ATE507832T1 - Trizyklische heteroaryl-piperazine, pyrrolidine und azetidine als serotonin-rezeptor-modulatoren - Google Patents
Trizyklische heteroaryl-piperazine, pyrrolidine und azetidine als serotonin-rezeptor-modulatorenInfo
- Publication number
- ATE507832T1 ATE507832T1 AT05794345T AT05794345T ATE507832T1 AT E507832 T1 ATE507832 T1 AT E507832T1 AT 05794345 T AT05794345 T AT 05794345T AT 05794345 T AT05794345 T AT 05794345T AT E507832 T1 ATE507832 T1 AT E507832T1
- Authority
- AT
- Austria
- Prior art keywords
- azetidines
- pyrrolidines
- piperazines
- receptor modulators
- serotonin receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Addiction (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60714204P | 2004-09-03 | 2004-09-03 | |
PCT/US2005/031306 WO2006028961A2 (en) | 2004-09-03 | 2005-09-01 | Tricyclic heteroaryl piperazines, pyrrolidines and azetidines as serotonin receptor modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE507832T1 true ATE507832T1 (de) | 2011-05-15 |
Family
ID=36036866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05794345T ATE507832T1 (de) | 2004-09-03 | 2005-09-01 | Trizyklische heteroaryl-piperazine, pyrrolidine und azetidine als serotonin-rezeptor-modulatoren |
Country Status (9)
Country | Link |
---|---|
US (2) | US7423056B2 (de) |
EP (1) | EP1796663B1 (de) |
JP (1) | JP4960235B2 (de) |
AR (1) | AR050624A1 (de) |
AT (1) | ATE507832T1 (de) |
DE (1) | DE602005027861D1 (de) |
DK (1) | DK1796663T3 (de) |
TW (1) | TWI406866B (de) |
WO (1) | WO2006028961A2 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4960235B2 (ja) * | 2004-09-03 | 2012-06-27 | アサーシス, インク. | セロトニン受容体調節剤としての三環ヘテロアリールのピペラジン化合物、ピロリジン化合物およびアゼチジン化合物 |
JP5007988B2 (ja) * | 2005-10-27 | 2012-08-22 | 国立大学法人名古屋大学 | 多環縮環化合物およびそれらの製造法ならびに多環縮環化合物を用いる有機電界発光素子 |
WO2007132841A1 (ja) | 2006-05-16 | 2007-11-22 | Takeda Pharmaceutical Company Limited | 縮合複素環化合物およびその用途 |
CN101230058A (zh) * | 2007-01-23 | 2008-07-30 | 上海恒瑞医药有限公司 | 双环氮杂烷类衍生物、其制备方法及其在医药上的用途 |
US20100266504A1 (en) | 2007-11-15 | 2010-10-21 | Takahiro Matsumoto | Condensed pyridine derivative and use thereof |
WO2009094866A1 (fr) | 2008-01-23 | 2009-08-06 | Shanghai Hengrui Pharmaceutical Co., Ltd. | Dérivés de dicycloazaalcane, leurs procédés de préparation et utilisations médicales |
US8546377B2 (en) | 2009-04-23 | 2013-10-01 | Abbvie Inc. | Modulators of 5-HT receptors and methods of use thereof |
US8518933B2 (en) | 2009-04-23 | 2013-08-27 | Abbvie Inc. | Modulators of 5-HT receptors and methods of use thereof |
WO2011071136A1 (ja) | 2009-12-11 | 2011-06-16 | アステラス製薬株式会社 | 線維筋痛症治療剤 |
WO2012120055A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US8901114B2 (en) | 2011-03-08 | 2014-12-02 | Sanofi | Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof |
WO2012120054A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
EP2683704B1 (de) | 2011-03-08 | 2014-12-17 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US9937002B2 (en) | 2011-03-08 | 2018-04-10 | Nexus Control Systems, Llc | Ablation catheter system with safety features |
KR101273566B1 (ko) * | 2011-09-05 | 2013-06-11 | 한국과학기술연구원 | 신규한 아제티딘 유도체 및 이를 함유하는 항우울제 조성물 |
CN102827064B (zh) * | 2012-08-14 | 2014-01-29 | 华东师范大学 | 一种氮杂双环[3.3.0]辛烷衍生物的合成方法 |
