SG10201913863TA - Methods of vitamin d treatment - Google Patents

Methods of vitamin d treatment

Info

Publication number
SG10201913863TA
SG10201913863TA SG10201913863TA SG10201913863TA SG10201913863TA SG 10201913863T A SG10201913863T A SG 10201913863TA SG 10201913863T A SG10201913863T A SG 10201913863TA SG 10201913863T A SG10201913863T A SG 10201913863TA SG 10201913863T A SG10201913863T A SG 10201913863TA
Authority
SG
Singapore
Prior art keywords
vitamin
treatment
methods
Prior art date
Application number
SG10201913863TA
Inventor
Joel Z Melnick
Charles W Bishop
P Martin Petkovich
Stephen A Strugnell
Original Assignee
Opko Ireland Global Holdings Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Opko Ireland Global Holdings Limited filed Critical Opko Ireland Global Holdings Limited
Publication of SG10201913863TA publication Critical patent/SG10201913863TA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5939,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5929,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/20Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
SG10201913863TA 2016-03-28 2017-03-28 Methods of vitamin d treatment SG10201913863TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662314359P 2016-03-28 2016-03-28

Publications (1)

Publication Number Publication Date
SG10201913863TA true SG10201913863TA (en) 2020-03-30

Family

ID=59520857

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201913863TA SG10201913863TA (en) 2016-03-28 2017-03-28 Methods of vitamin d treatment
SG11201808227YA SG11201808227YA (en) 2016-03-28 2017-03-28 Methods of vitamin d treatment

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201808227YA SG11201808227YA (en) 2016-03-28 2017-03-28 Methods of vitamin d treatment

Country Status (20)

Country Link
US (2) US11173168B2 (en)
EP (1) EP3436026A1 (en)
JP (2) JP7032322B2 (en)
KR (3) KR20230056790A (en)
CN (1) CN108883120A (en)
AU (2) AU2017253821B2 (en)
BR (1) BR112018069727A2 (en)
CA (1) CA3018019A1 (en)
CL (1) CL2018002734A1 (en)
CO (1) CO2018011063A2 (en)
CR (1) CR20180510A (en)
EA (1) EA201892189A1 (en)
EC (1) ECSP18080294A (en)
IL (2) IL290855B1 (en)
MX (2) MX2018011820A (en)
MY (1) MY198547A (en)
PH (1) PH12018502027A1 (en)
SG (2) SG10201913863TA (en)
TW (2) TW202214257A (en)
WO (1) WO2017182237A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112074275A (en) * 2018-04-03 2020-12-11 欧普科爱尔兰环球控股有限公司 Use of calcifediol in the treatment of obesity in surgical patients
MX2020011741A (en) 2019-02-06 2021-03-02 Eirgen Pharma Ltd Method of controlling progression of hyperparathyroidism with calcifediol, and compositions for use therein.
CN116033940A (en) 2020-04-06 2023-04-28 艾尔金制药有限公司 Activating endogenous antibacterial agent for treating SARS-COV-2 infection
IL297885A (en) 2020-05-31 2023-01-01 Eirgen Pharma Ltd Hard capsule dosage form and uses thereof
WO2022224001A1 (en) 2021-04-22 2022-10-27 Faes Farma, S.A. Universal dosage regime of 25-hydroxy vitamin d3

