ATE280615T1 - Elektrotransportvorrichtung mit klingen - Google Patents

Elektrotransportvorrichtung mit klingen

Info

Publication number
ATE280615T1
ATE280615T1 AT99942531T AT99942531T ATE280615T1 AT E280615 T1 ATE280615 T1 AT E280615T1 AT 99942531 T AT99942531 T AT 99942531T AT 99942531 T AT99942531 T AT 99942531T AT E280615 T1 ATE280615 T1 AT E280615T1
Authority
AT
Austria
Prior art keywords
blades
transport device
electric transport
reservoir
compound
Prior art date
Application number
AT99942531T
Other languages
English (en)
Inventor
Ying Sun
Ralph W Oakeson
Stephen J Wisniewski
Jonas C T Wang
Susan M Niemiec
Original Assignee
Johnson & Johnson Consumer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson Consumer filed Critical Johnson & Johnson Consumer
Application granted granted Critical
Publication of ATE280615T1 publication Critical patent/ATE280615T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Refuse Collection And Transfer (AREA)
  • Crushing And Pulverization Processes (AREA)
  • Details Of Rigid Or Semi-Rigid Containers (AREA)
AT99942531T 1998-08-31 1999-08-30 Elektrotransportvorrichtung mit klingen ATE280615T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9849498P 1998-08-31 1998-08-31
US12970599P 1999-04-16 1999-04-16
PCT/US1999/019713 WO2000012173A1 (en) 1998-08-31 1999-08-30 Electrotransport device comprising blades

Publications (1)

Publication Number Publication Date
ATE280615T1 true ATE280615T1 (de) 2004-11-15

Family

ID=26794791

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99942531T ATE280615T1 (de) 1998-08-31 1999-08-30 Elektrotransportvorrichtung mit klingen

Country Status (8)

Country Link
US (1) US6532386B2 (de)
EP (1) EP1109594B1 (de)
JP (1) JP2002523195A (de)
CN (1) CN1315877A (de)
AT (1) ATE280615T1 (de)
CA (1) CA2341446C (de)
DE (1) DE69921489T2 (de)
WO (1) WO2000012173A1 (de)

