YU33101A - Nove perle sa kontrolisanim oslobađanjem, postupak za njihovu proizvodnju i višestruka jedinična formulacija koja ih sadrži - Google Patents

Nove perle sa kontrolisanim oslobađanjem, postupak za njihovu proizvodnju i višestruka jedinična formulacija koja ih sadrži

Info

Publication number
YU33101A
YU33101A YU33101A YU33101A YU33101A YU 33101 A YU33101 A YU 33101A YU 33101 A YU33101 A YU 33101A YU 33101 A YU33101 A YU 33101A YU 33101 A YU33101 A YU 33101A
Authority
YU
Yugoslavia
Prior art keywords
controlled release
layer
producing
release bead
same
Prior art date
Application number
YU33101A
Other languages
English (en)
Inventor
Torkel Gren
Anders Ringberg
Martin Wikberg
Randy J. Wald
Original Assignee
Pharmacia Ab.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20413266&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU33101(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/SE1999/001463 external-priority patent/WO2000012069A1/en
Application filed by Pharmacia Ab. filed Critical Pharmacia Ab.
Publication of YU33101A publication Critical patent/YU33101A/sh
Publication of RS49891B publication Critical patent/RS49891B/sr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Perla sa kontrolisanim oslobadjanjem koju čini: (i) jedinično jezgro od inertnog materijala znatno rastvornog u vodi ili koji bubri u vodi; (ii) prvi sloj na jediničnom jezgru od polimera koji je znatno nerastvoran u vodi, (iii) drugi sloj koji pokriva prvi sloj i sadrži aktivnu materiju; i (iv) treći sloj polimera na drugom sloju efikasan u kontroli oslobadjanja aktivne supstance, gde je prvi sloj promenjen da kontroliše prodiranje vode u jezgro. Takodje je otkriven postupak za proizvodnju perli sa kontrolisanim oslobadjanjem.[A controlled release bead comprises: (i) a core unit of a substantially water-soluble or water-swellable inert material; (ii) a first layer on the core unit of a substantially water-insoluble polymer; (iii) a second layer covering the first layer and containing an active ingredient; and (iv) a third layer of polymer on the second layer effective for controlled release of the active ingredient, wherein the first layer is adapted to control water penetration into the core. A method of producing the controlled release bead is also disclosed.
YUP-331/01A 1998-11-11 1999-11-11 Nove perle sa kontrolisanim oslobadjanjem, postupak za njihovu proizvodnju i višestruka jedinična formulacija koja ih sadrži RS49891B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9803871A SE9803871D0 (sv) 1998-11-11 1998-11-11 Therapeutic method and formulation
PCT/SE1999/001463 WO2000012069A1 (en) 1998-08-27 1999-08-26 Therapeutic formulation for administering tolterodine with controlled release

Publications (2)

Publication Number Publication Date
YU33101A true YU33101A (sh) 2003-10-31
RS49891B RS49891B (sr) 2008-08-07

Family

ID=20413266

Country Status (40)

