WO2009001019A3 - Nanocapsules a coeur lipidique liquide chargees en actifs(s) hydrosoluble(s) ou hydrodispersible(s) - Google Patents

Nanocapsules a coeur lipidique liquide chargees en actifs(s) hydrosoluble(s) ou hydrodispersible(s) Download PDF

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Publication number
WO2009001019A3
WO2009001019A3 PCT/FR2008/051042 FR2008051042W WO2009001019A3 WO 2009001019 A3 WO2009001019 A3 WO 2009001019A3 FR 2008051042 W FR2008051042 W FR 2008051042W WO 2009001019 A3 WO2009001019 A3 WO 2009001019A3
Authority
WO
WIPO (PCT)
Prior art keywords
water
nanocapsules
soluble
ingredient
core loaded
Prior art date
Application number
PCT/FR2008/051042
Other languages
English (en)
Other versions
WO2009001019A2 (fr
Inventor
Patrick Saulnier
Jean-Pierre Benoit
Nicolas Anton
Original Assignee
Univ Angers
Patrick Saulnier
Jean-Pierre Benoit
Nicolas Anton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Angers, Patrick Saulnier, Jean-Pierre Benoit, Nicolas Anton filed Critical Univ Angers
Priority to EP08805977A priority Critical patent/EP2167053A2/fr
Priority to US12/663,937 priority patent/US9333180B2/en
Priority to CA2690471A priority patent/CA2690471A1/fr
Publication of WO2009001019A2 publication Critical patent/WO2009001019A2/fr
Publication of WO2009001019A3 publication Critical patent/WO2009001019A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention concerne des nanocapsules à cœur lipidique liquide et écorce lipidique solide et chargées au sein de leur cœur lipidique en au moins un actif hydrosoluble ou hydrodispersible, ledit actif y étant présent sous la forme d'un système micellaire inverse.
PCT/FR2008/051042 2007-06-11 2008-06-11 Nanocapsules a coeur lipidique liquide chargees en actifs(s) hydrosoluble(s) ou hydrodispersible(s) WO2009001019A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP08805977A EP2167053A2 (fr) 2007-06-11 2008-06-11 Nanocapsules a coeur lipidique liquide chargees en actif(s) hydrosoluble(s) ou hydrodispersible(s)
US12/663,937 US9333180B2 (en) 2007-06-11 2008-06-11 Nanocapsules with a liquid lipid core charged with water-soluble or water-dispersible active agents
CA2690471A CA2690471A1 (fr) 2007-06-11 2008-06-11 Nanocapsules a coeur lipidique liquide chargees en actif(s) hydrosoluble(s) ou hydrodispersible(s)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0755652 2007-06-11
FR0755652A FR2916973B1 (fr) 2007-06-11 2007-06-11 Nanocapsules a coeur lipidique chargees en actif(s) hydrosoluble(s) ou hydrodispersible(s)

Publications (2)

Publication Number Publication Date
WO2009001019A2 WO2009001019A2 (fr) 2008-12-31
WO2009001019A3 true WO2009001019A3 (fr) 2009-03-26

Family

ID=39046733

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2008/051042 WO2009001019A2 (fr) 2007-06-11 2008-06-11 Nanocapsules a coeur lipidique liquide chargees en actifs(s) hydrosoluble(s) ou hydrodispersible(s)

Country Status (5)

Country Link
US (1) US9333180B2 (fr)
EP (1) EP2167053A2 (fr)
CA (1) CA2690471A1 (fr)
FR (1) FR2916973B1 (fr)
WO (1) WO2009001019A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9393315B2 (en) 2011-06-08 2016-07-19 Nitto Denko Corporation Compounds for targeting drug delivery and enhancing siRNA activity
FR2939699B1 (fr) 2008-12-12 2011-05-06 Univ Angers Procede de preparation de nanoparticules lipidiques
FR2943544B1 (fr) 2009-03-31 2012-04-20 Univ Angers Procede de preparation de capsules lipidiques fonctionnalisees.
US10196637B2 (en) 2011-06-08 2019-02-05 Nitto Denko Corporation Retinoid-lipid drug carrier
FR3017294B1 (fr) 2014-02-07 2021-10-01 Atlangram Nanoparticules lipidiques comprenant un antibiotique et leurs utilisations en therapie
CN108323159A (zh) * 2015-07-09 2018-07-24 麦迪西斯医药公司 在生物相容性反胶束系统内原位制备氰基桥接的金属纳米粒子
MX2018010043A (es) 2016-03-07 2018-11-09 Cryovac Inc Pelicula de facil apertura para empaque de recubrimiento al vacio.
GB201721832D0 (en) 2017-12-22 2018-02-07 Waterford Institute Of Tech Ocular drug delivery
WO2020021052A2 (fr) 2018-07-27 2020-01-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Utilisation d'alcools terpéniques acycliques pour améliorer l'activité antimicrobienne de la colistine
EP3679928A1 (fr) 2019-01-08 2020-07-15 Atlangram Composition pharmaceutique de type gel pour traiter/prevenir une infection
BR112021025859A2 (pt) * 2019-06-21 2022-03-03 Univ Catholique Louvain Nanocápsulas de lipídeo carregadas com miméticos de incretina
US12090151B1 (en) 2023-05-12 2024-09-17 Michael Guarnieri Injectable sustained release buprenorphine formulation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2805761A1 (fr) * 2000-03-02 2001-09-07 Mainelab Nanocapsules lipidiques, procede de preparation et utilisation comme medicament

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5961970A (en) * 1993-10-29 1999-10-05 Pharmos Corporation Submicron emulsions as vaccine adjuvants
FR2840532B1 (fr) * 2002-06-11 2005-05-06 Ethypharm Sa Nanocapsules lipidiques furtives, procede de preparation et utilisation comme vecteur de principes(s) actif(s)
EP1955695A1 (fr) * 2007-02-06 2008-08-13 Institut National De La Sante Et De La Recherche Medicale (Inserm) Nanocapsules de complexes lipophiles d'acides nucléiques
FR2916974B1 (fr) * 2007-06-11 2010-11-26 Univ Angers Procede de preparation de nanoparticules lipidiques

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2805761A1 (fr) * 2000-03-02 2001-09-07 Mainelab Nanocapsules lipidiques, procede de preparation et utilisation comme medicament

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2167053A2 *

Also Published As

Publication number Publication date
CA2690471A1 (fr) 2008-12-31
US20100266676A1 (en) 2010-10-21
US9333180B2 (en) 2016-05-10
FR2916973B1 (fr) 2010-02-26
FR2916973A1 (fr) 2008-12-12
EP2167053A2 (fr) 2010-03-31
WO2009001019A2 (fr) 2008-12-31

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