MX2009012273A - Dispositivos de suministro transd?rmico que aseguran la liberaci?n mejorada de un principio activo a trav?s de una interfaz biol?gica. - Google Patents

Dispositivos de suministro transd?rmico que aseguran la liberaci?n mejorada de un principio activo a trav?s de una interfaz biol?gica.

Info

Publication number
MX2009012273A
MX2009012273A MX2009012273A MX2009012273A MX2009012273A MX 2009012273 A MX2009012273 A MX 2009012273A MX 2009012273 A MX2009012273 A MX 2009012273A MX 2009012273 A MX2009012273 A MX 2009012273A MX 2009012273 A MX2009012273 A MX 2009012273A
Authority
MX
Mexico
Prior art keywords
transdermal delivery
biological interface
delivery devices
active principle
improved release
Prior art date
Application number
MX2009012273A
Other languages
English (en)
Inventor
Kiyoshi Kanamura
Chizuko Ishikawa
Izumi Ishikawa
Mayuko Ishida
Youhei Nomoto
Akiyoshi Saito
Original Assignee
Tti Ellebeau Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tti Ellebeau Inc filed Critical Tti Ellebeau Inc
Publication of MX2009012273A publication Critical patent/MX2009012273A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/473Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Abstract

Se proporciona un sistema de suministro transd?rmico de f?rmaco para el suministro transd?rmico pasivo de uno o m?s agentes activos ionizables a la interfaz biol?gica de un sujeto. El sistema de suministro transde?rmico de f?rmaco incluye un sustrato de soporte, y una capa de agente activo. La capa activa incluye un agente espesante, un plastificante y una cantidad terap?uticamente efectiva de un agente activo ionizable.
MX2009012273A 2007-05-18 2008-05-16 Dispositivos de suministro transd?rmico que aseguran la liberaci?n mejorada de un principio activo a trav?s de una interfaz biol?gica. MX2009012273A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US93896107P 2007-05-18 2007-05-18
US95585007P 2007-08-14 2007-08-14
US95689507P 2007-08-20 2007-08-20
US95712607P 2007-08-21 2007-08-21
PCT/US2008/063979 WO2008144565A1 (en) 2007-05-18 2008-05-16 Transdermal delivery devices assuring an improved release of an active principle through a biological interface

Publications (1)

Publication Number Publication Date
MX2009012273A true MX2009012273A (es) 2010-04-09

Family

ID=39712735

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009012273A MX2009012273A (es) 2007-05-18 2008-05-16 Dispositivos de suministro transd?rmico que aseguran la liberaci?n mejorada de un principio activo a trav?s de una interfaz biol?gica.

Country Status (13)