Country Link
US (1) US6911217B1 (sh)
EP (1) EP1128819B1 (sh)
JP (1) JP3616011B2 (sh)
KR (1) KR100467384B1 (sh)
CN (1) CN1169522C (sh)
AP (1) AP1323A (sh)
AR (1) AR027815A1 (sh)
AT (1) ATE247458T1 (sh)
AU (1) AU762410B2 (sh)
BG (1) BG65149B1 (sh)
BR (1) BRPI9915142B8 (sh)
CA (1) CA2350061C (sh)
CZ (1) CZ299582B6 (sh)
DE (1) DE69910604T2 (sh)
DK (1) DK1128819T3 (sh)
EA (1) EA005074B1 (sh)
EE (1) EE05232B1 (sh)
ES (1) ES2204193T3 (sh)
GE (1) GEP20022833B (sh)
HK (1) HK1040917B (sh)
HR (1) HRP20010333B1 (sh)
HU (1) HU226582B1 (sh)
ID (1) ID30039A (sh)
IL (1) IL142809A0 (sh)
IS (1) IS2370B (sh)
MA (1) MA25325A1 (sh)
MY (1) MY122195A (sh)
NO (1) NO331399B1 (sh)
NZ (1) NZ511430A (sh)
OA (1) OA11673A (sh)
PL (1) PL195780B1 (sh)
PT (1) PT1128819E (sh)
RS (1) RS49891B (sh)
SE (1) SE9803871D0 (sh)
SI (1) SI1128819T1 (sh)
SK (1) SK284758B6 (sh)
TW (2) TWI222879B (sh)
UA (1) UA57165C2 (sh)
WO (1) WO2000027364A1 (sh)
ZA (1) ZA200103575B (sh)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU728395B2 (en) * 1996-07-19 2001-01-11 Gunnar Aberg S(-)-tolterodine in the treatment of urinary and gastrointestinal disorders
US8563522B2 (en) 1997-07-08 2013-10-22 The Iams Company Method of maintaining and/or attenuating a decline in quality of life
EP0957073A1 (en) 1998-05-12 1999-11-17 Schwarz Pharma Ag Novel derivatives of 3,3-diphenylpropylamines
EE05191B1 (et) * 1999-11-11 2009-08-17 Pharmacia Ab Farmatseutiline kompositsioon, mis sisaldab tolterodiini, ja selle kasutamine
EP1536780A1 (en) * 2002-08-28 2005-06-08 Pharmacia Corporation Oral liquid tolterodine composition
US8168170B2 (en) 2002-10-03 2012-05-01 The Procter And Gamble Company Compositions having an inner core and at least three surrounding layers
AU2004206110A1 (en) * 2003-01-22 2004-08-05 Pfizer Health Ab Reduced dose of tolterodine and other antimuscarinic agents for treating urinary disorders
DE10315917A1 (de) * 2003-04-08 2004-11-18 Schwarz Pharma Ag Hochreine Basen von 3,3-Diphenylpropylaminmonoestern
CA2529984C (en) 2003-06-26 2012-09-25 Isa Odidi Oral multi-functional pharmaceutical capsule preparations of proton pump inhibitors
CA2537103C (en) 2003-11-04 2010-01-19 Shire Laboratories, Inc. Once daily dosage forms of trospium
AU2004289222B2 (en) 2003-11-04 2010-01-21 Supernus Pharmaceuticals Inc. Compositions of quaternary ammonium containing bioavailability enhancers
US20050152884A1 (en) 2003-12-19 2005-07-14 The Procter & Gamble Company Canine probiotic Bifidobacteria globosum
US7785635B1 (en) 2003-12-19 2010-08-31 The Procter & Gamble Company Methods of use of probiotic lactobacilli for companion animals
US8894991B2 (en) 2003-12-19 2014-11-25 The Iams Company Canine probiotic Lactobacilli
US8877178B2 (en) 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
US20050158294A1 (en) 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
EP1629834A1 (en) 2004-08-27 2006-03-01 KRKA, D.D., Novo Mesto Sustained release pharmaceutical composition of tolterodine
EP1836156A1 (en) * 2005-01-10 2007-09-26 Teva Gyogyszergyar Reszvenytarsasag Substantially pure tolterodine tartrate and process for preparing thereof
EP2261323A1 (en) 2005-05-31 2010-12-15 The Iams Company Feline probiotic lactobacilli