Families Citing this family (209)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
AU3672000A (en) * 1999-10-14 2001-04-23 Pola Chemical Industries Inc. Compositions for electroporation
US8024048B2 (en) * 2000-03-13 2011-09-20 Ionix Medical Inc. Method and device for treating cancer with electrical therapy in conjunction with chemotherapeutic agents and radiation therapy
US7742811B2 (en) * 2000-03-13 2010-06-22 Onco Stim Implantable device and method for the electrical treatment of cancer
GB0017999D0 (en) * 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US6821281B2 (en) * 2000-10-16 2004-11-23 The Procter & Gamble Company Microstructures for treating and conditioning skin
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
HUP0302924A2 (en) 2000-10-26 2003-12-29 Alza Corp Transdermal drug delivery devices having coated microprotrusions
EP1345646A2 (de) * 2000-12-14 2003-09-24 Georgia Tech Research Corporation Mikronadel-vorrichtungen und deren herstellung
US20050187581A1 (en) * 2000-12-18 2005-08-25 Hakuju Institute For Health Science, Co., Ltd. Methods of treating disorders with electric fields
US20030233124A1 (en) * 2000-12-18 2003-12-18 Hajuku Institute For Health Science Co., Ltd. Methods of treating disorders by altering ion flux across cell membranes with electric fields
US6663820B2 (en) * 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
NZ528750A (en) * 2001-04-04 2005-10-28 Alza Corp Transdermal electrotransport delivery device including an antimicrobial compatible reservoir composition
EP3251722B1 (de) * 2001-04-20 2020-06-17 ALZA Corporation Mikroprojektionsanordnung mit einer beschichtung, der ein vorteilhaftes mittel enthält und beschichtungsverfahren dafuer
CN100349632C (zh) * 2001-04-20 2007-11-21 阿尔扎公司 具有包含有益药剂的涂层的微小突出物阵列
US20040087992A1 (en) * 2002-08-09 2004-05-06 Vladimir Gartstein Microstructures for delivering a composition cutaneously to skin using rotatable structures
JP2005503210A (ja) * 2001-09-14 2005-02-03 ザ プロクター アンド ギャンブル カンパニー 回転可能構造を用いて皮膚を介して組成物を皮膚に送達するための微細構造
US6689100B2 (en) 2001-10-05 2004-02-10 Becton, Dickinson And Company Microdevice and method of delivering or withdrawing a substance through the skin of an animal
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US6780171B2 (en) 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
US7115108B2 (en) 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US7047070B2 (en) 2002-04-02 2006-05-16 Becton, Dickinson And Company Valved intradermal delivery device and method of intradermally delivering a substance to a patient
WO2004037341A2 (en) 2002-05-07 2004-05-06 Schroeppel Edward A Method and device for treating concer with electrical therapy in conjunction with chemotherapeutic agents and radiation therapy
US6945952B2 (en) * 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
CN102872526A (zh) 2002-07-19 2013-01-16 3M创新有限公司 微针装置和微针施用设备
IL152575A (en) * 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
US7483738B2 (en) * 2002-11-29 2009-01-27 Power Paper Ltd. Combination stimulating and exothermic heating device and method of use thereof
CA2511315A1 (en) * 2002-12-31 2004-07-22 The Johns Hopkins University Wound healing method and kits
WO2004073794A2 (en) * 2003-02-19 2004-09-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Device, methods and sponges for iontophoretic drug delivery
US7578954B2 (en) * 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
CN1750855A (zh) * 2003-03-10 2006-03-22 株式会社钟化 支架
US8734421B2 (en) 2003-06-30 2014-05-27 Johnson & Johnson Consumer Companies, Inc. Methods of treating pores on the skin with electricity
US7480530B2 (en) 2003-06-30 2009-01-20 Johnson & Johnson Consumer Companies, Inc. Device for treatment of barrier membranes
EP1638523B8 (de) 2003-06-30 2013-12-25 ALZA Corporation Formulierungen für beschichtete mikrovorsprünge mit nichtflüchtigen gegenionen
US7477939B2 (en) 2003-06-30 2009-01-13 Johnson & Johnson Consumer Companies, Inc. Methods of treating a wound with galvanic generated electricity
US8097135B2 (en) * 2003-07-09 2012-01-17 Auburn University Reversible electrochemical sensors for polyions
TW200514596A (en) * 2003-08-04 2005-05-01 Alza Corp Method and device for enhancing transdermal agent flux
JP2007503268A (ja) * 2003-08-25 2007-02-22 スリーエム イノベイティブ プロパティズ カンパニー 免疫応答修飾化合物の送達
CA2542874A1 (en) * 2003-10-23 2005-05-12 Alza Corporation Compositions of stabilized dna for coating microprojections
CN1897882A (zh) * 2003-10-28 2007-01-17 阿尔扎公司 降低烟草使用频率的方法和装置
CN1889994A (zh) * 2003-12-10 2007-01-03 艾克若克斯Dds有限公司 伴随透皮或局部药物输送的不希望的效果的治疗方法
WO2005065765A1 (en) * 2003-12-29 2005-07-21 3M Innovative Properties Company Medical devices and kits including same
CN1636505B (zh) * 2004-01-09 2011-11-09 希森美康株式会社 提取器具、提取装置和血糖值测量装置
JP2007523771A (ja) * 2004-02-23 2007-08-23 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイの成形方法
US8666486B2 (en) * 2004-03-04 2014-03-04 Hadasit Medical Research Services & Development Limited Safe device for iontophoretic delivery of drugs
AU2005228145B2 (en) * 2004-03-24 2011-03-03 Corium Pharma Solutions, Inc. Transdermal delivery device
US20050222646A1 (en) * 2004-04-06 2005-10-06 Kai Kroll Method and device for treating cancer with modified output electrical therapy
US20070260290A1 (en) * 2004-05-11 2007-11-08 Akikuni Hara Non-Pharmacological Electric Filed Method and Apparatus for Treating and Improving Rheumatism and Pain
JP5007427B2 (ja) 2004-05-13 2012-08-22 アルザ コーポレイション 副甲状腺ホルモン剤の経皮送達のための装置および方法
US7315758B2 (en) * 2004-06-03 2008-01-01 Lynntech, Inc. Transdermal delivery of therapeutic agent
EP1773444B1 (de) * 2004-06-10 2017-09-20 3M Innovative Properties Company Vorrichtung und kit zur pflasterapplikation
US20060030811A1 (en) * 2004-08-03 2006-02-09 Wong Patrick S Method and device for enhancing transdermal agent flux