US20210052600A1 (en) | 2017-12-27 | 2021-02-25 | Takeda Pharmaceutical Company Limited | Therapeutic agents for stress urinary incontinence and incotinence of feces |
CN116283899A (zh) * | 2022-12-28 | 2023-06-23 | 南京林业大学 | 一种3-全氟烷基苯并噻吩[b]环戊烯酮化合物及其合成方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA821020B (en) * | 1981-02-18 | 1983-10-26 | Thomae Gmbh Dr K | Azepine derivatives, process for their preparation and pharmaceutical compositions thereof |
GB8800891D0 (en) * | 1988-01-15 | 1988-02-17 | Lilly Industries Ltd | Pharmaceutical compounds |
WO1993013105A1 (fr) | 1991-12-26 | 1993-07-08 | Yoshitomi Pharmaceutical Industries, Ltd. | Compose de thiophene condense et utilisation pharmaceutique de ce compose |
FR2725792A1 (fr) | 1994-10-13 | 1996-04-19 | Centre Nat Etd Spatiales | Procede pour evaluer des effets non-euclidiens affectant une image obtenue avec un radar spatial, et satellite pour sa mise en oeuvre |
DE69820989T2 (de) * | 1997-01-08 | 2004-12-09 | F. Hoffmann-La Roche Ag | Tricyclische benz[e]isoindole und benz[h]isochinoline |
AU727654B2 (en) * | 1997-06-13 | 2000-12-21 | Yamanouchi Pharmaceutical Co., Ltd. | Tricyclic pyrazole derivative |
WO1999065911A1 (en) | 1998-06-16 | 1999-12-23 | Ortho-Mcneil Pharmaceutical, Inc. | OCTAHYDROPYRROLO-[3,4-c]CARBAZOLES USEFUL AS ANALGESIC AGENTS |
JPWO2002074746A1 (ja) * | 2001-03-16 | 2004-07-08 | 山之内製薬株式会社 | ベンゾアゼピン誘導体 |
GB0118892D0 (en) * | 2001-08-02 | 2001-09-26 | Vernalis Res Ltd | Method of treatment |
WO2003051883A1 (fr) | 2001-12-18 | 2003-06-26 | Kyowa Hakko Kogyo Co., Ltd. | Derive d'indole |
US6953787B2 (en) * | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators |
JP4960235B2 (ja) * | 2004-09-03 | 2012-06-27 | アサーシス, インク. | セロトニン受容体調節剤としての三環ヘテロアリールのピペラジン化合物、ピロリジン化合物およびアゼチジン化合物 |
-
2005
- 2005-09-01 JP JP2007530395A patent/JP4960235B2/ja not_active Expired - Fee Related
- 2005-09-01 DE DE602005027861T patent/DE602005027861D1/de active Active
- 2005-09-01 DK DK05794345.8T patent/DK1796663T3/da active
- 2005-09-01 WO PCT/US2005/031306 patent/WO2006028961A2/en active Application Filing
- 2005-09-01 AT AT05794345T patent/ATE507832T1/de not_active IP Right Cessation
- 2005-09-01 EP EP05794345A patent/EP1796663B1/de not_active Not-in-force
- 2005-09-01 US US11/217,991 patent/US7423056B2/en not_active Expired - Fee Related
- 2005-09-02 AR ARP050103681A patent/AR050624A1/es not_active Application Discontinuation
- 2005-09-05 TW TW094130443A patent/TWI406866B/zh not_active IP Right Cessation
-
2008
- 2008-08-05 US US12/221,668 patent/US7981919B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US7981919B2 (en) | 2011-07-19 |
AR050624A1 (es) | 2006-11-08 |
JP4960235B2 (ja) | 2012-06-27 |
TWI406866B (zh) | 2013-09-01 |
DK1796663T3 (da) | 2011-08-15 |
JP2008512377A (ja) | 2008-04-24 |
EP1796663A2 (de) | 2007-06-20 |
US7423056B2 (en) | 2008-09-09 |
WO2006028961A3 (en) | 2006-12-28 |
US20090069365A1 (en) | 2009-03-12 |
WO2006028961A2 (en) | 2006-03-16 |
EP1796663B1 (de) | 2011-05-04 |
US20060079567A1 (en) | 2006-04-13 |
DE602005027861D1 (de) | 2011-06-16 |
EP1796663A4 (de) | 2009-08-05 |
TW200621787A (en) | 2006-07-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |