YU33101A - Nove perle sa kontrolisanim oslobađanjem, postupak za njihovu proizvodnju i višestruka jedinična formulacija koja ih sadrži - Google Patents
Nove perle sa kontrolisanim oslobađanjem, postupak za njihovu proizvodnju i višestruka jedinična formulacija koja ih sadržiInfo
- Publication number
- YU33101A YU33101A YU33101A YU33101A YU33101A YU 33101 A YU33101 A YU 33101A YU 33101 A YU33101 A YU 33101A YU 33101 A YU33101 A YU 33101A YU 33101 A YU33101 A YU 33101A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- controlled release
- layer
- producing
- release bead
- same
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Perla sa kontrolisanim oslobadjanjem koju čini: (i) jedinično jezgro od inertnog materijala znatno rastvornog u vodi ili koji bubri u vodi; (ii) prvi sloj na jediničnom jezgru od polimera koji je znatno nerastvoran u vodi, (iii) drugi sloj koji pokriva prvi sloj i sadrži aktivnu materiju; i (iv) treći sloj polimera na drugom sloju efikasan u kontroli oslobadjanja aktivne supstance, gde je prvi sloj promenjen da kontroliše prodiranje vode u jezgro. Takodje je otkriven postupak za proizvodnju perli sa kontrolisanim oslobadjanjem.[A controlled release bead comprises: (i) a core unit of a substantially water-soluble or water-swellable inert material; (ii) a first layer on the core unit of a substantially water-insoluble polymer; (iii) a second layer covering the first layer and containing an active ingredient; and (iv) a third layer of polymer on the second layer effective for controlled release of the active ingredient, wherein the first layer is adapted to control water penetration into the core. A method of producing the controlled release bead is also disclosed.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9803871A SE9803871D0 (sv) | 1998-11-11 | 1998-11-11 | Therapeutic method and formulation |
PCT/SE1999/001463 WO2000012069A1 (en) | 1998-08-27 | 1999-08-26 | Therapeutic formulation for administering tolterodine with controlled release |
Publications (2)
Publication Number | Publication Date |
---|---|
YU33101A true YU33101A (sh) | 2003-10-31 |
RS49891B RS49891B (sr) | 2008-08-07 |
Family
ID=20413266
Country Status (40)
Country | Link |
---|---|
US (1) | US6911217B1 (sh) |
EP (1) | EP1128819B1 (sh) |
JP (1) | JP3616011B2 (sh) |
KR (1) | KR100467384B1 (sh) |
CN (1) | CN1169522C (sh) |
AP (1) | AP1323A (sh) |
AR (1) | AR027815A1 (sh) |
AT (1) | ATE247458T1 (sh) |
AU (1) | AU762410B2 (sh) |
BG (1) | BG65149B1 (sh) |
BR (1) | BRPI9915142B8 (sh) |
CA (1) | CA2350061C (sh) |
CZ (1) | CZ299582B6 (sh) |
DE (1) | DE69910604T2 (sh) |
DK (1) | DK1128819T3 (sh) |
EA (1) | EA005074B1 (sh) |
EE (1) | EE05232B1 (sh) |
ES (1) | ES2204193T3 (sh) |
GE (1) | GEP20022833B (sh) |
HK (1) | HK1040917B (sh) |
HR (1) | HRP20010333B1 (sh) |
HU (1) | HU226582B1 (sh) |
ID (1) | ID30039A (sh) |
IL (1) | IL142809A0 (sh) |
IS (1) | IS2370B (sh) |
MA (1) | MA25325A1 (sh) |
MY (1) | MY122195A (sh) |
NO (1) | NO331399B1 (sh) |
NZ (1) | NZ511430A (sh) |
OA (1) | OA11673A (sh) |
PL (1) | PL195780B1 (sh) |
PT (1) | PT1128819E (sh) |
RS (1) | RS49891B (sh) |
SE (1) | SE9803871D0 (sh) |
SI (1) | SI1128819T1 (sh) |
SK (1) | SK284758B6 (sh) |
TW (2) | TWI222879B (sh) |
UA (1) | UA57165C2 (sh) |
WO (1) | WO2000027364A1 (sh) |
ZA (1) | ZA200103575B (sh) |
Families Citing this family (78)
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AU728395B2 (en) * | 1996-07-19 | 2001-01-11 | Gunnar Aberg | S(-)-tolterodine in the treatment of urinary and gastrointestinal disorders |
US8563522B2 (en) | 1997-07-08 | 2013-10-22 | The Iams Company | Method of maintaining and/or attenuating a decline in quality of life |
EP0957073A1 (en) | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | Novel derivatives of 3,3-diphenylpropylamines |