Country Link
US (1) US20080286349A1 (es)
EP (1) EP2157970A1 (es)
JP (1) JP5489988B2 (es)
KR (1) KR20100020008A (es)
CN (1) CN101801359B (es)
AU (1) AU2008254748A1 (es)
CA (1) CA2686286A1 (es)
IL (1) IL201920A0 (es)
MX (1) MX2009012273A (es)
NZ (1) NZ582049A (es)
RU (1) RU2482841C2 (es)
TW (1) TW200902091A (es)
WO (1) WO2008144565A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2497679C2 (ru) 2008-10-02 2013-11-10 Милан Инк. Способ получения многослойного клеящегося ламинированного материала
CN107884561A (zh) 2012-04-04 2018-04-06 辛辛那提大学 汗液模拟、收集和感测系统
DK3202769T3 (da) * 2012-05-24 2019-10-28 Phosplatin Therapeutics Llc Fremgangsmåde til oprensning af phosphaplatinforbindelser
CN105848564B (zh) 2013-10-18 2020-12-25 辛辛那提大学 用于集成的、重复的、长时间、和/或可靠汗液刺激及生物感测的装置
AU2014337151A1 (en) 2013-10-18 2016-05-05 University Of Cincinnati Sweat sensing with chronological assurance
US10888244B2 (en) 2013-10-18 2021-01-12 University Of Cincinnati Sweat sensing with chronological assurance
EP3148430A4 (en) 2014-05-28 2018-05-16 University of Cincinnati Advanced sweat sensor adhesion, sealing, and fluidic strategies
WO2015184084A2 (en) * 2014-05-28 2015-12-03 University Of Cincinnati Sweat monitoring and control of drug delivery
AU2015266956A1 (en) 2014-05-28 2016-12-15 University Of Cincinnati Devices with reduced sweat volumes between sensors and sweat glands
US9687455B2 (en) 2014-08-14 2017-06-27 John Daniel Dobak Sodium tetradecyl sulfate formulations for treatment of adipose tissue
CN107205643B (zh) 2014-09-22 2021-11-23 辛辛那提大学 具有分析保证的汗液传感
CN107249471B (zh) 2015-02-13 2020-01-17 辛辛那提大学 集成间接汗液刺激和感测的装置
US9351945B1 (en) 2015-02-27 2016-05-31 John Daniel Dobak, III Reduction of adipose tissue
US10646142B2 (en) 2015-06-29 2020-05-12 Eccrine Systems, Inc. Smart sweat stimulation and sensing devices
WO2017070640A1 (en) 2015-10-23 2017-04-27 Eccrine Systems, Inc. Devices capable of sample concentration for extended sensing of sweat analytes
US10674946B2 (en) 2015-12-18 2020-06-09 Eccrine Systems, Inc. Sweat sensing devices with sensor abrasion protection
US10471249B2 (en) 2016-06-08 2019-11-12 University Of Cincinnati Enhanced analyte access through epithelial tissue
WO2018006087A1 (en) 2016-07-01 2018-01-04 University Of Cincinnati Devices with reduced microfluidic volume between sensors and sweat glands
US10405794B2 (en) 2016-07-19 2019-09-10 Eccrine Systems, Inc. Sweat conductivity, volumetric sweat rate, and galvanic skin response devices and applications
US10736565B2 (en) 2016-10-14 2020-08-11 Eccrine Systems, Inc. Sweat electrolyte loss monitoring devices