ITPD20040252A1 (it) * 2004-10-14 2005-01-14 Bidoia Sas Di Gianfranco Bidoi Irrigatore chirurgico
US20060095001A1 (en) * 2004-10-29 2006-05-04 Transcutaneous Technologies Inc. Electrode and iontophoresis device
WO2006055729A1 (en) * 2004-11-16 2006-05-26 Transcutaneous Technologies Inc. Iontophoretic device and method for administering immune response-enhancing agents and compositions
WO2006055844A2 (en) 2004-11-18 2006-05-26 3M Innovative Properties Company Method of contact coating a microneedle array
AU2005306426B2 (en) * 2004-11-18 2011-04-28 3M Innovative Properties Company Masking method for coating a microneedle array
CN101060883B (zh) 2004-11-18 2010-06-23 3M创新有限公司 低轮廓微针阵列施放器
AU2005306429B2 (en) 2004-11-18 2011-04-14 3M Innovative Properties Company Microneedle array applicator and retainer
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
CA2589733C (en) 2004-12-07 2014-02-11 3M Innovative Properties Company Method of molding a microneedle
US20060263257A1 (en) * 2004-12-13 2006-11-23 Beauchamp Jesse L Optical gas sensor based on dyed high surface area substrates
CA2596075A1 (en) * 2005-01-31 2006-08-10 Alza Corporation Coated microprojections having reduced variability and method for producing same
JP5301985B2 (ja) * 2005-04-07 2013-09-25 スリーエム イノベイティブ プロパティズ カンパニー ツールフィードバック感知のためのシステム及び方法
US20070270738A1 (en) * 2005-04-25 2007-11-22 Wu Jeffrey M Method of treating ACNE with stratum corneum piercing patch
US20060253078A1 (en) * 2005-04-25 2006-11-09 Wu Jeffrey M Method of treating skin disorders with stratum corneum piercing device
US20080009802A1 (en) * 2005-04-25 2008-01-10 Danilo Lambino Method of treating acne with stratum corneum piercing device
US20060258973A1 (en) * 2005-04-27 2006-11-16 Kevin Volt Micro-current Iontophoretic Percutaneous Absorptive Patch
JP2006334164A (ja) * 2005-06-02 2006-12-14 Transcutaneous Technologies Inc イオントフォレーシス装置及びその制御方法
JP2006346368A (ja) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc イオントフォレーシス装置及びその製造方法
WO2007002523A2 (en) * 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
EP2474338B1 (de) * 2005-06-27 2013-07-24 3M Innovative Properties Company Vorrichtung zum Aufbringen einer Mikronadelanordnung
AU2006261899B2 (en) 2005-06-27 2012-05-10 Kindeva Drug Delivery L.P. Microneedle cartridge assembly and method of applying
US20090214625A1 (en) * 2005-07-15 2009-08-27 Mizuo Nakayama Drug delivery patch
JP2007037868A (ja) * 2005-08-05 2007-02-15 Transcutaneous Technologies Inc 経皮投与装置及びその制御方法
US8386030B2 (en) * 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US8295922B2 (en) * 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US20070060860A1 (en) * 2005-08-18 2007-03-15 Transcutaneous Technologies Inc. Iontophoresis device
WO2007026672A1 (ja) * 2005-08-29 2007-03-08 Transcu Ltd. イオントフォレーシス用汎用性電解液組成物
JPWO2007029611A1 (ja) * 2005-09-06 2009-03-19 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
CN101687094B (zh) * 2005-09-06 2012-09-26 谢拉杰克特股份有限公司 含有药物颗粒和/或药物吸附颗粒的固体溶液穿孔器
US20070112294A1 (en) * 2005-09-14 2007-05-17 Transcutaneous Technologies Inc. Iontophoresis device
CA2619665A1 (en) * 2005-09-15 2007-03-22 Tti Ellebeau, Inc. Rod type iontophoresis device
EP1925335A1 (de) * 2005-09-16 2008-05-28 Tti Ellebeau, Inc. Katheterartiges iontophoresegerät
JPWO2007037324A1 (ja) * 2005-09-28 2009-04-09 Ｔｔｉ・エルビュー株式会社 乾燥型イオントフォレーシス用電極構造体
US20070071807A1 (en) * 2005-09-28 2007-03-29 Hidero Akiyama Capsule-type drug-releasing device and capsule-type drug-releasing device system
US20070078445A1 (en) * 2005-09-30 2007-04-05 Curt Malloy Synchronization apparatus and method for iontophoresis device to deliver active agents to biological interfaces
WO2007041322A2 (en) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Iontophoretic delivery of active agents conjugated to nanoparticles
US20070232983A1 (en) * 2005-09-30 2007-10-04 Smith Gregory A Handheld apparatus to deliver active agents to biological interfaces
KR20080066712A (ko) * 2005-09-30 2008-07-16 티티아이 엘뷰 가부시키가이샤 관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법
JP4902543B2 (ja) * 2005-09-30 2012-03-21 Ｔｔｉ・エルビュー株式会社 形状記憶セパレータを有するイオントフォレーシス用電極構造体およびそれを用いたイオントフォレーシス装置
US20070078376A1 (en) * 2005-09-30 2007-04-05 Smith Gregory A Functionalized microneedles transdermal drug delivery systems, devices, and methods
WO2007041323A1 (en) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Iontophoretic delivery of vesicle-encapsulated active agents
WO2007037476A1 (ja) * 2005-09-30 2007-04-05 Tti Ellebeau, Inc. 睡眠導入剤と興奮剤の投与量および投与時期を制御するイオントフォレーシス装置
JP2009509659A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 生体界面への活性物質の送達のイオントフォレーシス装置及び方法
JP2009509656A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 生体界面に活性物質を送達するイオントフォレーシス装置における動作不良を検出するための方法及びシステム
JP2009509657A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 生体界面への活性物質の送達のイオントフォレーシス装置及び方法
US20070197955A1 (en) * 2005-10-12 2007-08-23 Transcutaneous Technologies Inc. Mucous membrane adhesion-type iontophoresis device
EP1948139A4 (de) * 2005-11-18 2012-04-04 3M Innovative Properties Co Überziehbare zusammensetzungen, daraus erhaltene überzüge und mikroanordnungen mit diesen überzügen
US20080262416A1 (en) * 2005-11-18 2008-10-23 Duan Daniel C Microneedle Arrays and Methods of Preparing Same
EP1962942A1 (de) * 2005-12-21 2008-09-03 3M Innovative Properties Company Mikronadelvorrichtungen
US8632801B2 (en) 2005-12-28 2014-01-21 Alza Corporation Stable therapeutic formulations
WO2007079116A1 (en) * 2005-12-28 2007-07-12 Tti Ellebeau, Inc. Electroosmotic pump apparatus and method to deliver active agents to biological interfaces
WO2007079190A2 (en) * 2005-12-29 2007-07-12 Tti Ellebeau, Inc. Device and method for enhancing immune response by electrical stimulation
EP1965858A2 (de) * 2005-12-30 2008-09-10 Tti Ellebeau, Inc. System und verfahren zur fernsteuerung eines iontophoresegerätes
