UY24277A1 - Sistema transcorneal de liberacion de medicamentos - Google Patents

Sistema transcorneal de liberacion de medicamentos

Info

Publication number
UY24277A1
UY24277A1 UY24277A UY24277A UY24277A1 UY 24277 A1 UY24277 A1 UY 24277A1 UY 24277 A UY24277 A UY 24277A UY 24277 A UY24277 A UY 24277A UY 24277 A1 UY24277 A1 UY 24277A1
Authority
UY
Uruguay
Prior art keywords
micro
reservoir
patient
transcorneal
tines
Prior art date
Application number
UY24277A
Other languages
English (en)
Inventor
Joachim Eicher
Bernd Zierenberg
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of UY24277A1 publication Critical patent/UY24277A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen

Abstract

Sistema transcorneal para la administración transcorneal activamente controlada de un medicamento a un paciente, que comprende: un dispositivo para la sustancia activa; un dispositivo provisto de microhojas adaptado en el uso para penetrar el estrato córneo del paciente y conectado con el depósito por medio de una conexión transmisora de líquido que permite el pasaje de la sustancia activa desde el depósito hacia el paciente a lo largo de las microhojas; un medio para la descarga activamente controlada del líquido que contiene la droga desde el depósito hacia la piel del paciente a través de las microhojas, en el cual el medio para la descarga activamente controlada del líquido que contiene la droga comprende una bomba integrada y controles electrónicos integrados. Se incluye un sistema según lo descrito provisto de una pluralidad de micropúas (en cambio de microhojas), y que además puede comprender microválvulas situadas entre el depósito y las aberturas capilares de las micropúas, donde cada una de las micropúas tiene una abertura de salida en su extremo y un capilar por dentro, que conecta la abertura de salida en el extremo de la micropúa con el depósito.
UY24277A 1995-07-14 1996-07-11 Sistema transcorneal de liberacion de medicamentos UY24277A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19525607A DE19525607A1 (de) 1995-07-14 1995-07-14 Transcorneales Arzneimittelfreigabesystem

Publications (1)

Publication Number Publication Date
UY24277A1 true UY24277A1 (es) 1996-12-31

Family

ID=7766771

Family Applications (1)

Application Number Title Priority Date Filing Date
UY24277A UY24277A1 (es) 1995-07-14 1996-07-11 Sistema transcorneal de liberacion de medicamentos

Country Status (34)

Country Link
US (1) US6132755A (es)
EP (1) EP0840634B1 (es)
JP (1) JPH11509123A (es)
KR (1) KR100430703B1 (es)
CN (1) CN1183979C (es)
AR (1) AR004499A1 (es)
AT (1) ATE207769T1 (es)
AU (1) AU722943B2 (es)
BG (1) BG63142B1 (es)
BR (1) BR9609796A (es)
CA (1) CA2226718C (es)
CO (1) CO4700491A1 (es)
CZ (1) CZ290458B6 (es)
DE (2) DE19525607A1 (es)
DK (1) DK0840634T3 (es)
EE (1) EE04006B1 (es)
ES (1) ES2163035T3 (es)
HK (1) HK1010844A1 (es)
HU (1) HU222342B1 (es)
IL (1) IL122907A0 (es)
MX (1) MX9800401A (es)
NO (1) NO316313B1 (es)
NZ (1) NZ313984A (es)
PL (1) PL181658B1 (es)
PT (1) PT840634E (es)
RO (1) RO118738B1 (es)
RU (1) RU2209640C2 (es)
SK (1) SK284358B6 (es)
TR (1) TR199800048T1 (es)
TW (1) TW375528B (es)
UA (1) UA62918C2 (es)
UY (1) UY24277A1 (es)
WO (1) WO1997003718A1 (es)
ZA (1) ZA965931B (es)

Families Citing this family (287)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3399197A (en) * 1996-06-18 1998-01-07 Alza Corporation Device for enhancing transdermal agent delivery or sampling
US6746688B1 (en) * 1996-10-13 2004-06-08 Neuroderm Ltd. Apparatus for the transdermal treatment of Parkinson's disease
DE69720057T2 (de) * 1996-12-20 2003-09-25 Alza Corp Vorrichtung und verfahren zur erhöhung des transdermalen wirkstoffeflusses
JP3879785B2 (ja) * 1997-05-20 2007-02-14 日東電工株式会社 キラーt細胞賦活剤
US6918901B1 (en) 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
EP1037687B8 (en) * 1997-12-11 2008-10-22 Alza Corporation Device for enhancing transdermal agent flux
ATE302041T1 (de) * 1997-12-11 2005-09-15 Alza Corp Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
US7344499B1 (en) 1998-06-10 2008-03-18 Georgia Tech Research Corporation Microneedle device for extraction and sensing of bodily fluids
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
WO1999064580A1 (en) * 1998-06-10 1999-12-16 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
GB9815819D0 (en) * 1998-07-22 1998-09-16 Secr Defence Transferring materials into cells and a microneedle array
GB9815820D0 (en) * 1998-07-22 1998-09-16 Secr Defence Improvements relating to micro-machining
ATE280615T1 (de) * 1998-08-31 2004-11-15 Johnson & Johnson Consumer Elektrotransportvorrichtung mit klingen
AU6151599A (en) * 1998-09-18 2000-04-10 University Of Utah Research Foundation Surface micromachined microneedles
US7048723B1 (en) * 1998-09-18 2006-05-23 The University Of Utah Research Foundation Surface micromachined microneedles
WO2000035530A1 (en) * 1998-12-18 2000-06-22 Minimed Inc. Insertion sets with micro-piercing members for use with medical devices and methods of using the same
ATE290902T1 (de) 1999-04-16 2005-04-15 Johnson & Johnson Consumer Vorrichtung zur iontophoretischen verabreichung von medikamenten mit internen sensoren
EP1187653B1 (en) * 1999-06-04 2010-03-31 Georgia Tech Research Corporation Devices for enhanced microneedle penetration of biological barriers
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6312612B1 (en) 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6379324B1 (en) 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
AU6076200A (en) 1999-07-08 2001-01-30 Johnson & Johnson Consumer Companies, Inc. Exothermic bandage
US6890553B1 (en) 1999-07-08 2005-05-10 Johnson & Johnson Consumer Companies, Inc. Exothermic topical delivery device
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US7133717B2 (en) 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US6623457B1 (en) * 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US6835184B1 (en) * 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
WO2001041864A1 (en) * 1999-12-10 2001-06-14 Alza Corporation Skin treatment apparatus for sustained transdermal drug delivery
WO2001041863A1 (en) 1999-12-10 2001-06-14 Alza Corporation Device and method for enhancing microprotrusion skin piercing
US6622035B1 (en) 2000-01-21 2003-09-16 Instrumentarium Corp. Electrode for measurement of weak bioelectrical signals
EP1164928B1 (en) * 2000-01-21 2005-06-01 Instrumentarium Corporation Method of fabricating a medical electrode
IL134997A0 (en) * 2000-03-09 2001-05-20 Yehoshua Yeshurun Health care system based on micro device
WO2001066065A2 (en) * 2000-03-09 2001-09-13 Nanopass Ltd. Systems and methods for fluid transport through dermal barriers
US7404815B2 (en) 2000-05-01 2008-07-29 Lifescan, Inc. Tissue ablation by shear force for sampling biological fluids and delivering active agents
US6629949B1 (en) 2000-05-08 2003-10-07 Sterling Medivations, Inc. Micro infusion drug delivery device
US6659982B2 (en) 2000-05-08 2003-12-09 Sterling Medivations, Inc. Micro infusion drug delivery device
US6595947B1 (en) 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
US6565532B1 (en) 2000-07-12 2003-05-20 The Procter & Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
US6589202B1 (en) 2000-06-29 2003-07-08 Becton Dickinson And Company Method and apparatus for transdermally sampling or administering a substance to a patient
US6656147B1 (en) * 2000-07-17 2003-12-02 Becton, Dickinson And Company Method and delivery device for the transdermal administration of a substance
GB0017999D0 (en) * 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
US6533949B1 (en) 2000-08-28 2003-03-18 Nanopass Ltd. Microneedle structure and production method therefor
DE60129585T2 (de) 2000-09-08 2008-04-17 Alza Corp., Mountain View Transdermale vorrichtung
JP2002085561A (ja) * 2000-09-14 2002-03-26 Terumo Corp 液体注入針
AU2002210881A1 (en) * 2000-10-12 2002-04-22 Ink Jet Technology Ltd. Transdermal method
PL360998A1 (en) 2000-10-13 2004-09-20 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