Family Cites Families (247)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3565924A (en) 1968-07-01 1971-02-23 Wisconsin Alumni Res Found 25-hydroxycholfcalciferol
US3833622A (en) 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US3974272A (en) 1972-09-01 1976-08-10 Merck & Co., Inc. Palatable cholestyramine coacervate compositions
US3880894A (en) 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
US4004003A (en) 1974-08-28 1977-01-18 The Upjohn Company 25-Hydroxycalciferol compounds for treatment of steroid-induced osteoporosis
US4335120A (en) 1979-03-21 1982-06-15 Hoffmann-La Roche Inc. Administration of biologically active vitamin D3 and vitamin D2 materials
US4230701A (en) 1979-03-21 1980-10-28 Hoffmann-La Roche Inc. Administration of biologically active vitamin D3 and vitamin D2 materials
JPS55139320A (en) 1979-04-16 1980-10-31 Teijin Ltd Bone metabolism regulator
US4442093A (en) 1981-05-15 1984-04-10 Kureha Kagaku Kogyo Kabushiki Kaisha Method for administering 24,25-dihydroxycholecalciferol to persons suffering from hypercalcemia
JPS57188520A (en) 1981-05-15 1982-11-19 Kureha Chem Ind Co Ltd Antihyperkalemia
JPS5832823A (en) 1981-08-20 1983-02-25 Chugai Pharmaceut Co Ltd Cancer eliminating agent
JPS58206524A (en) 1982-05-26 1983-12-01 Kureha Chem Ind Co Ltd Antitumor agent
US4448721A (en) 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
US4721613A (en) 1982-12-13 1988-01-26 Alza Corporation Delivery system comprising means for shielding a multiplicity of reservoirs in selected environment of use
JPS59155309A (en) 1983-02-22 1984-09-04 Teijin Ltd Active type vitamin d3 composition and its preparation
US4684524A (en) 1984-03-19 1987-08-04 Alza Corporation Rate controlled dispenser for administering beneficial agent
US4555364A (en) 1984-11-01 1985-11-26 Wisconsin Alumni Research Foundation Method for preparing 1-hydroxyvitamin D compounds
US4695591A (en) 1985-03-29 1987-09-22 Schering Corporation Controlled release dosage forms comprising hydroxypropylmethylcellulose
US4668517A (en) 1985-04-04 1987-05-26 Norwich Eaton Pharmaceuticals, Inc. Furazolidone dosage form
EP0207638B1 (en) 1985-06-04 1990-12-19 Teijin Limited Sustained-release pharmaceutical preparation
JPS61293911A (en) 1985-06-24 1986-12-24 Teisan Seiyaku Kk Sustained release preparation
US5167965A (en) 1987-02-09 1992-12-01 The Dow Chemical Company Palatable cholestyramine granules, tablets and methods for preparation thereof
US4892821A (en) 1987-07-08 1990-01-09 Taisho Pharmaceutical Co., Ltd. Method for preparing vitamin D compounds
US4997824A (en) 1987-07-22 1991-03-05 Teva Pharmaceutical Industries Ltd. Combination of cholecalciferol derivatives for the treatment of renal bone disease
US5104864A (en) 1988-08-02 1992-04-14 Bone Care International, Inc. Method for treating and preventing loss of bone mass
US5869473A (en) 1988-08-02 1999-02-09 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US5602116A (en) 1988-08-02 1997-02-11 Bone Care International, Inc. Method for treating and preventing secondary hyperparathyroidism
JP2893191B2 (en) 1988-11-08 1999-05-17 武田薬品工業株式会社 Controlled release matrix agent
JP2525478B2 (en) 1989-03-01 1996-08-21 帝人株式会社 Active Vitamin D with improved stability (3) Lower solid preparation
JPH02240024A (en) 1989-03-13 1990-09-25 Ss Pharmaceut Co Ltd Composition for active type vitamin d3s preparation
US5026559A (en) 1989-04-03 1991-06-25 Kinaform Technology, Inc. Sustained-release pharmaceutical preparation
GB9004544D0 (en) 1990-03-01 1990-04-25 Leo Pharm Prod Ltd Novel treatment ii
JP2845342B2 (en) 1990-04-28 1999-01-13 大正製薬株式会社 Vitamin D Lower 3 Derivative-Containing Solid Preparation Composition
JPH04198129A (en) 1990-11-28 1992-07-17 Sumitomo Pharmaceut Co Ltd Active type vitamin d>=3*s-containing composition
JP2893140B2 (en) 1990-11-30 1999-05-17 エスエス製薬株式会社 Stable vitamin D preparation
JPH04288016A (en) 1991-03-14 1992-10-13 Tokai Capsule Kk Production of soft capsule agent of active type vitamin d3s
ES2094290T3 (en) 1991-04-09 1997-01-16 Takeda Chemical Industries Ltd STABILIZED PREPARATION OF VITAMIN D.
US5693615A (en) 1991-06-05 1997-12-02 The Procter & Gamble Company Therapeutic compositions for osteoinduction
US6313146B1 (en) 1991-08-23 2001-11-06 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6011068A (en) 1991-08-23 2000-01-04 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6031003A (en) 1991-08-23 2000-02-29 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6001884A (en) 1991-08-23 1999-12-14 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5266331A (en) 1991-11-27 1993-11-30 Euroceltique, S.A. Controlled release oxycodone compositions
US5472712A (en) 1991-12-24 1995-12-05 Euroceltique, S.A. Controlled-release formulations coated with aqueous dispersions of ethylcellulose
US5160742A (en) 1991-12-31 1992-11-03 Abbott Laboratories System for delivering an active substance for sustained release