WO2007079193A2 (en) * 2005-12-30 2007-07-12 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
US20080004564A1 (en) * 2006-03-30 2008-01-03 Transcutaneous Technologies Inc. Controlled release membrane and methods of use
WO2007124411A1 (en) * 2006-04-20 2007-11-01 3M Innovative Properties Company Device for applying a microneedle array
WO2007143796A1 (en) 2006-06-15 2007-12-21 Seagull Ip Pty Ltd A delivery system and process
US20080058701A1 (en) * 2006-07-05 2008-03-06 Transcutaneous Technologies Inc. Delivery device having self-assembling dendritic polymers and method of use thereof
WO2008013913A2 (en) * 2006-07-26 2008-01-31 Aciont, Inc. Method and device for minimally invasive site specific ocular drug delivery
MX2009002321A (es) * 2006-09-05 2009-03-23 Tti Ellebeau Inc Sistemas, dispositivos y metodos de suministro transdermico de farmacos que utilizan suministros de energia inductiva.
WO2008062365A2 (en) * 2006-11-24 2008-05-29 Koninklijke Philips Electronics N.V. Iontophoretic device
JP5383497B2 (ja) * 2006-12-01 2014-01-08 Ｔｔｉ・エルビュー株式会社 装置、例として経皮送達装置に給電し且つ／又は当該装置を制御するシステム及び装置
US20080152592A1 (en) * 2006-12-21 2008-06-26 Bayer Healthcare Llc Method of therapeutic drug monitoring
EP2121111B1 (de) * 2007-01-22 2018-03-14 Corium International, Inc. Applikator für mikronadelanordnung
WO2008114220A2 (en) * 2007-03-19 2008-09-25 Insuline Medical Ltd. Device for drug delivery and associated connections thereto
US20100210932A1 (en) * 2007-03-20 2010-08-19 Bayer Healthcare Llc Method of analyzing an analyte
US9114238B2 (en) * 2007-04-16 2015-08-25 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
AU2014200648B2 (en) * 2007-04-16 2015-09-24 Corium Pharma Solutions, Inc. Solvent-cast microneedle arrays containing active
US8439861B2 (en) 2007-04-24 2013-05-14 Velcro Industries B.V. Skin penetrating touch fasteners
US8079269B2 (en) * 2007-05-16 2011-12-20 Rosemount Inc. Electrostatic pressure sensor with porous dielectric diaphragm
MX2009012273A (es) * 2007-05-18 2010-04-09 Tti Ellebeau Inc Dispositivos de suministro transd?rmico que aseguran la liberaci?n mejorada de un principio activo a trav?s de una interfaz biol?gica.
JP2010187707A (ja) * 2007-06-12 2010-09-02 Hokkaido Univ インスリンを封入したイオントフォレーシス用リポソーム製剤
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
JP5178132B2 (ja) * 2007-10-11 2013-04-10 キヤノン株式会社 画像処理システム並びに画像処理方法
JP5584202B2 (ja) * 2008-05-21 2014-09-03 セラジェクト， インコーポレイテッド 固溶体穿孔器パッチの製造方法及びその使用
WO2009149308A2 (en) * 2008-06-04 2009-12-10 Seventh Sense Biosystems, Inc. Compositions and methods for rapid one-step diagnosis
US9597145B2 (en) * 2008-08-20 2017-03-21 Prostacare Pty Ltd Non-thermal ablation system for treating tissue
US8150525B2 (en) 2008-08-27 2012-04-03 Johnson & Johnson Consumer Companies, Inc. Treatment of hyperhydrosis
AR073575A1 (es) * 2008-09-10 2010-11-17 Transcu Ltd Aparato y metodo para dispensar basados en hpc liquidos viscosos en sustratos porosos por ejemplo proceso continuo basado en bandas
US9113836B2 (en) 2009-03-02 2015-08-25 Seventh Sense Biosystems, Inc. Devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications
US20110105872A1 (en) * 2009-10-30 2011-05-05 Seventh Sense Biosystems, Inc. Systems and methods for application to skin and control of actuation, delivery, and/or perception thereof
WO2012018486A2 (en) 2010-07-26 2012-02-09 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
US20110172508A1 (en) * 2010-01-13 2011-07-14 Seventh Sense Biosystems, Inc. Sampling device interfaces
US20120089232A1 (en) 2009-03-27 2012-04-12 Jennifer Hagyoung Kang Choi Medical devices with galvanic particulates
WO2010124255A2 (en) * 2009-04-24 2010-10-28 Corium International, Inc. Methods for manufacturing microprojection arrays
US20110092881A1 (en) * 2009-05-08 2011-04-21 Isis Biopolymer Inc. Iontophoretic device with contact sensor
JP2012529353A (ja) * 2009-06-09 2012-11-22 Ｔｔｉ・エルビュー株式会社 長寿命高容量電極、装置および製造方法
US8882748B2 (en) 2009-10-08 2014-11-11 Palo Alto Research Center Incorporated Transmucosal drug delivery device and method including chemical permeation enhancers
US9017310B2 (en) * 2009-10-08 2015-04-28 Palo Alto Research Center Incorporated Transmucosal drug delivery device and method including microneedles
US9014799B2 (en) * 2009-10-08 2015-04-21 Palo Alto Research Center Incorporated Transmucosal drug delivery device and method including electrically-actuated permeation enhancement
WO2011065972A2 (en) * 2009-11-24 2011-06-03 Seventh Sense Biosystems, Inc. Patient-enacted sampling technique
WO2011088214A2 (en) * 2010-01-13 2011-07-21 Seventh Sense Biosystems, Inc. Rapid delivery and/or withdrawal of fluids
US8476227B2 (en) 2010-01-22 2013-07-02 Ethicon Endo-Surgery, Inc. Methods of activating a melanocortin-4 receptor pathway in obese subjects
US9044606B2 (en) 2010-01-22 2015-06-02 Ethicon Endo-Surgery, Inc. Methods and devices for activating brown adipose tissue using electrical energy
WO2011094573A1 (en) * 2010-01-28 2011-08-04 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル， インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
WO2011163347A2 (en) 2010-06-23 2011-12-29 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
EP2593014B1 (de) 2010-07-16 2015-11-04 Seventh Sense Biosystems, Inc. Niederdruckumgebung für flüssigkeitstransfervorrichtungen
WO2012021801A2 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
US9475709B2 (en) 2010-08-25 2016-10-25 Lockheed Martin Corporation Perforated graphene deionization or desalination
CN103370007B (zh) 2010-11-09 2018-12-18 第七感生物系统有限公司 用于采血的系统和界面
US9610429B2 (en) 2010-12-29 2017-04-04 Ethicon Endo-Surgery, Inc. Methods and devices for activating brown adipose tissue with targeted substance delivery
EP2701600B1 (de) 2011-04-29 2016-06-08 Seventh Sense Biosystems, Inc. Ausgabe und/oder aufnahme von flüssigkeiten