IL155389A0 (en) 2000-10-13 2003-11-23 Alza Corportion Microprotrusion member retainer for impact applicator
RU2277390C2 (ru) 2000-10-13 2006-06-10 Алза Корпорейшн Аппликатор для силового воздействия комплектом микроножей
US7131987B2 (en) * 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
US6821281B2 (en) 2000-10-16 2004-11-23 The Procter & Gamble Company Microstructures for treating and conditioning skin
US7828827B2 (en) * 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
MXPA03003815A (es) 2000-10-26 2004-08-12 Johnson & Johnson Dispositivos de suministro transdermico de farmaco que tienen microrresaltos recubiertos.
US6638246B1 (en) 2000-11-28 2003-10-28 Scimed Life Systems, Inc. Medical device for delivery of a biologically active material to a lumen
WO2002064193A2 (en) 2000-12-14 2002-08-22 Georgia Tech Research Corporation Microneedle devices and production thereof
WO2002050584A2 (en) 2000-12-21 2002-06-27 Biovalve Technologies, Inc. Microneedle array systems
DE10065168A1 (de) * 2000-12-23 2002-07-11 Lohmann Therapie Syst Lts Nadelpflaster mit vermindertem Infektionsrisiko
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
US6855372B2 (en) 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
IL158480A0 (en) 2001-04-20 2004-05-12 Alza Corp Microprojection array having a beneficial agent containing coating
EP3251722B1 (en) 2001-04-20 2020-06-17 ALZA Corporation Microprojection array having a beneficial agent containing coating and method of forming the coating thereon
US6591124B2 (en) 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
EP1395328B1 (en) * 2001-06-08 2006-08-16 Becton, Dickinson and Company Device for manipulating a needle or abrader array
SE0102736D0 (sv) * 2001-08-14 2001-08-14 Patrick Griss Side opened out-of-plane microneedles for microfluidic transdermal interfacing and fabrication process of side opened out-of-plane microneedles
US6881203B2 (en) 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
WO2003024507A2 (en) 2001-09-19 2003-03-27 Biovalve Technologies, Inc. Microneedles, microneedle arrays, and systems and methods relating to same
AU2002330083A1 (en) * 2001-09-21 2003-04-01 Biovalve Technologies, Inc. Gas pressure actuated microneedle arrays, and systems and methods relating to same
US6830562B2 (en) 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
US20030135166A1 (en) * 2001-09-28 2003-07-17 Gonnelli Robert R. Switchable microneedle arrays and systems and methods relating to same
CA2500453A1 (en) * 2001-09-28 2003-04-03 Biovalve Technologies, Inc. Microneedle with membrane
US6689100B2 (en) 2001-10-05 2004-02-10 Becton, Dickinson And Company Microdevice and method of delivering or withdrawing a substance through the skin of an animal
US20040120964A1 (en) * 2001-10-29 2004-06-24 Mikszta John A. Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses
JP2005511248A (ja) * 2001-10-29 2005-04-28 ベクトン・ディキンソン・アンド・カンパニー 物質を送達するための方法およびデバイス
US6908453B2 (en) 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US7858112B2 (en) 2002-02-28 2010-12-28 Lintec Corporation Percutaneous absorption system and percutaneous absorption method
JP4608187B2 (ja) * 2002-02-28 2011-01-05 リンテック株式会社 経皮吸収型製剤
AU2003209645A1 (en) * 2002-03-04 2003-09-16 Nano Pass Technologies Ltd. Devices and methods for transporting fluid across a biological barrier
EP3351277A1 (en) 2002-03-26 2018-07-25 Becton, Dickinson and Company Multi-stage fluid delivery device and method
JP4026745B2 (ja) * 2002-03-26 2007-12-26 財団法人大阪産業振興機構 医療用システムおよびその製造方法
US7115108B2 (en) * 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US7047070B2 (en) * 2002-04-02 2006-05-16 Becton, Dickinson And Company Valved intradermal delivery device and method of intradermally delivering a substance to a patient
US6780171B2 (en) * 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
WO2004000389A2 (en) * 2002-06-25 2003-12-31 Sung-Yun Kwon Rapidly dissolving micro-perforator for drug delivery and other applications
US6945952B2 (en) * 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
US6899838B2 (en) * 2002-07-12 2005-05-31 Becton, Dickinson And Company Method of forming a mold and molding a micro-device
AU2003251831B2 (en) 2002-07-19 2009-06-11 3M Innovative Properties Company Microneedle devices and microneedle delivery apparatus
US7250037B2 (en) * 2002-07-22 2007-07-31 Becton, Dickinson And Company Patch-like infusion device
US20040051019A1 (en) 2002-09-02 2004-03-18 Mogensen Lasse Wesseltoft Apparatus for and a method of adjusting the length of an infusion tube
US8062573B2 (en) * 2002-09-16 2011-11-22 Theraject, Inc. Solid micro-perforators and methods of use
DE10243917A1 (de) * 2002-09-20 2004-04-01 Udo Dr. Auweiler Vorrichtung zur subkutanen Abgabe eines pharmazeutischen Wirkstoffes
AU2003277306A1 (en) * 2002-10-07 2004-05-04 Biovalve Technologies, Inc. Microneedle array patch