US5795882A (en) 1992-06-22 1998-08-18 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
WO1994000128A1 (en) 1992-06-22 1994-01-06 Lunar Corporation ORAL 1α-HYDROXYPREVITAMIN D
US5354743A (en) 1992-09-15 1994-10-11 Thys Jacobs Susan Method for the treatment of premenstrual syndrome with vitamin D
US5431917A (en) 1992-10-08 1995-07-11 Japan Elanco Company, Ltd. Hard capsule for pharmaceutical drugs and method for producing the same
US5342626A (en) 1993-04-27 1994-08-30 Merck & Co., Inc. Composition and process for gelatin-free soft capsules
JP2684587B2 (en) 1993-06-21 1997-12-03 呉羽化学工業株式会社 Inhibitor of bone loss in renal osteodystrophy
US6121469A (en) 1993-12-23 2000-09-19 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs
JPH07242550A (en) 1994-03-02 1995-09-19 Teijin Ltd Therapeutic agent for secondary hyperparathyroidism
IL110117A0 (en) 1994-06-24 1994-10-07 Univ Ben Gurion Pharmaceutical compositions comprising vitamin-d analogs
SE9402422D0 (en) 1994-07-08 1994-07-08 Astra Ab New beads for controlled release and a pharmaceutical preparation containing the same
WO1996003113A1 (en) 1994-07-22 1996-02-08 G.D. Searle & Co. Self-emulsifying drug delivery system
JPH0892098A (en) 1994-09-27 1996-04-09 Teijin Ltd Therapeutic medicine for consumption
EP1275635A1 (en) 1994-10-21 2003-01-15 Nps Pharmaceuticals, Inc. Calcium receptor-active compounds
US5756123A (en) 1994-12-01 1998-05-26 Japan Elanco Co., Ltd. Capsule shell
US20040043971A1 (en) 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
US6376479B1 (en) 1995-04-03 2002-04-23 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US20020183288A1 (en) 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US6242434B1 (en) 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
EP1021401A1 (en) 1995-09-21 2000-07-26 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
DE19549243A1 (en) 1995-12-21 1997-06-26 Schering Ag Pharmaceutical preparations containing clathrates of cyclodextrins and unnatural vitamin D analogues
NO971934L (en) 1996-05-23 1997-11-24 Hoffmann La Roche Fluorinated vitamin D3 analogues
US5939408A (en) 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
EP0949927B1 (en) 1996-08-26 2002-10-16 Takeda Chemical Industries, Ltd. Pharmaceutical composition containing osteogenesis-promoting substance and a polyethylene glycol
US5958451A (en) 1996-09-03 1999-09-28 Yung Shin Pharm Ind. Co., Ltd. Process for producing porous, controlled-release capsules and encapsulated composition
US5976784A (en) 1996-09-20 1999-11-02 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US8828432B2 (en) 1996-10-28 2014-09-09 General Mills, Inc. Embedding and encapsulation of sensitive components into a matrix to obtain discrete controlled release particles
CA2269806C (en) 1996-10-28 2006-01-24 Bernhard H. Van Lengerich Embedding and encapsulation of controlled release particles
JPH10158171A (en) 1996-12-02 1998-06-16 Kita:Kk Intraocular administrating agent formulating vitamin d compound therein
US20020128240A1 (en) 1996-12-30 2002-09-12 Bone Care International, Inc. Treatment of hyperproliferative diseases using active vitamin D analogues
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
US20030129194A1 (en) 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
US6034075A (en) 1997-03-20 2000-03-07 The Trustees Of Columbia University In The City Of New York Method of treating polycystic ovarian syndrome
US5872113A (en) 1997-05-16 1999-02-16 Syntex (U.S.A.) Inc. Fluorinated vitamin D3 analogs
AU8293498A (en) 1997-07-02 1999-01-25 Euro-Celtique S.A. Stabilized sustained release tramadol formulations
JPH1175863A (en) 1997-07-10 1999-03-23 Kyowa Hakko Kogyo Co Ltd 25-hydroxyvitamin d3-1-alpha-hydroxylase and dna encoding the same
US6096876A (en) 1997-08-06 2000-08-01 Shriners Hospitals For Children 1-α-hydroxylase materials and methods
US20020076442A1 (en) 1997-09-02 2002-06-20 Martin Burke Vitamin d3 analog loaded polymer formulations for cancer and neurodegenerative disorders
US5919986A (en) 1997-10-17 1999-07-06 Hoffmann-La Roche Inc. D-homo vitamin D3 derivatives
JPH11158074A (en) 1997-12-03 1999-06-15 Hayashi Tomie Amino acid-rich active vitamin d potentiation composition
US20030059471A1 (en) 1997-12-15 2003-03-27 Compton Bruce Jon Oral delivery formulation
CA2323782A1 (en) 1998-03-25 1999-09-30 Cutanogen, Inc. Methods for prevention and treatment of cancer
EP1064000B1 (en) 1998-03-27 2011-07-06 Oregon Health & Science University Vitamin d and its analogs in the treatment of tumors and other hyperproliferative disorders
US6197340B1 (en) 1998-05-28 2001-03-06 Medical Research Institute Controlled release lipoic acid
US8133694B2 (en) 1998-06-25 2012-03-13 Immundiagnostik Ag Functional vitamin D derivatives and method of determining 25-hydroxy- and 1α, 25-dihydroxy vitamin D
US6214376B1 (en) 1998-08-25 2001-04-10 Banner Pharmacaps, Inc. Non-gelatin substitutes for oral delivery capsules, their composition and process of manufacture
