BR0208357A - Composto, composição farmacêutica, método de antagonização de um receptor de fator de liberação de corticotropina (crf), método de tratamento de disfunção, método de triagem de ligantes, método de detecção de receptores de crf, método de inibição da ligação de crf, artigo industrializado e usos do composto - Google Patents

Composto, composição farmacêutica, método de antagonização de um receptor de fator de liberação de corticotropina (crf), método de tratamento de disfunção, método de triagem de ligantes, método de detecção de receptores de crf, método de inibição da ligação de crf, artigo industrializado e usos do composto

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Publication number
BR0208357A
BR0208357A BR0208357-4A BR0208357A BR0208357A BR 0208357 A BR0208357 A BR 0208357A BR 0208357 A BR0208357 A BR 0208357A BR 0208357 A BR0208357 A BR 0208357A
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BR
Brazil
Prior art keywords
crf
receptor
corticotropin
compound
pharmaceutical composition
Prior art date
Application number
BR0208357-4A
Other languages
English (en)
Inventor
Paul J Gilligan
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Publication of BR0208357A publication Critical patent/BR0208357A/pt

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
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Abstract

"COMPOSTO, COMPOSIçãO FARMACêUTICA, MéTODO DE ANTAGONIZAçãO DE UM RECEPTOR DE FATOR DE LIBERAçãO DE CORTICOTROPINA (CRF), MéTODO DE TRATAMENTO DE DISFUNçãO, MéTODO DE TRIAGEM DE LIGANTES, MéTODO DE DETECçãO DE RECEPTORES DE CRF, MéTODO DE INIBIçãO DA LIGAçãO DE CRF, ARTIGO INDUSTRIALIZADO E USOS DO COMPOSTO". Antagonistas de fator de liberação de corticotropina (CRF) da Fórmula (I) e sua utilização no tratamento de ansiedade, depressão e outras disfunções psiquiátricas e neurológicas, bem como no tratamento de doenças imunológicas, cardiovasculares ou cardíacas e hipersensibilidade do cólon associada a distúrbios psicopatológicos e tensão.
BR0208357-4A 2001-03-13 2002-03-06 Composto, composição farmacêutica, método de antagonização de um receptor de fator de liberação de corticotropina (crf), método de tratamento de disfunção, método de triagem de ligantes, método de detecção de receptores de crf, método de inibição da ligação de crf, artigo industrializado e usos do composto BR0208357A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27540301P 2001-03-13 2001-03-13
PCT/US2002/006837 WO2002072202A1 (en) 2001-03-13 2002-03-06 4-(2-butylamino)-2,7-dimethyl-8-(2-methyl-6-methoxypyrid-3-yl) pyrazolo-[1,5-a]-1,3,5-triazine, its enantiomers and pharmaceutically acceptable salts as corticotropin releasing factor receptor ligands

Publications (1)

Publication Number Publication Date
BR0208357A true BR0208357A (pt) 2004-06-29

Family

ID=23052141

Family Applications (1)

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BR0208357-4A BR0208357A (pt) 2001-03-13 2002-03-06 Composto, composição farmacêutica, método de antagonização de um receptor de fator de liberação de corticotropina (crf), método de tratamento de disfunção, método de triagem de ligantes, método de detecção de receptores de crf, método de inibição da ligação de crf, artigo industrializado e usos do composto

Country Status (36)

Country Link
US (4) US20030125330A1 (pt)
EP (1) EP1368094B1 (pt)
JP (1) JP4549630B2 (pt)
KR (1) KR100875595B1 (pt)
CN (1) CN100427093C (pt)
AR (1) AR032986A1 (pt)
AT (1) ATE355102T1 (pt)
AU (1) AU2002245605B2 (pt)
BG (1) BG66331B1 (pt)
BR (1) BR0208357A (pt)
CA (1) CA2440553C (pt)
CY (1) CY1106607T1 (pt)
CZ (1) CZ20032481A3 (pt)
DE (1) DE60218434T2 (pt)
DK (1) DK1368094T3 (pt)
EE (1) EE05433B1 (pt)
ES (1) ES2282401T3 (pt)
GE (1) GEP20053608B (pt)
HK (1) HK1057182A1 (pt)
HR (1) HRP20030822B1 (pt)
HU (1) HU229317B1 (pt)
IL (2) IL157615A0 (pt)
IS (1) IS2839B (pt)
MX (1) MXPA03008185A (pt)
MY (1) MY146935A (pt)
NO (1) NO328580B1 (pt)
NZ (1) NZ528207A (pt)
PL (1) PL208278B1 (pt)
PT (1) PT1368094E (pt)
RS (1) RS50863B (pt)
RU (1) RU2292347C2 (pt)
SK (1) SK287603B6 (pt)
TW (1) TWI257388B (pt)
UA (1) UA74634C2 (pt)
WO (1) WO2002072202A1 (pt)
ZA (1) ZA200306995B (pt)

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