IL152575A (en) * 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
IL152573A (en) * 2002-10-31 2009-11-18 Transpharma Medical Ltd A system for the transmission through the skin of a medical preparation against vomiting and nausea
IL152912A0 (en) * 2002-11-18 2003-06-24 Nanopass Ltd Micro needle systems
DK200201823A (da) 2002-11-26 2004-05-27 Maersk Medical As Forbindelsesstykke for en slangeforbindelse
EP1426662A1 (de) * 2002-12-06 2004-06-09 Boehringer Ingelheim International GmbH Kolbenpumpsystem
US7578954B2 (en) 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
EP1624914B1 (en) 2003-05-08 2008-04-16 Novo Nordisk A/S Internal needle inserter
EP1475113A1 (en) * 2003-05-08 2004-11-10 Novo Nordisk A/S External needle inserter
ATE474611T1 (de) * 2003-05-08 2010-08-15 Novo Nordisk As Eine auf die haut aufbringbare injektionsvorrichtung mit abtrennbarem betätigungsteil zum einführen der nadel
BRPI0412029A (pt) 2003-06-30 2006-09-05 Alza Corp formulações para microprojeções revestidas contendo contra-ìons não-voláteis
EP1502613A1 (en) 2003-08-01 2005-02-02 Novo Nordisk A/S Needle device with retraction means
EP2609946B1 (en) * 2003-08-12 2018-05-16 Becton, Dickinson and Company Patch-like infusion device with shielding member
US8961477B2 (en) 2003-08-25 2015-02-24 3M Innovative Properties Company Delivery of immune response modifier compounds
WO2005042054A2 (en) 2003-10-24 2005-05-12 Alza Corporation Pretreatment method and system for enhancing transdermal drug delivery
WO2005044139A2 (en) 2003-10-28 2005-05-19 Alza Corporation Method and apparatus for reducing the incidence of tobacco use
EP1680154B1 (en) 2003-10-31 2012-01-04 ALZA Corporation Self-actuating applicator for microprojection array
EP1713533A4 (en) * 2003-11-21 2008-01-23 Univ California METHOD AND / OR DEVICE FOR PUNKING A SURFACE FOR EXTRACTION, IN-SITU ANALYSIS AND / OR SUBSTANCE DELIVERY USING MICRONED NEEDLES
US8017145B2 (en) * 2003-12-22 2011-09-13 Conopco, Inc. Exfoliating personal care wipe article containing an array of projections
CA2552385C (en) * 2003-12-29 2013-07-23 3M Innovative Properties Company Medical devices and kits including same
US8551391B2 (en) * 2004-02-17 2013-10-08 Avery Dennison Corporation Method of making microneedles
WO2005082596A1 (en) * 2004-02-23 2005-09-09 3M Innovative Properties Company Method of molding for microneedle arrays
US7591618B2 (en) 2004-02-25 2009-09-22 Agency For Science, Technology And Research Machining method for micro abraders and micro abraders produced thereby
JP2005246595A (ja) * 2004-03-05 2005-09-15 Ritsumeikan マイクロニードルアレイ及びその製造方法
CA2560840C (en) 2004-03-24 2014-05-06 Corium International, Inc. Transdermal delivery device
KR101158939B1 (ko) 2004-03-26 2012-06-21 우노메디컬 에이/에스 주사세트를 위한 주사장치
WO2005094920A1 (en) 2004-03-30 2005-10-13 Novo Nordisk A/S Actuator system comprising lever mechanism
CN100402107C (zh) * 2004-03-31 2008-07-16 中国科学院理化技术研究所 金属微针阵列芯片及其制备方法和用途
ES2650188T3 (es) * 2004-06-10 2018-01-17 3M Innovative Properties Company Dispositivo y kit de aplicación de parches
US8062250B2 (en) 2004-08-10 2011-11-22 Unomedical A/S Cannula device
ITPD20040252A1 (it) * 2004-10-14 2005-01-14 Bidoia Sas Di Gianfranco Bidoi Irrigatore chirurgico
WO2006055802A1 (en) 2004-11-18 2006-05-26 3M Innovative Properties Company Microneedle array applicator and retainer
WO2006055795A1 (en) 2004-11-18 2006-05-26 3M Innovative Properties Company Low-profile microneedle array applicator
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
AU2005306426B2 (en) * 2004-11-18 2011-04-28 3M Innovative Properties Company Masking method for coating a microneedle array
JP5015787B2 (ja) 2004-11-18 2012-08-29 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイの接触コーティング法
US20080009801A1 (en) * 2004-12-02 2008-01-10 Nickel Janice H Method for dispensing material into a drug delivery device
WO2006062974A2 (en) 2004-12-07 2006-06-15 3M Innovative Properties Company Method of molding a microneedle
CA2589693A1 (en) 2004-12-10 2006-06-15 Unomedical A/S Inserter
EP1669100A1 (en) * 2004-12-13 2006-06-14 Debiotech S.A. Micro-needle
CN100571800C (zh) 2005-01-24 2009-12-23 诺和诺德公司 具有被保护的经皮设备的医疗设备
KR100679714B1 (ko) * 2005-02-07 2007-02-07 재단법인서울대학교산학협력재단 3차원 구조의 마이크로 스파이크 및 그 제조 방법
US7985199B2 (en) 2005-03-17 2011-07-26 Unomedical A/S Gateway system
WO2006101146A1 (ja) * 2005-03-22 2006-09-28 Transcutaneous Technologies Inc. イオントフォレーシス装置
JP4793806B2 (ja) * 2005-03-22 2011-10-12 Tti・エルビュー株式会社 イオントフォレーシス装置
US20060216461A1 (en) * 2005-03-23 2006-09-28 Tachauer Ernesto S Molding touch fastener elements
WO2006105146A2 (en) * 2005-03-29 2006-10-05 Arkal Medical, Inc. Devices, systems, methods and tools for continuous glucose monitoring
US7601284B2 (en) * 2005-04-06 2009-10-13 Velcro Industries B.V. Molding fastener elements on folded substrate
