HRP20010333B1 - New controlled release bead, a method of producing the same and multiple unit formulation comprising it - Google Patents

New controlled release bead, a method of producing the same and multiple unit formulation comprising it

Info

Publication number
HRP20010333B1
HRP20010333B1 HR20010333A HRP20010333A HRP20010333B1 HR P20010333 B1 HRP20010333 B1 HR P20010333B1 HR 20010333 A HR20010333 A HR 20010333A HR P20010333 A HRP20010333 A HR P20010333A HR P20010333 B1 HRP20010333 B1 HR P20010333B1
Authority
HR
Croatia
Prior art keywords
producing
same
controlled release
multiple unit
unit formulation
Prior art date
Application number
HR20010333A
Other languages
English (en)
Inventor
Torkel Gren
Anders Ringberg
Martin Wikberg
Randy J Wald
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20413266&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20010333(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/SE1999/001463 external-priority patent/WO2000012069A1/en
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Publication of HRP20010333A2 publication Critical patent/HRP20010333A2/hr
Publication of HRP20010333B1 publication Critical patent/HRP20010333B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HR20010333A 1998-11-11 2001-05-10 New controlled release bead, a method of producing the same and multiple unit formulation comprising it HRP20010333B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9803871A SE9803871D0 (sv) 1998-11-11 1998-11-11 Therapeutic method and formulation
PCT/SE1999/001463 WO2000012069A1 (en) 1998-08-27 1999-08-26 Therapeutic formulation for administering tolterodine with controlled release
PCT/SE1999/002052 WO2000027364A1 (en) 1998-11-11 1999-11-11 New controlled release bead, a method of producing the same and multiple unit formulation comprising it

Publications (2)

Publication Number Publication Date
HRP20010333A2 HRP20010333A2 (en) 2003-04-30
HRP20010333B1 true HRP20010333B1 (en) 2004-10-31

Family

ID=20413266

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20010333A HRP20010333B1 (en) 1998-11-11 2001-05-10 New controlled release bead, a method of producing the same and multiple unit formulation comprising it

Country Status (40)

Country Link
US (1) US6911217B1 (sh)
EP (1) EP1128819B1 (sh)
JP (1) JP3616011B2 (sh)
KR (1) KR100467384B1 (sh)
CN (1) CN1169522C (sh)
AP (1) AP1323A (sh)
AR (1) AR027815A1 (sh)
AT (1) ATE247458T1 (sh)
AU (1) AU762410B2 (sh)
BG (1) BG65149B1 (sh)
BR (1) BRPI9915142B8 (sh)
CA (1) CA2350061C (sh)
CZ (1) CZ299582B6 (sh)
DE (1) DE69910604T2 (sh)
DK (1) DK1128819T3 (sh)
EA (1) EA005074B1 (sh)
EE (1) EE05232B1 (sh)
ES (1) ES2204193T3 (sh)
GE (1) GEP20022833B (sh)
HK (1) HK1040917B (sh)
HR (1) HRP20010333B1 (sh)
HU (1) HU226582B1 (sh)
ID (1) ID30039A (sh)
IL (1) IL142809A0 (sh)
IS (1) IS2370B (sh)
MA (1) MA25325A1 (sh)
MY (1) MY122195A (sh)
NO (1) NO331399B1 (sh)
NZ (1) NZ511430A (sh)
OA (1) OA11673A (sh)
PL (1) PL195780B1 (sh)
PT (1) PT1128819E (sh)
RS (1) RS49891B (sh)
SE (1) SE9803871D0 (sh)
SI (1) SI1128819T1 (sh)
SK (1) SK284758B6 (sh)
TW (2) TWI267385B (sh)
UA (1) UA57165C2 (sh)
WO (1) WO2000027364A1 (sh)
ZA (1) ZA200103575B (sh)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU728395B2 (en) * 1996-07-19 2001-01-11 Gunnar Aberg S(-)-tolterodine in the treatment of urinary and gastrointestinal disorders
US8563522B2 (en) 1997-07-08 2013-10-22 The Iams Company Method of maintaining and/or attenuating a decline in quality of life
EP0957073A1 (en) 1998-05-12 1999-11-17 Schwarz Pharma Ag Novel derivatives of 3,3-diphenylpropylamines
SI1227806T1 (sl) * 1999-11-11 2005-12-31 Pfizer Health Ab Farmacevtska formulacija, ki vsebuje tolterodin in njena uporaba
BR0313714A (pt) * 2002-08-28 2005-06-28 Pharmacia Corp Composição oral de tolterodina lìquida
US8168170B2 (en) 2002-10-03 2012-05-01 The Procter And Gamble Company Compositions having an inner core and at least three surrounding layers
BRPI0406861A (pt) * 2003-01-22 2006-01-03 Pfizer Health Ab Utilização de agente antimuscarìnico
DE10315917A1 (de) * 2003-04-08 2004-11-18 Schwarz Pharma Ag Hochreine Basen von 3,3-Diphenylpropylaminmonoestern
WO2004112756A1 (en) 2003-06-26 2004-12-29 Isa Odidi Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
WO2005046663A1 (en) 2003-11-04 2005-05-26 Shire Laboratories, Inc. Compositions of quaternary ammonium containing bioavailability enhancers
EP1680110B1 (en) 2003-11-04 2011-01-05 Supernus Pharmaceuticals, Inc. Once daily dosage forms of trospium
US7785635B1 (en) 2003-12-19 2010-08-31 The Procter & Gamble Company Methods of use of probiotic lactobacilli for companion animals
US20050158294A1 (en) 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
US8877178B2 (en) 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
US8894991B2 (en) 2003-12-19 2014-11-25 The Iams Company Canine probiotic Lactobacilli
US20050152884A1 (en) 2003-12-19 2005-07-14 The Procter & Gamble Company Canine probiotic Bifidobacteria globosum
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
EP1629834A1 (en) † 2004-08-27 2006-03-01 KRKA, D.D., Novo Mesto Sustained release pharmaceutical composition of tolterodine
US20060194876A1 (en) * 2005-01-10 2006-08-31 Kovacs Laszlo Z Substantially pure tolterodine tartrate and process for preparing thereof