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
KR20140034200A (ko) 2011-04-29 2014-03-19 세븐쓰 센스 바이오시스템즈, 인크. 혈액 스폿들 또는 다른 신체 유체들을 수집 및/또는 조작하기 위한 시스템들 및 방법들
WO2012149155A1 (en) 2011-04-29 2012-11-01 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
EP2771059B1 (de) * 2011-10-27 2019-07-17 Sorrento Therapeutics, Inc. Transdermale freisetzung von hochviskosen bioaktiven wirkstoffen
US10653824B2 (en) 2012-05-25 2020-05-19 Lockheed Martin Corporation Two-dimensional materials and uses thereof
US9744617B2 (en) 2014-01-31 2017-08-29 Lockheed Martin Corporation Methods for perforating multi-layer graphene through ion bombardment
US9610546B2 (en) 2014-03-12 2017-04-04 Lockheed Martin Corporation Separation membranes formed from perforated graphene and methods for use thereof
US10203295B2 (en) 2016-04-14 2019-02-12 Lockheed Martin Corporation Methods for in situ monitoring and control of defect formation or healing
US9834809B2 (en) 2014-02-28 2017-12-05 Lockheed Martin Corporation Syringe for obtaining nano-sized materials for selective assays and related methods of use
US9005108B2 (en) 2012-09-27 2015-04-14 Palo Alto Research Center Incorporated Multiple reservoir drug delivery device and methods
US9999720B2 (en) 2012-09-27 2018-06-19 Palo Alto Research Center Incorporated Drug reconstitution and delivery device and methods
US9008389B2 (en) * 2012-09-28 2015-04-14 Robert D. Williams System and method for determining the amount of vitamin D generated by a user
AU2013364053B2 (en) 2012-12-21 2018-08-30 Corium Pharma Solutions, Inc. Microarray for delivery of therapeutic agent and methods of use
US9744341B2 (en) 2013-01-15 2017-08-29 Palo Alto Research Center Incorporated Devices and methods for intraluminal retention and drug delivery
BR122020006959B1 (pt) 2013-03-12 2022-04-26 Corium, Inc Aplicador de microprojeções
TW201504140A (zh) 2013-03-12 2015-02-01 Lockheed Corp 形成具有均勻孔尺寸之多孔石墨烯之方法
BR112015022625B1 (pt) 2013-03-15 2023-01-31 Corium, Inc Aparelho de microestrutura para entrega de agente terapêutico
EP2968119B1 (de) 2013-03-15 2019-09-18 Corium International, Inc. Mikroarray zur freisetzung therapeutischer wirkstoffe, verfahren zur verwendung und verfahren zur herstellung
JP2016514133A (ja) 2013-03-15 2016-05-19 コリウム インターナショナル， インコーポレイテッド ポリマーを含まない微細構造物を含むマイクロアレイ、製造方法および使用方法
CA2903459C (en) 2013-03-15 2024-02-20 Corium International, Inc. Multiple impact microprojection applicators and methods of use
EP2994189A4 (de) * 2013-05-06 2017-01-18 Mupharma Pty Ltd Nichtinvasiver wirkstoffapplikator
US9572918B2 (en) 2013-06-21 2017-02-21 Lockheed Martin Corporation Graphene-based filter for isolating a substance from blood
US9297083B2 (en) 2013-12-16 2016-03-29 Palo Alto Research Center Incorporated Electrolytic gas generating devices, actuators, and methods
CA2938305A1 (en) 2014-01-31 2015-08-06 Lockheed Martin Corporation Processes for forming composite structures with a two-dimensional material using a porous, non-sacrificial supporting layer
SG11201606289RA (en) 2014-01-31 2016-08-30 Lockheed Corp Perforating two-dimensional materials using broad ion field
JP2017512129A (ja) 2014-03-12 2017-05-18 ロッキード・マーチン・コーポレーション 有孔グラフェンから形成された分離膜
US20170056637A1 (en) 2014-05-06 2017-03-02 Mupharma Pty Ltd Non-invasive agent applicator
EP3158342B1 (de) 2014-06-19 2020-09-09 Life Technologies Corporation Verfahren mit festem puffer
US9801660B2 (en) 2014-07-31 2017-10-31 Palo Alto Research Center Incorporated Implantable fluid delivery devices, systems, and methods
US10278675B2 (en) 2014-07-31 2019-05-07 Palo Alto Research Center Incorporated Implantable estrus detection devices, systems, and methods
KR20170095804A (ko) 2014-09-02 2017-08-23 록히드 마틴 코포레이션 이차원 막 소재에 기반을 둔 혈액 투석 및 혈액 여과 막과 이를 이용하는 방법
EP3188714A1 (de) 2014-09-04 2017-07-12 Corium International, Inc. Mikrostrukturanordnung, verfahren zur herstellung und verfahren zur verwendung
JP5967595B2 (ja) * 2014-09-08 2016-08-10 株式会社かいわ 穿刺器具
KR200483166Y1 (ko) * 2014-11-03 2017-04-21 (주)아모레퍼시픽 무선전기 공급을 받아 작동되는 침패치를 부착한 마스크팩
JP6020771B2 (ja) * 2014-11-06 2016-11-02 凸版印刷株式会社 経皮投与デバイス、および、経皮投与デバイスの製造方法
AU2015346003A1 (en) 2014-11-12 2017-05-25 Mupharma Pty Ltd Non-invasive agent applicator
US10080884B2 (en) 2014-12-29 2018-09-25 Ethicon Llc Methods and devices for activating brown adipose tissue using electrical energy
US10092738B2 (en) 2014-12-29 2018-10-09 Ethicon Llc Methods and devices for inhibiting nerves when activating brown adipose tissue
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
JP2018528144A (ja) 2015-08-05 2018-09-27 ロッキード・マーチン・コーポレーション グラフェン系材料の穿孔可能なシート
WO2017023377A1 (en) 2015-08-06 2017-02-09 Lockheed Martin Corporation Nanoparticle modification and perforation of graphene
SG11201809015WA (en) 2016-04-14 2018-11-29 Lockheed Corp Two-dimensional membrane structures having flow passages
WO2017180135A1 (en) 2016-04-14 2017-10-19 Lockheed Martin Corporation Membranes with tunable selectivity
CA3020686A1 (en) 2016-04-14 2017-10-19 Lockheed Martin Corporation Method for treating graphene sheets for large-scale transfer using free-float method
SG11201809016QA (en) 2016-04-14 2018-11-29 Lockheed Corp Selective interfacial mitigation of graphene defects
WO2017180134A1 (en) 2016-04-14 2017-10-19 Lockheed Martin Corporation Methods for in vivo and in vitro use of graphene and other two-dimensional materials
EP3338853A1 (de) 2016-12-23 2018-06-27 Sanofi-Aventis Deutschland GmbH Medikamentenverabreichungsvorrichtung
WO2019104326A1 (en) 2017-11-27 2019-05-31 Prostacare Pty Ltd An apparatus and a method for the treatment of a prostatic disease
WO2019168949A1 (en) 2018-02-28 2019-09-06 Prostacare Pty Ltd System for managing high impedance changes in a non-thermal ablation system for bph
US11666741B1 (en) * 2021-06-01 2023-06-06 TruCelium Inc. Method for delivering matter into the human body