WO2006108185A1 (en) 2005-04-07 2006-10-12 3M Innovative Properties Company System and method for tool feedback sensing
US20080009802A1 (en) * 2005-04-25 2008-01-10 Danilo Lambino Method of treating acne with stratum corneum piercing device
US20060253079A1 (en) * 2005-04-25 2006-11-09 Mcdonough Justin Stratum corneum piercing device
US20070270738A1 (en) * 2005-04-25 2007-11-22 Wu Jeffrey M Method of treating ACNE with stratum corneum piercing patch
US20060283465A1 (en) * 2005-06-16 2006-12-21 Nickel Janice H Smart drug delivery system and a method of implementation thereof
WO2007002523A2 (en) 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
EP1896115B2 (en) * 2005-06-27 2020-01-22 3M Innovative Properties Company Microneedle cartridge assembly
AU2006261898B2 (en) * 2005-06-27 2011-11-03 3M Innovative Properties Company Microneedle array applicator device
US20070060837A1 (en) * 2005-08-18 2007-03-15 Seoul National University Industry Foundation Barb-wired micro needle made of single crystalline silicon and biopsy method and medicine injecting method using the same
US8118753B2 (en) * 2005-08-18 2012-02-21 Seoul National University Industry Foundation Barb-wired micro needle made of single crystalline silicon and biopsy method and medicine injecting method using the same
DE102005040251A1 (de) * 2005-08-24 2007-03-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Transcorneales System zur Abgabe eines Arzneimittel-Wirkstoffes
CA2629393C (en) * 2005-09-06 2014-06-10 Theraject, Inc. Solid solution perforator containing drug particle and/or drug-adsorbed particles
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US9358033B2 (en) * 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
ATE480278T1 (de) 2005-09-12 2010-09-15 Unomedical As Einfürungssystem für ein infusionsset mit einem ersten und zweiten federeinheit
JP2009509659A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 生体界面への活性物質の送達のイオントフォレーシス装置及び方法
US20080262416A1 (en) * 2005-11-18 2008-10-23 Duan Daniel C Microneedle Arrays and Methods of Preparing Same
WO2007061781A1 (en) * 2005-11-18 2007-05-31 3M Innovative Properties Company Coatable compositions, coatings derived therefrom and microarrays having such coatings
US9248317B2 (en) 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
US7885793B2 (en) 2007-05-22 2011-02-08 International Business Machines Corporation Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution
USD655807S1 (en) 2005-12-09 2012-03-13 Unomedical A/S Medical device
EP1962942A1 (en) * 2005-12-21 2008-09-03 3M Innovative Properties Company Microneedle devices
DE602006019153D1 (de) 2005-12-23 2011-02-03 Unomedical As Injektionsvorrichtung
US20070191811A1 (en) * 2006-02-10 2007-08-16 Joseph Berglund System and Method for Treating a Vascular Condition
WO2007098771A2 (en) 2006-02-28 2007-09-07 Unomedical A/S Inserter for infusion part and infusion part provided with needle protector
JP2009529400A (ja) * 2006-03-10 2009-08-20 アルザ コーポレイション 高バリア保持具を備えた微小突起アレイの適用
JP2009530880A (ja) 2006-03-13 2009-08-27 ノボ・ノルデイスク・エー/エス 複合通信手段を使用した電子装置の安全なペアリング
WO2007124411A1 (en) 2006-04-20 2007-11-01 3M Innovative Properties Company Device for applying a microneedle array
CN101460207B (zh) 2006-06-06 2012-03-21 诺沃-诺迪斯克有限公司 包括皮肤可安装设备及其包装件的组件
US8439838B2 (en) 2006-06-07 2013-05-14 Unomedical A/S Inserter for transcutaneous sensor
US8790311B2 (en) 2006-06-09 2014-07-29 Unomedical A/S Mounting pad
CN101500627B (zh) 2006-08-02 2012-03-14 优诺医疗有限公司 套管和输送装置
US20080058726A1 (en) * 2006-08-30 2008-03-06 Arvind Jina Methods and Apparatus Incorporating a Surface Penetration Device
NZ576637A (en) * 2006-10-25 2012-05-25 Novartis Ag Powder dispersion apparatus with and mediciment receptacles that are cut open using an elliptical arc shaped knife blade oriented to yaw between 4 and 12 degrees
EP1917990A1 (en) 2006-10-31 2008-05-07 Unomedical A/S Infusion set
CA2676221C (en) 2007-01-22 2016-12-20 Corium International, Inc. Applicators for microneedles
FR2912919B1 (fr) * 2007-02-22 2009-05-01 Bernard Perriere Dispositif d'injection miniaturise a usage medical
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
EP2146689B1 (en) 2007-04-16 2020-08-12 Corium, Inc. Solvent-cast microneedle arrays containing active
US8439861B2 (en) 2007-04-24 2013-05-14 Velcro Industries B.V. Skin penetrating touch fasteners
AU2008266382B2 (en) 2007-06-20 2013-06-27 Unomedical A/S A catheter and a method and an apparatus for making such catheter
KR20100049574A (ko) 2007-07-03 2010-05-12 우노메디컬 에이/에스 이중안정의 평형상태를 갖춘 주입기
ES2360842T3 (es) 2007-07-10 2011-06-09 Unomedical A/S Dispositivo de inserción con dos muelles.
WO2009010396A1 (en) 2007-07-18 2009-01-22 Unomedical A/S Insertion device with pivoting action