PL1885383T3 (pl) 2005-05-31 2017-06-30 Iams Europe B.V. Kocie probiotyczne bifidobakterie
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
EP2997953B1 (en) 2006-01-18 2018-12-26 Intec Pharma Ltd. Delivery device for oral intake of an agent
US8426391B2 (en) 2006-02-03 2013-04-23 Proventiv Therapeutics, Llc Treating vitamin D insufficiency and deficiency with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3
KR100714058B1 (ko) * 2006-02-06 2007-05-02 한국유나이티드제약 주식회사 톨테로딘 엘-주석산염의 서방형 경구투여 조성물 및 이의 제조 방법
MX2008010877A (es) * 2006-02-24 2008-11-25 Teva Pharma Tabletas de liberacion prolongada de succinato de metroprolol y metodos para su preparacion.
BRPI0708848A2 (pt) * 2006-03-21 2011-06-21 Teva Pharma formulação de liberação controlada de tolterodina
EP1839649A1 (en) * 2006-03-31 2007-10-03 LEK Pharmaceuticals D.D. Coated formulations for tolterodine
US9561188B2 (en) * 2006-04-03 2017-02-07 Intellipharmaceutics Corporation Controlled release delivery device comprising an organosol coat
EP2015735A1 (en) * 2006-04-21 2009-01-21 Synthon B.V. Tolterodine beads
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
EP2026766A1 (en) 2006-05-17 2009-02-25 Synthon B.V. Tablet composition with a prolonged release of tamsulosin
SI2679228T1 (en) 2006-06-21 2018-06-29 Opko Ireland Global Holdings, Ltd. THERAPY WITH THE USE OF VITAMIN D ADDITIONAL FIBER AND HORMON RESISTANCE OF VITAMIN D
JP2008007458A (ja) * 2006-06-29 2008-01-17 Freunt Ind Co Ltd レイヤリング用核粒子とその製造方法
EA018036B1 (ru) 2006-11-27 2013-05-30 Х. Лундбекк А/С Гетероариламидные производные
WO2008093303A2 (en) 2007-02-01 2008-08-07 The Iams Company Method for decreasing inflammation and stress in a mammal using glucose antimetaboltes, avocado or avocado extracts
DK3342405T3 (da) 2007-04-25 2019-11-11 Opko Ireland Global Holdings Ltd Kontrolleret frigivelse af 25-hydroxyvitamin d
WO2008134523A1 (en) 2007-04-25 2008-11-06 Proventiv Therapeutics, Llc Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease
ES2403107T3 (es) 2007-04-25 2013-05-14 Cytochroma Inc. Método de tratamiento de insuficiencia y deficiencia de vitamina D
CL2008001970A1 (es) * 2007-07-03 2009-03-27 Synthon Bv Perla con un nucleo de celulosa microcristalina, un recubrimiento soluble en agua con un polimero vinil pirrolidina, una capa con tolterodina y un aglutinante, y una capa de liberacion controlada con un poliacrilato; proceso para prepararla; forma de dosificacion, util en trastornos urinarios como vejiga hiperactiva.
US8110226B2 (en) * 2007-07-20 2012-02-07 Mylan Pharmaceuticals Inc. Drug formulations having inert sealed cores
US8486452B2 (en) * 2007-07-20 2013-07-16 Mylan Pharmaceuticals Inc. Stabilized tolterodine tartrate formulations
US8871275B2 (en) 2007-08-08 2014-10-28 Inventia Healthcare Private Limited Extended release compositions comprising tolterodine
CN101801350A (zh) * 2007-08-13 2010-08-11 阿巴斯迪特宁医药有限公司 抗滥用药物、使用方法和制备方法
US20090192228A1 (en) * 2008-01-28 2009-07-30 Actavis Group Ptc Ehf Controlled-Release Tolterodine Compositions and Methods
US20090214665A1 (en) * 2008-02-26 2009-08-27 Lai Felix S Controlled Release Muscarinic Receptor Antagonist Formulation
