DE69910604D1 - Neue kügelchen mit kontrollierter freisetzung, ein verfahren zu deren herstellung und diese enthaltende formulierung des typs "multiple unit" - Google Patents

Neue kügelchen mit kontrollierter freisetzung, ein verfahren zu deren herstellung und diese enthaltende formulierung des typs "multiple unit"

Info

Publication number
DE69910604D1
DE69910604D1 DE69910604T DE69910604T DE69910604D1 DE 69910604 D1 DE69910604 D1 DE 69910604D1 DE 69910604 T DE69910604 T DE 69910604T DE 69910604 T DE69910604 T DE 69910604T DE 69910604 D1 DE69910604 D1 DE 69910604D1
Authority
DE
Germany
Prior art keywords
formulation
production
type
controlled release
multiple unit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69910604T
Other languages
English (en)
Other versions
DE69910604T2 (de
Inventor
Torkel Gren
Anders Ringberg
Martin Wikberg
J Wald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Pharmacia AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20413266&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69910604(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/SE1999/001463 external-priority patent/WO2000012069A1/en
Application filed by Pharmacia AB filed Critical Pharmacia AB
Publication of DE69910604D1 publication Critical patent/DE69910604D1/de
Application granted granted Critical
Publication of DE69910604T2 publication Critical patent/DE69910604T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69910604T 1998-11-11 1999-11-11 Neue kügelchen mit kontrollierter freisetzung, ein verfahren zu deren herstellung und diese enthaltende formulierung des typs "multiple unit" Expired - Lifetime DE69910604T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SE9803871A SE9803871D0 (sv) 1998-11-11 1998-11-11 Therapeutic method and formulation
SE9803871 1998-11-11
WOPCT/SE99/01463 1999-08-26
PCT/SE1999/001463 WO2000012069A1 (en) 1998-08-27 1999-08-26 Therapeutic formulation for administering tolterodine with controlled release
PCT/SE1999/002052 WO2000027364A1 (en) 1998-11-11 1999-11-11 New controlled release bead, a method of producing the same and multiple unit formulation comprising it

Publications (2)

Publication Number Publication Date
DE69910604D1 true DE69910604D1 (de) 2003-09-25
DE69910604T2 DE69910604T2 (de) 2004-06-24

Family

ID=20413266

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69910604T Expired - Lifetime DE69910604T2 (de) 1998-11-11 1999-11-11 Neue kügelchen mit kontrollierter freisetzung, ein verfahren zu deren herstellung und diese enthaltende formulierung des typs "multiple unit"

Country Status (40)