KR20090015449A (ko) * 2007-08-08 2009-02-12 현대자동차주식회사 수크로스 탄소 전구체로부터 결정성이 우수한 기공성그래파이트 탄소의 제조방법
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
US8557179B2 (en) 2007-10-31 2013-10-15 Novo Nordisk A/S Non-porous material as sterilization barrier
RU2010137844A (ru) 2008-02-13 2012-03-20 Уномедикал А/С (Dk) Уплотнение между канюльной частью и путем прохождения текучей среды
WO2009103759A1 (en) 2008-02-20 2009-08-27 Unomedical A/S Insertion device with horizontally moving part
EP2100850A1 (en) * 2008-03-11 2009-09-16 Stichting Voor De Technische Wetenschappen Microneedle array and a method for manufacturing microneedles
AU2009249610B2 (en) * 2008-05-21 2014-01-16 Theraject, Inc. Method of manufacturing solid solution perforator patches and uses thereof
MX2011005735A (es) 2008-12-22 2011-06-21 Unomedical As Dispositivo medico que comprende una almohadilla de adhesivo.
PL2401027T3 (pl) 2009-02-26 2018-04-30 The University Of North Carolina At Chapel Hill Układ do interwencyjnego dostarczania leku
CA2759850C (en) * 2009-04-24 2019-10-22 Corium International, Inc. Methods for manufacturing microprojection arrays
EP2275164A1 (en) 2009-07-15 2011-01-19 Debiotech S.A. Multichannel micro-needles
JP2013500099A (ja) 2009-07-30 2013-01-07 ウノメディカル・アー/エス 水平方向の可動部材を備えた挿入デバイス
BR112012001685B8 (pt) 2009-07-31 2021-06-22 3M Innovative Properties Co conjuntos de microagulhas ocas
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
JP2013500805A (ja) 2009-08-07 2013-01-10 ウノメディカル・アー/エス センサおよび1つまたは複数のカニューレを有する投与装置
US11096708B2 (en) 2009-08-07 2021-08-24 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
US8062568B2 (en) * 2009-08-27 2011-11-22 Korea University Research And Business Foundation Nano pattern writer
HU227748B1 (en) 2009-09-21 2012-02-28 Zoltan Dr Piros Microinfusion device for dosing insuline in the treatment of diabetes
US20110144591A1 (en) * 2009-12-11 2011-06-16 Ross Russell F Transdermal Delivery Device
DK3527239T3 (da) 2009-12-16 2021-04-26 Becton Dickinson Co Selvinjektionsindretning
DK2512560T3 (en) 2009-12-16 2018-07-16 Becton Dickinson Co Even injector device
EP2512552B1 (en) 2009-12-16 2015-02-25 Becton Dickinson and Company Self-injection device
IN2012DN05230A (es) 2009-12-16 2015-10-23 Becton Dickinson Co
EP2512579B1 (en) 2009-12-16 2016-11-30 Becton, Dickinson and Company Self-injection device
US10195340B2 (en) 2009-12-16 2019-02-05 Becton, Dickinson And Company Self-injection device
EP2552513B1 (en) 2010-03-30 2014-03-19 Unomedical A/S Medical device
EP2563453B1 (en) 2010-04-28 2017-02-08 Kimberly-Clark Worldwide, Inc. Nanopatterned medical device with enhanced cellular interaction and method for its forming
CA2796965C (en) 2010-04-28 2019-04-16 Kimberly-Clark Worldwide, Inc. Method for increasing permeability of an epithelial barrier
MX336139B (es) 2010-04-28 2016-01-08 Kimberly Clark Co Dispositivos medicos para la entrega de arn de interferencia corta.
RU2585159C2 (ru) 2010-04-28 2016-05-27 Кимберли-Кларк Ворлдвайд, Инк. Устройство доставки лекарственного средства, применяемого при ревматоидном артрите
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル, インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
US9125625B2 (en) 2010-06-10 2015-09-08 The Regents Of The University Of California Textile-based printable electrodes for electrochemical sensing
CN101905856B (zh) * 2010-06-11 2012-10-10 北京大学 一种用于透皮给药的平面空心微针的制备方法
DE102010038733A1 (de) * 2010-07-30 2012-02-02 Robert Bosch Gmbh Modulare Mikronadel-Transportvorrichtung
JP5718622B2 (ja) * 2010-08-31 2015-05-13 Asti株式会社 マイクロニードルアレイ装置
EP2611478B1 (en) 2010-09-02 2022-08-17 Becton, Dickinson and Company Self-injection device having needle cover with activation preventer
WO2012038959A2 (en) * 2010-09-21 2012-03-29 Israel Shamir Lebovitz Multi-directional needle
EP2433663A1 (en) 2010-09-27 2012-03-28 Unomedical A/S Insertion system
EP2436412A1 (en) 2010-10-04 2012-04-04 Unomedical A/S A sprinkler cannula
US10441767B2 (en) * 2010-10-27 2019-10-15 Asti Corporation Jig for microneedle array placement and microneedle array device
CN102641549B (zh) * 2011-02-18 2016-05-04 帕洛阿尔托研究中心公司 包括微针的透粘膜药物输送装置和方法
US8696637B2 (en) 2011-02-28 2014-04-15 Kimberly-Clark Worldwide Transdermal patch containing microneedles
KR101241059B1 (ko) * 2011-03-04 2013-03-11 연세대학교 산학협력단 마이크로 니들을 이용한 혈관외벽 장착 약물 전달장치 및 약물 전달방법
US8636696B2 (en) 2011-06-10 2014-01-28 Kimberly-Clark Worldwide, Inc. Transdermal device containing microneedles
EP2739333A1 (en) * 2011-08-05 2014-06-11 Unitract Syringe Pty Ltd Cannula with controlled depth of insertion
US9737247B2 (en) 2011-09-02 2017-08-22 The Regents Of The University Of California Microneedle arrays for biosensing and drug delivery
CN103957962B (zh) 2011-10-05 2017-07-07 犹诺医药有限公司 用于同时插入多个经皮部分的插入物
EP2583715A1 (en) 2011-10-19 2013-04-24 Unomedical A/S Infusion tube system and method for manufacture
