)
RU (1) RU2317982C2 (de)
SI (1) SI1411881T1 (de)
TW (1) TWI252105B (de)
UA (1) UA77788C2 (de)
WO (1) WO2003086306A2 (de)
ZA (1) ZA200408506B (de)

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TWI329111B (en) 2002-05-24 2010-08-21 X Ceptor Therapeutics Inc Azepinoindole and pyridoindole derivatives as pharmaceutical agents
US7595311B2 (en) 2002-05-24 2009-09-29 Exelixis, Inc. Azepinoindole derivatives as pharmaceutical agents
MXPA05006567A (es) 2002-12-20 2005-08-16 Glaxo Group Ltd Derivados de benzazepina para el tratamiento de trastornos neurologicos.
CN101792417A (zh) * 2003-06-17 2010-08-04 艾尼纳制药公司 用于治疗5ht2c受体相关疾病的苯并氮杂卓衍生物
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DE602004017206D1 (de) * 2003-10-23 2008-11-27 Hoffmann La Roche Benzazepin-derivate als mao-b-hemmer
PL1720836T3 (pl) 2004-02-25 2014-09-30 Lilly Co Eli 6-podstawione 2,3,4,5-tetrahydro-1h-benzo [d]azepiny jako agoniści receptora 5-ht2c
EP2248524A3 (de) 2004-08-25 2011-03-09 Takeda Pharmaceutical Company Limited Mittel zur prävention/behandlung von stressbedingter harninkontinenz und vorsorgeuntersuchungsverfahren dafür
ATE507832T1 (de) * 2004-09-03 2011-05-15 Athersys Inc Trizyklische heteroaryl-piperazine, pyrrolidine und azetidine als serotonin-rezeptor-modulatoren
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WO2006044762A2 (en) * 2004-10-15 2006-04-27 Bayer Pharmaceuticals Corporation Tetrahydro-5h-pyrimido[4,5-d]azepine derivatives useful for the treatment of diseases associated with the 5-ht2c receptor
BRPI0519013A2 (pt) * 2004-12-13 2009-11-03 Lilly Co Eli composto ou esteroisÈmeros únicos, misturas de esteroisÈmeros, sais, tautÈmeros ou pró-drogas destes farmaceuticamente aceitáveis, composição farmacêutica, e, uso de um composto
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PT1833473E (pt) 2004-12-23 2009-12-17 Arena Pharm Inc Composições de modulador de receptor 5ht2c e métodos de utilização
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