DK0772595T3 - Monomerisk og dimerisk naphthylisoquinolinalkaloider og syntesemetoder deraf - Google Patents

Monomerisk og dimerisk naphthylisoquinolinalkaloider og syntesemetoder deraf

Info

Publication number
DK0772595T3
DK0772595T3 DK95928091T DK95928091T DK0772595T3 DK 0772595 T3 DK0772595 T3 DK 0772595T3 DK 95928091 T DK95928091 T DK 95928091T DK 95928091 T DK95928091 T DK 95928091T DK 0772595 T3 DK0772595 T3 DK 0772595T3
Authority
DK
Denmark
Prior art keywords
monomeric
alkaloids
naphthylisoquinoline alkaloids
naphthylisoquinoline
present
Prior art date
Application number
DK95928091T
Other languages
English (en)
Inventor
Gerhard Bringmann
Sven Harmsen
Roland Gotz
Michael R Boyd
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/279,291 external-priority patent/US5552550A/en
Priority claimed from US08/279,339 external-priority patent/US5571919A/en
Application filed by Us Health filed Critical Us Health
Application granted granted Critical
Publication of DK0772595T3 publication Critical patent/DK0772595T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK95928091T 1994-07-22 1995-07-19 Monomerisk og dimerisk naphthylisoquinolinalkaloider og syntesemetoder deraf DK0772595T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/279,291 US5552550A (en) 1994-07-22 1994-07-22 Monomeric Naphthylisoquinoline alkaloids and synthesis methods thereof
US08/279,339 US5571919A (en) 1994-07-22 1994-07-22 Dimeric naphthylisoquinoline alkaloids and synthesis methods thereof
PCT/US1995/009132 WO1996003382A1 (en) 1994-07-22 1995-07-19 Monomeric and dimeric naphthylisoquinoline alkaloids and synthesis methods thereof

Publications (1)

Publication Number Publication Date
DK0772595T3 true DK0772595T3 (da) 2003-07-21

Family

ID=26959570

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95928091T DK0772595T3 (da) 1994-07-22 1995-07-19 Monomerisk og dimerisk naphthylisoquinolinalkaloider og syntesemetoder deraf

Country Status (10)

Country Link
EP (2) EP1325915A1 (da)
JP (1) JPH10506616A (da)
AT (1) ATE236127T1 (da)
AU (1) AU709428B2 (da)
CA (1) CA2195647A1 (da)
DE (1) DE69530209T2 (da)
DK (1) DK0772595T3 (da)
ES (1) ES2197205T3 (da)
PT (1) PT772595E (da)
WO (1) WO1996003382A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140339A (en) 1994-02-14 2000-10-31 The United States Of America As Represented By The Department Of Health And Human Services Monomeric and dimeric arylisoquinoline alkaloids and derivatives thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2100066C (en) * 1991-04-12 1996-08-13 Michael R. Boyd Michellamines useful as antiviral agents, composition and method of treatment
DE4117080A1 (de) * 1991-05-25 1992-11-26 Basf Ag Anwendung von dioncophyllinen als fungizide
WO1994024108A1 (en) * 1993-04-19 1994-10-27 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Michellamines useful as antiviral agents
US5639761A (en) * 1994-02-14 1997-06-17 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Antimalarial naphthylisoquinoline alkaloids and pharmaceutical compositions and medical uses thereof
US5409938A (en) * 1994-02-14 1995-04-25 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Antimalarial korupensamines and pharmaceutical compositions and medical uses thereof

Also Published As

Publication number Publication date
WO1996003382A1 (en) 1996-02-08
DE69530209T2 (de) 2004-03-04
EP1325915A1 (en) 2003-07-09
AU709428B2 (en) 1999-08-26
ES2197205T3 (es) 2004-01-01
JPH10506616A (ja) 1998-06-30
PT772595E (pt) 2003-08-29
DE69530209D1 (de) 2003-05-08
ATE236127T1 (de) 2003-04-15
CA2195647A1 (en) 1996-02-08
EP0772595B1 (en) 2003-04-02
EP0772595A1 (en) 1997-05-14
AU3196995A (en) 1996-02-22

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