CA2629099A1 (en) * 2008-04-01 2009-10-01 Pharmascience Inc. Novel oral controlled release pharmaceutical formulations
KR101852042B1 (ko) 2008-04-02 2018-04-25 사이토크로마 인코포레이티드 비타민 d 결핍 및 관련 장애에 유용한 방법, 조성물, 용도 및 키트
US20090311317A1 (en) * 2008-05-14 2009-12-17 Capricorn Pharma Inc. Modified release tolterodine formulations
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
US8465770B2 (en) 2008-12-24 2013-06-18 Synthon Bv Low dose controlled release tablet
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
AU2010277207B2 (en) * 2009-07-31 2014-06-26 Sun Pharmaceutical Industries Limited Multi-layered, multiple unit pharmaceutical compositions
WO2011061616A2 (en) 2009-11-23 2011-05-26 Micro Labs Limited Extended release compositions containing tolterodine and process for preparing the same
WO2011095388A1 (en) 2010-02-04 2011-08-11 Synthon Bv Tolterodine bead
JO3112B1 (ar) 2010-03-29 2017-09-20 Ferring Bv تركيبة دوائية سريعة التحلل
EP3636280A1 (en) 2010-03-29 2020-04-15 Opko Ireland Global Holdings, Ltd. Methods and compositions for reducing parathyroid levels
CA2793485A1 (en) 2010-03-29 2011-10-06 Ferring B.V. A fast dissolving pharmaceutical composition
US8748433B2 (en) 2010-04-30 2014-06-10 Merck Sharp & Dohme Corp. β3 adrenergic receptor agonists
US20120040008A1 (en) * 2010-08-11 2012-02-16 Ashish Chatterji Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
WO2012154770A1 (en) 2011-05-10 2012-11-15 Theravida, Inc. Combinations of tolterodine and salivary stimulants for the treatment of overactive bladder
GR1007628B (el) 2011-07-27 2012-06-29 Φαρματεν Αβεε, Φαρμακευτικο σκευασμα περιεχον εναν αντιμουσκαρινικο παραγοντα και μεθοδος για την παρασκευη αυτου
WO2013037708A1 (en) 2011-09-16 2013-03-21 Ferring B.V. A fast dissolving pharmaceutical composition
US20140242158A1 (en) * 2011-09-30 2014-08-28 Astellas Pharma, Inc. Granular Pharmaceutical Composition
MX2015000541A (es) 2012-07-12 2015-05-11 Ferring Bv Formulaciones de diclofenaco.
JP2015529255A (ja) * 2012-09-20 2015-10-05 オーエイチアール ファーマ, エルエルシーOhr Pharma, Llc 治療薬の持続放出のための多層の生体分解可能なマイクロ粒子
TW201422254A (zh) * 2012-11-21 2014-06-16 Ferring Bv 用於速釋及延釋的組成物
US20150306170A1 (en) * 2012-11-21 2015-10-29 Ferring B.V. Composition for immediate and extended release
EP2968579B1 (en) * 2013-03-13 2020-04-15 Intervet International B.V. Stable bioactive substances and methods of making
CA2907428A1 (en) 2013-03-15 2014-09-18 Inspirion Delivery Technologies, Llc Abuse deterrent compositions and methods of use
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 d 방출 제형
AU2014246617A1 (en) 2013-12-23 2015-07-09 Sun Pharmaceutical Industries Limited Multi-layered, multiple unit pharmaceutical compositions
SG10201911274TA (en) 2014-08-07 2020-02-27 Opko Ireland Global Holdings Ltd Adjunctive therapy with 25-hydroxyvitamin d
US10729685B2 (en) 2014-09-15 2020-08-04 Ohemo Life Sciences Inc. Orally administrable compositions and methods of deterring abuse by intranasal administration
CA2936748C (en) * 2014-10-31 2017-08-08 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
WO2017146053A1 (ja) * 2016-02-23 2017-08-31 ニプロ株式会社 医薬組成物粒子とそれを含む口腔内崩壊製剤
SG10201913863TA (en) 2016-03-28 2020-03-30 Opko Ireland Global Holdings Limited Methods of vitamin d treatment