Country Link
US (1) US6911217B1 (de)
EP (1) EP1128819B1 (de)
JP (1) JP3616011B2 (de)
KR (1) KR100467384B1 (de)
CN (1) CN1169522C (de)
AP (1) AP1323A (de)
AR (1) AR027815A1 (de)
AT (1) ATE247458T1 (de)
AU (1) AU762410B2 (de)
BG (1) BG65149B1 (de)
BR (1) BRPI9915142B8 (de)
CA (1) CA2350061C (de)
CZ (1) CZ299582B6 (de)
DE (1) DE69910604T2 (de)
DK (1) DK1128819T3 (de)
EA (1) EA005074B1 (de)
EE (1) EE05232B1 (de)
ES (1) ES2204193T3 (de)
GE (1) GEP20022833B (de)
HK (1) HK1040917B (de)
HR (1) HRP20010333B1 (de)
HU (1) HU226582B1 (de)
ID (1) ID30039A (de)
IL (1) IL142809A0 (de)
IS (1) IS2370B (de)
MA (1) MA25325A1 (de)
MY (1) MY122195A (de)
NO (1) NO331399B1 (de)
NZ (1) NZ511430A (de)
OA (1) OA11673A (de)
PL (1) PL195780B1 (de)
PT (1) PT1128819E (de)
RS (1) RS49891B (de)
SE (1) SE9803871D0 (de)
SI (1) SI1128819T1 (de)
SK (1) SK284758B6 (de)
TW (2) TWI267385B (de)
UA (1) UA57165C2 (de)
WO (1) WO2000027364A1 (de)
ZA (1) ZA200103575B (de)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0924983A4 (de) * 1996-07-19 1999-08-25 Gunnar Aberg S(-)-tolterodin in der behandlung urinärer und gastrointestinaler störungen
US8563522B2 (en) 1997-07-08 2013-10-22 The Iams Company Method of maintaining and/or attenuating a decline in quality of life
EP0957073A1 (de) * 1998-05-12 1999-11-17 Schwarz Pharma Ag 3,3-Diphenylpropylaminderivate
AU784104B2 (en) * 1999-11-11 2006-02-02 Pfizer Health Ab Pharmaceutical formulation containing tolterodine and its use
MXPA05002302A (es) * 2002-08-28 2005-06-08 Pharmacia Corp Composicion liquida oral de tolterodina.
US8168170B2 (en) 2002-10-03 2012-05-01 The Procter And Gamble Company Compositions having an inner core and at least three surrounding layers
ATE432070T1 (de) * 2003-01-22 2009-06-15 Pfizer Health Ab Herabgesetzte dosis von tolterodin zur behandlung von harnwegserkrankungen
DE10315917A1 (de) * 2003-04-08 2004-11-18 Schwarz Pharma Ag Hochreine Basen von 3,3-Diphenylpropylaminmonoestern
CA2529984C (en) 2003-06-26 2012-09-25 Isa Odidi Oral multi-functional pharmaceutical capsule preparations of proton pump inhibitors
DE602004030931D1 (de) 2003-11-04 2011-02-17 Supernus Pharmaceuticals Inc
WO2005046663A1 (en) 2003-11-04 2005-05-26 Shire Laboratories, Inc. Compositions of quaternary ammonium containing bioavailability enhancers
US20050158294A1 (en) 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
US8877178B2 (en) 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
US8894991B2 (en) 2003-12-19 2014-11-25 The Iams Company Canine probiotic Lactobacilli
US20050152884A1 (en) 2003-12-19 2005-07-14 The Procter & Gamble Company Canine probiotic Bifidobacteria globosum
US7785635B1 (en) 2003-12-19 2010-08-31 The Procter & Gamble Company Methods of use of probiotic lactobacilli for companion animals
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
EP1629834A1 (de) 2004-08-27 2006-03-01 KRKA, D.D., Novo Mesto Pharmazeutische Zusammensetzung von Tolterodin mit verzögerter Freisetzung
US20060194876A1 (en) * 2005-01-10 2006-08-31 Kovacs Laszlo Z Substantially pure tolterodine tartrate and process for preparing thereof
WO2006130188A1 (en) 2005-05-31 2006-12-07 The Iams Company Feline probiotic bifidobacteria
EP2270131A1 (de) 2005-05-31 2011-01-05 The Iams Company Probiotische Katzen-Laktobazillen
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
ES2559678T3 (es) 2006-01-18 2016-02-15 Intec Pharma Ltd. Método para formar dispositivos de suministro para la vía oral de un agente
PL3095447T3 (pl) 2006-02-03 2022-02-14 Opko Renal, Llc Leczenie niedoboru lub deficytu witaminy d 25-hydroksywitaminą d2 i 25- hydroksywitaminą d3
KR100714058B1 (ko) * 2006-02-06 2007-05-02 한국유나이티드제약 주식회사 톨테로딘 엘-주석산염의 서방형 경구투여 조성물 및 이의 제조 방법
BRPI0621397A2 (pt) * 2006-02-24 2012-04-17 Teva Pharma tabletes de liberação prolongada de metoprolol succinato e seus processos de preparação
MX2008011952A (es) * 2006-03-21 2008-10-01 Teva Pharma Formulacion de liberacion controlad de tolterodina.
EP1839649A1 (de) * 2006-03-31 2007-10-03 LEK Pharmaceuticals D.D. Beschichtete Formulierung von Tolterodine
CN104825397A (zh) * 2006-04-03 2015-08-12 伊萨·奥迪迪 含有机溶胶涂层的受控释放递送物件
WO2007122015A1 (en) * 2006-04-21 2007-11-01 Synthon B.V. Tolterodine beads
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
EP2026766A1 (de) 2006-05-17 2009-02-25 Synthon B.V. Tabletten-zusammensetzung mit verlängerter freisetzung von tamsulosin
SI2037936T1 (sl) 2006-06-21 2014-11-28 Opko Renal, Llc Postopek zdravljenja in prepreäśevanja sekundarnega hiperparatiroidizma
JP2008007458A (ja) * 2006-06-29 2008-01-17 Freunt Ind Co Ltd レイヤリング用核粒子とその製造方法
CA2670636A1 (en) 2006-11-27 2008-06-05 H. Lundbeck A/S Heteroaryl amide derivatives
RU2436581C2 (ru) 2007-02-01 2011-12-20 Дзе Иамс Компани Способ уменьшения воспаления и снижения стресса у млекопитающего
EP2148683A4 (de) 2007-04-25 2012-09-12 Proventiv Therapeutics Llc Verfahren zur sicheren und wirksamen behandlung und prävention von sekundärer hyperparathyreose bei chronischer nierenerkrankung
ES2403107T3 (es) 2007-04-25 2013-05-14 Cytochroma Inc. Método de tratamiento de insuficiencia y deficiencia de vitamina D
DK2148661T3 (da) 2007-04-25 2013-03-25 Cytochroma Inc Orale præparater med kontrolleret afgivelse omfattende vitamin D-forbindelse og voksagtig bærer
EP2173329A1 (de) * 2007-07-03 2010-04-14 Synthon B.V. Tolterodinkügelchen
US8110226B2 (en) * 2007-07-20 2012-02-07 Mylan Pharmaceuticals Inc. Drug formulations having inert sealed cores
US8486452B2 (en) 2007-07-20 2013-07-16 Mylan Pharmaceuticals Inc. Stabilized tolterodine tartrate formulations
WO2009019599A2 (en) * 2007-08-08 2009-02-12 Themis Laboratories Private Limited Extended release compositions comprising tolterodine
CN101801350A (zh) 2007-08-13 2010-08-11 阿巴斯迪特宁医药有限公司 抗滥用药物、使用方法和制备方法
US20090192228A1 (en) * 2008-01-28 2009-07-30 Actavis Group Ptc Ehf Controlled-Release Tolterodine Compositions and Methods
US20090214665A1 (en) * 2008-02-26 2009-08-27 Lai Felix S Controlled Release Muscarinic Receptor Antagonist Formulation
CA2629099A1 (en) * 2008-04-01 2009-10-01 Pharmascience Inc. Novel oral controlled release pharmaceutical formulations
CA2714996C (en) 2008-04-02 2020-04-07 Cytochroma Inc. Methods, compositions, uses, and kits useful for vitamin d deficiency and related disorders
US20090311317A1 (en) * 2008-05-14 2009-12-17 Capricorn Pharma Inc. Modified release tolterodine formulations
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
US8465770B2 (en) 2008-12-24 2013-06-18 Synthon Bv Low dose controlled release tablet
US9078830B2 (en) 2009-07-31 2015-07-14 Ranbaxy Laboratories Limited Multi-layered, multiple unit pharmaceutical compositions
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
WO2011061616A2 (en) 2009-11-23 2011-05-26 Micro Labs Limited Extended release compositions containing tolterodine and process for preparing the same
WO2011095388A1 (en) 2010-02-04 2011-08-11 Synthon Bv Tolterodine bead
PT2552484T (pt) 2010-03-29 2020-04-03 Opko Ireland Global Holdings Ltd Métodos e composições para redução dos níveis de parafróides
NZ706991A (en) 2010-03-29 2016-08-26 Ferring Bv A fast dissolving pharmaceutical composition
JO3112B1 (ar) 2010-03-29 2017-09-20 Ferring Bv تركيبة دوائية سريعة التحلل
CA2796877A1 (en) 2010-04-30 2011-11-03 Merck Sharp & Dohme Corp. Novel beta 3 adrenergic receptor agonists
US20120040008A1 (en) * 2010-08-11 2012-02-16 Ashish Chatterji Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
WO2012154770A1 (en) 2011-05-10 2012-11-15 Theravida, Inc. Combinations of tolterodine and salivary stimulants for the treatment of overactive bladder
GR1007628B (el) 2011-07-27 2012-06-29 Φαρματεν Αβεε, Φαρμακευτικο σκευασμα περιεχον εναν αντιμουσκαρινικο παραγοντα και μεθοδος για την παρασκευη αυτου
KR20140061438A (ko) 2011-09-16 2014-05-21 훼링 비.브이. 속용성 약학 조성물
JP5553132B2 (ja) * 2011-09-30 2014-07-16 アステラス製薬株式会社 粒子状医薬組成物
EP2872177B1 (de) 2012-07-12 2017-12-20 Ferring BV Diclofenac-formulierungen
MX2015003658A (es) * 2012-09-20 2015-09-25 Ohr Pharma Llc Microparticulas biodegradables de capas multiples para la liberacion sostenida de agentes terapeuticos.
US20150306170A1 (en) * 2012-11-21 2015-10-29 Ferring B.V. Composition for immediate and extended release
TW201422254A (zh) 2012-11-21 2014-06-16 Ferring Bv 用於速釋及延釋的組成物
NZ629598A (en) * 2013-03-13 2016-10-28 Advanced Bionutrition Corp Stable bioactive substances and methods of making
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 d 방출 제형
US20140275038A1 (en) 2013-03-15 2014-09-18 Inspirion Delivery Technologies, Llc Abuse deterrent compositions and methods of use
AU2014246617A1 (en) 2013-12-23 2015-07-09 Sun Pharmaceutical Industries Limited Multi-layered, multiple unit pharmaceutical compositions
CR20170085A (es) 2014-08-07 2017-04-25 Opko Ireland Global Holdings Ltd Terapia adjuntiva con 25-hidroxi vitamina d
US10729685B2 (en) 2014-09-15 2020-08-04 Ohemo Life Sciences Inc. Orally administrable compositions and methods of deterring abuse by intranasal administration
CA2936740C (en) * 2014-10-31 2017-10-10 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
EP3431107A4 (de) * 2016-02-23 2019-11-13 Nipro Corporation Partikel einer pharmazeutischen zusammensetzung und im mund zerfallende zubereitung damit
BR112018069727A2 (pt) 2016-03-28 2019-02-05 Opko Ireland Global Holdings Ltd métodos de tratamento com vitamina d