Family Cites Families (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1017883B (de) 1954-07-08 1957-10-17 Fellows Gear Shaper Co Schalt- und Vorschubeinrichtung fuer Zahnradherstellungsmaschinen
US3315665A (en) 1963-10-11 1967-04-25 Norman A Macleod Method and apparatus for therapy of skin tissue
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
CA1029288A (en) 1973-05-29 1978-04-11 William J. O'malley Silicone pressure-sensitive adhesive
US4231372A (en) 1974-11-04 1980-11-04 Valleylab, Inc. Safety monitoring circuit for electrosurgical unit
US4071028A (en) 1976-02-17 1978-01-31 Perkins George C Radio frequency cautery instrument and control unit therefor
US4141359A (en) 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4301794A (en) 1978-10-18 1981-11-24 Robert Tapper Method for iontophoretic treatment
US4340047A (en) 1978-10-18 1982-07-20 Robert Tapper Iontophoretic treatment apparatus
DE3050386C2 (de) 1980-05-13 1987-06-25 American Hospital Supply Corp Multipolare elektrochirurgische Vorrichtung
US4674499A (en) 1980-12-08 1987-06-23 Pao David S C Coaxial bipolar probe
US4805616A (en) 1980-12-08 1989-02-21 Pao David S C Bipolar probes for ophthalmic surgery and methods of performing anterior capsulotomy
US4406658A (en) 1981-03-06 1983-09-27 Medtronic, Inc. Iontophoretic device with reversible polarity
US4925671A (en) 1981-11-24 1990-05-15 Flexcon Company, Inc. Silicone pressure sensitive adhesive and uses
US5385544A (en) 1992-08-12 1995-01-31 Vidamed, Inc. BPH ablation method and apparatus
JPS60174716A (ja) 1984-02-21 1985-09-09 Yamanouchi Pharmaceut Co Ltd パツチ剤
US4747819A (en) 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
US4655767A (en) 1984-10-29 1987-04-07 Dow Corning Corporation Transdermal drug delivery devices with amine-resistant silicone adhesives
US4655766A (en) 1985-08-01 1987-04-07 Alza Corporation Fluid imbibing pump with self-regulating skin patch
US4744788A (en) 1986-01-13 1988-05-17 Mercer Jr Leo C Method of using a surgical clip for cholangiography
US4722726A (en) 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
US4752285B1 (en) 1986-03-19 1995-08-22 Univ Utah Res Found Methods and apparatus for iontophoresis application of medicaments
US4767402A (en) 1986-07-08 1988-08-30 Massachusetts Institute Of Technology Ultrasound enhancement of transdermal drug delivery
US5042975A (en) 1986-07-25 1991-08-27 Rutgers, The State University Of New Jersey Iontotherapeutic device and process and iontotherapeutic unit dose
US4935346A (en) 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
US4731049A (en) 1987-01-30 1988-03-15 Ionics, Incorporated Cell for electrically controlled transdermal drug delivery
US5013293A (en) 1987-05-28 1991-05-07 Drug Delivery Systems Inc. Pulsating transdermal drug delivery system
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4898920A (en) 1987-10-15 1990-02-06 Dow Corning Corporation Adhesive compositions, controlled release compositions and transdermal delivery device
JP2798459B2 (ja) 1988-01-21 1998-09-17 マサチユセツツ・インスチチユート・オブ・テクノロジー エレクトロポレーションを利用した診断装置及び分子の組織内移動装置
US5547467A (en) 1988-01-21 1996-08-20 Massachusettes Institute Of Technology Method for rapid temporal control of molecular transport across tissue
US5749847A (en) 1988-01-21 1998-05-12 Massachusetts Institute Of Technology Delivery of nucleotides into organisms by electroporation
KR970011449B1 (ko) 1988-01-29 1997-07-11 더 리전트 오브 디 유니버시티 오브 캘리포니아 이온전기 영동형 비침입 검체 채취 또는 이송 장치 및 방법
US5362307A (en) 1989-01-24 1994-11-08 The Regents Of The University Of California Method for the iontophoretic non-invasive-determination of the in vivo concentration level of an inorganic or organic substance
US4994267A (en) 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
US5438984A (en) 1988-09-08 1995-08-08 Sudor Partners Apparatus and method for the collection of analytes on a dermal patch
US4927408A (en) 1988-10-03 1990-05-22 Alza Corporation Electrotransport transdermal system
US5496266A (en) 1990-04-30 1996-03-05 Alza Corporation Device and method of iontophoretic drug delivery
US5125928A (en) 1989-04-13 1992-06-30 Everest Medical Corporation Ablation catheter with selectively deployable electrodes
US4979948A (en) 1989-04-13 1990-12-25 Purdue Research Foundation Method and apparatus for thermally destroying a layer of an organ
US5135478A (en) 1989-05-10 1992-08-04 Drug Delivery Systems Inc. Multi-signal electrical transdermal drug applicator
US5252334A (en) 1989-09-08 1993-10-12 Cygnus Therapeutic Systems Solid matrix system for transdermal drug delivery
EP0429842B1 (de) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
US5036861A (en) 1990-01-11 1991-08-06 Sembrowich Walter L Method and apparatus for non-invasively monitoring plasma glucose levels
US5147916A (en) 1990-02-21 1992-09-15 Dow Corning Corporation Hot-melt silicone pressure sensitive adhesive composition and related methods and articles
US5115805A (en) 1990-02-23 1992-05-26 Cygnus Therapeutic Systems Ultrasound-enhanced delivery of materials into and through the skin
US5098430A (en) 1990-03-16 1992-03-24 Beacon Laboratories, Inc. Dual mode electrosurgical pencil
US5125894A (en) 1990-03-30 1992-06-30 Alza Corporation Method and apparatus for controlled environment electrotransport
US5213568A (en) 1990-03-30 1993-05-25 Medtronic Inc. Activity controlled electrotransport drug delivery device
US5162410A (en) 1990-04-13 1992-11-10 Dow Corning Corporation Hot-melt silicon pressure sensitive adhesives with phenyl-containing siloxane fluid additive and related methods and articles