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1144911B (it) * 1981-03-19 1986-10-29 Pharmatec Spa Composizione farmaceutica a rilascio controllato contenente ibuprofen
JPH07107450A (ja) 1993-10-08 1995-04-21 Hitachi Ltd 情報通信装置
JP3453186B2 (ja) 1994-04-14 2003-10-06 共和薬品工業株式会社 徐放性マイクロカプセルおよびその製造方法
SE9402422D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New beads for controlled release and a pharmaceutical preparation containing the same
US5645858A (en) * 1994-10-06 1997-07-08 Ortho Pharmaceutical Corporation Multilayered controlled release pharmaceutical dosage form
US5567441A (en) 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
AU728395B2 (en) 1996-07-19 2001-01-11 Gunnar Aberg S(-)-tolterodine in the treatment of urinary and gastrointestinal disorders
US6312728B1 (en) * 1998-07-07 2001-11-06 Cascade Development, Inc. Sustained release pharmaceutical preparation

Also Published As

Publication number Publication date
HK1040917A1 (en) 2002-06-28
IS5936A (is) 2001-05-09
ZA200103575B (en) 2002-05-03
ATE247458T1 (de) 2003-09-15
DK1128819T3 (da) 2003-12-01
MY122195A (en) 2006-03-31
HRP20010333B1 (en) 2004-10-31
TWI267385B (en) 2006-12-01
NZ511430A (en) 2003-05-30
SI1128819T1 (en) 2003-12-31
SK284758B6 (sk) 2005-11-03
MA25325A1 (fr) 2001-12-31
PL195780B1 (pl) 2007-10-31
BRPI9915142B8 (pt) 2021-05-25
BRPI9915142B1 (pt) 2015-08-25
BG105582A (en) 2001-12-29
HU226582B1 (en) 2009-04-28
UA57165C2 (uk) 2003-06-16
CZ299582B6 (cs) 2008-09-10
NO20012314D0 (no) 2001-05-10
JP2003517446A (ja) 2003-05-27
AU762410B2 (en) 2003-06-26
HK1040917B (zh) 2005-05-27
CA2350061A1 (en) 2000-05-18
SE9803871D0 (sv) 1998-11-11
NO331399B1 (no) 2011-12-19
CZ20011627A3 (cs) 2001-10-17
CA2350061C (en) 2005-05-17
ID30039A (id) 2001-11-01
EE200100254A (et) 2002-12-16
US6911217B1 (en) 2005-06-28
AU1436600A (en) 2000-05-29
AR027815A1 (es) 2003-04-16
EA005074B1 (ru) 2004-10-28
NO20012314L (no) 2001-07-09
TWI222879B (en) 2004-11-01
EP1128819B1 (en) 2003-08-20
OA11673A (en) 2005-01-12
HRP20010333A2 (en) 2003-04-30
IL142809A0 (en) 2002-03-10
PL348612A1 (en) 2002-06-03
KR100467384B1 (ko) 2005-01-24
HUP0105038A2 (en) 2002-06-29
PT1128819E (pt) 2003-12-31
GEP20022833B (en) 2002-11-25
BR9915142A (pt) 2001-08-07
AP1323A (en) 2004-11-05
CN1326339A (zh) 2001-12-12
WO2000027364A1 (en) 2000-05-18
DE69910604T2 (de) 2004-06-24
CN1169522C (zh) 2004-10-06
HUP0105038A3 (en) 2006-07-28
AP2001002166A0 (en) 2001-06-30
KR20010075695A (ko) 2001-08-09
RS49891B (sr) 2008-08-07
EE05232B1 (et) 2009-12-15
EP1128819A1 (en) 2001-09-05
JP3616011B2 (ja) 2005-02-02
IS2370B (is) 2008-06-15
EA200100538A1 (ru) 2001-10-22
BG65149B1 (bg) 2007-04-30
DE69910604D1 (de) 2003-09-25
SK6252001A3 (en) 2002-01-07
ES2204193T3 (es) 2004-04-16

Similar Documents

Publication Publication Date Title
YU33101A (sh) Nove perle sa kontrolisanim oslobađanjem, postupak za njihovu proizvodnju i višestruka jedinična formulacija koja ih sadrži
MXPA02004574A (es) Formulacion farmaceutica que contiene tolterodina y su uso.
AU2684497A (en) Biodegradable sustained-release preparation, biodegradable pheromone dispenser and biodegradable pest controlling agent
PL397728A1 (pl) Zastosowanie kompozycji herbicydów, sposób zwalczania szkodliwych roślin i preparat chwastobójczy
AU6853698A (en) Method and device for exposure control, method and device for exposure, and method of manufacture of device
DE59507193D1 (de) VERFAHREN ZU hERSTELLUNG EINER MANTELTABLETTE MIT SPITZEM KERN
AU8109398A (en) Implants for controlled release of pharmaceutically active principles and method for making same
AU2499100A (en) Method and apparatus for selectively controlling the quantum state probability distribution of entangled quantum objects
AU2963400A (en) Improved controlled release compositions and method
AU698240B2 (en) Composition providing selective release of an active ingredient
AU7599100A (en) Control method and system for use when growing thin-films on semiconductor-basedmaterials
EP0741109A3 (en) Method and composition for enhancing biocidal activity
AU7569796A (en) Multivalent polymers, processes for their preparation, and their use for preparing biologically active compounds.
AU2001293077A1 (en) System and method for distributed multi-party call control
MX9603645A (es) Materiales antimicrobianos.
AU3090999A (en) Artificial surface active lure apparatus and method
AU3708100A (en) Method for protecting and/or controlled release of active ingredients
WO2002005200A8 (en) A method, an apparatus, and a composition for customizing the combination of fragrances
AU1534895A (en) Weed-suppressing agent, method for preparing it and its use in weed control
AU3828697A (en) Granulated formulation and method for stabilizing biocontrol agents
MY122558A (en) Solid crop protection formulation
CA2414753A1 (en) Dermal therapeutic system containing 2-(3-benzophenyl)-propionic acid or [0-(2,6-dichloranilino)-phenyl]-ethanoic acid
AU9693598A (en) Formulations and methods for insect control
AU1092095A (en) Intra-uterine ring for the release of an active agent, such as a hormone, and an introducer
CA2349114A1 (en) Insecticidal mat and heat-transpiration insecticidal method using the same