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1144911B (it) 1981-03-19 1986-10-29 Pharmatec Spa Composizione farmaceutica a rilascio controllato contenente ibuprofen
JPH07107450A (ja) 1993-10-08 1995-04-21 Hitachi Ltd 情報通信装置
JP3453186B2 (ja) 1994-04-14 2003-10-06 共和薬品工業株式会社 徐放性マイクロカプセルおよびその製造方法
SE9402422D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New beads for controlled release and a pharmaceutical preparation containing the same
US5645858A (en) * 1994-10-06 1997-07-08 Ortho Pharmaceutical Corporation Multilayered controlled release pharmaceutical dosage form
US5567441A (en) 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
EP0924983A4 (de) 1996-07-19 1999-08-25 Gunnar Aberg S(-)-tolterodin in der behandlung urinärer und gastrointestinaler störungen
US6312728B1 (en) * 1998-07-07 2001-11-06 Cascade Development, Inc. Sustained release pharmaceutical preparation

Also Published As

Publication number Publication date
JP3616011B2 (ja) 2005-02-02
BRPI9915142B1 (pt) 2015-08-25
SK6252001A3 (en) 2002-01-07
EA200100538A1 (ru) 2001-10-22
BR9915142A (pt) 2001-08-07
HRP20010333B1 (en) 2004-10-31
AU762410B2 (en) 2003-06-26
HUP0105038A2 (en) 2002-06-29
BG105582A (en) 2001-12-29
KR20010075695A (ko) 2001-08-09
HUP0105038A3 (en) 2006-07-28
OA11673A (en) 2005-01-12
AP1323A (en) 2004-11-05
MY122195A (en) 2006-03-31
WO2000027364A1 (en) 2000-05-18
HK1040917B (zh) 2005-05-27
MA25325A1 (fr) 2001-12-31
NO331399B1 (no) 2011-12-19
NO20012314L (no) 2001-07-09
EP1128819B1 (de) 2003-08-20
UA57165C2 (uk) 2003-06-16
ID30039A (id) 2001-11-01
IS5936A (is) 2001-05-09
HK1040917A1 (en) 2002-06-28
BG65149B1 (bg) 2007-04-30
IS2370B (is) 2008-06-15
YU33101A (sh) 2003-10-31
CZ20011627A3 (cs) 2001-10-17
ES2204193T3 (es) 2004-04-16
PT1128819E (pt) 2003-12-31
DE69910604T2 (de) 2004-06-24
EE200100254A (et) 2002-12-16
HRP20010333A2 (en) 2003-04-30
TWI267385B (en) 2006-12-01
CN1326339A (zh) 2001-12-12
CA2350061C (en) 2005-05-17
ATE247458T1 (de) 2003-09-15
HU226582B1 (en) 2009-04-28
CZ299582B6 (cs) 2008-09-10
EE05232B1 (et) 2009-12-15
NZ511430A (en) 2003-05-30
IL142809A0 (en) 2002-03-10
CN1169522C (zh) 2004-10-06
PL348612A1 (en) 2002-06-03
AR027815A1 (es) 2003-04-16
KR100467384B1 (ko) 2005-01-24
PL195780B1 (pl) 2007-10-31
SE9803871D0 (sv) 1998-11-11
JP2003517446A (ja) 2003-05-27
BRPI9915142B8 (pt) 2021-05-25
NO20012314D0 (no) 2001-05-10
AU1436600A (en) 2000-05-29
SK284758B6 (sk) 2005-11-03
GEP20022833B (en) 2002-11-25
DK1128819T3 (da) 2003-12-01
SI1128819T1 (en) 2003-12-31
AP2001002166A0 (en) 2001-06-30
CA2350061A1 (en) 2000-05-18
RS49891B (sr) 2008-08-07
ZA200103575B (en) 2002-05-03
EA005074B1 (ru) 2004-10-28
US6911217B1 (en) 2005-06-28
EP1128819A1 (de) 2001-09-05
TWI222879B (en) 2004-11-01

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