CA2607949C (en) 2005-05-31 2012-09-25 Thomas William-Maxwell Boileau Feline probiotic bifidobacteria
EP2261323A1 (en) 2005-05-31 2010-12-15 The Iams Company Feline probiotic lactobacilli
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
PL1981465T3 (pl) 2006-01-18 2016-03-31 Intec Pharma Ltd Metoda wytwarzania przyrządów do podawania środka przyjmowanego doustnie
SI3095447T1 (sl) 2006-02-03 2022-02-28 Opko Renal, Llc Zdravljenje pomanjkanja vitamina D s 25-hidroksivitaminom D2 in 25-hidroksivitaminom D3
KR100714058B1 (ko) * 2006-02-06 2007-05-02 한국유나이티드제약 주식회사 톨테로딘 엘-주석산염의 서방형 경구투여 조성물 및 이의 제조 방법
CA2642340A1 (en) * 2006-02-24 2007-08-30 Teva Pharmaceutical Industries Ltd. Metoprolol succinate e.r. tablets and methods for their preparation
BRPI0708848A2 (pt) * 2006-03-21 2011-06-21 Teva Pharma formulação de liberação controlada de tolterodina
EP1839649A1 (en) * 2006-03-31 2007-10-03 LEK Pharmaceuticals D.D. Coated formulations for tolterodine
EP2007360B1 (en) * 2006-04-03 2014-11-26 Isa Odidi Controlled release delivery device comprising an organosol coat
US20070248670A1 (en) * 2006-04-21 2007-10-25 Van Den Heuvel Dennie J M Tolterodine beads
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
WO2007131804A1 (en) 2006-05-17 2007-11-22 Synthon B.V. Tablet composition with a prolonged release of tamsulosin
JP5563296B2 (ja) 2006-06-21 2014-07-30 プロヴェンティヴ セラピュティックス リミテッド ライアビリティ カンパニー 二次性副甲状腺機能亢進症の治療及び予防方法
JP2008007458A (ja) * 2006-06-29 2008-01-17 Freunt Ind Co Ltd レイヤリング用核粒子とその製造方法
EA201300152A1 (ru) 2006-11-27 2013-07-30 Х. Лундбекк А/С Гетероариламидные производные
CA2673465A1 (en) 2007-02-01 2008-08-07 The Iams Company Method for decreasing inflammation and stress in a mammal
CA2683514C (en) 2007-04-25 2019-07-09 Proventiv Therapeutics, Llc Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease
CA2943032C (en) 2007-04-25 2019-05-07 Cytochroma Inc. Oral controlled release compositions comprising vitamin d compound and waxy carrier
CN101668532B (zh) 2007-04-25 2014-08-20 赛特克罗公司 治疗维生素d不足和缺乏、继发性甲状旁腺功能亢进症和维生素d-响应疾病的组合物及其相应的制药用途
US20090017111A1 (en) * 2007-07-03 2009-01-15 Van Den Heuvel Dennie J M Tolterodine bead
US8110226B2 (en) * 2007-07-20 2012-02-07 Mylan Pharmaceuticals Inc. Drug formulations having inert sealed cores
US8486452B2 (en) 2007-07-20 2013-07-16 Mylan Pharmaceuticals Inc. Stabilized tolterodine tartrate formulations
WO2009019599A2 (en) 2007-08-08 2009-02-12 Themis Laboratories Private Limited Extended release compositions comprising tolterodine
CA2696341C (en) 2007-08-13 2016-05-17 Abuse Deterrent Pharmaceutical Llc Abuse resistant drugs, method of use and method of making
US20090192228A1 (en) * 2008-01-28 2009-07-30 Actavis Group Ptc Ehf Controlled-Release Tolterodine Compositions and Methods
US20090214665A1 (en) * 2008-02-26 2009-08-27 Lai Felix S Controlled Release Muscarinic Receptor Antagonist Formulation
CA2629099A1 (en) * 2008-04-01 2009-10-01 Pharmascience Inc. Novel oral controlled release pharmaceutical formulations
CA2714996C (en) 2008-04-02 2020-04-07 Cytochroma Inc. Methods, compositions, uses, and kits useful for vitamin d deficiency and related disorders
WO2009140557A2 (en) * 2008-05-14 2009-11-19 Capricorn Pharma, Inc. Modified release tolterodine formulations
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
US8465770B2 (en) 2008-12-24 2013-06-18 Synthon Bv Low dose controlled release tablet
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
WO2011013082A1 (en) * 2009-07-31 2011-02-03 Ranbaxy Laboratories Limited Multi-layered, multiple unit pharmaceutical compositions
WO2011061616A2 (en) 2009-11-23 2011-05-26 Micro Labs Limited Extended release compositions containing tolterodine and process for preparing the same
WO2011095388A1 (en) 2010-02-04 2011-08-11 Synthon Bv Tolterodine bead
JO3112B1 (ar) 2010-03-29 2017-09-20 Ferring Bv تركيبة دوائية سريعة التحلل
NZ706991A (en) 2010-03-29 2016-08-26 Ferring Bv A fast dissolving pharmaceutical composition
WO2011123476A1 (en) 2010-03-29 2011-10-06 Cytochroma Inc. Methods and compositions for reducing parathyroid levels
EP2563123B1 (en) 2010-04-30 2018-04-25 Merck Sharp & Dohme Corp. Novel beta 3 adrenergic receptor agonists
US20120040008A1 (en) * 2010-08-11 2012-02-16 Ashish Chatterji Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
WO2012154770A1 (en) 2011-05-10 2012-11-15 Theravida, Inc. Combinations of tolterodine and salivary stimulants for the treatment of overactive bladder
GR1007628B (el) 2011-07-27 2012-06-29 Φαρματεν Αβεε, Φαρμακευτικο σκευασμα περιεχον εναν αντιμουσκαρινικο παραγοντα και μεθοδος για την παρασκευη αυτου
MX345674B (es) 2011-09-16 2017-02-10 Ferring Bv Composicion farmaceutica de disolucion rapida.
BR112014007753B1 (pt) * 2011-09-30 2021-07-06 Astellas Pharma Inc. composição farmacêutica granular, formulação e método para produção
WO2014009241A1 (en) 2012-07-12 2014-01-16 Ferring B.V. Diclofenac formulations
WO2014047477A2 (en) * 2012-09-20 2014-03-27 Sks Ocular, Llc Multilayer biodegradable microparticles for sustained release of therapeutic agents
TW201422254A (zh) * 2012-11-21 2014-06-16 Ferring Bv 用於速釋及延釋的組成物
US20150306170A1 (en) * 2012-11-21 2015-10-29 Ferring B.V. Composition for immediate and extended release
EP2968579B1 (en) * 2013-03-13 2020-04-15 Intervet International B.V. Stable bioactive substances and methods of making
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
US20140275150A1 (en) 2013-03-15 2014-09-18 Inspirion Delivery Technologies, Llc Abuse deterrent compositions and methods of use
AU2014246617A1 (en) 2013-12-23 2015-07-09 Sun Pharmaceutical Industries Limited Multi-layered, multiple unit pharmaceutical compositions
PE20170392A1 (es) 2014-08-07 2017-04-07 Opko Ireland Global Holdings Ltd Terapia adjuntiva con 25-hidroxi vitamina d
US10729685B2 (en) 2014-09-15 2020-08-04 Ohemo Life Sciences Inc. Orally administrable compositions and methods of deterring abuse by intranasal administration
CA3018328A1 (en) * 2014-10-31 2016-04-30 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
JP6924177B2 (ja) * 2016-02-23 2021-08-25 ニプロ株式会社 医薬組成物粒子とそれを含む口腔内崩壊製剤
CR20180510A (es) 2016-03-28 2019-05-15 Opko Ireland Global Holdings Ltd Método de tratamiento con vitamina d