US9440051B2 (en) 2011-10-27 2016-09-13 Unomedical A/S Inserter for a multiplicity of subcutaneous parts
US20170246439A9 (en) 2011-10-27 2017-08-31 Kimberly-Clark Worldwide, Inc. Increased Bioavailability of Transdermally Delivered Agents
CN104039382B (zh) 2011-10-27 2018-01-12 金伯利-克拉克环球有限公司 高粘度生物活性剂的经皮递送
KR20140079429A (ko) 2011-10-27 2014-06-26 킴벌리-클라크 월드와이드, 인크. 생체활성 제제를 전달하기 위한 이식형 기구
JP5845808B2 (ja) * 2011-10-28 2016-01-20 凸版印刷株式会社 マイクロニードルデバイスおよびその製造方法
JP5788019B2 (ja) * 2011-11-18 2015-09-30 南部化成株式会社 経皮投薬装置
CA2896188C (en) 2012-12-21 2021-02-23 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
RU2679107C2 (ru) 2013-01-21 2019-02-05 Пхэан Эстетикс Инк. Микроигла, форма для ее изготовления и способ изготовления микроиглы
CN103157178B (zh) * 2013-02-05 2014-12-31 北京化工大学 精确控制微针插入长度的印章式工具
US10245422B2 (en) 2013-03-12 2019-04-02 Corium International, Inc. Microprojection applicators and methods of use
EP2968751B1 (en) 2013-03-15 2022-11-30 Corium, Inc. Multiple impact microprojection applicators
CA2906541C (en) 2013-03-15 2022-06-21 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
AU2014233541B2 (en) 2013-03-15 2018-11-22 Corium Pharma Solutions, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US10384045B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
WO2015017561A1 (en) 2013-07-30 2015-02-05 Zosano Pharma, Inc. Low-profile microneedle patch applicator
US9987427B1 (en) 2014-06-24 2018-06-05 National Technology & Engineering Solutions Of Sandia, Llc Diagnostic/drug delivery “sense-respond” devices, systems, and uses thereof
EP2974758A1 (de) * 2014-07-15 2016-01-20 LTS LOHMANN Therapie-Systeme AG Zylinder-Kolben-Einheit mit Kanülen
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
JP5967595B2 (ja) * 2014-09-08 2016-08-10 株式会社かいわ 穿刺器具
NL2013654B1 (nl) * 2014-10-20 2016-08-11 Helène Tamara Witteman Amber Draagbare injectie-inrichting voor draagbare bevestiging aan een lichaamsdeel, voor het in een draagtoestand injecteren van een geneesmiddel via de huid van het lichaamsdeel.
JP6906885B2 (ja) 2014-11-14 2021-07-21 ロレアル しわを減少させるためのマイクロニードルシート
CN104307098B (zh) * 2014-11-15 2016-09-07 唐晨 微针给药装置及其制造方法
EP3235539A4 (en) * 2014-12-16 2018-07-18 Juvic Inc. Microcellular microstructure and method for manufacturing same
CN107206220A (zh) * 2015-02-16 2017-09-26 凸版印刷株式会社 微针
CN111643804B (zh) * 2015-03-18 2022-07-19 凸版印刷株式会社 药剂施予装置
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
CN108601932A (zh) * 2016-01-28 2018-09-28 株式会社理光 微针阵列和微针片
JP2017176652A (ja) * 2016-03-31 2017-10-05 花王株式会社 微細中空突起具
CN105963855A (zh) * 2016-06-22 2016-09-28 成都市亿泰科技有限公司 一种含分离式储药囊的微针给药贴片
CN105999533B (zh) * 2016-06-30 2022-01-25 山东中医药大学附属医院 药物夹层敷贴袋
WO2019036609A1 (en) * 2017-08-17 2019-02-21 New York University BONE GROWTH STIMULATOR AND METHODS OF USE
TWI656893B (zh) * 2017-10-27 2019-04-21 研能科技股份有限公司 穿戴式人體胰島素注入供液裝置
TWI666036B (zh) * 2017-10-27 2019-07-21 研能科技股份有限公司 穿戴式人體胰島素注入供液裝置
TWI657842B (zh) * 2017-10-27 2019-05-01 研能科技股份有限公司 人體胰島素注入之供液裝置
US11844919B2 (en) * 2018-01-03 2023-12-19 The Trustees Of Columbia University In The City Of New York Microneedle for local delivery of therapeutic agent
JP7305311B2 (ja) 2018-05-30 2023-07-10 ロレアル マイクロニードルシート
JP2020002084A (ja) 2018-06-29 2020-01-09 ロレアル マイクロニードルシートを使用する美容方法
JP7335061B2 (ja) 2018-06-29 2023-08-29 ロレアル マイクロニードルシートを使用する美容方法
JP2020018327A (ja) 2018-07-17 2020-02-06 ロレアル マイクロニードルシート
JP2020099513A (ja) 2018-12-21 2020-07-02 ロレアル マイクロニードルシートを使用するキット及び美容方法
WO2020188484A1 (en) * 2019-03-19 2020-09-24 King Abdullah University Of Science And Technology Miniaturized delivery system and method
CN110478613B (zh) 2019-08-22 2022-08-09 京东方科技集团股份有限公司 递送制剂的器件、设备及器件中针头阵列的制备方法
JP2021094146A (ja) 2019-12-16 2021-06-24 ロレアル マイクロニードルシートを使用する美容方法
CA3159840A1 (en) * 2019-12-20 2021-06-24 Maxime ETTORI Microneedle array, actuator and method of use
EP3854375A1 (en) 2020-01-23 2021-07-28 Paean Aesthetics Inc Micro-spicule composition to control its shape and method for producing the same
FR3113843B1 (fr) 2020-09-07 2024-03-15 Oreal Kit et traitement cosmetique utilisant une feuille de micro-aiguilles
US20230226332A1 (en) 2020-06-17 2023-07-20 L'oreal Kit and cosmetic process using microneedle sheet
GB2622909A (en) 2020-07-29 2024-04-03 Biolinq Incorporated Continuous analyte monitoring system with microneedle array
DE102020133395A1 (de) 2020-12-14 2022-06-15 Lts Lohmann Therapie-Systeme Ag. Wirkstoffabgabesystem
SE545874C2 (en) 2021-05-08 2024-02-27 Biolinq Incorporated Fault detection for microneedle array based continuous analyte monitoring device
FR3135206A1 (fr) 2022-05-05 2023-11-10 L'oreal Processus cosmétique utilisant une feuille de micro-aiguilles
FR3139007A1 (fr) 2022-08-23 2024-03-01 L'oreal Composition convenant pour des traitements cosmétiques de substance kératineuse