Family Cites Families (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4022776A (en) * 1974-01-31 1977-05-10 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxycarbostyril derivatives
DE2626294C3 (de) * 1976-06-11 1980-01-10 Siemens Ag, 1000 Berlin Und 8000 Muenchen Implantierbare Dosiereinrichtung
US4374168A (en) * 1981-11-06 1983-02-15 The H. A. Montgomery Co., Inc. Metalworking lubrication
NL8220476A (nl) * 1982-11-17 1984-09-03 Chevron Research Company Te San Francisco, Californie, Ver. St. V. Am. Elektroactieve polymeren.
US5135477A (en) * 1984-10-29 1992-08-04 Medtronic, Inc. Iontophoretic drug delivery
US4585652A (en) * 1984-11-19 1986-04-29 Regents Of The University Of Minnesota Electrochemical controlled release drug delivery system
US4915685A (en) * 1986-03-19 1990-04-10 Petelenz Tomasz J Methods and apparatus for iontophoresis application of medicaments at a controlled ph through ion exchange
US5080646A (en) * 1988-10-03 1992-01-14 Alza Corporation Membrane for electrotransport transdermal drug delivery
FR2635979B1 (fr) * 1988-09-07 1992-05-29 Lhd Lab Hygiene Dietetique Dispositif auto-adhesif d'administration d'un principe actif par voie percutanee
US4927408A (en) * 1988-10-03 1990-05-22 Alza Corporation Electrotransport transdermal system
CA1338779C (en) * 1989-03-17 1996-12-10 Harry Hind Method for treating pain associated with herpes-zoster and post-herpetic neuralgia by topical application of local anesthetics
US5334138A (en) * 1990-03-15 1994-08-02 North Carolina State University Method and composition for increased skin concentration of active agents by iontophoresis
US5084006A (en) * 1990-03-30 1992-01-28 Alza Corporation Iontopheretic delivery device
ES2072134T3 (es) * 1990-10-29 1995-07-01 Alza Corp Electrodo iontoforetico para suministrar farmacos y metodo para su hidratacion.
US5160790A (en) * 1990-11-01 1992-11-03 C. R. Bard, Inc. Lubricious hydrogel coatings
JPH08774B1 (es) * 1990-11-09 1996-01-10
US5405317A (en) * 1991-05-03 1995-04-11 Alza Corporation Iontophoretic delivery device
US5203768A (en) * 1991-07-24 1993-04-20 Alza Corporation Transdermal delivery device
US5405614A (en) * 1992-04-08 1995-04-11 International Medical Associates, Inc. Electronic transdermal drug delivery system
US5310404A (en) * 1992-06-01 1994-05-10 Alza Corporation Iontophoretic delivery device and method of hydrating same
ES2108282T3 (es) * 1992-06-02 1997-12-16 Alza Corp Aparato para la liberacion iontoforetica de farmacos.
US5489624A (en) * 1992-12-01 1996-02-06 Minnesota Mining And Manufacturing Company Hydrophilic pressure sensitive adhesives
US5306504A (en) * 1992-12-09 1994-04-26 Paper Manufactures Company Skin adhesive hydrogel, its preparation and uses
US5298017A (en) * 1992-12-29 1994-03-29 Alza Corporation Layered electrotransport drug delivery system
US5380272A (en) * 1993-01-28 1995-01-10 Scientific Innovations Ltd. Transcutaneous drug delivery applicator
US5415866A (en) * 1993-07-12 1995-05-16 Zook; Gerald P. Topical drug delivery system
FR2709423B1 (fr) * 1993-08-30 1995-11-17 Lhd Lab Hygiene Dietetique Réservoir imprégnable d'une solution de principe actif, pour dispositif ionophorétique d'administration transdermique de médicaments, et procédé de fabrication d'un tel réservoir.
US6377847B1 (en) * 1993-09-30 2002-04-23 Vyteris, Inc. Iontophoretic drug delivery device and reservoir and method of making same
US6190691B1 (en) * 1994-04-12 2001-02-20 Adolor Corporation Methods for treating inflammatory conditions
DE4416927C1 (de) * 1994-05-13 1995-08-31 Lohmann Therapie Syst Lts Vorrichtung zur Abgabe von Wirkstoffen aus Haftschmelzklebern, Verfahren zu ihrer Herstellung und ihre Verwendung
US6048545A (en) * 1994-06-24 2000-04-11 Biozone Laboratories, Inc. Liposomal delivery by iontophoresis
US5607940A (en) * 1994-07-18 1997-03-04 Stephen; Robert L. Morphine formulations for use by electromotive administration
WO1996010439A1 (fr) * 1994-09-30 1996-04-11 Kabushiki Kaisya Advance Interface pour administration iontophoretique transcutanee, et agent et methode de traitement de la peau a cette fin
US20020048596A1 (en) * 1994-12-30 2002-04-25 Gregor Cevc Preparation for the transport of an active substance across barriers
JPH11503043A (ja) * 1995-04-07 1999-03-23 ノバルティス・アクチエンゲゼルシャフト 少なくとも2種の被投与物を投与するためのイオン泳動性経皮システム
US6425892B2 (en) * 1995-06-05 2002-07-30 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