CZ302630B6 (en) 1998-08-27 2011-08-10 Pharmacia & Upjohn Ab Pharmaceutical composition containing tolterodine or tolterodine-related compound
SE9803871D0 (en) 1998-11-11 1998-11-11 Pharmacia & Upjohn Ab Therapeutic method and formulation
US6139875A (en) 1998-09-29 2000-10-31 Eastman Chemical Company Aqueous enteric coating composition and low gastric permeability enteric coating
WO2000018374A1 (en) 1998-10-01 2000-04-06 Elan Pharma International, Ltd. Controlled release nanoparticulate compositions
PT1119345E (en) 1998-10-09 2009-07-27 Gen Mills Inc Encapsulation of sensitive liquid components into a matrix to obtain discrete shelf-stable particles
JP3449253B2 (en) 1998-10-29 2003-09-22 シオノギクオリカプス株式会社 Manufacturing method of hard capsule
JP2000206312A (en) 1998-11-12 2000-07-28 Olympus Optical Co Ltd Optical element
ATE260642T1 (en) 1998-12-17 2004-03-15 Alza Corp CONVERSION OF LIQUID-FILLED GELATIN CAPSULES INTO SYSTEMS WITH CONTROLLED ACTIVE RELEASE THROUGH MULTIPLE COATINGS
US6342249B1 (en) 1998-12-23 2002-01-29 Alza Corporation Controlled release liquid active agent formulation dosage forms
US6432936B1 (en) 1999-01-20 2002-08-13 Wisconsin Alumni Research Foundation Crystalline 1α-hydroxyvitamin D2 and method of purification thereof
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
ES2274785T3 (en) 1999-04-01 2007-06-01 Johns Hopkins University ANALOGS OF 1-ALPHA, 25-DIHYDROXI VITAMIN D3 NON-CALCEMIC, ANTIPROLIFERATIVE, TRANSCRIPTIONALLY ACTIVE CONTAINING SULFUR.
US7648826B1 (en) 1999-04-02 2010-01-19 The Regents Of The University Of California Detecting CYP24 expression level as a marker for predisposition to cancer
DE19916419B4 (en) 1999-04-08 2005-06-16 Schering Ag Combination preparation of vitamin D metabolites or vitamin D analogues and an estrogen partial agonist for the treatment of osteoporosis
WO2000072831A1 (en) 1999-05-27 2000-12-07 Drugtech Corporation Nutritional formulations
US6340473B1 (en) 1999-07-07 2002-01-22 R.P. Scherer Technologies, Inc. Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same
US6051567A (en) 1999-08-02 2000-04-18 Abbott Laboratories Low oxygen content compositions of 1α, 25-dihydroxycholecalciferol
US6274169B1 (en) 1999-08-02 2001-08-14 Abbott Laboratories Low oxygen content compostions of 1α, 25-dihydroxycholecalciferol
US6893658B1 (en) 1999-08-31 2005-05-17 Chugai Seiyaku Kabushiki Kaisha Soft capsules
US20060034937A1 (en) 1999-11-23 2006-02-16 Mahesh Patel Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
GB0007419D0 (en) 2000-03-27 2000-05-17 Smithkline Beecham Gmbh Composition
US6375981B1 (en) 2000-06-01 2002-04-23 A. E. Staley Manufacturing Co. Modified starch as a replacement for gelatin in soft gel films and capsules
WO2002006218A2 (en) 2000-07-18 2002-01-24 Bone Care International, Inc. STABILIZED 1α-HYDROXY VITAMIN D
US6491950B1 (en) 2000-08-07 2002-12-10 Kos Pharmaceuticals, Inc. Controlled release pharmaceutical composition
MXPA03001854A (en) 2000-08-29 2004-12-03 Nisshin Kasei Co Ltd Hard capsule.
US6887493B2 (en) 2000-10-25 2005-05-03 Adi Shefer Multi component controlled release system for oral care, food products, nutraceutical, and beverages
KR101045144B1 (en) 2000-10-30 2011-06-30 유로-셀티크 소시에떼 아노뉨 Controlled release hydrocodone formulations
US6479649B1 (en) 2000-12-13 2002-11-12 Fmc Corporation Production of carrageenan and carrageenan products
JP2002302447A (en) 2001-04-03 2002-10-18 Shimizu Pharmaceutical Co Ltd Cancer therapeutic agent for topical administration
HUP0304078A2 (en) 2001-05-15 2004-04-28 Warner-Lambert Co. Llc Compaction process for manufacture of sodium phenytoin dosage form
US7846475B2 (en) 2001-07-05 2010-12-07 Wakunaga Pharmaceutical Co., Ltd. Soft capsules
US6870833B2 (en) 2001-07-20 2005-03-22 Net2Phone, Inc. Active voice messaging
US7166585B2 (en) 2001-08-22 2007-01-23 Cytochroma Inc. 24-Sulfur-substituted analogs of 1α,25-dihydroxy vitamin D3
US7033996B2 (en) 2001-08-31 2006-04-25 University Of Medicine & Dentistry Of New Jersey Method for the treatment of vitamin D related disease
DE10149674A1 (en) 2001-10-09 2003-04-24 Apogepha Arzneimittel Gmbh Orally administered composition for sustained release of propiverine, useful for treatment of hypertonic bladder disorders, especially by once-daily administration
JP4436674B2 (en) 2001-10-12 2010-03-24 ジョンズ ホプキンス ユニバーシティ Hypocalcemic oxime analog of 1α, 25-dihydroxyvitamin D3
US7056655B2 (en) 2001-11-02 2006-06-06 Scantibodies Laboratory, Inc. Methods for monitoring and guiding therapeutic suppression of parathyroid hormone in renal patients having secondary hyperparathyroidism
US6524788B1 (en) 2001-11-02 2003-02-25 Thomas L. Cantor Methods for monitoring and guiding therapeutic suppression of parathyroid hormone in renal patients having secondary hyperparathyroidism
ITMI20012366A1 (en) 2001-11-09 2003-05-09 Farmatron Ltd THERAPEUTIC SYSTEMS STABILIZED WITH IMMEDIATE RELEASE AND / OR MODIFIED FOR THE ORAL ADMINISTRATION OF ACTIVE AND / OR EXCIPIENT PRINCIPLES AND / OR WINGS