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US4622031A (en) * 1983-08-18 1986-11-11 Drug Delivery Systems Inc. Indicator for electrophoretic transcutaneous drug delivery device
GB2221394B (en) * 1988-08-05 1992-03-04 Eilert Eilertsen An injection device
CA2149836C (en) * 1994-05-23 1999-07-06 Sang Bae Choi Perforating device for dermal administration

Also Published As

Publication number Publication date
TW375528B (en) 1999-12-01
EE04006B1 (et) 2003-04-15
NO316313B1 (no) 2004-01-12
NZ313984A (en) 2000-04-28
CA2226718C (en) 2007-12-11
CN1190904A (zh) 1998-08-19
CO4700491A1 (es) 1998-12-29
SK284358B6 (sk) 2005-02-04
NO980147L (no) 1998-03-13
AU722943B2 (en) 2000-08-17
EP0840634A1 (de) 1998-05-13
PL181658B1 (pl) 2001-08-31
EP0840634B1 (de) 2001-10-31
HK1010844A1 (en) 1999-07-02
KR19990028966A (ko) 1999-04-15
BG102200A (en) 1998-08-31
AR004499A1 (es) 1998-12-16
HUP9802773A2 (en) 1999-06-28
KR100430703B1 (ko) 2004-07-22
DK0840634T3 (da) 2002-02-18
TR199800048T1 (xx) 1998-04-21
PT840634E (pt) 2002-02-28
JPH11509123A (ja) 1999-08-17
SK4998A3 (en) 1998-09-09
MX9800401A (es) 1998-04-30
BR9609796A (pt) 1999-03-16
DE19525607A1 (de) 1997-01-16
US6132755A (en) 2000-10-17
UA62918C2 (en) 2004-01-15
RU2209640C2 (ru) 2003-08-10
ATE207769T1 (de) 2001-11-15
ES2163035T3 (es) 2002-01-16
DE59608081D1 (de) 2001-12-06
HU222342B1 (hu) 2003-06-28
PL324530A1 (en) 1998-06-08
AU6656796A (en) 1997-02-18
HUP9802773A3 (en) 2000-06-28
CN1183979C (zh) 2005-01-12
NO980147D0 (no) 1998-01-13
CA2226718A1 (en) 1997-02-06
RO118738B1 (ro) 2003-10-30
CZ11898A3 (cs) 1998-06-17
BG63142B1 (bg) 2001-05-31
CZ290458B6 (cs) 2002-07-17
IL122907A0 (en) 1998-08-16
ZA965931B (en) 1998-03-12
WO1997003718A1 (de) 1997-02-06
EE9800025A (et) 1998-08-17

Similar Documents

Publication Publication Date Title
UY24277A1 (es) Sistema transcorneal de liberacion de medicamentos
ES2561824T3 (es) Ambiente a baja presión para dispositivos de transferencia de fluidos
DE69312916D1 (de) Wirkstoffabgabevorrichtungen
DK1539266T3 (da) Medicinsk anordning til dispensering af lægemidler
NO20034684D0 (no) Innretning for administrering av midler gjennom stratum corcum
BRPI0517501A (pt) dispositivo médico apropriado para uso na administração de um componente ativo na ou através da pele
AR008242A1 (es) Dispositivo para atravesar el estrato corneo de una superficie corporal
RU98102774A (ru) Транскорнеальная система высвобождения лекарства
ATE298259T1 (de) Vorrichtung zur lokalen verabreichung einer arznei in einer körperhöhle
AR046307A1 (es) Metodo de pretratamiento y sistema para mejorar la administracion transdermica de drogas
ES2165955T3 (es) Dispositivo para la aplicacion de un liquido medicamentoso sobre la mucosa de las cavidades corporales.
DE60219607D1 (de) Flexible mikrochip-vorrichtungen zur ophthalmologischen und anderen applikation
AR046922A1 (es) Sistema y metodo para la administracion transdermica de vacunas.
PT1037686E (pt) Aparelho para potenciar o fluxo de agente transdermico
EP1982701A3 (en) Sustained Release Drug Delivery Devices, Methods of Use, and Methods of Manufacturing Thereof
DK0458879T3 (da) Intravenøst system til indgivelse af et virksom middel
ES2021028B3 (es) Dispositivo para liberacion de farmacos en 2 etapas.
BR0012152A (pt) Sistema de microrreservatórios na base de polissiloxanos e solventes ambifìlicos
AR000901A1 (es) Metodo y disposicion en linea para el tratamiento extracorporal de sangre
US20230414911A1 (en) Intradermal Active Ingredient Delivery System
EP1752189A3 (en) Microprojection array having a beneficial agent containing coating
BRPI0608447A2 (pt) dispositivos de microjato e métodos para administração de medicamento
DE60006109D1 (de) Implantierbares medikamentenabgabesystem
EP0934753A3 (en) Needleless medical device for delivering of terapeutic agent
RU2000108947A (ru) Метод ультразвукового исследования кровообращения в половом члене

Legal Events

Date Code Title Description
VENC Patent expired

Effective date: 20160711