US20060024359A1 (en) * 1995-06-07 2006-02-02 Walker Jeffrey P Drug delivery system and method
US5891581A (en) * 1995-09-07 1999-04-06 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Thermally stable, piezoelectric and pyroelectric polymeric substrates
US5733269A (en) * 1996-03-15 1998-03-31 Fuisz Technologies Ltd. Method and kit for positioning transdermal delivery system
GB9614902D0 (en) * 1996-07-16 1996-09-04 Rhodes John Sustained release composition
US5738647A (en) * 1996-09-27 1998-04-14 Becton Dickinson And Company User activated iontophoretic device and method for activating same
US6350259B1 (en) * 1996-09-30 2002-02-26 Vyteris, Inc. Selected drug delivery profiles using competing ions
FR2755372B1 (fr) * 1996-11-07 1998-12-24 Elf Aquitaine Dispositif d'ionophorese comportant au moins un ensemble electrode a membrane, pour l'administration transcutanee de principes actifs a un sujet
US5980898A (en) * 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US20060002959A1 (en) * 1996-11-14 2006-01-05 Government Of The United States Skin-sctive adjuvants for transcutaneous immuization
GB9712347D0 (en) * 1997-06-14 1997-08-13 Smithkline Beecham Biolog Vaccine
KR19990026792A (ko) * 1997-09-26 1999-04-15 김윤 디클로페낙 디에틸암모늄염을 함유한 매트릭스형 패취제제
US5882677A (en) * 1997-09-30 1999-03-16 Becton Dickinson And Company Iontophoretic patch with hydrogel reservoir
US6039977A (en) * 1997-12-09 2000-03-21 Alza Corporation Pharmaceutical hydrogel formulations, and associated drug delivery devices and methods
US6197324B1 (en) * 1997-12-18 2001-03-06 C. R. Bard, Inc. System and methods for local delivery of an agent
EP1109594B1 (en) * 1998-08-31 2004-10-27 Johnson & Johnson Consumer Companies, Inc. Electrotransport device comprising blades
US6858018B1 (en) * 1998-09-28 2005-02-22 Vyteris, Inc. Iontophoretic devices
WO2000062857A1 (en) * 1999-04-16 2000-10-26 Johnson & Johnson Consumer Companies, Inc. Electrotransport delivery system comprising internal sensors
US6692456B1 (en) * 1999-06-08 2004-02-17 Altea Therapeutics Corporation Apparatus for microporation of biological membranes using thin film tissue interface devices, and method therefor
US6375963B1 (en) * 1999-06-16 2002-04-23 Michael A. Repka Bioadhesive hot-melt extruded film for topical and mucosal adhesion applications and drug delivery and process for preparation thereof
US6394994B1 (en) * 1999-08-27 2002-05-28 Vyteris, Inc. Method for testing the ability of an iontophoretic reservoir-electrode to deliver a medicament
JP4414517B2 (ja) * 1999-09-01 2010-02-10 久光製薬株式会社 イオントフォレーシス用デバイス構造体
US6348558B1 (en) * 1999-12-10 2002-02-19 Shearwater Corporation Hydrolytically degradable polymers and hydrogels made therefrom
HU229550B1 (en) * 2000-06-27 2014-01-28 Hoffmann La Roche Method for preparing compositions
AU2001283359A1 (en) * 2000-08-14 2002-02-25 Pharmacia Corporation Drug release (delivery system)
US6560483B1 (en) * 2000-10-18 2003-05-06 Minnesota High-Tech Resources, Llc Iontophoretic delivery patch
EP1385571B1 (en) * 2001-04-04 2008-07-30 Alza Corporation Transdermal electrotransport delivery device including an antimicrobial compatible reservoir composition
US7052706B2 (en) * 2001-06-08 2006-05-30 Nostrum Pharmaceuticals, Inc. Control release formulation containing a hydrophobic material as the sustained release agent
US6723077B2 (en) * 2001-09-28 2004-04-20 Hewlett-Packard Development Company, L.P. Cutaneous administration system
US20030068361A1 (en) * 2001-10-09 2003-04-10 Rimona Margalit Liposome-encapsulated insulin formulations
EP1440707A4 (en) * 2001-10-31 2006-05-24 Transcutaneous Tech Inc IONOPHORESIS DEVICE
ES2500117T3 (es) * 2002-02-22 2014-09-30 Shire Llc Novedosos compuestos farmacéuticos de liberación sostenida para prevenir el abuso de sustancias controladas
US6861410B1 (en) * 2002-03-21 2005-03-01 Chiron Corporation Immunological adjuvant compositions
US20060009730A2 (en) * 2002-07-29 2006-01-12 Eemso, Inc. Iontophoretic Transdermal Delivery of One or More Therapeutic Agents
US7150975B2 (en) * 2002-08-19 2006-12-19 Animas Technologies, Llc Hydrogel composition for measuring glucose flux
JP4642467B2 (ja) * 2002-08-20 2011-03-02 ユーロ−セルティーク エス.エイ. 活性剤及び塩並びに副作用物質の遊離塩基形を含む経皮剤形
US8734421B2 (en) * 2003-06-30 2014-05-27 Johnson & Johnson Consumer Companies, Inc. Methods of treating pores on the skin with electricity
AR051397A1 (es) * 2004-10-21 2007-01-10 Novartis Ag Composicion farmaceutica
US20060095001A1 (en) * 2004-10-29 2006-05-04 Transcutaneous Technologies Inc. Electrode and iontophoresis device
JP2006346368A (ja) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc イオントフォレーシス装置及びその製造方法
JP2007000342A (ja) * 2005-06-23 2007-01-11 Transcutaneous Technologies Inc 複数薬剤の投与量および投与時期を制御するイオントフォレーシス装置
US20070027426A1 (en) * 2005-06-24 2007-02-01 Transcutaneous Technologies Inc. Iontophoresis device to deliver active agents to biological interfaces
US8295922B2 (en) * 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US8386030B2 (en) * 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US20070088331A1 (en) * 2005-08-18 2007-04-19 Transcutaneous Technologies Inc. Method and apparatus for managing active agent usage, and active agent injecting device
US20070060860A1 (en) * 2005-08-18 2007-03-15 Transcutaneous Technologies Inc. Iontophoresis device
US20070088332A1 (en) * 2005-08-22 2007-04-19 Transcutaneous Technologies Inc. Iontophoresis device
US20070048362A1 (en) * 2005-08-29 2007-03-01 Transcutaneous Technologies Inc. General purpose electrolyte solution composition for iontophoresis
RU2008114490A (ru) * 2005-09-15 2009-10-20 ТиТиАй ЭЛЛЕБО, ИНК. (JP) Устройство ионтофореза стержневого типа
WO2007038028A1 (en) * 2005-09-28 2007-04-05 Tti Ellebeau, Inc. Iontophoresis apparatus and method to deliver active agents to biological interfaces
US20070071807A1 (en) * 2005-09-28 2007-03-29 Hidero Akiyama Capsule-type drug-releasing device and capsule-type drug-releasing device system
KR20080066712A (ko) * 2005-09-30 2008-07-16 티티아이 엘뷰 가부시키가이샤 관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법
WO2007041115A1 (en) * 2005-09-30 2007-04-12 Tti Ellebeau Inc. Method and system to detect malfunctions in an iontophoresis device that delivers active agents to biological interfaces
JP2009509659A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 生体界面への活性物質の送達のイオントフォレーシス装置及び方法
US20070093789A1 (en) * 2005-09-30 2007-04-26 Transcutaneous Technologies Inc. Iontophoresis apparatus and method for delivery of angiogenic factors to enhance healing of injured tissue
BRPI0616771A2 (pt) * 2005-09-30 2011-06-28 Tti Ellebeau Inc dispositivo de iontoforese para liberar múltiplos agentes ativos para interfaces biológicas
WO2007041539A1 (en) * 2005-09-30 2007-04-12 Transcutaneous Technologies, Inc. Iontophoresis apparatus and method for the diagnosis of tuberculosis
JP2009509677A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 小胞封入活性物質のイオントフォレーシス送達
EP1928539A1 (en) * 2005-09-30 2008-06-11 Tti Ellebeau, Inc. Functionalized microneedles transdermal drug delivery systems, devices, and methods
WO2007041300A2 (en) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Iontophoresis method and apparatus for systemic delivery of active agents
WO2007041526A2 (en) * 2005-09-30 2007-04-12 Transcutaneous Technologies Inc. Iontophoresis apparatus and method to deliver antibiotics to biological interfaces
US20070078445A1 (en) * 2005-09-30 2007-04-05 Curt Malloy Synchronization apparatus and method for iontophoresis device to deliver active agents to biological interfaces
JP2009509657A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 生体界面への活性物質の送達のイオントフォレーシス装置及び方法
WO2007041314A2 (en) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Transdermal drug delivery systems, devices, and methods employing novel pharmaceutical vehicles
US20070078375A1 (en) * 2005-09-30 2007-04-05 Transcutaneous Technologies Inc. Iontophoretic delivery of active agents conjugated to nanoparticles
WO2007079116A1 (en) * 2005-12-28 2007-07-12 Tti Ellebeau, Inc. Electroosmotic pump apparatus and method to deliver active agents to biological interfaces
US7848801B2 (en) * 2005-12-30 2010-12-07 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
US20080004564A1 (en) * 2006-03-30 2008-01-03 Transcutaneous Technologies Inc. Controlled release membrane and methods of use
CN101495105A (zh) * 2006-07-05 2009-07-29 Tti优而美株式会社 具有自组装树枝状聚合物的输送装置及其使用方法

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RU2009145645A (ru) 2011-06-27
CN101801359B (zh) 2013-11-06
AU2008254748A1 (en) 2008-11-27
US20080286349A1 (en) 2008-11-20
RU2482841C2 (ru) 2013-05-27
NZ582049A (en) 2012-12-21
KR20100020008A (ko) 2010-02-19
JP5489988B2 (ja) 2014-05-14
WO2008144565A1 (en) 2008-11-27
IL201920A0 (en) 2010-06-16
JP2010527934A (ja) 2010-08-19
CA2686286A1 (en) 2008-11-27
EP2157970A1 (en) 2010-03-03
CN101801359A (zh) 2010-08-11

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