WO2009031642A1 - 医薬組成物 - Google Patents

医薬組成物 Download PDF

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Publication number
WO2009031642A1
WO2009031642A1 PCT/JP2008/066056 JP2008066056W WO2009031642A1 WO 2009031642 A1 WO2009031642 A1 WO 2009031642A1 JP 2008066056 W JP2008066056 W JP 2008066056W WO 2009031642 A1 WO2009031642 A1 WO 2009031642A1
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical composition
mass
general formula
halogen
alcohol
Prior art date
Application number
PCT/JP2008/066056
Other languages
English (en)
French (fr)
Inventor
Takaaki Masuda
Naoko Kobayashi
Hideaki Sasagawa
Original Assignee
Pola Pharma Inc.
Nihon Nohyaku Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pola Pharma Inc., Nihon Nohyaku Co., Ltd. filed Critical Pola Pharma Inc.
Priority to EP08829061.4A priority Critical patent/EP2191826B1/en
Priority to CN2008801059132A priority patent/CN101808637B/zh
Priority to US12/676,346 priority patent/US20100204293A1/en
Priority to JP2009531290A priority patent/JP5529539B2/ja
Publication of WO2009031642A1 publication Critical patent/WO2009031642A1/ja
Priority to US13/603,220 priority patent/US8513296B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

一般式（１）で示される化合物と、アルコールを５０～９５質量％と、水及び／又はアニオン性界面活性剤を０．１～３５質量％と、を含有することを特徴とする、抗真菌用外用剤。Ｘ＝ハロゲンまたはＨ　一般式（１）
PCT/JP2008/066056 2007-09-05 2008-09-05 医薬組成物 WO2009031642A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP08829061.4A EP2191826B1 (en) 2007-09-05 2008-09-05 Pharmaceutical composition
CN2008801059132A CN101808637B (zh) 2007-09-05 2008-09-05 医药组合物
US12/676,346 US20100204293A1 (en) 2007-09-05 2008-09-05 Pharmaceutical composition
JP2009531290A JP5529539B2 (ja) 2007-09-05 2008-09-05 医薬組成物
US13/603,220 US8513296B2 (en) 2007-09-05 2012-09-04 Pharmaceutical composition

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007229619 2007-09-05
JP2007-229619 2007-09-05

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US12/676,346 A-371-Of-International US20100204293A1 (en) 2007-09-05 2008-09-05 Pharmaceutical composition
US13/603,220 Continuation US8513296B2 (en) 2007-09-05 2012-09-04 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
WO2009031642A1 true WO2009031642A1 (ja) 2009-03-12

Family

ID=40428954

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/066056 WO2009031642A1 (ja) 2007-09-05 2008-09-05 医薬組成物

Country Status (6)

Country Link
US (2) US20100204293A1 (ja)
EP (1) EP2191826B1 (ja)
JP (1) JP5529539B2 (ja)
KR (1) KR20100075475A (ja)
CN (1) CN101808637B (ja)
WO (1) WO2009031642A1 (ja)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120149745A1 (en) * 2009-08-25 2012-06-14 Nihon Nohyaku Co., Ltd. Antimycotic pharmaceutical composition
JP2012523410A (ja) * 2009-04-09 2012-10-04 株式会社ポーラファルマ 抗真菌医薬組成物
JP2013528157A (ja) * 2010-06-11 2013-07-08 株式会社ポーラファルマ 抗真菌医薬組成物
JP2013545819A (ja) * 2010-12-16 2013-12-26 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 非経口投与のためのアゾール医薬製剤ならびにその調製方法およびアゾール化合物に対して感受性の疾患の処置としてのその使用方法
WO2014041846A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Use of surface free energy for differential evaluation of crystal, crystal evaluated on basis of surface free energy as index, and phrmaceutical composition prepared by containing the crystal
WO2014041708A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Crystal having crystal habits and pharmaceutical composition obtained by processing the crystal
WO2014042043A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Pharmaceutical composition containing luliconazole
WO2014042231A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Crystal and pharmaceutical preparation containing the same crystal
WO2014041825A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Amide derivative and use of the same as stability index of a luliconazole pharmaceutical formulation
WO2014136282A1 (en) 2013-03-08 2014-09-12 Pola Pharma Inc. Crystalline form having specific crystal habit and pharmaceutical composition|containing this crystalline form as active ingredient
JP2015027984A (ja) * 2013-06-24 2015-02-12 株式会社ポーラファルマ 結晶及び該結晶を含有してなる医薬製剤
WO2015033612A1 (en) 2013-09-06 2015-03-12 Pola Pharma Inc. Crystal having specific crystal habit and pharmaceutical composition containing the crystal as active ingredient
US8980931B1 (en) 2013-12-12 2015-03-17 Pola Pharma Inc. Method of evaluating pharmaceutical preparation containing luliconazole and index substance
JP2015063566A (ja) * 2015-01-06 2015-04-09 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物
JP2018016648A (ja) * 2012-05-11 2018-02-01 ロート製薬株式会社 ルリコナゾール含有外用医薬組成物
US10130610B2 (en) 2009-04-09 2018-11-20 Pola Pharma Inc. Antimycotic pharmaceutical composition
US10548890B2 (en) 2011-04-28 2020-02-04 Platform Brightworks Two, Ltd. Parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007102243A1 (ja) * 2006-03-08 2007-09-13 Nihon Nohyaku Co., Ltd. 外用の医薬組成物
EP2025337B1 (en) * 2006-03-08 2014-09-10 Nihon Nohyaku Co., Ltd. Pharmaceutical composition for external use
RU2423128C2 (ru) * 2006-03-08 2011-07-10 Нихон Нохияку Ко., Лтд. Фармацевтическая композиция для наружного применения
WO2009031642A1 (ja) 2007-09-05 2009-03-12 Pola Pharma Inc. 医薬組成物
EP2191828B1 (en) * 2007-09-05 2016-08-10 Pola Pharma Inc. Antifungal pharmaceutical composition
WO2009031643A1 (ja) 2007-09-05 2009-03-12 Pola Pharma Inc. 抗真菌組成物
JP5654497B2 (ja) * 2009-02-13 2015-01-14 トピカ ファーマシューティカルズ，インコーポレイテッド 抗真菌製剤
EA201171219A1 (ru) * 2009-04-07 2012-05-30 Холланд Калорз Н.В. Концентрат добавки для полимеров
US9480746B2 (en) * 2014-04-21 2016-11-01 Pola Pharma Inc. Resin container filled with antifungal pharmaceutical composition
CN107865825B (zh) * 2016-09-28 2022-05-20 四川海思科制药有限公司 一种卢立康唑外用喷雾剂药物组合物及其制备方法
US10898470B1 (en) 2019-08-13 2021-01-26 Sato Pharmaceutical Co., Ltd. Pharmaceutical composition containing antifungal agent as active ingredient

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JP2012523410A (ja) * 2009-04-09 2012-10-04 株式会社ポーラファルマ 抗真菌医薬組成物
US10130610B2 (en) 2009-04-09 2018-11-20 Pola Pharma Inc. Antimycotic pharmaceutical composition
US9050271B2 (en) 2009-04-09 2015-06-09 Pola Pharma Inc. Antimycotic pharmaceutical composition
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EP2191826A1 (en) 2010-06-02
US20100204293A1 (en) 2010-08-12
JPWO2009031642A1 (ja) 2010-12-16
CN101808637B (zh) 2013-07-24
JP5529539B2 (ja) 2014-06-25
EP2191826B1 (en) 2017-03-08
CN101808637A (zh) 2010-08-18

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