EE05191B1 (et) * | 1999-11-11 | 2009-08-17 | Pharmacia Ab | Farmatseutiline kompositsioon, mis sisaldab tolterodiini, ja selle kasutamine |
EP1536780A1 (en) * | 2002-08-28 | 2005-06-08 | Pharmacia Corporation | Oral liquid tolterodine composition |
US8168170B2 (en) | 2002-10-03 | 2012-05-01 | The Procter And Gamble Company | Compositions having an inner core and at least three surrounding layers |
AU2004206110A1 (en) * | 2003-01-22 | 2004-08-05 | Pfizer Health Ab | Reduced dose of tolterodine and other antimuscarinic agents for treating urinary disorders |
DE10315917A1 (de) * | 2003-04-08 | 2004-11-18 | Schwarz Pharma Ag | Hochreine Basen von 3,3-Diphenylpropylaminmonoestern |
CA2529984C (en) | 2003-06-26 | 2012-09-25 | Isa Odidi | Oral multi-functional pharmaceutical capsule preparations of proton pump inhibitors |
CA2537103C (en) | 2003-11-04 | 2010-01-19 | Shire Laboratories, Inc. | Once daily dosage forms of trospium |
AU2004289222B2 (en) | 2003-11-04 | 2010-01-21 | Supernus Pharmaceuticals Inc. | Compositions of quaternary ammonium containing bioavailability enhancers |
US20050152884A1 (en) | 2003-12-19 | 2005-07-14 | The Procter & Gamble Company | Canine probiotic Bifidobacteria globosum |
US7785635B1 (en) | 2003-12-19 | 2010-08-31 | The Procter & Gamble Company | Methods of use of probiotic lactobacilli for companion animals |
US8894991B2 (en) | 2003-12-19 | 2014-11-25 | The Iams Company | Canine probiotic Lactobacilli |
US8877178B2 (en) | 2003-12-19 | 2014-11-04 | The Iams Company | Methods of use of probiotic bifidobacteria for companion animals |
US20050158294A1 (en) | 2003-12-19 | 2005-07-21 | The Procter & Gamble Company | Canine probiotic Bifidobacteria pseudolongum |
US8394409B2 (en) * | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
EP1629834A1 (en) | 2004-08-27 | 2006-03-01 | KRKA, D.D., Novo Mesto | Sustained release pharmaceutical composition of tolterodine |
EP1836156A1 (en) * | 2005-01-10 | 2007-09-26 | Teva Gyogyszergyar Reszvenytarsasag | Substantially pure tolterodine tartrate and process for preparing thereof |
EP2261323A1 (en) | 2005-05-31 | 2010-12-15 | The Iams Company | Feline probiotic lactobacilli |
PL1885383T3 (pl) | 2005-05-31 | 2017-06-30 | Iams Europe B.V. | Kocie probiotyczne bifidobakterie |
US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
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US8426391B2 (en) | 2006-02-03 | 2013-04-23 | Proventiv Therapeutics, Llc | Treating vitamin D insufficiency and deficiency with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 |
KR100714058B1 (ko) * | 2006-02-06 | 2007-05-02 | 한국유나이티드제약 주식회사 | 톨테로딘 엘-주석산염의 서방형 경구투여 조성물 및 이의 제조 방법 |
MX2008010877A (es) * | 2006-02-24 | 2008-11-25 | Teva Pharma | Tabletas de liberacion prolongada de succinato de metroprolol y metodos para su preparacion. |
BRPI0708848A2 (pt) * | 2006-03-21 | 2011-06-21 | Teva Pharma | formulação de liberação controlada de tolterodina |
EP1839649A1 (en) * | 2006-03-31 | 2007-10-03 | LEK Pharmaceuticals D.D. | Coated formulations for tolterodine |
US9561188B2 (en) * | 2006-04-03 | 2017-02-07 | Intellipharmaceutics Corporation | Controlled release delivery device comprising an organosol coat |
EP2015735A1 (en) * | 2006-04-21 | 2009-01-21 | Synthon B.V. | Tolterodine beads |
US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
EP2026766A1 (en) | 2006-05-17 | 2009-02-25 | Synthon B.V. | Tablet composition with a prolonged release of tamsulosin |
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JP2008007458A (ja) * | 2006-06-29 | 2008-01-17 | Freunt Ind Co Ltd | レイヤリング用核粒子とその製造方法 |
EA018036B1 (ru) | 2006-11-27 | 2013-05-30 | Х. Лундбекк А/С | Гетероариламидные производные |
