YU38795A - Kortikotropinski otpuštajući faktor antagonisti, postupci za njihovo dobijanje i njihove farmaceutske smese - Google Patents
Kortikotropinski otpuštajući faktor antagonisti, postupci za njihovo dobijanje i njihove farmaceutske smeseInfo
- Publication number
- YU38795A YU38795A YU38795A YU38795A YU38795A YU 38795 A YU38795 A YU 38795A YU 38795 A YU38795 A YU 38795A YU 38795 A YU38795 A YU 38795A YU 38795 A YU38795 A YU 38795A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- releasing factor
- pct
- obtaining
- methods
- pharmaceutical compositions
- Prior art date
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
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- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
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- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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Abstract
Kortikotropinsko-otpuštajući faktor (CRF) antagonisti imaju formulu gde su grupe A, B, Y, Z, G, R3, R4, R5, R6, R16 i nije R17 definisani u procesu za njihovo dobijanje. Ova jedinjenja i njihove farmaceutski prihvatljive soli su veoma korisna kod tretmana CNS i stresnih uzrokovanih bolesti.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25551494A | 1994-06-08 | 1994-06-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
YU38795A true YU38795A (sh) | 1999-03-04 |
Family
ID=22968678
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU38795A YU38795A (sh) | 1994-06-08 | 1995-06-07 | Kortikotropinski otpuštajući faktor antagonisti, postupci za njihovo dobijanje i njihove farmaceutske smese |
Country Status (33)
Country | Link |
---|---|
US (1) | US5962479A (sh) |
EP (1) | EP0764166B1 (sh) |
JP (3) | JP3193055B2 (sh) |
KR (2) | KR100418240B1 (sh) |
CN (2) | CN1049659C (sh) |
AT (1) | ATE196295T1 (sh) |
AU (1) | AU692548B2 (sh) |
BR (1) | BR9502708A (sh) |
CA (1) | CA2192354C (sh) |
CO (1) | CO4440627A1 (sh) |
CZ (1) | CZ293752B6 (sh) |
DE (1) | DE69518841T2 (sh) |
DK (1) | DK0764166T3 (sh) |
ES (1) | ES2150567T3 (sh) |
FI (2) | FI114469B (sh) |
GR (1) | GR3034765T3 (sh) |
HK (1) | HK1026423A1 (sh) |
HR (1) | HRP950321B1 (sh) |
HU (1) | HUT75774A (sh) |
IL (1) | IL114004A0 (sh) |
MY (1) | MY114522A (sh) |
NO (2) | NO308994B1 (sh) |
NZ (1) | NZ285442A (sh) |
PE (1) | PE32596A1 (sh) |
PL (1) | PL320631A1 (sh) |
PT (1) | PT764166E (sh) |
RU (1) | RU2221799C2 (sh) |
SK (1) | SK155596A3 (sh) |
TW (2) | TW574214B (sh) |
UA (1) | UA71535C2 (sh) |
WO (1) | WO1995033750A1 (sh) |
YU (1) | YU38795A (sh) |
ZA (1) | ZA954677B (sh) |
Families Citing this family (186)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5854232A (en) * | 1994-04-29 | 1998-12-29 | Pfizer Inc. | Acyclic anc cyclic amides as neurotransmitter release enhancers |
EP0729758A3 (en) * | 1995-03-02 | 1997-10-29 | Pfizer | Pyrazolopyrimidines and pyrrolopyrimidines to treat neuronal disorders and other diseases |
US6956047B1 (en) | 1995-06-06 | 2005-10-18 | Pfizer Inc. | Corticotropin releasing factor antagonists |
US6403599B1 (en) * | 1995-11-08 | 2002-06-11 | Pfizer Inc | Corticotropin releasing factor antagonists |
US7125880B1 (en) | 1995-06-06 | 2006-10-24 | Pfizer Inc. | Corticotropin releasing factor antagonists |
US5955613A (en) * | 1995-10-13 | 1999-09-21 | Neurogen Corporation | Certain pyrrolopyridine derivatives; novel CRF1 specific ligands |
AU738304B2 (en) * | 1995-10-13 | 2001-09-13 | Neurogen Corporation | Certain pyrrolopyridine derivatives; novel CRF 1 specific ligands |
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