KR20100047349A (en) 2001-11-22 2010-05-07 모리시타 진탄 가부시키가이샤 Non-gelatinous capsule film compositions and capsules using the same
GB0128415D0 (en) 2001-11-27 2002-01-16 Univ Sheffield Medicaments
EA008072B1 (en) 2001-12-03 2007-02-27 Новацея, Инк. Pharmaceutical compositions comprising active vitamin d compounds
US6627622B2 (en) 2002-02-18 2003-09-30 Wisconsin Alumni Research Foundation (20S)-1α-hydroxy-2-methylene-19-nor-bishomopregnacalciferol and its uses
FR2829142B1 (en) 2001-12-27 2004-02-13 Ulice FILMOGENEOUS COMPOSITION OF HETEROXYLANE FOR THE MANUFACTURE OF CAPSULES THUS OBTAINED
US7632518B2 (en) 2002-01-15 2009-12-15 Dsm Ip Assets B.V. 25-hydroxy vitamin D3 compositions
US6949256B2 (en) 2002-01-18 2005-09-27 Banner Pharmacaps, Inc. Non-gelatin capsule shell formulation
NO20021592D0 (en) 2002-04-04 2002-04-04 Fmc Biopolymer As Polysaccharide Capsules and Method of Preparation thereof
WO2003086415A1 (en) 2002-04-05 2003-10-23 Merck & Co., Inc. Method for inhibiting bone resorption with an alendronate and vitamin d formulation
WO2003086267A2 (en) 2002-04-10 2003-10-23 Miller Fred H Multi-phase, multi-compartment capsular system
US7288407B2 (en) 2002-05-02 2007-10-30 Cytochroma, Inc. Stable cytochrome P450 24 (CYP24) expressing cell line and methods and uses thereof
US7101865B2 (en) 2002-06-13 2006-09-05 Cytochroma Inc. 24-sulfoximine vitamin D3 compounds
EP1519717B1 (en) 2002-07-05 2010-09-29 Temrel Limited Controlled release composition
TWI336260B (en) 2002-07-25 2011-01-21 Glaxo Group Ltd Dosage form suitable for retaining drug substance
PT1539115E (en) 2002-07-29 2008-01-14 Alza Corp Methods and dosage forms for controlled delivery of paliperidone
US8268352B2 (en) 2002-08-05 2012-09-18 Torrent Pharmaceuticals Limited Modified release composition for highly soluble drugs
WO2004028515A1 (en) 2002-09-26 2004-04-08 Young-Kweon Choi Matrix type patch for transdermal administration of vitamin d analog and the use thereof
US20050101576A1 (en) 2003-11-06 2005-05-12 Novacea, Inc. Methods of using vitamin D compounds in the treatment of myelodysplastic syndromes
US8999372B2 (en) 2002-11-14 2015-04-07 Cure Pharmaceutical Corporation Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use
JP2004175750A (en) 2002-11-28 2004-06-24 Kose Corp Dermopathy inhibitor and dermopathy improving agent, and skin care preparation for external use containing them
US20050026877A1 (en) 2002-12-03 2005-02-03 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
DE20321698U1 (en) 2002-12-16 2008-12-24 Teva Pharmaceutical Industries Ltd. A medicament for increasing the bioavailability of alendronate or another bisphosphonate by administering a pre-dose of a vitamin D derivative
GB2411116B (en) 2002-12-16 2009-04-29 Teva Pharma Increasing the bioavailability of alendronate by predose administration of alphacalcidol
CA2510228C (en) 2002-12-18 2012-10-30 Johns Hopkins University 25-so2-substituted analogs of 1.alpha.,25-dihydroxyvitamin d3
DE602004015246D1 (en) 2003-02-11 2008-09-04 Alza Corp METHOD AND DOSAGE FORMS WITH MODIFIED LAYERING GEOMETRY
BRPI0409336A (en) 2003-04-14 2006-04-25 Fmc Corp release system comprising a thermoreversibly, homogeneous gel film, release system film, and process for preparing the release system thereof
US7816341B2 (en) 2003-04-14 2010-10-19 Fmc Corporation Homogeneous, thermoreversible gel containing reduced viscosity carrageenan and products made therefrom
US20070032461A1 (en) 2003-04-30 2007-02-08 Bioxell S.P.A. 1,3 Aclyated 24-keto-vitamin d3 compounds and methods of use thereof
AU2004237437B2 (en) 2003-05-07 2011-01-20 Osteologix A/S Controlled release composition containing a strontium salt
EP1479677A1 (en) 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH New indole derivatives as factor xa inhibitors
CA2529495C (en) 2003-06-16 2013-02-05 Solx, Inc. Shunt for the treatment of glaucoma
ATE536861T1 (en) 2003-06-26 2011-12-15 Control Delivery Sys Inc BIOERODABLE SUSTAINED RELEASE DRUG DELIVERY SYSTEMS
AU2003903382A0 (en) 2003-07-03 2003-07-17 Medvet Science Pty Ltd Inhibition of calcitriol mediated cyp24 induction screening for compounds therefor and uses thereof
CA2531136A1 (en) 2003-07-04 2005-01-13 Nycomed Danmark Aps Parathyroid hormone (pth) containing pharmaceutical compositions for oral use
US20050148557A1 (en) 2003-07-29 2005-07-07 Jin Tian Use of Vitamin Ds to treat kidney disease
US20050124591A1 (en) 2003-07-29 2005-06-09 Jin Tian Use of vitamin Ds to treat kidney disease
JP5026077B2 (en) 2003-09-12 2012-09-12 アムジエン・インコーポレーテツド Calcium receptor-active compound rapid dissolution formulation
US7053075B2 (en) 2003-11-25 2006-05-30 Deluca Hector F Methods for reducing body fat using vitamin D compounds
US7427670B2 (en) 2003-12-19 2008-09-23 Cytochroma Inc. Cytochrome P450 24 (CYP24) monoclonal antibody and methods and uses thereof
US20060009425A1 (en) 2004-05-28 2006-01-12 Leticia Delgado-Herrera Oral formulations of paricalcitol
US9750797B2 (en) 2004-06-16 2017-09-05 Virbac Corporation Sustained release vaccine composition
US20050287213A1 (en) 2004-06-28 2005-12-29 Wong Patrick S Dosage forms for low solubility and or low dissolution rate free acid pharmaceutical agents
US20060019933A1 (en) 2004-07-22 2006-01-26 David Boardman Process for preparing stabilized vitamin D
AU2005266459A1 (en) 2004-07-29 2006-02-02 Sanofi-Aventis Pharmaceutical multilayer tablet for controlled release of active ingredients with highly pH-dependent solubility
US8231896B2 (en) 2004-11-08 2012-07-31 R.P. Scherer Technologies, Llc Non-gelatin soft capsule system
WO2006059180A2 (en) 2004-12-03 2006-06-08 Council Of Scientific And Industrial Research Process of preparation of biodegradable films from semi refined kappa carrageenan
US8318210B2 (en) 2005-02-28 2012-11-27 Neos Therapeutics, Lp Compositions and methods of making sustained release liquid formulations
US7745226B2 (en) 2005-04-06 2010-06-29 Quest Diagnostics Investments Incorporated Methods for detecting vitamin D metabolites
WO2006113505A2 (en) 2005-04-15 2006-10-26 Clarus Therapeutics, Inc. Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same
US20060257481A1 (en) 2005-04-21 2006-11-16 Decode Genetics Ehf. Sustained release formulation and dosing schedule of leukotriene synthesis inhibitor for human therapy
US9205047B2 (en) 2005-04-25 2015-12-08 The Governing Council Of The University Of Toronto Tunable sustained release of a sparingly soluble hydrophobic therapeutic agent from a hydrogel matrix
US20080134937A1 (en) 2005-05-25 2008-06-12 Joo Hwan Yang Cellulose hard capsule enhancing mechanical film strength
AR055099A1 (en) 2005-07-28 2007-08-08 Alza Corp LIQUID FORMULATIONS FOR THE CONTROLLED ADMINISTRATION OF BENCISOXAZOL DERIVATIVES
EP1931711B1 (en) 2005-09-29 2009-04-08 Roche Diagnostics GmbH Antibodies against 25-hydroxyvitamin d
ITFI20050206A1 (en) 2005-09-30 2007-04-01 Valpharma Sa PHARMACEUTICAL COMPOSITION OF CONTROLLED RELEASE OF VENLAFAXINE CHLORIDRATE, AND PROCESS FOR ITS PREPARATION
US20070122477A1 (en) 2005-10-12 2007-05-31 Cytochroma, Inc. Methods and articles for treating 25-hydroxyvitamin D insufficiency and deficiency
CA2627351C (en) 2005-10-26 2012-05-01 Banner Pharmacaps, Inc. Lipophilic vehicle-based dual controlled release matrix system
US8333989B2 (en) 2005-10-26 2012-12-18 Banner Pharmacaps, Inc. Hydrophilic vehicle-based dual controlled release matrix system
MX348439B (en) 2005-11-01 2017-06-13 Cp Kelco Us Inc High viscosity diutan gums and methods of producing.
WO2007068287A1 (en) 2005-12-15 2007-06-21 Laboratoria Qualiphar Sustained release vitamin preparation
MXPA05014091A (en) 2005-12-20 2007-06-20 Leopoldo De Jesus Espinosa Abdala Pharmaceutical compositions containing synthetic steroid derivatives such as tibolone, minerals such as calcium and the active metabolite of vitamin d (calcitrol) for the prevention and treatment of osteoporosis and menopause.
US20070207488A1 (en) 2006-01-31 2007-09-06 Trump Donald L Method for identifying altered vitamin D metabolism
US7528122B2 (en) 2006-02-02 2009-05-05 Wisconsin Alumni Research Foundation Vitamin D analog—NEL, methods and uses thereof
PL1993559T3 (en) 2006-02-03 2017-01-31 Opko Renal, Llc Treating vitamin d insufficiency and deficiency with 25-hydroxyvitamin d2 and 25-hydroxyvitamin d3
GB0606426D0 (en) 2006-03-30 2006-05-10 Novartis Ag Benzimidazole derivatives
CA2660613A1 (en) 2006-06-06 2007-12-21 Fmc Corporation Kappa-2 carrageenan composition and products made therefrom
US20080109983A1 (en) 2006-11-10 2008-05-15 Kegel, Llc Zero Turning Radius Lane Maintenance Machine
LT2679228T (en) 2006-06-21 2018-05-10 Opko Ireland Global Holdings, Ltd. Therapy using vitamin D repletion agent and vitamin D hormone replacement agent
EP1912400A1 (en) 2006-10-10 2008-04-16 Matsushita Electric Industrial Co., Ltd. Method and apparatus for mobile IP route optimization
WO2008050209A1 (en) 2006-10-27 2008-05-02 Pfizer Products Inc. Hydroxypropyl methyl cellulose hard capsules and process of manufacture
US8501717B2 (en) 2007-02-09 2013-08-06 Merck, Sharp & Dohme Corp. Methods to treat and/or prevent mucositis
US8491937B2 (en) 2007-02-15 2013-07-23 Wyeth Llc Stability in vitamin and mineral supplements
US7893357B2 (en) 2007-03-20 2011-02-22 Electrolock, Inc. Roebel winding with conductive felt
WO2008116133A1 (en) 2007-03-21 2008-09-25 Duke University Medication kits and formulations for preventing, treating or reducing secondary fractures after previous fracture
KR101495578B1 (en) 2007-04-25 2015-02-25 사이토크로마 인코포레이티드 Method of treating vitamin d insufficiency and deficiency
JP5647516B2 (en) 2007-04-25 2014-12-24 シトクロマ インコーポレイテッド Methods and compounds for vitamin D therapy
WO2008134512A1 (en) 2007-04-25 2008-11-06 Cytochroma Inc. Oral controlled release compositions comprising vitamin d compound and waxy carrier
JP2010525080A (en) 2007-04-25 2010-07-22 プロヴェンティヴ セラピュティックス リミテッド ライアビリティ カンパニー Safe and effective treatment and prevention method for secondary hyperparathyroidism in chronic kidney disease
US20090004284A1 (en) 2007-06-26 2009-01-01 Watson Pharmaceuticals, Inc. Controlled release tamsulosin hydrochloride formulation
KR100836960B1 (en) 2007-09-07 2008-06-10 주식회사 서울제약 A novel controlled release-niacin formulation
EP2042165A1 (en) 2007-09-28 2009-04-01 Swiss Caps Rechte und Lizenzen AG Hot-melt filled soft capsules
CA2610819A1 (en) 2007-12-12 2008-12-02 Multi Formulations Ltd. Particles in a capsule
CN107028959A (en) 2008-02-13 2017-08-11 帝斯曼知识产权资产管理有限公司 Hyperglycemia is treated with 25 hydroxycholecalciferols
CN101951916A (en) 2008-02-13 2011-01-19 帝斯曼知识产权资产管理有限公司 Use of 25-hydroxy-vitamin D3 to affect human muscle physiology
MX2010008896A (en) 2008-02-13 2010-11-05 Dsm Ip Assets Bv Treating hypertension with 25-hydroxyvitamin d3.
EP2240183A1 (en) 2008-02-13 2010-10-20 DSM IP Assets B.V. Combination of vitamin d and 25-hydroxyvitamin d 3
AU2009214052B2 (en) 2008-02-13 2015-05-07 Dsm Ip Assets B.V. Combined use of 25-hydroxy-vitamin D3 and vitamin D3 for improving bone mineral density and for treating osteoporosis
ES2954932T3 (en) 2008-04-02 2023-11-27 Eirgen Pharma Ltd Useful methods, compositions, uses and kits for vitamin D deficiency and related disorders
SI2321273T1 (en) 2008-07-24 2015-03-31 Wisconsin Alumni Research Foundation Once-a-week administration of 25-hydroxy vitamin d3 to sustain elevated steady-state pharmacokinetic blood concentration
KR101528957B1 (en) 2008-09-24 2015-06-17 에보니크 룀 게엠베하 Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol
ES2425762T3 (en) 2008-10-27 2013-10-17 Roquette Freres Water insoluble polymer: film coatings based on modified starch derivatives for colon-directed release
SG171444A1 (en) 2009-01-23 2011-07-28 Acraf Controlled release pharmaceutical or food formulation and process for its preparation
CH700543A2 (en) 2009-03-03 2010-09-15 Innogel Ag Film based on starch.
JP5696149B2 (en) 2009-09-10 2015-04-08 エフ エム シー コーポレーションFmc Corporation Seamless alginate capsules
IT1396937B1 (en) 2009-11-26 2012-12-20 Bruzzese FORMULATIONS OF BISPHOSPHONATES AND VITAMIN D SUITABLE FOR INTERMITTENT ADMINISTRATION BY INTRAMUSCULAR AND SUBCUTANEOUS
FR2953139B1 (en) 2009-11-27 2012-04-13 Servier Lab PHARMACEUTICAL COMPOSITION COMPRISING STRONTIUM SALT, VITAMIN D AND CYCLODEXTRIN
US8101204B2 (en) 2010-01-14 2012-01-24 Karl Wei Cao Hard capsule composition and method of use
US8101203B2 (en) 2010-01-14 2012-01-24 Karl Wei Cao Hard capsule composition and method of use
WO2011095388A1 (en) 2010-02-04 2011-08-11 Synthon Bv Tolterodine bead
KR102125424B1 (en) 2010-03-29 2020-06-22 사이토크로마 인코포레이티드 Methods and compositions for reducing parathyroid levels
EP2591354B1 (en) 2010-07-07 2016-09-07 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
KR20120005228A (en) 2010-07-08 2012-01-16 주식회사 네비팜 An enteric pharmaceutical composition for the treatment of osteoporosis comprising bisphosphonate and the process thereof
WO2012018329A1 (en) 2010-08-04 2012-02-09 R.P. Scherer Technologies, Llc Film-forming composition for soft capsules
US20120135103A1 (en) 2010-11-30 2012-05-31 Mead Johnson Nutrition Company Staged Infant Feeding Regimen To Promote Healthy Development And Growth
TR201902517T4 (en) 2010-12-06 2019-03-21 Dsm Ip Assets Bv Treatment of conditions associated with increased eotaxin with 25-hydroxyvitamin D3.
CN103282390A (en) 2010-12-28 2013-09-04 未来诊断有限公司 Release reagent for vitamin d
DK2680826T3 (en) 2011-03-02 2017-10-09 D3 Pharma Ltd VITAMIN D COMPOSITION
WO2012145491A2 (en) 2011-04-20 2012-10-26 Jason Fisher Composition and method for enhancing an immune response
EP2700415B1 (en) 2011-04-20 2016-11-30 Suheung Co., Ltd. Non-animal soft capsule shell composition having improved disintegration and shell hardness
CN102771688A (en) 2011-05-13 2012-11-14 富曼实(上海)商贸有限公司 Edible liquid-filled polysaccharide capsule
US20130085121A1 (en) 2011-09-30 2013-04-04 Jianguo Wang Pharmaceutical compositions comprising phosphate binder, calcium receptor-active compound and/or active vitamin d
WO2014029953A1 (en) 2012-08-21 2014-02-27 Cipla Limited Hot melt extruded (hme) pharmaceutical composition of cinacalcet
KR101847947B1 (en) * 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 Stabilized modified release vitamin d formulation
PT106978A (en) 2013-05-31 2014-12-02 Tecnimede Sociedade Tecnico Medicinal S A SOLID ORAL COMPOSITION CONTAINING IBANDRONIC ACID AND VITAMIN D
EP2815745A1 (en) 2013-06-21 2014-12-24 Swiss Caps Rechte und Lizenzen AG Soft shell capsule and process for its manufacture
CN103495176B (en) 2013-10-26 2015-01-28 中山市凯博思淀粉材料科技有限公司 Method for preparing starch-base soft capsules based on co-blending extrusion method
CN103520133B (en) 2013-10-26 2015-02-04 中山市凯博思淀粉材料科技有限公司 Preparation method of starch-based soft capsules
CR20170085A (en) 2014-08-07 2017-04-25 Opko Ireland Global Holdings Ltd ADJUNCTIVE THERAPY WITH 25-HYDROXY VITAMIN D

Also Published As

Publication number Publication date
KR20230054752A (en) 2023-04-25
PH12018502027A1 (en) 2019-02-11
JP2019510045A (en) 2019-04-11
KR20180123100A (en) 2018-11-14
TW201801733A (en) 2018-01-16
ECSP18080294A (en) 2018-11-30
CR20180510A (en) 2019-05-15
IL290855B1 (en) 2024-02-01
MX2018011820A (en) 2019-01-24
TW202214257A (en) 2022-04-16
JP7032322B2 (en) 2022-03-08
JP2022081528A (en) 2022-05-31
CN108883120A (en) 2018-11-23
KR20230056790A (en) 2023-04-27
MX2020011737A (en) 2021-01-08
WO2017182237A1 (en) 2017-10-26
IL261850A (en) 2018-10-31
SG11201808227YA (en) 2018-10-30
MY198547A (en) 2023-09-04
US11173168B2 (en) 2021-11-16
AU2017253821B2 (en) 2022-11-03
EP3436026A1 (en) 2019-02-06
AU2017253821A1 (en) 2018-10-04
IL290855A (en) 2022-04-01
TWI747893B (en) 2021-12-01
BR112018069727A2 (en) 2019-02-05
US20220062304A1 (en) 2022-03-03
CL2018002734A1 (en) 2019-01-04
EA201892189A1 (en) 2019-03-29
JP7382432B2 (en) 2023-11-16
US20190083513A1 (en) 2019-03-21
IL261850B (en) 2022-04-01
CA3018019A1 (en) 2017-10-26
CO2018011063A2 (en) 2019-02-08
AU2023200536A1 (en) 2023-03-09

Similar Documents

Publication Publication Date Title
ZA202006746B (en) Methods of treatment
IL259783A (en) Methods of treatment of malignancies
IL285151B1 (en) Methods of treating fgf21-associated disorders
GB201701673D0 (en) Methods of well treatment
IL290855A (en) Methods of vitamin d treatment
HK1258994A1 (en) Methods for treatment of diseases
GB201410116D0 (en) Method of treatment
GB201416832D0 (en) Methods of treatment
IL253028A0 (en) Method of treatment
HK1249866A1 (en) Methods of treatment with taselisib
EP3490547A4 (en) Method of treatment
GB201408297D0 (en) Treatment of cancer
GB201602802D0 (en) Method of treatment
GB201607388D0 (en) Treatment of impulsivity-related disorders
HK1246679A1 (en) Treatment of filarial diseases
HK1243937A1 (en) Methods of treating diseases
SG11202005850VA (en) Methods of treatment of hypertrigl yceridemia
GB201412010D0 (en) Treatment of hypertransaminasemia
GB201512139D0 (en) Methods of treatment
AU2016904966A0 (en) Method of treatment
AU2016900743A0 (en) Methods of treatment
AU2016902980A0 (en) Method of Treatment
AU2015905220A0 (en) Methods of treatment
AU2016902594A0 (en) Method of Treatment
GB201511017D0 (en) Method of treatment