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WO2011061616A2 (en) | 2009-11-23 | 2011-05-26 | Micro Labs Limited | Extended release compositions containing tolterodine and process for preparing the same |
WO2011095388A1 (en) | 2010-02-04 | 2011-08-11 | Synthon Bv | Tolterodine bead |
JO3112B1 (ar) | 2010-03-29 | 2017-09-20 | Ferring Bv | تركيبة دوائية سريعة التحلل |
EP3636280A1 (en) | 2010-03-29 | 2020-04-15 | Opko Ireland Global Holdings, Ltd. | Methods and compositions for reducing parathyroid levels |
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SG10201911274TA (en) | 2014-08-07 | 2020-02-27 | Opko Ireland Global Holdings Ltd | Adjunctive therapy with 25-hydroxyvitamin d |
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-
1998
- 1998-11-11 SE SE9803871A patent/SE9803871D0/xx unknown
-
1999
- 1999-11-11 SK SK625-2001A patent/SK284758B6/sk not_active IP Right Cessation
- 1999-11-11 CA CA002350061A patent/CA2350061C/en not_active Expired - Lifetime
- 1999-11-11 AP APAP/P/2001/002166A patent/AP1323A/en active
- 1999-11-11 CZ CZ20011627A patent/CZ299582B6/cs not_active IP Right Cessation
- 1999-11-11 EE EEP200100254A patent/EE05232B1/xx unknown
- 1999-11-11 PT PT99971702T patent/PT1128819E/pt unknown
- 1999-11-11 AT AT99971702T patent/ATE247458T1/de active
- 1999-11-11 JP JP2000580595A patent/JP3616011B2/ja not_active Expired - Lifetime
- 1999-11-11 CN CNB998132160A patent/CN1169522C/zh not_active Expired - Lifetime
- 1999-11-11 PL PL99348612A patent/PL195780B1/pl unknown
- 1999-11-11 NZ NZ511430A patent/NZ511430A/en not_active IP Right Cessation
- 1999-11-11 OA OA1200100112A patent/OA11673A/en unknown
- 1999-11-11 EA EA200100538A patent/EA005074B1/ru not_active IP Right Cessation
- 1999-11-11 DK DK99971702T patent/DK1128819T3/da active
- 1999-11-11 AU AU14366/00A patent/AU762410B2/en not_active Expired
- 1999-11-11 ES ES99971702T patent/ES2204193T3/es not_active Expired - Lifetime
- 1999-11-11 HU HU0105038A patent/HU226582B1/hu unknown
- 1999-11-11 UA UA2001042824A patent/UA57165C2/uk unknown
- 1999-11-11 MY MYPI99004911A patent/MY122195A/en unknown
- 1999-11-11 KR KR10-2001-7005879A patent/KR100467384B1/ko active IP Right Grant
- 1999-11-11 EP EP99971702A patent/EP1128819B1/en not_active Expired - Lifetime
- 1999-11-11 US US09/763,281 patent/US6911217B1/en not_active Expired - Lifetime
- 1999-11-11 AR ARP990105734A patent/AR027815A1/es active IP Right Grant
- 1999-11-11 SI SI9930411T patent/SI1128819T1/xx unknown
- 1999-11-11 ID IDW00200101038A patent/ID30039A/id unknown
- 1999-11-11 IL IL14280999A patent/IL142809A0/xx unknown
- 1999-11-11 RS YUP-331/01A patent/RS49891B/sr unknown
- 1999-11-11 WO PCT/SE1999/002052 patent/WO2000027364A1/en active IP Right Grant
- 1999-11-11 DE DE69910604T patent/DE69910604T2/de not_active Expired - Lifetime
- 1999-11-11 GE GEAP19995939A patent/GEP20022833B/en unknown
- 1999-11-11 BR BRPI9915142A patent/BRPI9915142B8/pt not_active IP Right Cessation
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2000
- 2000-02-11 TW TW089102338A patent/TWI222879B/zh not_active IP Right Cessation
- 2000-02-11 TW TW089102332A patent/TWI267385B/zh not_active IP Right Cessation
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2001
- 2001-05-03 ZA ZA200103575A patent/ZA200103575B/en unknown
- 2001-05-09 IS IS5936A patent/IS2370B/is unknown
- 2001-05-10 NO NO20012314A patent/NO331399B1/no not_active IP Right Cessation
- 2001-05-10 HR HR20010333A patent/HRP20010333B1/xx not_active IP Right Cessation
- 2001-06-08 MA MA26228A patent/MA25325A1/fr unknown
- 2001-06-08 BG BG105582A patent/BG65149B1/bg unknown
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2002
- 2002-04-04 HK HK02102521.2A patent/HK1040917B/zh not_active IP Right Cessation
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