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1144911B (it) * 1981-03-19 1986-10-29 Pharmatec Spa Composizione farmaceutica a rilascio controllato contenente ibuprofen
JPH07107450A (ja) 1993-10-08 1995-04-21 Hitachi Ltd 情報通信装置
JP3453186B2 (ja) 1994-04-14 2003-10-06 共和薬品工業株式会社 徐放性マイクロカプセルおよびその製造方法
SE9402422D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New beads for controlled release and a pharmaceutical preparation containing the same
US5645858A (en) * 1994-10-06 1997-07-08 Ortho Pharmaceutical Corporation Multilayered controlled release pharmaceutical dosage form
US5567441A (en) * 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
AU728395B2 (en) 1996-07-19 2001-01-11 Gunnar Aberg S(-)-tolterodine in the treatment of urinary and gastrointestinal disorders
US6312728B1 (en) * 1998-07-07 2001-11-06 Cascade Development, Inc. Sustained release pharmaceutical preparation

Also Published As

Publication number Publication date
BRPI9915142B1 (pt) 2015-08-25
MY122195A (en) 2006-03-31
EE200100254A (et) 2002-12-16
CA2350061A1 (en) 2000-05-18
JP3616011B2 (ja) 2005-02-02
BG65149B1 (bg) 2007-04-30
IL142809A0 (en) 2002-03-10
AP2001002166A0 (en) 2001-06-30
AU762410B2 (en) 2003-06-26
EP1128819B1 (en) 2003-08-20
HK1040917A1 (en) 2002-06-28
CZ20011627A3 (cs) 2001-10-17
EE05232B1 (et) 2009-12-15
KR20010075695A (ko) 2001-08-09
PL195780B1 (pl) 2007-10-31
NO20012314D0 (no) 2001-05-10
DE69910604T2 (de) 2004-06-24
YU33101A (sh) 2003-10-31
US6911217B1 (en) 2005-06-28
EA200100538A1 (ru) 2001-10-22
IS5936A (is) 2001-05-09
NO20012314L (no) 2001-07-09
EA005074B1 (ru) 2004-10-28
HK1040917B (zh) 2005-05-27
ZA200103575B (en) 2002-05-03
SE9803871D0 (sv) 1998-11-11
NZ511430A (en) 2003-05-30
AP1323A (en) 2004-11-05
CN1326339A (zh) 2001-12-12
SI1128819T1 (en) 2003-12-31
UA57165C2 (uk) 2003-06-16
JP2003517446A (ja) 2003-05-27
HRP20010333A2 (en) 2003-04-30
PT1128819E (pt) 2003-12-31
BG105582A (en) 2001-12-29
BRPI9915142B8 (pt) 2021-05-25
RS49891B (sr) 2008-08-07
AR027815A1 (es) 2003-04-16
AU1436600A (en) 2000-05-29
WO2000027364A1 (en) 2000-05-18
EP1128819A1 (en) 2001-09-05
TWI267385B (en) 2006-12-01
OA11673A (en) 2005-01-12
CA2350061C (en) 2005-05-17
NO331399B1 (no) 2011-12-19
TWI222879B (en) 2004-11-01
SK6252001A3 (en) 2002-01-07
PL348612A1 (en) 2002-06-03
HUP0105038A3 (en) 2006-07-28
BR9915142A (pt) 2001-08-07
CN1169522C (zh) 2004-10-06
ATE247458T1 (de) 2003-09-15
GEP20022833B (en) 2002-11-25
HUP0105038A2 (en) 2002-06-29
ID30039A (id) 2001-11-01
HU226582B1 (en) 2009-04-28
DK1128819T3 (da) 2003-12-01
IS2370B (is) 2008-06-15
SK284758B6 (sk) 2005-11-03
DE69910604D1 (de) 2003-09-25
KR100467384B1 (ko) 2005-01-24
MA25325A1 (fr) 2001-12-31
CZ299582B6 (cs) 2008-09-10
ES2204193T3 (es) 2004-04-16

Similar Documents

Publication Publication Date Title
HRP20010333B1 (en) New controlled release bead, a method of producing the same and multiple unit formulation comprising it
AU1943699A (en) Patterned coated articles and methods for producing the same
HK1031382A1 (en) Spiroazabicyclic heterocyclic compounds, a method for producing the same and use thereof
HK1044338A1 (en) 5-Pyridyl-1, 3-azole compounds, process for producing the same and use thereof
HUP0003200A3 (en) Method for making a relatively soft product, and the product itself
HUP0101192A3 (en) Cycloalkene derivatives, process for producing the same, and use
AU5855498A (en) Monoolefinic c5-mononitriles, method for the production and the use thereof
AU3031899A (en) Nanoparticles, method for producing nanoparticles and use of the same
HK1029114A1 (en) Thiodepsipeptides for combating endoparasites and a method for producing the same
AU7809198A (en) Electoluminescent device and method for producing the same
AU5398298A (en) Neutral-tasting microcapsules, method for their manufacturing and their use
ZA973433B (en) A sertindole-containing preparation and a method for producing the same.
HUP0004043A2 (en) Impregnated salts, a method for producing said salts, and the use of the same
AU5645598A (en) New benzoxazinedione derivatives, a method of producing them and the use thereof
AU2001288789A1 (en) Airbag and method for producing the same
AU6333199A (en) Webbing and method for producing the same
AU2002227966A1 (en) Coniosetin and derivatives thereof, method for producing the same and use thereof
IL138904A0 (en) Magnetic- abrasive powder, and method of producing the same
AU2796602A (en) Coniosetin and derivatives thereof, method for producing the same and use thereof
AU2002221904A1 (en) Ceiling and method for producing the same
AU3274899A (en) Acryronitrile-based compound, method for producing the same and pest controllingagent comprising the same
AU3855299A (en) Nanostructured film-type carbon material and method for producing the same
HUP0303553A3 (en) Plaster which contains steroids, and a method for the production and use thereof
HUP0002895A3 (en) 3-azabicyclo[3.1.0]hexanes, method for producing the same, and their use
AU9004598A (en) Ampule and method for manufacturing the same

Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20181030

Year of fee payment: 20

PB20 Patent expired after termination of 20 years

Effective date: 20191111