US5282799A (en) 1990-08-24 1994-02-01 Everest Medical Corporation Bipolar electrosurgical scalpel with paired loop electrodes
DE4032471C2 (de) 1990-10-12 1997-02-06 Delma Elektro Med App Elektrochirurgische Vorrichtung
US5224927A (en) 1990-11-01 1993-07-06 Robert Tapper Iontophoretic treatment system
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
US5156591A (en) 1990-12-13 1992-10-20 S. I. Scientific Innovations Ltd. Skin electrode construction and transdermal drug delivery device utilizing same
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
SE9101022D0 (sv) 1991-01-09 1991-04-08 Paal Svedman Medicinsk suganordning
US5182938A (en) 1991-02-22 1993-02-02 Nordson Corporation Method and apparatus for detecting bubbles in pressurized liquid dispensing systems
US5571149A (en) 1991-05-21 1996-11-05 E.P., Inc. Non-intrusive analgesic neuroaugmentive and iontophoretic delivery apparatus and management system
US5383917A (en) 1991-07-05 1995-01-24 Jawahar M. Desai Device and method for multi-phase radio-frequency ablation
US5232702A (en) 1991-07-22 1993-08-03 Dow Corning Corporation Silicone pressure sensitive adhesive compositons for transdermal drug delivery devices and related medical devices
CA2088652C (en) 1992-02-03 2008-07-29 Yeung S. Yu Improved oxidative coupling dye for spectrophotometric quantitative analysis of analytes
JP2572823Y2 (ja) 1992-02-13 1998-05-25 株式会社アドバンス 簡易採血器
GB9204218D0 (en) 1992-02-27 1992-04-08 Goble Nigel M A surgical cutting tool
US5540681A (en) 1992-04-10 1996-07-30 Medtronic Cardiorhythm Method and system for radiofrequency ablation of tissue
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US5542916A (en) 1992-08-12 1996-08-06 Vidamed, Inc. Dual-channel RF power delivery system
JPH0670987A (ja) 1992-08-28 1994-03-15 Katsuro Tachibana 薬物投与・体液採取ユニット及び装置
US5545161A (en) 1992-12-01 1996-08-13 Cardiac Pathways Corporation Catheter for RF ablation having cooled electrode with electrically insulated sleeve
US5614502A (en) 1993-01-15 1997-03-25 The General Hospital Corporation High-pressure impulse transient drug delivery for the treatment of proliferative diseases
US5993434A (en) 1993-04-01 1999-11-30 Genetronics, Inc. Method of treatment using electroporation mediated delivery of drugs and genes
US5533971A (en) 1993-09-03 1996-07-09 Alza Corporation Reduction of skin irritation during electrotransport
US5540669A (en) 1993-09-30 1996-07-30 Becton, Dickinson And Company Iontophoretic drug delivery system and method for using same
US5653892A (en) 1994-04-04 1997-08-05 Texas Instruments Incorporated Etching of ceramic materials with an elevated thin film
KR0134152B1 (ko) 1994-05-23 1998-04-14 이형도 의약품 투여용 피부흠집 형성장치
US5771890A (en) 1994-06-24 1998-06-30 Cygnus, Inc. Device and method for sampling of substances using alternating polarity
US5609151A (en) 1994-09-08 1997-03-11 Medtronic, Inc. Method for R-F ablation
US5563031A (en) 1994-09-08 1996-10-08 Lifescan, Inc. Highly stable oxidative coupling dye for spectrophotometric determination of analytes
US5514130A (en) 1994-10-11 1996-05-07 Dorsal Med International RF apparatus for controlled depth ablation of soft tissue
US5785705A (en) 1994-10-11 1998-07-28 Oratec Interventions, Inc. RF method for controlled depth ablation of soft tissue
NO180024C (no) 1994-10-11 1997-01-29 Oerjan G Martinsen Måling av fuktighet i hud
ATE177325T1 (de) * 1994-12-09 1999-03-15 Novartis Erfind Verwalt Gmbh Transdermales system
US5897553A (en) 1995-11-02 1999-04-27 Medtronic, Inc. Ball point fluid-assisted electrocautery device
US5573778A (en) 1995-03-17 1996-11-12 Adhesives Research, Inc. Drug flux enhancer-tolerant pressure sensitive adhesive composition
US5853383A (en) 1995-05-03 1998-12-29 Alza Corporation Preparation for formulations for electrotransport drug delivery
DE19525607A1 (de) * 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
US5780050A (en) 1995-07-20 1998-07-14 Theratech, Inc. Drug delivery compositions for improved stability of steroids
US5693052A (en) 1995-09-01 1997-12-02 Megadyne Medical Products, Inc. Coated bipolar electrocautery
US5735273A (en) 1995-09-12 1998-04-07 Cygnus, Inc. Chemical signal-impermeable mask
AU722471B2 (en) 1995-10-17 2000-08-03 Lifescan, Inc. Blood glucose strip having reduced sensitivity to hematocrit
ZA975326B (en) * 1996-06-18 1998-01-14 Alza Corp Device and method for enhancing transdermal flux of agents being delivered or sampled.
US5869326A (en) 1996-09-09 1999-02-09 Genetronics, Inc. Electroporation employing user-configured pulsing scheme
US5893885A (en) 1996-11-01 1999-04-13 Cordis Webster, Inc. Multi-electrode ablation catheter
ES2195190T3 (es) * 1996-12-20 2003-12-01 Alza Corp Dispositivo y metodo para mejorar el flujo de agente transdermico.
US6055043A (en) 1997-06-05 2000-04-25 Gn Nettest New York, Inc. Method and apparatus for using phase modulation to reduce coherence/polarization noise in reflectometers
US6117660A (en) 1997-06-10 2000-09-12 Cytopulse Sciences, Inc. Method and apparatus for treating materials with electrical fields having varying orientations
US6055453A (en) 1997-08-01 2000-04-25 Genetronics, Inc. Apparatus for addressing needle array electrodes for electroporation therapy
KR100572539B1 (ko) * 1997-12-11 2006-04-24 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
CA2313698C (en) * 1997-12-11 2008-04-15 Alza Corporation Device for enhancing transdermal agent flux
US6120493A (en) 1998-01-27 2000-09-19 Genetronics, Inc. Method for the introduction of therapeutic agents utilizing an electroporation apparatus
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction

Also Published As

Publication number Publication date
CA2341446C (en) 2008-10-07
CA2341446A1 (en) 2000-03-09
JP2002523195A (ja) 2002-07-30
WO2000012173A1 (en) 2000-03-09
CN1315877A (zh) 2001-10-03
DE69921489D1 (de) 2004-12-02
US20020115957A1 (en) 2002-08-22
DE69921489T2 (de) 2005-10-27
US6532386B2 (en) 2003-03-11
EP1109594B1 (de) 2004-10-27
EP1109594A1 (de) 2001-06-27

Similar Documents

Publication Publication Date Title
DE69921489D1 (de) Elektrotransportvorrichtung mit klingen
DE69905437D1 (de) Zelle mit nichtwässrigem Elektrolyt
DE60137042D1 (de) Vorrichtungen zur probenverarbeitung
NO156810C (no) Elektrodeunderlag for elektrokjemisk celle.
ES519731A0 (es) Un dispositivo posicionador de anodos para una celda de reduccion electrolitica.
IT7925928A0 (it) Catodo per una cella elettrochimica, e cella elettrochimica.
DE69903721D1 (de) Pem-brennstoffzellenanordnung mit mehreren parallel angeordneten brennstoffzellen-teilstapeln
DE69938557D1 (de) Verbesserte membranelektrodenanordnung für pem-brennstoffzelle
DE69927867D1 (de) System zum Integrieren von privaten Kommunikationsendgeräten
ES2044872T3 (es) Memoria semicionductora.
DE69927508D1 (de) Hebezeug zum transportieren von plattenstapeln
GB0325095D0 (en) A coplanar waveguide line
DE69515655D1 (de) Gesintertes, poröses, nickel-beschichtetes Substrat aus Eisen für Elektroden in alkalischen sekundären Batterien
ES521962A0 (es) Un dispositivo de conexion de cables electricos, especialmente para redes de suministro de electricidad de tension baja y media.
WO2003093410A3 (en) Fluorinated glucosamine analogs useful for modulating post-translational glycosylations on cells
WO2002013287A3 (de) Elektrochemische zelle mit polymerelektrolytmembran
SE0202795D0 (sv) Bränslecell
ITTO981102A0 (it) Listello portatappi per batterie e batterie includenti tale listello.
ITBO990374A0 (it) Macchina sezionatrice con apparecchiatura per realizzare il corretto a llineamento tra una sega circolare ed un relativo incisore .
ES518462A0 (es) Un metodo para hacer reaccionar electroquimicamente un liquido con un gas en una celda electroquimica.
IT1312161B1 (it) Carrello, in particolare per apparecchi di sollevamento.
SE9704065D0 (sv) Betongskydd för anodnät
NO151307C (no) Anordning ved krokorienterer, saakalt splitter, til bruk i et lineinnhalingssystem.
NO20003598D0 (no) Bærer for en elektrisk kontaktanordning
ATE233954T1 (de) Brennstoffzelle mit polymerelektrolyt

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties