MX348439B - High viscosity diutan gums and methods of producing. - Google Patents
High viscosity diutan gums and methods of producing.Info
- Publication number
- MX348439B MX348439B MX2013013969A MX2013013969A MX348439B MX 348439 B MX348439 B MX 348439B MX 2013013969 A MX2013013969 A MX 2013013969A MX 2013013969 A MX2013013969 A MX 2013013969A MX 348439 B MX348439 B MX 348439B
- Authority
- MX
- Mexico
- Prior art keywords
- polysaccharide
- diutan
- production
- improved
- diutan polysaccharide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B11/00—Preparation of cellulose ethers
- C08B11/02—Alkyl or cycloalkyl ethers
- C08B11/04—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals
- C08B11/10—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals substituted with acid radicals
- C08B11/12—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals substituted with acid radicals substituted with carboxylic radicals, e.g. carboxymethylcellulose [CMC]
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/26—Cellulose ethers
- C08L1/28—Alkyl ethers
- C08L1/286—Alkyl ethers substituted with acid radicals, e.g. carboxymethyl cellulose [CMC]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
Abstract
The present invention describes the production of a diutan polysaccharide exhibiting increased viscosity properties as compared with previously produced polysaccharide of the same type of repeating units. Such an improved diutan polysaccharide is produced through the generation of a derivative of Sphingomonas sp. ATCC 53159 that harbors a multicopy broad-host-range plasmid into which genes for biosynthesis of diutan polysaccharide have been cloned. The plasmid provides the capability within the host Sphingomonas strain to produce multiple copies of genes for such polysaccharide synthesis. In such a manner, a method of not just increased production of the target diutan polysaccharide, but also production of a diutan polysaccharide of improved physical properties (of the aforementioned higher viscosity) thereof is provided. Such a diutan polysaccharide has proven particularly useful as a possible viscosifier in oilfield applications and within cement materials. The inventive methods of production of such an improved diutan polysaccharide, as well as the novel cloned genes required to produce the improved diutan within such a method, are also encompassed within this invention. Additionally, the novel engineered Sphingomonas strain including the needed DNA sequence is encompassed within this invention.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/264,262 US20070166371A1 (en) | 2005-11-01 | 2005-11-01 | Methods of producing films and capsules made from modified carboxymethylcellulose materials |
US11/264,260 US20070098779A1 (en) | 2005-11-01 | 2005-11-01 | Films and capsules made from modified carboxymethylcellulose materials |
PCT/US2006/042456 WO2007053612A2 (en) | 2005-11-01 | 2006-10-31 | High viscosity diutan gums and methods of producing |
Publications (1)
Publication Number | Publication Date |
---|---|
MX348439B true MX348439B (en) | 2017-06-13 |
Family
ID=38006458
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013013969A MX348439B (en) | 2005-11-01 | 2006-10-31 | High viscosity diutan gums and methods of producing. |
MX2008005874A MX2008005874A (en) | 2005-11-01 | 2006-10-31 | Films and capsules made from modified carboxymethycellulose materials and methods of making same. |
MX2008005643A MX2008005643A (en) | 2005-11-01 | 2006-10-31 | High viscosity diutan gums and methods of producing. |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2008005874A MX2008005874A (en) | 2005-11-01 | 2006-10-31 | Films and capsules made from modified carboxymethycellulose materials and methods of making same. |
MX2008005643A MX2008005643A (en) | 2005-11-01 | 2006-10-31 | High viscosity diutan gums and methods of producing. |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1954250A2 (en) |
JP (1) | JP5364377B2 (en) |
KR (2) | KR101372110B1 (en) |
CN (2) | CN103772520B (en) |
AP (2) | AP2008004489A0 (en) |
AU (2) | AU2006310988A1 (en) |
CA (1) | CA2628207A1 (en) |
EA (2) | EA015170B1 (en) |
MX (3) | MX348439B (en) |
WO (2) | WO2007053608A2 (en) |
ZA (1) | ZA200804213B (en) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110027838A1 (en) | 2009-07-31 | 2011-02-03 | Harding Nancy E | Sphingomonas Strains Producing Greatly Increased Yield Of PHB-Deficient Sphingan (Diutan) |
SI3095447T1 (en) | 2006-02-03 | 2022-02-28 | Opko Renal, Llc | Treating vitamin d insufficiency and deficiency with 25-hydroxyvitamin d2 and 25-hydroxyvitamin d3 |
US20080108114A1 (en) | 2006-06-15 | 2008-05-08 | Cox Donald J | Glucan preparations |
ES2670029T3 (en) | 2006-06-21 | 2018-05-29 | Opko Ireland Global Holdings, Ltd. | Therapy using vitamin D replenishment agent and vitamin D hormone replacement agent |
EP2148683A4 (en) | 2007-04-25 | 2012-09-12 | Proventiv Therapeutics Llc | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
JP5444212B2 (en) | 2007-04-25 | 2014-03-19 | シトクロマ インコーポレイテッド | Method for treating vitamin D deficiency and deficiency |
PL2148661T3 (en) | 2007-04-25 | 2013-07-31 | Cytochroma Inc | Oral controlled release compositions comprising vitamin d compound and waxy carrier |
US20080274182A1 (en) * | 2007-05-03 | 2008-11-06 | Regina Helena Alida Boekema | Tablet coatings made from modified carboxymethylcellulose materials |
CA2704262A1 (en) * | 2007-10-31 | 2009-05-07 | Paladin Labs Inc. | Ingestible film composition |
ES2593356T3 (en) | 2008-04-02 | 2016-12-07 | Opko Ireland Global Holdings, Ltd. | Useful methods, compositions, uses and kits for vitamin D deficiency and related disorders |
EP3636280A1 (en) | 2010-03-29 | 2020-04-15 | Opko Ireland Global Holdings, Ltd. | Methods and compositions for reducing parathyroid levels |
US9296939B2 (en) | 2010-05-05 | 2016-03-29 | Halliburton Energy Services, Inc. | Compositions for modifying rheological properties of cement systems |
US9296943B2 (en) | 2012-05-22 | 2016-03-29 | Schlumberger Technology Corporation | Subterranean treatment fluid composition and method of treatment |
KR20140072716A (en) * | 2012-12-05 | 2014-06-13 | 삼성정밀화학 주식회사 | Film having improved haze |
KR101847947B1 (en) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | Stabilized modified release vitamin d formulation |
KR102199595B1 (en) * | 2013-12-31 | 2021-01-07 | 롯데정밀화학 주식회사 | Aqueous composition for hard capsule and hard capsule prepared thereof |
KR102161001B1 (en) * | 2013-12-31 | 2020-09-29 | 롯데정밀화학 주식회사 | Aqueous composition for hard capsuleand hard capsule prepared thereof |
KR102199596B1 (en) * | 2013-12-31 | 2021-01-07 | 롯데정밀화학 주식회사 | Aqueous composition for hard capsule and hard capsule prepared thereof |
CN106687122B (en) | 2014-07-10 | 2020-11-10 | 百奥赛诺公司 | Combination of beta-glucan and an anti-cancer agent affecting the tumor microenvironment |
CN114681468A (en) | 2014-08-07 | 2022-07-01 | 欧普科爱尔兰环球控股有限公司 | Adjunctive therapy with 25-hydroxyvitamin D |
JP6887378B2 (en) | 2014-11-06 | 2021-06-16 | バイオセラ,インク. | Beta-glucan methods and compositions that affect the intratumoral microenvironment |
KR20230056790A (en) | 2016-03-28 | 2023-04-27 | 옵코 아일랜드 글로벌 홀딩스 리미티드 | Methods of vitamin d treatment |
WO2018156888A1 (en) | 2017-02-24 | 2018-08-30 | Biothera Pharmaceuticals, Inc. | Beta glucan immunopharmacodynamics |
CN106977618B (en) * | 2017-04-13 | 2022-07-01 | 张星昊 | Method for extracting diutan from diutan fermentation liquor |
KR102065953B1 (en) * | 2018-02-07 | 2020-02-11 | 충남대학교산학협력단 | Composition for the preparation of carboxymethylnanocellulose composite film, film and production thereof |
US11648197B2 (en) | 2018-06-28 | 2023-05-16 | Arx, Llc | Dispensing method for producing dissolvable unit dose film constructs |
CN111807785B (en) * | 2020-07-17 | 2022-02-15 | 中铁建工集团有限公司 | Large-volume self-compacting concrete and preparation method thereof |
CN112680435B (en) * | 2021-01-25 | 2022-03-25 | 中国石油大学(华东) | Preparation method of sphingosine gum lyase and enzymatic sphingosine gum |
Family Cites Families (15)
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US6696561B1 (en) * | 1909-07-09 | 2004-02-24 | Basf Aktiengesellschaft | Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport |
IL79165A0 (en) * | 1985-06-28 | 1986-09-30 | Merck & Co Inc | Heteropolysaccharide s-657 and its preparation |
US5175278A (en) * | 1985-06-28 | 1992-12-29 | Merck & Co., Inc. | Heteropolysaccharide S-657 |
US5366755A (en) * | 1989-02-10 | 1994-11-22 | Maritta Timonen | Foodstuffs containing novel degraded cellulose derivatives |
US5550189A (en) * | 1992-04-17 | 1996-08-27 | Kimberly-Clark Corporation | Modified polysaccharides having improved absorbent properties and process for the preparation thereof |
JPH09252775A (en) * | 1995-01-24 | 1997-09-30 | Shin Etsu Chem Co Ltd | Dna segments and method for increasing polysaccharide production |
US5985623A (en) * | 1995-01-24 | 1999-11-16 | Shin-Etsu Bio, Inc. | DNA segments and methods for increasing polysaccharide production |
CA2239864C (en) * | 1995-12-15 | 2008-04-15 | Monsanto Company | Methods for improved rheological control in cementitious systems |
US6103671A (en) * | 1997-11-20 | 2000-08-15 | Texas United Chemical Company Llc. | Glycol solution drilling system |
GB9924634D0 (en) * | 1999-10-19 | 1999-12-22 | Univ St Andrews | Enzyme |
US6627785B1 (en) * | 2000-02-29 | 2003-09-30 | Virginia Commwealth University | Wound dressings with protease-lowering activity |
US7439044B2 (en) * | 2003-03-21 | 2008-10-21 | Cp Kelco U.S., Inc. | High viscosity xanthan polymer preparations |
US7052540B2 (en) * | 2004-03-11 | 2006-05-30 | Eastman Chemical Company | Aqueous dispersions of carboxylated cellulose esters, and methods of making them |
US20060041961A1 (en) * | 2004-03-25 | 2006-02-23 | Abad Mark S | Genes and uses for pant improvement |
CN103087941B (en) * | 2005-02-04 | 2015-09-16 | Cp凯尔科美国公司 | Polysaccharide slime formers forms the target gene disappearance of bacterium |
-
2006
- 2006-10-31 CN CN201310209621.6A patent/CN103772520B/en active Active
- 2006-10-31 EA EA200801224A patent/EA015170B1/en unknown
- 2006-10-31 EA EA200801223A patent/EA200801223A1/en unknown
- 2006-10-31 AU AU2006310988A patent/AU2006310988A1/en not_active Abandoned
- 2006-10-31 MX MX2013013969A patent/MX348439B/en unknown
- 2006-10-31 AP AP2008004489A patent/AP2008004489A0/en unknown
- 2006-10-31 CA CA002628207A patent/CA2628207A1/en not_active Abandoned
- 2006-10-31 MX MX2008005874A patent/MX2008005874A/en not_active Application Discontinuation
- 2006-10-31 AP AP2008004491A patent/AP2878A/en active
- 2006-10-31 JP JP2008538967A patent/JP5364377B2/en active Active
- 2006-10-31 WO PCT/US2006/042452 patent/WO2007053608A2/en active Application Filing
- 2006-10-31 WO PCT/US2006/042456 patent/WO2007053612A2/en active Application Filing
- 2006-10-31 KR KR1020087013201A patent/KR101372110B1/en active IP Right Grant
- 2006-10-31 AU AU2006308904A patent/AU2006308904B9/en active Active
- 2006-10-31 KR KR1020087013118A patent/KR20080106160A/en not_active Application Discontinuation
- 2006-10-31 CN CN2006800488019A patent/CN101558165B/en active Active
- 2006-10-31 MX MX2008005643A patent/MX2008005643A/en active IP Right Grant
- 2006-10-31 EP EP06827160A patent/EP1954250A2/en not_active Withdrawn
-
2008
- 2008-05-15 ZA ZA2008/04213A patent/ZA200804213B/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2007053608A3 (en) | 2009-01-22 |
CA2628207A1 (en) | 2007-05-10 |
AP2008004491A0 (en) | 2008-06-30 |
KR20080106160A (en) | 2008-12-04 |
WO2007053612A2 (en) | 2007-05-10 |
AU2006310988A1 (en) | 2007-05-10 |
AP2878A (en) | 2014-03-31 |
MX2008005874A (en) | 2008-11-27 |
EA200801224A1 (en) | 2009-04-28 |
EP1954250A2 (en) | 2008-08-13 |
WO2007053612A3 (en) | 2007-12-06 |
AU2006308904A1 (en) | 2007-05-10 |
CN101558165B (en) | 2013-07-03 |
CN103772520A (en) | 2014-05-07 |
CN103772520B (en) | 2018-04-10 |
JP5364377B2 (en) | 2013-12-11 |
AU2006308904B2 (en) | 2012-12-06 |
AP2008004489A0 (en) | 2008-06-30 |
WO2007053608A2 (en) | 2007-05-10 |
EA200801223A1 (en) | 2009-06-30 |
KR101372110B1 (en) | 2014-03-14 |
EA015170B1 (en) | 2011-06-30 |
AU2006308904B9 (en) | 2013-01-10 |
JP2009515512A (en) | 2009-04-16 |
KR20090016655A (en) | 2009-02-17 |
MX2008005643A (en) | 2008-12-09 |
ZA200804213B (en) | 2022-03-30 |
CN101558165A (en) | 2009-10-14 |
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