WO2011071343A3 - 라만 활성분자가 나노입자 이합체의 접합부에 위치한 이합체 코어쉘 나노 입자, 이의 용도 및 이의 제조방법 - Google Patents

라만 활성분자가 나노입자 이합체의 접합부에 위치한 이합체 코어쉘 나노 입자, 이의 용도 및 이의 제조방법 Download PDF

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WO2011071343A3
WO2011071343A3 PCT/KR2010/008862 KR2010008862W WO2011071343A3 WO 2011071343 A3 WO2011071343 A3 WO 2011071343A3 KR 2010008862 W KR2010008862 W KR 2010008862W WO 2011071343 A3 WO2011071343 A3 WO 2011071343A3
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heterodimer
nanoparticle
core
raman
binding portion
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PCT/KR2010/008862
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English (en)
French (fr)
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WO2011071343A2 (ko
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서영덕
남좌민
임동권
전기석
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한국화학연구원
서울대학교 산학협력단
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Priority to US13/514,920 priority Critical patent/US20130029360A1/en
Application filed by 한국화학연구원, 서울대학교 산학협력단 filed Critical 한국화학연구원
Priority to CN201080060485.3A priority patent/CN102811943B/zh
Priority to JP2012543027A priority patent/JP5701896B2/ja
Priority to RU2012129158/10A priority patent/RU2542386C2/ru
Priority to BR112012013999-1A priority patent/BR112012013999B1/pt
Priority to CA2783788A priority patent/CA2783788C/en
Priority to AU2010328768A priority patent/AU2010328768B2/en
Priority to EP10836238.5A priority patent/EP2511231B1/en
Publication of WO2011071343A2 publication Critical patent/WO2011071343A2/ko
Publication of WO2011071343A3 publication Critical patent/WO2011071343A3/ko
Priority to IL220294A priority patent/IL220294A/en
Priority to US15/069,063 priority patent/US20160266104A1/en
Priority to US16/906,093 priority patent/US20200385790A1/en

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    • G—PHYSICS
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60—Detection means characterised by use of a special device
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Abstract

본 발명은 라만 활성분자가 나노입자 이합체의 접합부에 위치한 구조의 나노입자 이합체에 관한 것으로, 보다 구체적으로는 표면에 올리고뉴클레오티드로 결합된 금 또는 은 코어(core) 및 상기 코어를 둘러싼 금 또는 은 쉘(shell)로 이루어진 코어-쉘 나노 입자로 이루어진 나노입자 이합체에 관한 것이다. 또한, 본 발명은 상기 코어-쉘 나노입자 이합체와 이의 제조방법, 및 용도에 관한 것이다.
PCT/KR2010/008862 2008-05-07 2010-12-10 라만 활성분자가 나노입자 이합체의 접합부에 위치한 이합체 코어쉘 나노 입자, 이의 용도 및 이의 제조방법 WO2011071343A2 (ko)

Priority Applications (11)

Application Number Priority Date Filing Date Title
CA2783788A CA2783788C (en) 2009-12-11 2010-12-10 Dimeric core-shell nanostructure labeled with raman active molecule localized at interparticle junction, use thereof, and method for preparing the same
CN201080060485.3A CN102811943B (zh) 2009-12-11 2010-12-10 以位于粒子间的结合部的拉曼活性分子标记的二聚体核壳纳米结构、其用途及制备方法
JP2012543027A JP5701896B2 (ja) 2009-12-11 2010-12-10 ラマン活性分子がナノ粒子二量体の接合部に位置する二量体コア−シェルナノ粒子、その用途およびその製造方法
RU2012129158/10A RU2542386C2 (ru) 2009-12-11 2010-12-10 Димерная окклюдантная наноструктура, меченная молекулой, активной в отношении рамановского рассеяния, локализованной в межчастичном соединении, ее использование и способ ее получения
BR112012013999-1A BR112012013999B1 (pt) 2009-12-11 2010-12-10 nanoestrutura dimérica de casca-núcleo marcada com molécula raman ativa localizada na junção de interpartículas e método para preparação do mesmo e para a detecção de um analito
US13/514,920 US20130029360A1 (en) 2009-12-11 2010-12-10 Dimeric core-shell nanostructure labeled with raman active molecule localized at interparticle junction, use thereof, and method for preparing the same
AU2010328768A AU2010328768B2 (en) 2009-12-11 2010-12-10 A dimeric core-shell nanostructure labeled with a raman active molecule localized at an interparticle junction, use thereof, and method for preparing the same
EP10836238.5A EP2511231B1 (en) 2009-12-11 2010-12-10 Heterodimer core-shell nanoparticle in which raman-active molecules are located at a binding portion of a nanoparticle heterodimer, use thereof, and method for preparing same
IL220294A IL220294A (en) 2009-12-11 2012-06-10 Nano structure with a dimeric nucleus shell labeled with a raman active molecule is located at the intersection of particles, its use and method for making it
US15/069,063 US20160266104A1 (en) 2008-05-07 2016-03-14 Heterodimeric core-shell nanoparticle in which raman-active molecules are located at a binding portion of a nanoparticle heterodimer, use thereof, and method for preparing same
US16/906,093 US20200385790A1 (en) 2008-05-07 2020-06-19 Heterodimeric core-shell nanoparticle in which raman-active molecules are located at a binding portion of a nanoparticle heterodimer, use thereof, and method for preparing same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2009-0123017 2009-12-11
KR20090123017 2009-12-11

Related Child Applications (4)

Application Number Title Priority Date Filing Date
PCT/KR2009/002399 Continuation-In-Part WO2009136741A1 (en) 2008-05-07 2009-05-07 Novel au / ag core-shell composite useful for biosensor
US12/991,537 Continuation-In-Part US20110124008A1 (en) 2008-05-07 2009-05-07 NOVEL Au/Ag CORE-SHELL COMPOSITE USEFUL FOR BIOSENSOR
US13/514,920 A-371-Of-International US20130029360A1 (en) 2009-12-11 2010-12-10 Dimeric core-shell nanostructure labeled with raman active molecule localized at interparticle junction, use thereof, and method for preparing the same
US15/069,063 Continuation-In-Part US20160266104A1 (en) 2008-05-07 2016-03-14 Heterodimeric core-shell nanoparticle in which raman-active molecules are located at a binding portion of a nanoparticle heterodimer, use thereof, and method for preparing same

Publications (2)

Publication Number Publication Date
WO2011071343A2 WO2011071343A2 (ko) 2011-06-16
WO2011071343A3 true WO2011071343A3 (ko) 2011-10-13

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PCT/KR2010/008862 WO2011071343A2 (ko) 2008-05-07 2010-12-10 라만 활성분자가 나노입자 이합체의 접합부에 위치한 이합체 코어쉘 나노 입자, 이의 용도 및 이의 제조방법

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US (1) US20130029360A1 (ko)
EP (1) EP2511231B1 (ko)
JP (1) JP5701896B2 (ko)
KR (1) KR101247610B1 (ko)
CN (1) CN102811943B (ko)
AU (1) AU2010328768B2 (ko)
BR (1) BR112012013999B1 (ko)
CA (1) CA2783788C (ko)
IL (1) IL220294A (ko)
RU (1) RU2542386C2 (ko)
WO (1) WO2011071343A2 (ko)

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